Pathogens, Vol. 9, Pages 408: Role of Hydrogen Peroxide Vapor (HPV) for the Disinfection of Hospital Surfaces Contaminated by Multiresistant Bacteria Pathogens doi: 10.3390/pathogens9050408 Authors: Michele Totaro Beatrice Casini Sara Profeti Benedetta Tuvo Gaetano Privitera Angelo Baggiani The emergence of multiresistant bacterial strains as agents of healthcare-related infection in hospitals has prompted a review of the control techniques, with an added emphasis on preventive...
Pathogens, Vol. 9, Pages 407: Analysis of the Leukocyte Response in Calves Suffered from Mycoplasma bovis Pneumonia Pathogens doi: 10.3390/pathogens9050407 Authors: Katarzyna Dudek Dariusz Bednarek Urszula Lisiecka Anna Kycko Michał Reichert Krzysztof Kostro Stanisław Winiarczyk Mycoplasma bovis is known to be a cause of chronic pneumonia in cattle. To date, the disease pathomechanism has not been fully elucidated. Leukocytes play a key role in host antimicrobial defense...
Pathogens, Vol. 9, Pages 406: Barcoding of the Genus Culicoides (Diptera: Ceratopogonidae) in Austria–An Update of the Species Inventory Including the First Records of Three Species in Austria Pathogens doi: 10.3390/pathogens9050406 Authors: Zittra Wöss Van der Vloet Bakran-Lebl Shahi Barogh Sehnal Fuehrer Ceratopogonidae are small nematoceran Diptera with a worldwide distribution, consisting of more than 5400 described species, divided into 125 genera. The...
Pathogens, Vol. 9, Pages 405: Drug Discovery against Acanthamoeba Infections: Present Knowledge and Unmet Needs Pathogens doi: 10.3390/pathogens9050405 Authors: Hany M. Elsheikha Ruqaiyyah Siddiqui Naveed Ahmed Khan Although major strides have been made in developing and testing various anti-acanthamoebic drugs, recurrent infections, inadequate treatment outcomes, health complications, and side effects associated with the use of currently available drugs necessitate the development...
Pathogens, Vol. 9, Pages 403: The Relationship between Estrogen-Related Signaling and Human Papillomavirus Positive Cancers Pathogens doi: 10.3390/pathogens9050403 Authors: Claire D. James Iain M. Morgan Molly L. Bristol High risk-human papillomaviruses (HPVs) are known carcinogens. Numerous reports have linked the steroid hormone estrogen, and the expression of estrogen receptors (ERs), to HPV-related cancers, although the exact nature of the interactions remains to be fully elucidated....
Pathogens, Vol. 9, Pages 404: A Review: Wolbachia-Based Population Replacement for Mosquito Control Shares Common Points with Genetically Modified Control Approaches Pathogens doi: 10.3390/pathogens9050404 Authors: Pei-Shi Yen Anna-Bella Failloux The growing expansion of mosquito vectors has made mosquito-borne arboviral diseases a global threat to public health, and the lack of licensed vaccines and treatments highlight the urgent need for efficient mosquito vector control. Compared...
Pathogens, Vol. 9, Pages 402: A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation Pathogens doi: 10.3390/pathogens9050402 Authors: Kristen A. Johnson Rudramani Pokhrel Melissa R. Budicini Bernard S. Gerstman Prem P. Chapagain Robert V. Stahelin The Ebola virus (EBOV) harbors seven genes, one of which is the matrix protein eVP40, a peripheral protein that is sufficient to induce the formation...
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Pharmaceuticals, Vol. 13, Pages 103: Constructing Auxin-Inducible Degron Mutants Using an All-in-One Vector Pharmaceuticals doi: 10.3390/ph13050103 Authors: Aisha Yesbolatova Yuichiro Saito Masato T. Kanemaki Conditional degron-based methods are powerful for studying protein function because a degron-fused protein can be rapidly and efficiently depleted by adding a defined ligand. Auxin-inducible degron (AID) is a popular technology by which a degron-fused protein can be degraded...
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Pharmaceutics, Vol. 12, Pages 478: Caffeic Acid Phenethyl Ester Assisted by Reversible Electroporation—In Vitro Study on Human Melanoma Cells Pharmaceutics doi: 10.3390/pharmaceutics12050478 Authors: Anna Choromanska Jolanta Saczko Julita Kulbacka Melanoma is one of the most serious skin cancers. The incidence of this malignant skin lesion is continuing to increase worldwide. Melanoma is resistant to chemotherapeutic drugs and highly metastatic. Surgical resection can only be used...
Pharmaceutics, Vol. 12, Pages 479: Injectable SN-38-embedded Polymeric Microparticles Promote Antitumor Efficacy against Malignant Glioma in an Animal Model Pharmaceutics doi: 10.3390/pharmaceutics12050479 Authors: Yuan-Yun Tseng Tao-Chieh Yang Shu-Mei Chen Shun-Tai Yang Ya-Ling Tang Shih-Jung Liu Malignant glioma (MG) is extremely aggressive and highly resistant to chemotherapeutic agents. Using electrospraying, the potent chemotherapeutic agent 7-ethyl-10-hydroxycamptothecia...
Pharmaceutics, Vol. 12, Pages 477: In Vitro Antigenotoxic, Antihelminthic and Antioxidant Potentials Based on the Extracted Metabolites from Lichen, Candelariella vitellina Pharmaceutics doi: 10.3390/pharmaceutics12050477 Authors: Islam El-Garawani Mahmoud Emam Waill Elkhateeb Hesham El-Seedi Shaden Khalifa Salwa Oshiba Shaimaa Abou-Ghanima Ghoson Daba Lichens have recently received great attention due to their pharmacological potentials. The antigenotoxic potential...
Pharmaceutics, Vol. 12, Pages 476: Optimization of Curcumin Nanocrystals as Promising Strategy for Nose-to-Brain Delivery Application Pharmaceutics doi: 10.3390/pharmaceutics12050476 Authors: Angela Bonaccorso Maria Rosa Gigliobianco Rosalia Pellitteri Debora Santonocito Claudia Carbone Piera Di Martino Giovanni Puglisi Teresa Musumeci Intranasal (IN) drug delivery is recognized to be an innovative strategy to deliver drugs to the Central Nervous System. One of the...
Pharmaceutics, Vol. 12, Pages 475: Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I2-Imidazoline Receptor Ligand MCR5 Pharmaceutics doi: 10.3390/pharmaceutics12050475 Authors: Foteini Vasilopoulou Andrea Bagan Sergio Rodriguez-Arevalo Carmen Escolano Christian Griñán-Ferré Mercè Pallàs Behavioural and psychological symptoms of dementia (BPSD), including fear-anxiety- and depressive-like...
Pharmaceutics, Vol. 12, Pages 474: Therapeutic Use of Mesenchymal Stem Cell-Derived Exosomes: From Basic Science to Clinics Pharmaceutics doi: 10.3390/pharmaceutics12050474 Authors: Carl Randall Harrell Nemanja Jovicic Valentin Djonov Vladislav Volarevic Mesenchymal stem cells (MSC) are, due to their immunosuppressive and regenerative properties, used as new therapeutic agents in cell-based therapy of inflammatory and degenerative diseases. A large number of experimental and...
Pharmaceutics, Vol. 12, Pages 473: Stepwise Glucoheptoamidation of Poly(Amidoamine) Dendrimer G3 to Tune Physicochemical Properties of the Potential Drug Carrier: In Vitro Tests for Cytisine Conjugates Pharmaceutics doi: 10.3390/pharmaceutics12050473 Authors: Anna Czerniecka-Kubicka Piotr Tutka Marek Pyda Małgorzata Walczak Łukasz Uram Maria Misiorek Ewelina Chmiel Stanisław Wołowiec Third-generation poly(amidoamine) dendrimer (PAMAM) was modified by stepwise primary...
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Pharmacy, Vol. 8, Pages 89: The Role of Community Pharmacists in the Detection of Clinically Relevant Drug-Related Problems in Chronic Kidney Disease Patients Pharmacy doi: 10.3390/pharmacy8020089 Authors: Céline Mongaret Léa Aubert Amélie Lestrille Victorine Albaut Pierre Kreit Emmanuelle Herlem Natacha Noel Fatouma Touré François Lallier Florian Slimano the MIRPhO Investigators Study Community pharmacists (CPs) have traditionally had limited access to...
Pharmacy, Vol. 8, Pages 88: Description of Position Ads for Pharmacy Technicians Pharmacy doi: 10.3390/pharmacy8020088 Authors: Juanita A. Draime Emily C. Wicker Zachary J. Krauss Joel L. Sweeney Douglas C. Anderson Pharmacy technician roles are evolving alongside the changing role of a pharmacist. There is currently no uniform definition of a pharmacy technician’s role in the pharmacy workforce. The objective of this study was to look at the United States-based...
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Plants, Vol. 9, Pages 666: Identification and Molecular Characterization of Geranyl Diphosphate Synthase (GPPS) Genes in Wintersweet Flower Plants doi: 10.3390/plants9050666 Authors: Hafiz Muhammad Kamran Syed Bilal Hussain Shang Junzhong Lin Xiang Long-Qing Chen Geranyl diphosphate synthase (GPPS) is a plastid localized enzyme that catalyzes the biosynthesis of Geranyl diphosphate (GPP), which is a universal precursor of monoterpenes. Wintersweet (Chimonanthus praecox L.),...
Plants, Vol. 9, Pages 664: Characterization of Atypical Protein Tyrosine Kinase (PTK) Genes and Their Role in Abiotic Stress Response in Rice Plants doi: 10.3390/plants9050664 Authors: Allimuthu Dalal Kumar Sellathdurai Kumar Sathee Chinnusamy Tyrosine phosphorylation constitutes up to 5% of the total phophoproteome. However, only limited studies are available on protein tyrosine kinases (PTKs) that catalyze protein tyrosine phosphorylation in plants. In this...
Plants, Vol. 9, Pages 665: Development and Optimization of a Germination Assay and Long-Term Storage for Cannabis sativa Pollen Plants doi: 10.3390/plants9050665 Authors: Gaudet Yadav Sorokin Bilichak Kovalchuk Pollen viability and storage is of great interest to cannabis breeders and researchers to maintain desirable germplasm for future use in breeding or for biotechnological and gene editing applications. Here, we report a simple and efficient cryopreservation method...
Plants, Vol. 9, Pages 663: Normal Cyclic Variation in CO2 Concentration in Indoor Chambers Decreases Leaf Gas Exchange and Plant Growth Plants doi: 10.3390/plants9050663 Authors: James Bunce Attempts to identify crop genetic material with larger growth stimulation at projected elevated atmospheric CO2 concentrations are becoming more common. The probability of reductions in photosynthesis and yield caused by short-term variation in CO2 concentration within elevated CO2 treatments in...
Plants, Vol. 9, Pages 661: Effects of Water Regime, Genotype, and Formative Stages on the Agro-Physiological Response of Sugarcane (Saccharum officinarum L.) to Drought Plants doi: 10.3390/plants9050661 Authors: Reyes Carpentero Santos Delfin Drought during the formative stages of a plant’s growth triggers a sequence of responses to maintain optimal growing conditions, but often at the expense of crop productivity. Two field experiments were conducted to determine...
Plants, Vol. 9, Pages 662: Structural Adaptation and Physiological Mechanisms in the Leaves of Anthyllis vulneraria L. from Metallicolous and Non-Metallicolous Populations Plants doi: 10.3390/plants9050662 Authors: Marzena Sujkowska-Rybkowska Ewa Muszyńska Mateusz Labudda Calamine wastes highly contaminated with trace metals (TMs) are spontaneously inhabited by a legume plant Anthyllis vulneraria L. This study determined an adaptation strategy of metallicolous (M) A. vulneraria...
Plants, Vol. 9, Pages 660: A Study on the Effect of Macro- and Micro- Nutrients on Nannochloropsis oceanica Growth, Fatty Acid Composition and Magnetic Harvesting Efficiency Plants doi: 10.3390/plants9050660 Authors: Maria G. Savvidou Elenitsa Boli Dimitrios Logothetis Theopisti Lymperopoulou Angelo Ferraro Vasiliki Louli Diomi Mamma Dimitris Kekos Kostis Magoulas Fragiskos N. Kolisis The effect of iron, manganese, phosphorus and nitrogen on growth and lipid...
Plants, Vol. 9, Pages 658: Investigation of Indigenous Arbuscular Mycorrhizal Performance Using a Lotus japonicus Mycorrhizal Mutant Plants doi: 10.3390/plants9050658 Authors: Teranishi Kobae Most plants are usually colonized with arbuscular mycorrhiza fungi (AMF) in the fields. AMF absorb mineral nutrients, especially phosphate, from the soil and transfer them to the host plants. Inoculation with exotic AMF is thought to be effective when indigenous AMF performance is low; however,...
Plants, Vol. 9, Pages 656: Micropropagation, Genetic Fidelity and Phenolic Compound Production of Rheum rhabarbarum L. Plants doi: 10.3390/plants9050656 Authors: Clapa Borsai Hârța Bonta Szabo Coman Bobiș An efficient micropropagation protocol for Rheum rhabarbarum L. was developed in this study. The in vitro rhubarb plants obtained in the multiplication stage (proliferation rate: 5.0 ± 0.5) were rooted in vitro (96% rooting percentage) and acclimatized...
Plants, Vol. 9, Pages 657: Phytoremediation Potential, Photosynthetic and Antioxidant Response to Arsenic-Induced Stress of Dactylis glomerata L. Sown on Fly Ash Deposits Plants doi: 10.3390/plants9050657 Authors: Gajić Djurdjević Kostić Jarić Stevanović Mitrović Pavlović Arsenic (As) from coal fly ash can be released into soil/groundwater, presenting a global threat to the environment and human health. To overcome this environmental problem, phytoremediation...
Plants, Vol. 9, Pages 659: Designing a Clean Label Fish Patty with Olive, Citric, Pomegranate, or Rosemary Extracts Plants doi: 10.3390/plants9050659 Authors: Martínez-Zamora Ros Nieto The natural functional ingredients derived from pomegranate (41.4% punicalagin), rosemary (5.8% carnosic acid and carnosol), hydroxytyrosol (7.3%), and citrus (55% hesperidin) fruits were combined separately with acerola (17% vitamin C) and essential oils rich in fatty acids (45% α-linolenic...
Plants, Vol. 9, Pages 655: Insecticidal Activity of Hyoscyamus niger L. on Lucilia sericata Causing Myiasis Plants doi: 10.3390/plants9050655 Authors: Esra Küpeli Akkol Mert Ilhan Esma Kozan Fatma Tuğçe Gürağaç Dereli Mustafa Sak Eduardo Sobarzo-Sánchez Background: Hyoscyamus niger L. (Solanaceae) generally known as henbane, is commonly distributed in Europe and Asia. In Turkey, henbane seeds have been used in folk medicine to remove worms from the eyes. The present study...
Plants, Vol. 9, Pages 654: Characterization of Colletotrichum ocimi Population Associated with Black Spot of Sweet Basil (Ocimum basilicum) in Northern Italy Plants doi: 10.3390/plants9050654 Authors: Santa Olga Cacciola Giovanna Gilardi Roberto Faedda Leonardo Schena Antonella Pane Angelo Garibaldi Maria Lodovica Gullino Black spot is a major foliar disease of sweet basil (Ocimum basilicum) present in a typical cultivation area of northern Italy, including the Liguria...
Plants, Vol. 9, Pages 653: MicroRNA156 (miR156) Negatively Impacts Mg-Protoporphyrin IX (Mg-Proto IX) Biosynthesis and Its Plastid-Nucleus Retrograde Signaling in Apple Plants doi: 10.3390/plants9050653 Authors: Qingbo Zheng Yakun Chen Xiaolin Jia Yi Wang Ting Wu Xuefeng Xu Zhenhai Han Zhihong Zhang Xinzhong Zhang Plastid-nucleus retrograde signaling (PNRS) play essential roles in regulating nuclear gene expression during plant growth and development. Excessive...
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Prosthesis, Vol. 2, Pages 65-75: Fluid-Structure Interaction Analysis of Subject-Specific Mitral Valve Regurgitation Treatment with an Intra-Valvular Spacer Prosthesis doi: 10.3390/prosthesis2020007 Authors: Milan Toma Daniel R. Einstein Charles H. Bloodworth Keshav Kohli Richard P. Cochran Karyn S. Kunzelman Ajit P. Yoganathan Mitral regurgitation imposes a significant symptomatic burden on patients who are not candidates for conventional surgery. For these patients,...
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Proteomes, Vol. 8, Pages 12: Is It Possible to Find Needles in a Haystack? Meta-Analysis of 1000+ MS/MS Files Provided by the Russian Proteomic Consortium for Mining Missing Proteins Proteomes doi: 10.3390/proteomes8020012 Authors: Ekaterina Poverennaya Olga Kiseleva Ekaterina Ilgisonis Svetlana Novikova Arthur Kopylov Yuri Ivanov Alexei Kononikhin Mikhail Gorshkov Nikolay Kushlinskii Alexander Archakov Elena Ponomarenko Despite direct or indirect efforts...
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Religions, Vol. 11, Pages 265: The Basis for Coexistence Found from within: The Mystic Universality and Ethicality of Donghak (東學, Eastern Learning) Religions doi: 10.3390/rel11050265 Authors: Haeyoung Seong The rush of Western civilization, headed by Christianity, caused a considerable identity crisis in the 19th century Joseon dynasty. The founder of Donghak 東學, Suun Choe Je-u 水雲 崔濟愚, sought a way out of the crisis through religion. Suun contended that the religions of both east and...
Religions, Vol. 11, Pages 264: Augustine and Xunzi on Human Dignity and Human Rights: The Worth of Being Human and Its Entitlement to Institutional Measures for Protecting the Access to Human Flourishing Religions doi: 10.3390/rel11050264 Authors: Eun Young Hwang While some human rights theorists suggest that the universalistic project of human rights can be consistent only with an individualistic conception of dignity aligned with liberal regimes, there have also been some voices of...
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Resources, Vol. 9, Pages 60: Strategies for the Valorisation of Chestnut Resources in Italian Mountainous Areas from a Sustainable Development Perspective Resources doi: 10.3390/resources9050060 Authors: Stefano Bruzzese Simone Blanc Filippo Brun The chestnut tree has characterised the social history of the Italian hills and mountains. However, in recent years, this resource has been abandoned because of the change in socio-economic needs. The aim of this study is twofold: (i)...
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Risks, Vol. 8, Pages 53: Ruin Probability for Stochastic Flows of Financial Contract under Phase-Type Distribution Risks doi: 10.3390/risks8020053 Authors: Franck Adékambi Kokou Essiomle This paper examines the impact of the parameters of the distribution of the time at which a bank’s client defaults on their obligated payments, on the Lundberg adjustment coefficient, the upper and lower bounds of the ruin probability. We study the corresponding ruin probability on the assumption...
Risks, Vol. 8, Pages 52: Bankruptcy Prediction and Stress Quantification Using Support Vector Machine: Evidence from Indian Banks Risks doi: 10.3390/risks8020052 Authors: Santosh Kumar Shrivastav P. Janaki Ramudu Banks play a vital role in strengthening the financial system of a country; hence, their survival is decisive for the stability of national economies. Therefore, analyzing the survival probability of the banks is an essential and continuing research activity. However, the...
Risks, Vol. 8, Pages 51: Diversification and Desynchronicity: An Organizational Portfolio Perspective on Corporate Risk Reduction Risks doi: 10.3390/risks8020051 Authors: Xue-Feng Shao Kostas Gouliamos Ben Nan-Feng Luo Shigeyuki Hamori Stephen Satchell Xiao-Guang Yue Jane Qiu A longstanding objective of managers is to reduce risk to their businesses. The conventional strategy for risk reduction is diversification; however, evidence for the effectiveness of diversification...
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