Uro-oncology in times of COVID-19: The available evidence and recommendations in the Indian scenario
Tushar A Narain, Gagan Gautam, Amlesh Seth, Vikas K Panwar, Sudhir Rawal, Puneet Dhar, Harkirat S Talwar, Amitabh Singh, Jiten Jaipuria, Ankur MittalIndian Journal of Cancer 2020 57(2):129-138 The Corona Virus Disease-2019 (COVID-19), one of the most devastating pandemics ever, has left thousands of cancer patients to their fate. The future course of this pandemic is still an enigma, but health care services are expected to resume soon in a phased manner. This might be a long drawn process and...
Ashutosh Mukherji, Tejpal Gupta, Jai Prakash AgarwalIndian Journal of Cancer 2020 57(2):221-223 The practice of radiation oncology requires stringent adherence to specific steps and principles designed to minimize exposure of an individual to unnecessary doses of radiation. The basic principles of such measures to reduce the risk of exposure and limit the doses of irradiation follow the “as low as reasonably achievable ” or ALARA principle by using the concepts of time, distance and shielding....
HS Darling, Sameer RastogiIndian Journal of Cancer 2020 57(2):139-143 Globally, rare cancers as a group are commoner than any single common cancer. They represent an unmet medical need, and this issue gets further amplified in India due to various reasons, including the limited accessibility of healthcare system to the population at large. The scarce available data yet only represents the tip of the iceberg, due to poor registration and incomplete medical cover. Rare cancers, as a consequence,...
Sugandha, Naveen Kakkar, M Joseph JohnIndian Journal of Cancer 2020 57(2):201-204 Chronic neutrophilic leukemia is a rare leukemia seen in middle aged and elderly people, characterized by neutrophilic leukocytosis with no significant increase in granulocytic precursors. The chief criteria for diagnosis include total leukocyte count ≥25 × 109/L, >80% of white blood cells being mature neutrophils (segmented and band forms), immature granulocytic precursors ≥10% in the peripheral blood, and hypercellular...
Tanuja Shet, Trupti Pai, Tabassum Wadasadawala, Nita Nair, Seema GuliaIndian Journal of Cancer 2020 57(2):144-157 A histopathology report offers important prognostic and predictive information that helps plan systemic therapy in breast cancer. However, in many cases a pathologist fails to provide relevant information chiefly due to the lack of awareness of the impact of these parameters in clinical decision-making. This review seeks to put forth common practice points in grossing and reporting...
Ivan A Shtarbanov, Ivan K Boronsuzov, Ivan R Chakarov, Dobrin N KonstantinovIndian Journal of Cancer 2020 57(2):216-218
Umut Varol, Yusuf Uzum, Adem Sengul, Ugur Bayram Korkmaz, Murtaza Parvizi, Murat Akyol, Halil Taskaynatan, Tarik Salman, Utku Oflazoglu, Yasar Yildiz, Ahmet Alacacioglu, Yuksel Kucukzeybek, Mustafa Oktay TarhanIndian Journal of Cancer 2020 57(2):158-163 Background: Adjuvant treatment is necessary in pancreatic cancer patients, but the optimal approach is not clear yet. Our aim was to explore the effectiveness of adjuvant treatment modalities in patients with operated pancreatic cancer. Methods:...
Avinash Pande, Jyoti BajpaiIndian Journal of Cancer 2020 57(2):121-122
Rushabh KothariIndian Journal of Cancer 2020 57(2):164-165
HS Darling, S Jayalakshmi, Pradeep JaiswalIndian Journal of Cancer 2020 57(2):198-200
Keivan Moradi, Esmaeil Babaei, Nayebali Rezvani, Reza Safaralizadeh, Homayoun Bashiri, Mohammad Ali Hosseinpour FeiziIndian Journal of Cancer 2020 57(2):166-171 Background: Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim: The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor tissues and...
Neha Bakshi, Shashi Dhawan, Pratishtha Sengar, Ushast DhirIndian Journal of Cancer 2020 57(2):205-208 Intra-abdominal bronchogenic cysts are rare entities and only a handful of cases occurring within the lesser sac have been described. Further, the development of malignancy in a bronchogenic cyst is exceptional and one arising in a lesser sac has so far not been reported. We present herein an account of a 44-year-old man who presented with recurrent upper abdominal pain. Investigations revealed...
Vishnu Ramanujan, Arvind Krishnamurthy, Karthik Venkataramani, Chandra KumarIndian Journal of Cancer 2020 57(2):172-181 Background: Despite the advances in systemic treatment, about 30%–40% of the patients with extremity osteosarcomas relapse and more than 80% of these relapses localize in the lungs. Our understanding of the management of pulmonary metastases from extremity osteosarcomas is largely based on retrospective data from single institutions or compiled from registries; hence, there...
Neha ChauhanIndian Journal of Cancer 2020 57(2):212-215 Cancer therapy is undergoing rapid advancements and many of the conditions that were incurable earlier can now easily be treated. Making a “correct diagnosis” is the first step in the ladder towards treating the disease. However, once diagnosed, “breaking bad news” to the patient and his family that he/she has cancer is still a big challenge as it is a life-changing event not only for the patient but their families as well. The following...
Mridul Anand, Ankita Parikh, Sonal P ShahIndian Journal of Cancer 2020 57(2):182-186 Introduction: Pelvic radiotherapy is generally performed with the use of an immobilization and positioning device. Aim and objective: The objective of the study was to ascertain and compare setup errors between the two positioning devices. Materials and methods: A total of 35 patients of stage II and III cervical cancers were enrolled in the study and divided into two groups, one using knee wedge and...
Shreya Das Adhikari, Nitin Gupta, Atul Sharma, S V S Deo, Sushma BhatnagarIndian Journal of Cancer 2020 57(2):218-220
Ashna Nagpal, Sonali Verma, Ruchi Shah, Ghulam R Bhat, Amrita Bhat, Divya Bakshi, Bhanu Sharma, Sandeep Kaul, Rakesh KumarIndian Journal of Cancer 2020 57(2):187-189 Background: 8-Oxo-7, 8-dihydro-2'-deoxyguanosine (8-oxodG) is a potent DNA damage marker that leads to cellular oxidative stress. It is a DNA-repair enzyme that participates in “8-oxodG” DNA adducts removal. Previous studies show weak associations of rs1052133 (hOGG1) in breast cancer patients of Northern India. We performed this...
Indian Journal of Cancer 2020 57(2):224-227
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Authors: František Moravec and Jean-Lou Justine.<br />Parasite Vol. 27 , page 37<br />Published online: 19/05/2020<br /> Keywords: Nematode parasite ; Seuratoidea ; Mugiliformes ; Perciformes ; Tetraodontiformes ; South Pacific.<img src="http://feeds.feedburner.com/~r/edp_parasite/~4/Dl9pfjHFw8I" height="1" width="1" alt=""/>
Authors: Saw Bawm, Tay Zar Bhone Win, Shwe Yee Win, Lat Lat Htun, Ryo Nakao and Ken Katakura.<br />Parasite Vol. 27 , page 38<br />Published online: 19/05/2020<br /> Keywords: Eimeria arloingi ; Eimeria hirci ; Eimeria christenseni ; Domesticated goats ; Myanmar.<img src="http://feeds.feedburner.com/~r/edp_parasite/~4/4Sc7MZjWXvQ" height="1" width="1" alt=""/>
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Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background:Gastric cancer is one of the most common malignancies worldwide with high mortality. Therefore, identifying cancer-related biomarkers for predicting prognosis and progression of gastric cancer is essential. This study aimed to investigate the clinical value and functional role of microRNA-3196 in gastric cancer.Methods:The relative expression levels of microRNA-3196 in gastric cancer tissues and adjacent...
Mon May 18, 2020 13:38
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Primary brain tumors are a rare occurrence in comparison to other malignancies, the most predominant form being glioma. Commonly, exposure to ionizing radiations and inheritance of associated conditions such a neurofibromatosis and tuberous sclerosis are the most common causes of development of glioma. However, understanding of the molecular mechanisms that drive glioma development is limited. We explore the role...
Mon May 18, 2020 13:36
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Fernandes M Mevis, Sasidharanpillai Sabeena, Ramachandran Sanjay, Sudandiradas Robin, Santhosha Devadiga, Varamballi Prasad, Dsa Oliver, Alyusif Ameen, Govindakarnavar ArunkumarIndian Journal of Medical Microbiology 2019 37(4):563-568Purpose: Hepatitis E virus (HEV) is an emerging pathogen causing acute viral hepatitis worldwide. Clinical manifestations often occur in young adults with an increased mortality rate among pregnant women. HEV genotypes 1 and 4 are mainly reported among humans and swines,...
Sundaram Balasubramanian, Praachi Singh, K Dhanalakshmi, Sulochana Putlibai, Rosemol VargheseIndian Journal of Medical Microbiology 2019 37(4):598-599
Yamuna Devi Bakthavatchalam, Shoma Vinay Rao, Barney Isaac, Abi Manesh, Senthur Nambi, Subramanian Swaminathan, Vasanth Nagvekar, Vivek Nangia, Peter Victor John, Balaji VeeraraghavanIndian Journal of Medical Microbiology 2019 37(4):478-487Staphylococcus aureus is of significant clinical concern in both community- and hospital-onset infections. The key to the success of S. aureus as a pathogen is its ability to swiftly develop antimicrobial resistance. Methicillin-resistant S. aureus (MRSA) is not...
Immanuel Pradeep, Sneha Haridas Anupama, Priyanka Koshy, Abraham Kurien, Anusha Rohit, Milly Mathew, Rajeevalochana Parthasarathy, Georgi AbrahamIndian Journal of Medical Microbiology 2019 37(4):587-589 Mycobacterium tuberculosis(MTB)-related secondary immunoglobulin A (IgA) nephropathy is reported in a 72-year-old male patient. The patient was diagnosed to have MTB infection of the kidney and genitourinary tract which was diagnosed by the demonstration of the organism by GeneXpert Ultra and...
Chand Wattal, Neeraj Goel, Jaswinder Kaur Oberoi, Sanghamitra Datta, Reena RaveendranIndian Journal of Medical Microbiology 2019 37(4):488-495Objective: Commercially available antibiotic susceptibility tests (cAST) for colistin are reported to shows variable performance. The current controversy on the colistin susceptibility testing and scarce data from India has left the clinical laboratories in a dilemma on the appropriate and practical approach to tackle the colistin antimicrobial susceptibility...
Mousumi Dutta, Prafulla Dutta, Subhash Medhi, Biswajyoti Borkakoty, Dipankar BiswasIndian Journal of Medical Microbiology 2019 37(4):549-556Introduction: The pathogenicity of influenza virus infection is modulated by the cytokine expressions in patients. The present study was aimed to measure some important pro- and anti-inflammatory cytokines in influenza-infected population of Assam, Northeast India. Materials and Methods: Influenza viruses consisting of subtypes influenza A(H1N1)pdm09, H3N2 and...
Alphonsa Muth Thomas, Sukhwinder Kaur, Manisha Biswal, KL N Rao, Shashi VigIndian Journal of Medical Microbiology 2019 37(4):496-501Background: The WHO Multimodal Hand Hygiene Improvement Strategy (MHHIS) has been proposed to improve the Hand Hygiene (HH) compliance of the WHO recommendations on HH.Therefore, the current study was planned in our neonatal unit with the objective of evaluating the effectiveness of a Hand Hygiene Promotional Program (HHPP) based on the WHO MHHIS, in terms of compliance...
Veena Vadhini Ramalingam, Suganya Subramanian, G John Fletcher, Priscilla Rupali, George Varghese, Susanne Pulimood, Lakshmanan Jeyaseelan, Balaji Nandagopal, Gopalan Sridharan, Rajesh KannangaiIndian Journal of Medical Microbiology 2019 37(4):574-583Purpose: The sequence variation of human immunodeficiency virus (HIV) capsid region may influence and alter the susceptibility to human tripartite motif 5α protein (huTRIM5α). Materials and Methods: Molecular docking was carried out with huTRIM5α SPRY...
Ravi Indrapal Singh, Mohit Bhatia, KR Anusha, Vanya Singh, Balram Ji Omar, Pratima GuptaIndian Journal of Medical Microbiology 2019 37(4):502-508Context: As reports on colistin resistance are slowly emerging from different parts of the world, it is imperative that the clinical microbiology laboratories should generate accurate in vitro colistin susceptibility results. Aim: The aim is to generate preliminary data on the diagnostic utility of MicroScan WalkAway 96 Plus Identification ID/ Antimicrobial...
Vijeta Bajpai, Purva MathurIndian Journal of Medical Microbiology 2019 37(4):593-594
A Arunshankar, VJ Chandy, Divyaa Elangovan, TD Hariharan, John Antony Jude Prakash, Rahul George, Anil T Oommen, Pradeep M PoonnooseIndian Journal of Medical Microbiology 2019 37(4):509-513Background: Knowledge of the local microbiological epidemiology helps in formulating protocols for appropriate treatment of hip infections. The aim of this study was to profile the organisms cultured from infected hips. Methods: The microbiological profile and sensitivity pattern of organisms in eighty infected...
Parakriti Gupta, Kapil Goyal, Poonam Kanta, Arnab Ghosh, Mini P SinghIndian Journal of Medical Microbiology 2019 37(4):459-477An ongoing apocalyptic outbreak of a new virus causing pneumonia-like clusters in Wuhan city, China, has gleamed the world. The outbreak, confirmed on the New Year's Eve 2020, has known no boundaries since then. The number has surpassed that of Severe Acute Respiratory Syndrome (SARS) and Middle East respiratory syndrome (MERS), and is uninterruptedly escalating. Being an...
Abhinendra Kumar, Sharayu Mhatre, Rajesh DikshitIndian Journal of Medical Microbiology 2019 37(4):514-520Purpose: Identifying infectious pathogens by collecting intravenous blood (IVB) is a well-established procedure, however, the collection of IVB in field epidemiological study is challenging. The dried blood spot (DBS) as an alternative to IVB has been introduced, although, there is a limited study to demonstrate the utility of DBS stored at various storage conditions and transported at different...
Priyanka Wagh, Priyanka Kulkarni, Shilpa Kerkar, Hemant Tongaonkar, Kedar Deodhar, Bharat Rekhi, Vinita Salvi, Hemangi Chaudhari, Himangi Warke, Jayanti Mania-PramanikIndian Journal of Medical Microbiology 2019 37(4):557-562Background and Objectives: Human papillomavirus (HPV) is the causative agent of cervical cancer, a major cause of cancer mortality in Indian women. The current study was undertaken to add information to the existing data on HPV type distribution in Indians, in an attempt to document...
Tanu Singhal, Sweta Shah, Pooja Thakkar, Reshma NaikIndian Journal of Medical Microbiology 2019 37(4):521-526Background: There is a need to generate accurate data on temporal trends in incidence rates, aetiology and antimicrobial susceptibility of central line-associated bloodstream infections (CLABSIs) in the Indian setting. Aim: To study the incidence, aetiology and antimicrobial susceptibility of CLABSI in adult, paediatric and neonatal intensive care units (NICUs) in a tertiary care private hospital...
Swagatika Panda, Nirmal Kumar Mohakud, Soumya Panda, Subrat KumarIndian Journal of Medical Microbiology 2019 37(4):569-573Introduction: Human rhinovirus (HRV) and Enterovirus (ENV) are the major causes of childhood acute respiratory tract infections (ARTIs). This study sought to understand the distribution pattern of HRV subgroups, their seasonality and association with respiratory complications in patients at a tertiary care hospital. Results: Of the total 332 ARTI samples, 82 (24.7%) were positive...
Nargis Alom Choudhury, Deepjyoti Paul, Bhaskar Jyoti Das, Debadatta Dhar(Chanda), Amitabha BhattacharjeeIndian Journal of Medical Microbiology 2019 37(4):527-530Introduction: It was also known that the IncP-1 plasmids are ubiquitous in environmental bacteria and those reside in soil, sewage, marine sediments and in manure. The blaNDMis associated with resistance determinants along with various mobile elements such as plasmid, insertion sequences and transposons, which facilitates its horizontal dissemination....
Divyaa Elangovan, Susmitha Perumalla, Winsley Rose, Valsan Philip Verghese, Joy Mammen, MS Gowri, John Antony Jude PrakashIndian Journal of Medical Microbiology 2019 37(4):584-586Laboratory tests are necessary for diagnosis of scrub typhus (ST) especially in the absence of the distinctive eschar. Performance of an ELISA and ICT (immunochromatography) to detect IgM antibodies to scrub typhus was assessed using a panel of 346 sera chosen from healthy individuals, those with scrub typhus and scrub-typhus...
Rahul George, TD Hariharan, A Arunshankar, Divyaa Elangovan, Binesh Lal, VJ Chandy, AT Oommen, Pradeep Mathew PoonnooseIndian Journal of Medical Microbiology 2019 37(4):531-535Background: A single-stage implant revision for failed fixation of proximal femoral fractures is performed only when there is no evidence of infection. Else, a two-staged revision is preferred - where the definitive revision surgery is done a few months after the implant exit. This study aims to audit the safety and incidence...
Lata Sheoran, Neeraj Goel, Shankar Acharya, Nitin Adsul, Chand WattalIndian Journal of Medical Microbiology 2019 37(4):590-592 Spinal epidural abscess (SEA) due to Streptococcus pneumoniae is a rare entity, but it is associated with high mortality. Here, we describe a rare case of pneumococcal SEA in an immunocompetent adult who presented with fever, lower back pain and paresis. Central nervous system examination revealed a decreased power in bilateral lower limbs. Magnetic resonance imaging...
Sukhwinder Singh, Malini Rajinder Capoor, Swati Varshney, Dipendra Kumar Gupta, Pradeep Kumar Verma, V RameshIndian Journal of Medical Microbiology 2019 37(4):536-541Introduction: Over the past four decades, there has been an increase in the number of fatal opportunistic invasive trichosporonosis cases especially in immunocompromised hosts. Objective: The objective of the study is to evaluate the epidemiological, clinical details and antifungal susceptibility pattern of the patients with Trichosporon...
Deepak Juyal, Jyoti Rawre, Benu DhawanIndian Journal of Medical Microbiology 2019 37(4):595-597
Pallavi Ravindra Baliga, Raghavendran Anantharam, Vinotha Thomas, Priscilla Rupali, Manu Chopra, Susanne Pulimood, Jessie Lionel, Abraham Peedicayil, Rajesh Kannangai, Manu Gnanamony, Priya AbrahamIndian Journal of Medical Microbiology 2019 37(4):542-548Aims: Cervical cancer is one of the leading causes of cancer among women, worldwide. HIV-positive women tend to have persistent infection and infection with multiple human papillomavirus (HPV) types. There is a need for affordable HPV DNA tests as...
Rani Diana Sahni, Balaji Veeraraghavan, MS Dhiviya Prabaa, Jobin John JacobIndian Journal of Medical Microbiology 2019 37(4):600-601
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