The Effect of Prophylactic Central Neck Dissection During Hemithyroidectomy on Locoregional Recurrence in Patients With Papillary Thyroid Carcinoma: A Meta-Analysis. Clin Exp Otorhinolaryngol. 2020 May;13(2):194-202 Authors: Ahn SH, Kim WS Abstract OBJECTIVES: Hemithyroidectomy is commonly performed in patients with low- to intermediate-risk papillary thyroid carcinoma. The purpose of this meta-analysis was to evaluate the effect of prophylactic central...
The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis. Clin Exp Otorhinolaryngol. 2020 May;13(2):95-105 Authors: Park JH, Jang W, Kim SW, Lee J, Lim YS, Cho CG, Park SW, Kim BH Abstract OBJECTIVES: The objectives of this study were to identify the clinical features and chest computed tomography (CT) findings of coronavirus disease 2019 (COVID-19) patients...
Transoral Thyroidectomy: Is It a Real Game Changer? Clin Exp Otorhinolaryngol. 2020 May;13(2):93-94 Authors: Tae K PMID: 32434309 [PubMed]
Recent Trends in the Surgical Treatment of Secondary Hyperparathyroidism. Clin Exp Otorhinolaryngol. 2020 May;13(2):91-92 Authors: Won HR, Koo BS PMID: 32434308 [PubMed]
Unveiling the Diverse Spectrum of Fungal Rhinosinusitis. Clin Exp Otorhinolaryngol. 2020 May;13(2):89-90 Authors: Cho SH PMID: 32434307 [PubMed]
The Era of Precision Medicine: Reshaping Usher Syndrome. Clin Exp Otorhinolaryngol. 2020 May;13(2):87-88 Authors: Jung J PMID: 32434306 [PubMed]
Future Directions of Optical Coherence Tomography in Otology: A Morphological and Functional Approach. Clin Exp Otorhinolaryngol. 2020 May;13(2):85-86 Authors: Cho NH, Jang JH PMID: 32434305 [PubMed]
Does the Clinical Spectrum of Coronavirus Disease 2019 (COVID-19) Show Regional Differences? Clin Exp Otorhinolaryngol. 2020 May;13(2):83-84 Authors: Kim SY, Kim DW PMID: 32434304 [PubMed]
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Abstract Purpose: To evaluate the in vivo response of photobiomodulation therapy associated with norbixin-based poly(hydroxybutyrate) membrane (PHB) in tenotomized calcaneal tendon. Methods: Thirty rats were randomly allocated to six groups (n=5 each): LED groups (L1, L2 and L3) and membrane + LED groups (ML1, ML2 and ML3). The right calcaneal tendons of all animals were sectioned transversely and were irradiated with LED daily, one hour after surgery every 24 hours, until the day of euthanasia....
Abstract Purpose: The benefits of laparoscopic approaches to treat colorectal cancer (CRC) and colorectal liver metastases (CRLM) separately are well established. However, there is no consensus about the optimal timing to approach the primary tumor and CRLM, whether simultaneously or staged. The objective of this review with practical reports is to discuss technical aspects required for patient selection to perform simultaneous laparoscopic approaches for CRC and CRLM. Methods: Literature review...
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Background Nowadays, the most widely used types of wearable sensors in gait analysis are inertial sensors. The aim of the study was to assess the agreement between two different systems for measuring gait parameters (inertial sensor vs. electronic walkway) on healthy control subjects (HC) and patients with Parkinson’s disease (PD). Methods Forty healthy volunteers (26 men, 14 women, mean age 58.7 ± 7.7 years) participated...
Trauma and related fear exert significant influence on mental and physical health throughout the lifespan and are associated with intergenerational patterns of development, health, and behavior. DNA methylation and gene expression are involved in our developmental adaptations to our experiences and can be influenced by social interventions. Patterns of DNA methylation and expression of a gene involved in neurodevelopment and psychiatric risk (BDNF) have been linked with childhood trauma. Given the...
The new ichnospecies Paleohelcura araraquarensis isp. nov. is described from the Upper Jurassic-Lower Cretaceous Botucatu Formation of Brazil. This formation records a gigantic eolian sand sea (erg), formed under an arid climate in the south-central part of Gondwana. This trackway is composed of two track rows, whose internal width is less than one-quarter of the external width, with alternating to staggered series, consisting of three elliptical tracks that can vary from slightly elongated to tapered...
The animal’s blood is the most complicated and important biological liquid for veterinary medicine. In addition to standard methods that are always in use, recent technologies such as dynamic tensiometry (DT) of blood serum and PCR analysis of particular markers are in progress. The standard and modern biochemical tests are commonly used for general screening and, finally, complete diagnosis of animal health. Interpretation of major biochemical parameters is similar across animal species, but there...
Lizard and snake remains from the early Miocene (Burdigalian) of the Moghra Formation, Egypt, are described herein. This material comprises the first fossil remains of squamates recovered from the otherwise rich and well known vertebrate assemblage of Moghra. The material pertains to two different genera, the varanid lizard Varanus and the pythonid snake Python and adds to the so far rather poorly known squamate fossil record from Africa. On the basis of the new remains, Moghra marks the oldest so...
The horticulturally important genus Zantedeschia (Araceae) comprises eight species of herbaceous perennials. We sequenced, assembled and analyzed the chloroplast (cp) genomes of four species of Zantedeschia (Z. aethiopica, Z. odorata, Z. elliottiana, and Z. rehmannii) to investigate the structure of the cp genome in the genus. According to our results, the cp genome of Zantedeschia ranges in size from 169,065 bp (Z. aethiopica) to 175,906 bp (Z. elliottiana). We identified a total of 112 unique genes,...
Background Benzalkonium chloride (BAK), commonly used in glaucoma treatment, is an eye drop preservative with dose-dependent toxicity. Previous studies have observed the multi-functional benefits of angiogenin (ANG) against glaucoma. In our study, we evaluated ANG’s cytoprotective effect on the trabecular meshwork (TM) damage induced by BAK. Additionally, we developed a plant-derived ANG fusion protein and evaluated its effect on TM structure and function. Methods We synthesized plant-derived...
Background To study the peculiarities of changes in creatinine concentration in blood serum of untrained men during the prolonged usage of training loads different in volume and intensity, and to determine the value of this biochemical marker for the assessment of adaptive body changes during fitness training. Methods We examined 50 untrained men aged 18–20 years who had no contraindications for practicing fitness. Taking...
Background Human milk microbiota plays a role in the bacterial colonization of the neonatal gut, which has important consequences in the health and development of the newborn. However, there are few studies about the vertical transfer of bacteria from mother to infant in Latin American populations. Methods We performed a cross-sectional study characterizing the bacterial diversity of 67 human milk-neonatal stool pairs...
Background DNA double strand break repair is important to preserve the fidelity of our genetic makeup after DNA damage. Rad50 is one of the components in MRN complex important for DNA repair mechanism. Rad50 mutations can lead to microcephaly, mental retardation and growth retardation in human. However, Rad50 mutations in human and other organisms have never been gathered and heuristically compared for their deleterious effects. It is important to assess the conserved region in Rad50 and its homolog...
Background Stress reactivity can be different in women compared to men, which might consequently influence disease risk.Stress in women may also generate adverse physiological effects on their offspring during pregnancy or lactation. The objective of this study was to compare the effects of different relaxation interventions on physiological outcomes and perceived relaxation in healthy young women, to assist in identifying the most appropriate intervention(s) for use in a subsequent...
Here we give names to three new species of Paraburkholderia that can remain in symbiosis indefinitely in the spores of a soil dwelling eukaryote, Dictyostelium discoideum. The new species P. agricolaris sp. nov., P. hayleyella sp. nov., and P. bonniea sp. nov. are widespread across the eastern USA and were isolated as internal symbionts of wild-collected D. discoideum. We describe these sp. nov. using several approaches. Evidence that they are each a distinct new species comes from their phylogenetic...
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Background and Objectives To evaluate the safety and effectiveness of combined fractional radiofrequency microneedling (FRM) and fractional carbon dioxide (FCO2) laser treatment for striae distensae and to compare the results to those of FRM alone and those of FCO2 alone. Study Design/Materials and Methods Adult women (Fitzpatrick skin types III–IV) with striae distensae on the abdomen or calf were enrolled in this study. Each lesion was divided into three regions, with each region assigned...
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COVID-19 -associated Diffuse Leukoencephalopathy and Microhemorrhages. Radiology. 2020 May 21;:202040 Authors: Radmanesh A, Derman A, Lui YW, Raz E, Loh JP, Hagiwara M, Borja MJ, Zan E, Fatterpekar GM Abstract Coronavirus disease 2019 (COVID-19) has been reported in association with a variety of brain imaging findings such as ischemic infarct, hemorrhage, and acute hemorrhagic necrotizing encephalopathy. Here, we report brain imaging features in...
Imaging in Neurological Disease of Hospitalized COVID-19 Patients: An Italian Multicenter Retrospective Observational Study. Radiology. 2020 May 21;:201933 Authors: Mahammedi A, Saba L, Vagal A, Leali M, Rossi A, Gaskill M, Sengupta S, Zhang B, Carriero A, Bachir S, Crivelli P, Paschè A, Premi E, Padovani A, Gasparotti R PMID: 32437313 [PubMed - as supplied by publisher]
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Abstract Objectives The pooling of energetic resources and food sharing have been widely documented among hunter‐gatherer societies. Much less is known about how the energetic costs of daily activities are distributed across individuals in such groups, including between women and men. Moreover, the metabolic physiological correlates of those activities and costs are relatively understudied. Materials and methods Here, we tracked physical activity, energy expenditure (EE), and cortisol production...
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Abstract Purpose To determine whether rectal displacement devices (RDDs) have a prostate-stabilizing effect during prostate external beam radiotherapy (EBRT). Methods A systematic literature search using the PubMed database from January 1, 2000 to December 30th, 2019 was conducted. The effect of RDDs on inter- and intra-fractional prostate displacements...
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Quercetin postconditioning attenuates gastrocnemius muscle ischemia/reperfusion injury in rats. J Cell Physiol. 2020 May 21;: Authors: Mohammadrezaei Khorramabadi R, Anbari K, Salahshore M, Alasvand M, Assadollahi V, Gholami M Abstract Quercetin, an antioxidant derived from plants, can play a beneficial role in the protection of various tissues against ischemia-reperfusion injuries (IRI). The purpose of the present research was to investigate the protective...
Induced pluripotent stem cells (iPSCs) as game-changing tools in the treatment of neurodegenerative disease: Mirage or reality? J Cell Physiol. 2020 May 21;: Authors: Yousefi N, Abdollahii S, Kouhbanani MAJ, Hassanzadeh A Abstract Based on investigations, there exist tight correlations between neurodegenerative diseases' incidence and progression and aberrant protein aggregreferates in nervous tissue. However, the pathology of these diseases is not well...
Proteomic analysis of underlying apoptosis mechanisms of human retinal pigment epithelial ARPE-19 cells in response to mechanical stretch. J Cell Physiol. 2020 May 21;: Authors: Yan F, Gao M, Gong Y, Zhang L, Ai N, Zhang J, Chai Y, Wu S, Liu Q, Jiang X, Deng H, Liu W Abstract Our previous study demonstrated mechanical stretch (MS) could induce the apoptosis of retinal pigment epithelial (RPE) cells, but the related mechanisms remained unclear. This study...
Desferoxamine protects against glucocorticoid-induced osteonecrosis of the femoral head via activating HIF-1α expression. J Cell Physiol. 2020 May 21;: Authors: Jing X, Du T, Yang X, Zhang W, Wang G, Liu X, Li T, Jiang Z Abstract Glucocorticoid-induced osteonecrosis of the femoral head (GIOFH) is one of the most common complications of glucocorticoid administration. By chelating Fe2+ , desferoxamine (DFO) was reported to be able to activate the HIF-1α/VEGF...
Dehydroascorbic acid, the oxidized form of vitamin C, improves renal histology and function in old mice. J Cell Physiol. 2020 May 21;: Authors: Forman K, Martínez F, Cifuentes M, Fernández M, Bertinat R, Torres P, Salazar K, Godoy A, Nualart F Abstract Oxidative stress and inflammation are crucial factors that increase with age. In the progression of multiple age-related diseases, antioxidants and bioactive compounds have been recognized as useful antiaging...
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Novel Nomograms Individually Predicting Overall Survival of Non-metastatic Colon Cancer Patients. Front Oncol. 2020;10:733 Authors: Pei JP, Zhang CD, Liang Y, Zhang C, Wu KZ, Zhao ZM, Dai DQ Abstract Background: This study aimed to develop an effective prognostic nomogram for predicting non-metastatic colon cancer. Methods: The Surveillance, Epidemiology, and End Results program was utilized to analyze patients who underwent surgical therapy (25,350...
Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome. Front Oncol. 2020;10:721 Authors: Dai G, Jiang Z, Sun B, Liu C, Meng Q, Ding K, Jing W, Ju W Abstract Long-lasting inflammation in the intestinal tract renders individuals susceptible to colitis-associated cancer (CAC). The NOD-like receptor protein 3 (NLRP3) inflammasome plays a key role in the progression of inflammatory bowel disease and CAC. Therefore,...
CAR T Cells for Acute Myeloid Leukemia: State of the Art and Future Directions. Front Oncol. 2020;10:697 Authors: Mardiana S, Gill S Abstract Relapse after conventional chemotherapy remains a major problem in patients with myeloid malignancies such as acute myeloid leukemia (AML), and the major cause of death after diagnosis of AML is from relapsed disease. The only potentially curative treatment option currently available is allogeneic hematopoietic...
The E3 Ubiquitin Ligase Cbl-b Predicts Favorable Prognosis in Breast Cancer. Front Oncol. 2020;10:695 Authors: Liu X, Teng Y, Wu X, Li Z, Bao B, Liu Y, Qu X, Zhang L Abstract Background: Casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) is an E3 ubiquitin-protein ligase and a signal-transducing adaptor protein involved in the development and progression of cancer. Despite the known functions of Cbl-b, its role in breast cancer remains unclear. The...
Follow-Up of Head and Neck Cancer Survivors: Tipping the Balance of Intensity. Front Oncol. 2020;10:688 Authors: Szturz P, Van Laer C, Simon C, Van Gestel D, Bourhis J, Vermorken JB Abstract The traditional concept of post-treatment surveillance in head and neck cancer patients relies on examinations directed at early detection of disease recurrence and/or second primary tumors. They are usually provided by ear, nose and throat specialists with complementary...
The Role of Immunotherapy in Non-transplant Eligible Multiple Myeloma. Front Oncol. 2020;10:676 Authors: Bobin A, Gardeney H, Sabirou F, Gruchet C, Lévy A, Nsiala L, Cailly L, Tomowiak C, Torregrosa J, Guidez S, Leleu X Abstract As the global population is aging and survival in multiple myeloma (MM) is increasing, treating older MM patients, redefined as non-transplant eligible (NTE), is becoming more frequent. Yet, treating these patients remains a...
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