Microorganisms, Vol. 8, Pages 780: Phage Display Detection of Mimotopes that are Shared Epitopes of Clinically and Epidemiologically Relevant Enterobacteria Microorganisms doi: 10.3390/microorganisms8050780 Authors: Armando Navarro Delia Licona-Moreno Alejandro Monsalvo-Reyes Ulises Hernández-Chiñas Carlos A. Eslava-Campos Background: Escherichia coli and Salmonella are etiologic agents of intestinal infections. A previous study showed the presence of shared epitopes between...
Microorganisms, Vol. 8, Pages 781: Evaluation of Product Distribution in Chemostat and Batch Fermentation in Lactic Acid-Producing Komagataella phaffii Strains Utilizing Glycerol as Substrate Microorganisms doi: 10.3390/microorganisms8050781 Authors: Tamires Moreira Melo Pontes Procópio Cunha Eliodório Paes Basso Parachin Lactic acid is the monomeric unit of polylactide (PLA), a bioplastic widely used in the packaging, automotive, food, and pharmaceutical...
Microorganisms, Vol. 8, Pages 779: Pathophysiology of Hyperechogenic Bowel in Congenitally Human Cytomegalovirus Infected Fetuses Microorganisms doi: 10.3390/microorganisms8050779 Authors: Liliana Gabrielli Maria P. Bonasoni Angela Chiereghin Giulia Piccirilli Eva C. Borgatti Giuliana Simonazzi Nunzio C. M. Salfi Ione Tamagnini Tiziana Lazzarotto Hyperechogenic bowel (HB) is a nonspecific ultrasound finding that can be associated with human cytomegalovirus (CMV)...
Σήμανση της παραπάνω ενότητας ως αναγνωσμένης
Molbank, Vol. 2020, Article M1138: 9,10-Bis[(4-(2-hydroxyethyl)piperazine-1-yl)prop-2-yne-1-yl]anthracene: Synthesis and G-quadruplex Selectivity Molbank doi: 10.3390/M1138 Authors: Giovanni Ribaudo Alberto Ongaro Erika Oselladore Giuseppe Zagotto Maurizio Memo Alessandra Gianoncelli G-quadruplex DNA is the target of several natural and synthetic small molecules with antiproliferative and antiviral activity. We here report the synthesis through Sonogashira reaction and...
Σήμανση της παραπάνω ενότητας ως αναγνωσμένης
Molecules, Vol. 25, Pages 2449: Influence of Harvest Time and Malaxation Conditions on the Concentration of Individual Phenols in Extra Virgin Olive Oil Related to Its Healthy Properties Molecules doi: 10.3390/molecules25102449 Authors: Panagiotis Diamantakos Triada Giannara Maria Skarkou Eleni Melliou Prokopios Magiatis The phenolic fraction of the extra virgin olive oil (EVOO) has been studied over the past two decades because of its important health protective properties....
Molecules, Vol. 25, Pages 2446: Polymers and Plastics Modified Electrodes for Biosensors: A Review Molecules doi: 10.3390/molecules25102446 Authors: Sonia Lanzalaco Brenda G. Molina Polymer materials offer several advantages as supports of biosensing platforms in terms of flexibility, weight, conformability, portability, cost, disposability and scope for integration. The present study reviews the field of electrochemical biosensors fabricated on modified plastics and polymers, focusing...
Molecules, Vol. 25, Pages 2447: Climate and Processing Effects on Tea (Camellia sinensis L. Kuntze) Metabolome: Accurate Profiling and Fingerprinting by Comprehensive Two-Dimensional Gas Chromatography/Time-of-Flight Mass Spectrometry Molecules doi: 10.3390/molecules25102447 Authors: Federico Stilo Giulia Tredici Carlo Bicchi Albert Robbat Joshua Morimoto Chiara Cordero This study applied an untargeted–targeted (UT) fingerprinting approach, based on comprehensive...
Molecules, Vol. 25, Pages 2445: Dilute-and-Shoot HPLC-UV Method for Determination of Urinary Creatinine as a Normalization Tool in Mycotoxin Biomonitoring in Pigs Molecules doi: 10.3390/molecules25102445 Authors: Agnieszka Tkaczyk Piotr Jedziniak A simple, rapid, and accurate HPLC-UV method was developed for the determination of creatinine in pig urine. Usually, it is determined in urine in biomonitoring of xenobiotics to correct for variations in dilutions of urine samples. The colorimetric...
Molecules, Vol. 25, Pages 2448: Second-Generation Androgen Receptor Antagonists as Hormonal Therapeutics for Three Forms of Prostate Cancer Molecules doi: 10.3390/molecules25102448 Authors: Pravien Rajaram Alyssa Rivera Kevin Muthima Nicholas Olveda Hubert Muchalski Qiao-Hong Chen Enzalutamide is the first second-generation nonsteroidal androgen receptor (AR) antagonist with a strong binding affinity to AR. Most significantly, enzalutamide can prolong not only overall...
Molecules, Vol. 25, Pages 2444: Anti-aggregation Effects of Phenolic Compounds on α-synuclein Molecules doi: 10.3390/molecules25102444 Authors: Kenjiro Ono Mayumi Tsuji Tritia R. Yamasaki Giulio M. Pasinetti The aggregation and deposition of α-synuclein (αS) are major pathologic features of Parkinson’s disease, dementia with Lewy bodies, and other α-synucleinopathies. The propagation of αS pathology in the brain plays a key role...
Molecules, Vol. 25, Pages 2443: Study on Different Water-Based Binders for Li4Ti5O12 Electrodes Molecules doi: 10.3390/molecules25102443 Authors: Christina Toigo Catia Arbizzani Karl-Heinz Pettinger Maurizio Biso In this study, Li4Ti5O12 (LTO) electrodes with different types of water-soluble binders are successfully coated upon aluminum foil. Electrodes containing solely sodium alginate (SA) as a binder or a mixed PVDF/carboxymethyl cellulose (CMC) binder show the most stable...
Molecules, Vol. 25, Pages 2442: Cross-Linked Microencapsulation of CO2 Supercritical Extracted Oleoresins from Sea Buckthorn: Evidence of Targeted Functionality and Stability Molecules doi: 10.3390/molecules25102442 Authors: Corina Neagu Liliana Mihalcea Elena Enachi Vasilica Barbu Daniela Borda Gabriela Elena Bahrim Nicoleta Stănciuc Oleoresin supercritical extracts from sea buckthorn were microencapsulated in whey proteins isolate and casein, in two states: native...
Molecules, Vol. 25, Pages 2440: Co-Occurrence of Moniliformin and Regulated Fusarium Toxins in Maize and Wheat Grown in Italy Molecules doi: 10.3390/molecules25102440 Authors: Terenzio Bertuzzi Paola Giorni Silvia Rastelli Patrizia Vaccino Chiara Lanzanova Sabrina Locatelli The co-occurrence of moniliformin (MON), fumonisins (FBs), and deoxynivalenol (DON) was evaluated in maize, durum, and common wheat grown in different experimental fields located in several Italian...
Molecules, Vol. 25, Pages 2441: Effects of Intra- and Interchain Interactions on Exciton Dynamics of PTB7 Revealed by Model Oligomers Molecules doi: 10.3390/molecules25102441 Authors: Thomas J. Fauvell Zhengxu Cai Matthew S. Kirschner Waleed Helweh Pyosang Kim Tianyue Zheng Richard D. Schaller Luping Yu Lin X. Chen Recent studies have shown that molecular aggregation structures in precursor solutions of organic photovoltaic (OPV) polymers have substantial influence...
Molecules, Vol. 25, Pages 2438: 3D Micro/Nanopatterning of a Vinylferrocene Copolymer Molecules doi: 10.3390/molecules25102438 Authors: Dennis Löber Subhayan Dey Burhan Kaban Fabian Roesler Martin Maurer Hartmut Hillmer Rudolf Pietschnig In nanoimprint lithography (NIL), a pattern is created by mechanical deformation of an imprint resist via embossing with a stamp, where the adhesion behavior during the filling of the imprint stamp and its subsequent detachment may...
Molecules, Vol. 25, Pages 2439: The Positive Side of the Alzheimer’s Disease Amyloid Cross-Interactions: The Case of the Aβ 1-42 Peptide with Tau, TTR, CysC, and ApoA1 Molecules doi: 10.3390/molecules25102439 Authors: Ciccone Shi di Lorenzo Van Baelen Tonali Alzheimer’s disease (AD) represents a progressive amyloidogenic disorder whose advancement is widely recognized to be connected to amyloid-β peptides and Tau aggregation. However, several other...
Molecules, Vol. 25, Pages 2437: Stereochemistry of Simple Molecules inside Nanotubes and Fullerenes: Unusual Behavior of Usual Systems Molecules doi: 10.3390/molecules25102437 Authors: Valerij Kuznetsov Over the past three decades, carbon nanotubes and fullerenes have become remarkable objects for starting the implementation of new models and technologies in different branches of science. To a great extent, this is defined by the unique electronic and spatial properties of nanocavities...
Molecules, Vol. 25, Pages 2436: Sphingosine 1-Phosphate Signaling and Metabolism in Chemoprevention and Chemoresistance in Colon Cancer Molecules doi: 10.3390/molecules25102436 Authors: Petra Grbčić Mirela Sedić Colorectal carcinoma (CRC) is the leading cause of cancer-related deaths worldwide. Despite advances in prevention and treatment modalities for CRC, rapidly developing resistance to chemotherapy limits its effectiveness. For that reason, it is important to better understand...
Molecules, Vol. 25, Pages 2435: Thermotropic Liquid-Crystalline and Light-Emitting Properties of Bis(4-aalkoxyphenyl) Viologen Bis(triflimide) Salts Molecules doi: 10.3390/molecules25102435 Authors: Pradip K. Bhowmik Muhammed Kareem M. Al-Karawi Shane T. Killarney Erenz J. Dizon Anthony Chang Jongin Kim Si L. Chen Ronald Carlo G. Principe Andy Ho Haesook Han Hari D. Mandal Raymond G. Cortez Bryan Gutierrez Klarissa Mendez Lewis Sharpnack Deña M....
Molecules, Vol. 25, Pages 2433: Synthesis, Characterization and Bioassay of Novel Substituted 1-(3-(1,3-Thiazol-2-yl)phenyl)-5-oxopyrrolidines Molecules doi: 10.3390/molecules25102433 Authors: Birutė Sapijanskaitė-Banevič Božena Šovkovaja Rita Vaickelionienė Jūratė Šiugždaitė Eglė Mickevičiūtė Thiazole derivatives attract the attention of scientists both in the field of organic synthesis and bioactivity research due to their high biological activity. In the present study,...
Molecules, Vol. 25, Pages 2432: Chemical Composition and Determination of the Antibacterial Activity of Essential Oils in Liquid and Vapor Phases Extracted from Two Different Southeast Asian Herbs—Houttuynia cordata (Saururaceae) and Persicaria odorata (Polygonaceae) Molecules doi: 10.3390/molecules25102432 Authors: Kristýna Řebíčková Tomáš Bajer David Šilha Markéta Houdková Karel Ventura Petra Bajerová Essential oils obtained via the hydrodistillation of two Asian herbs...
Molecules, Vol. 25, Pages 2431: Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria Molecules doi: 10.3390/molecules25102431 Authors: Zhijun Zhuang Dawei Wan Jun Ding Shijie He Qian Zhang Xiaomei Wang Ying Yuan Yu Lu Charles Z. Ding Anthony Simon Lynch Anna M. Upton Christopher B. Cooper William A. Denny Zhenkun Ma The introductions of the bicyclic 4-nitroimidazole and the oxazolidinone classes of antimicrobial...
Molecules, Vol. 25, Pages 2430: Syntheses and Reactions of Pyrroline, Piperidine Nitroxide Phosphonates Molecules doi: 10.3390/molecules25102430 Authors: Mostafa Isbera Balázs Bognár József Jekő Cecilia Sár Kálmán Hideg Tamás Kálai Organophosphorus compounds occupy a significant position among the plethora of organic compounds, but a limited number of paramagnetic phosphorus compounds have been reported, including paramagnetic phosphonates. This paper describes the syntheses...
Molecules, Vol. 25, Pages 2434: Inhibitory Effects of AF-343, a Mixture of Cassia tora L., Ulmus pumila L., and Taraxacum officinale, on Compound 48/80-Mediated Allergic Responses in RBL-2H3 Cells Molecules doi: 10.3390/molecules25102434 Authors: Eun Kyeong Lee Jeongah Song Youjin Seo Eun Mi Koh Seon-Hee Kim Kyung Jin Jung The purpose of this study was to determine the antiallergic effects of AF-343, a mixture of natural plant extracts from Cassia tora L., Ulmus pumila...
Molecules, Vol. 25, Pages 2428: Structural and Photophysical Properties of 2,1,3-Benzothiadiazole-Based Phosph(III)azane and Its Complexes Molecules doi: 10.3390/molecules25102428 Authors: Radmir Khisamov Taisiya Sukhikh Denis Bashirov Alexey Ryadun Sergey Konchenko Here we describe the synthesis of a novel N,N’-bis(2,1,3-benzothiadiazol-4-yl)-1-phenylphosphanediamine (H2L) and its zinc (II) and copper (I) coordination compounds [Zn2L2]·nC7H8 (1·nC7H8),...
Molecules, Vol. 25, Pages 2427: Does NLRP3 Inflammasome and Aryl Hydrocarbon Receptor Play an Interlinked Role in Bowel Inflammation and Colitis-Associated Colorectal Cancer? Molecules doi: 10.3390/molecules25102427 Authors: Ivan Qi Han Ngui Agampodi Promoda Perera Rajaraman Eri Inflammation is a hallmark in many forms of cancer; with colitis-associated colorectal cancer (CAC) being a progressive intestinal inflammation due to inflammatory bowel disease (IBD). While this is an...
Molecules, Vol. 25, Pages 2429: Bioactive Compounds in Fermented Sausages Prepared from Beef and Fallow Deer Meat with Acid Whey Addition Molecules doi: 10.3390/molecules25102429 Authors: Anna D. Kononiuk Małgorzata Karwowska The present study examined the effect of the type of meat (beef and fallow deer) and the addition of freeze-dried acid whey on nutritional values and the content of bioactive compounds (peptides, L-carnitine, glutathione, and conjugated linoleic acid (CLA)) in...
Molecules, Vol. 25, Pages 2425: Covalent Organic Frameworks: A Promising Materials Platform for Photocatalytic CO2 Reductions Molecules doi: 10.3390/molecules25102425 Authors: Jundan Li Dongni Zhao Jiangqun Liu Anan Liu Dongge Ma Covalent organic frameworks (COFs) are a kind of porous crystalline polymeric material. They are constructed by organic module units connected with strong covalent bonds extending in two or three dimensions. COFs possess the advantages of low-density,...
Molecules, Vol. 25, Pages 2424: Potential Therapeutic Targeting of Coronavirus Spike Glycoprotein Priming Molecules doi: 10.3390/molecules25102424 Authors: Elisa Barile Carlo Baggio Luca Gambini Sergey A. Shiryaev Alex Y. Strongin and Maurizio Pellecchia Processing of certain viral proteins and bacterial toxins by host serine proteases is a frequent and critical step in virulence. The coronavirus spike glycoprotein contains three (S1, S2, and S2′) cleavage sites...
Molecules, Vol. 25, Pages 2423: Nutrient and Sensory Metabolites Profiling of Averrhoa Carambola L. (Starfruit) in the Context of Its Origin and Ripening Stage by GC/MS and Chemometric Analysis Molecules doi: 10.3390/molecules25102423 Authors: Nehal S. Ramadan Ludger A. Wessjohann Andrei Mocan Dan C Vodnar Nabil H. El-Sayed Sayed A. El-Toumy Doha Abdou Mohamed Zeinab Abdel Aziz Anja Ehrlich Mohamed A. Farag Averrhoa carambola L. is a tropical tree with edible...
Molecules, Vol. 25, Pages 2426: Polish Propolis—Chemical Composition and Biological Effects in Tongue Cancer Cells and Macrophages Molecules doi: 10.3390/molecules25102426 Authors: Joanna Wezgowiec Anna Wieczynska Wlodzimierz Wieckiewicz Julita Kulbacka Jolanta Saczko Natalia Pachura Mieszko Wieckiewicz Roman Gancarz Kazimiera A. Wilk The purpose of this study was to compare the chemical composition and biological properties of Polish propolis. Ethanol, ethanol-hexane,...
Molecules, Vol. 25, Pages 2421: Chemical Diversity of Bastard Balm (Melittis melisophyllum L.) as Affected by Plant Development Molecules doi: 10.3390/molecules25102421 Authors: Izabela Szymborska-Sandhu Jarosław L. Przybył Olga Kosakowska Katarzyna Bączek Zenon Węglarz The phytochemical diversity of Melittis melissophyllum was investigated in terms of seasonal changes and age of plants including plant organs diversity. The content of phenolics, namely: coumarin; 3,4-dihydroxycoumarin;...
Molecules, Vol. 25, Pages 2422: Phytochemical Analysis, Network Pharmacology and in Silico Investigations on Anacamptis pyramidalis Tuber Extracts Molecules doi: 10.3390/molecules25102422 Authors: Mohamad Fawzi Mahomoodally Marie Carene Nancy Picot-Allain Gokhan Zengin Eulogio J. Llorent-Martínez Hassan H. Abdullah Gunes Ak Ismail Senkardes Annalisa Chiavaroli Luigi Menghini Lucia Recinella Luigi Brunetti Sheila Leone Giustino Orlando Claudio Ferrante...
Molecules, Vol. 25, Pages 2418: A High-Throughput Screening System Based on Droplet Microfluidics for Glucose Oxidase Gene Libraries Molecules doi: 10.3390/molecules25102418 Authors: Radivoje Prodanović W. Lloyd Ung Karla Ilić Đurđić Rainer Fischer David A. Weitz Raluca Ostafe Glucose oxidase (GOx) is an important industrial enzyme that can be optimized for specific applications by mutagenesis and activity-based screening. To increase the efficiency of this approach, we...
Molecules, Vol. 25, Pages 2420: Selenonium Ylides: Syntheses, Structural Aspects, and Synthetic Applications Molecules doi: 10.3390/molecules25102420 Authors: Józef Drabowicz Aneta Rzewnicka Remigiusz Żurawiński The goals of this mini review constitute a) a presentation of the synthetic protocols applied to the preparation of achiral and non-racemic selenonium ylides; b) discussion of their basic structural features, including their optical activity; and c) a description of their...
Molecules, Vol. 25, Pages 2417: Mitochondrial SLC25 Carriers: Novel Targets for Cancer Therapy Molecules doi: 10.3390/molecules25102417 Authors: Luc Rochette Alexandre Meloux Marianne Zeller Gabriel Malka Yves Cottin Catherine Vergely The transfer of metabolites through the mitochondrial membranes is a vital process that is highly controlled and regulated by the inner membrane. A variety of metabolites, nucleotides, and cofactors are transported across the inner mitochondrial...
Molecules, Vol. 25, Pages 2419: Optical Properties of Composites Based on Graphene Oxide and Polystyrene Molecules doi: 10.3390/molecules25102419 Authors: Malvina Stroe Mirela Cristea Elena Matei Andrei Galatanu Liviu C. Cotet Lucian C. Pop Monica Baia Virginia Danciu Ion Anghel Lucian Baia Mihaela A. Baibarac In this work, new optical properties of composites based on polystyrene (PS) microspheres and graphene oxide (GO) are reported. The radical polymerization...
Molecules, Vol. 25, Pages 2416: Ozonation as a Method of Abiotic Elicitation Improving the Health-Promoting Properties of Plant Products—A Review Molecules doi: 10.3390/molecules25102416 Authors: Monika Sachadyn-Król Sofia Agriopoulou In this review, the primary objective was to systematize knowledge about the possibility of improving the health-promoting properties of raw plant products, defined as an increase in the content of bioactive compounds, by using ozone. The greatest attention...
Molecules, Vol. 25, Pages 2415: Silymarin and Derivatives: From Biosynthesis to Health Benefits Molecules doi: 10.3390/molecules25102415 Authors: Dominique Delmas The past decade has been marked by an intense scientific interest in the use of compounds or micronutrients of natural origin and their potential effects on human health, both from researchers and industry [...]
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