Κυριακή 24 Μαΐου 2020


Reconstruction of Perineal Defects: A Comparison of the Myocutaneous Gracilis and the Gluteal Fold Flap in Interdisciplinary Anorectal Tumor Resection.
Reconstruction of Perineal Defects: A Comparison of the Myocutaneous Gracilis and the Gluteal Fold Flap in Interdisciplinary Anorectal Tumor Resection. Front Oncol. 2020;10:668 Authors: Thiele JR, Weber J, Neeff HP, Manegold P, Fichtner-Feigl S, Stark GB, Eisenhardt SU Abstract Introduction: Resection of anorectal malignancies may result in extensive perineal/pelvic defects that require an interdisciplinary surgical approach involving reconstructive...
pubmed: "front oncol"[jour]
Fri May 22, 2020 13:40
MiR-200b Inhibits Tumor Growth and Chemoresistance via Targeting p70S6K1 in Lung Cancer.
MiR-200b Inhibits Tumor Growth and Chemoresistance via Targeting p70S6K1 in Lung Cancer. Front Oncol. 2020;10:643 Authors: Jin HF, Wang JF, Song TT, Zhang J, Wang L Abstract Downregulation of microRNA-200b (miR-200b) has been identified in a range of cancers, yet the specific mechanisms whereby it influences lung cancer growth require further exploration. We determined that lung cancer patient tumor samples exhibit decreased miR-200b expression, and...
pubmed: "front oncol"[jour]
Fri May 22, 2020 13:40
Long Non-coding RNA LINC02195 as a Regulator of MHC I Molecules and Favorable Prognostic Marker for Head and Neck Squamous Cell Carcinoma.
Long Non-coding RNA LINC02195 as a Regulator of MHC I Molecules and Favorable Prognostic Marker for Head and Neck Squamous Cell Carcinoma. Front Oncol. 2020;10:615 Authors: Li H, Xiong HG, Xiao Y, Yang QC, Yang SC, Tang HC, Zhang WF, Sun ZJ Abstract The loss of major histocompatibility complex class I (MHC I) molecules is an important mechanism by which cancer cells escape immunosurveillance in head and neck squamous cell carcinoma (HNSCC). Several long...
pubmed: "front oncol"[jour]
Fri May 22, 2020 13:40
MTA1 Promotes Hepatocellular Carcinoma Progression by Downregulation of DNA-PK-Mediated H1.2T146 Phosphorylation.
MTA1 Promotes Hepatocellular Carcinoma Progression by Downregulation of DNA-PK-Mediated H1.2T146 Phosphorylation. Front Oncol. 2020;10:567 Authors: Li YH, Zhong M, Zang HL, Tian XF Abstract Global incidence and mortality associated with hepatocellular carcinoma (HCC) is steadily increasing. Metastasis-associated 1 (MTA1) can induce tumorigenesis and metastatic progression in HCC. However, the mechanistic details of MTA1-mediated regulation of HCC has...
pubmed: "front oncol"[jour]
Fri May 22, 2020 13:40
Fighting cancer in coronavirus disease era: organization of work in medical oncology departments in Emilia Romagna region of Italy.
Fighting cancer in coronavirus disease era: organization of work in medical oncology departments in Emilia Romagna region of Italy. Future Oncol. 2020 May 21;: Authors: Brandes AA, Ardizzoni A, Artioli F, Cappuzzo F, Cavanna L, Frassineti GL, Frassoldati A, Leonardi F, Longo G, Maestri A, Tassinari D, Franceschi E, Nunno VD, Pinto C Abstract Aim: To assess which and when measures were applied to reduce coronavirus disease (COVID-19) spreads have been...
Future Oncology.
Fri May 22, 2020 13:30
Pulmonary nodules precision localization techniques.
Pulmonary nodules precision localization techniques. Future Oncol. 2020 May 21;: Authors: Nardini M, Dunning J Abstract The advent of helical high-resolution CT scanners, the application of screening programs and the follow-up of patient with oncological history, led to an increasing number of diagnosis of small pulmonary nodule (less than 10 mm in maximum diameter), partially solid nodule or completely ground glass ones. Their management is controversial....
Future Oncology.
Fri May 22, 2020 13:30
Impact of Meal Frequency on Anthropometric Outcomes: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
Impact of Meal Frequency on Anthropometric Outcomes: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Adv Nutr. 2020 May 21;: Authors: Schwingshackl L, Nitschke K, Zähringer J, Bischoff K, Lohner S, Torbahn G, Schlesinger S, Schmucker C, Meerpohl JJ Abstract The relation between meal frequency and measures of obesity is inconclusive. Therefore, this systematic review and network meta-analysis (NMA) set out to compare the...
pubmed: "adv nutr"[jour]
Fri May 22, 2020 13:26
Primary orthostatic tremor in mandible: A rare case report.
Primary orthostatic tremor in mandible: A rare case report. Indian J Dent Res. 2020 Mar-Apr;31(2):315-317 Authors: Kosminsky M, Grossmann E, Poluha RL Abstract Primary orthostatic tremor (POT) is a rare movement disorder of unknown pathophysiology, characterized by fast tremor affecting a specific part of the body. The present paper reports a case of POT in mandible, discussing the approach and management. A 37-year-old male patient complained of involuntary...
Jaw Tremor
Fri May 22, 2020 13:22
Over the Horizon: The Present and Future of Endovascular Neural Recording and Stimulation.
Over the Horizon: The Present and Future of Endovascular Neural Recording and Stimulation. Front Neurosci. 2020;14:432 Authors: Fan JZ, Lopez-Rivera V, Sheth SA Abstract The past decade has witnessed an explosion in applications for neural recording and stimulation in the treatment of clinical disorders. Neuromodulatory approaches are now a mainstay of care for essential tremor and Parkinson's disease, and are expanding rapidly into a wide range of other...
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
The Role of NMDA Receptors in the Effect of Purinergic P2X7 Receptor on Spontaneous Seizure Activity in WAG/Rij Rats With Genetic Absence Epilepsy.
The Role of NMDA Receptors in the Effect of Purinergic P2X7 Receptor on Spontaneous Seizure Activity in WAG/Rij Rats With Genetic Absence Epilepsy. Front Neurosci. 2020;14:414 Authors: Doǧan E, Aygün H, Arslan G, Rzayev E, Avcı B, Ayyıldız M, Ağar E Abstract P2X7 receptors (P2X7Rs) are ATP sensitive cation channels and have been shown to be effective in various epilepsy models. Absence epilepsy is a type of idiopathic, generalized, non-convulsive epilepsy....
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
Deep Learning Provides Exceptional Accuracy to ECoG-Based Functional Language Mapping for Epilepsy Surgery.
Deep Learning Provides Exceptional Accuracy to ECoG-Based Functional Language Mapping for Epilepsy Surgery. Front Neurosci. 2020;14:409 Authors: RaviPrakash H, Korostenskaja M, Castillo EM, Lee KH, Salinas CM, Baumgartner J, Anwar SM, Spampinato C, Bagci U Abstract The success of surgical resection in epilepsy patients depends on preserving functionally critical brain regions, while removing pathological tissues. Being the gold standard, electro-cortical...
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
Harmonization of Brain Diffusion MRI: Concepts and Methods.
Harmonization of Brain Diffusion MRI: Concepts and Methods. Front Neurosci. 2020;14:396 Authors: Pinto MS, Paolella R, Billiet T, Van Dyck P, Guns PJ, Jeurissen B, Ribbens A, den Dekker AJ, Sijbers J Abstract MRI diffusion data suffers from significant inter- and intra-site variability, which hinders multi-site and/or longitudinal diffusion studies. This variability may arise from a range of factors, such as hardware, reconstruction algorithms and acquisition...
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
Involvement of Secretin in the Control of Cell Survival and Synaptic Plasticity in the Central Nervous System.
Involvement of Secretin in the Control of Cell Survival and Synaptic Plasticity in the Central Nervous System. Front Neurosci. 2020;14:387 Authors: Wang L, Zhang L Abstract With emerging evidence showing a wide distribution of secretin (SCT) and its receptor (SCTR) in the central nervous system (CNS), the putative neuropeptide role of SCT has become more appreciated since the disruption of SCT/SCTR axis affects various neural functions. This mini review...
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
Dietary Fiber Is Inversely Associated With Depressive Symptoms in Premenopausal Women.
Dietary Fiber Is Inversely Associated With Depressive Symptoms in Premenopausal Women. Front Neurosci. 2020;14:373 Authors: Li D, Tong Y, Li Y Abstract Background: An inverse association between dietary fiber intake and depressive symptoms was reported in the general population, but this association is unstudied in midlife women. This study was designed to investigate the association of dietary fiber intake with depressive symptoms in midlife women....
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
Myriocin Effect on Tvrm4 Retina, an Autosomal Dominant Pattern of Retinitis Pigmentosa.
Myriocin Effect on Tvrm4 Retina, an Autosomal Dominant Pattern of Retinitis Pigmentosa. Front Neurosci. 2020;14:372 Authors: Piano I, D'Antongiovanni V, Novelli E, Biagioni M, Dei Cas M, Paroni RC, Ghidoni R, Strettoi E, Gargini C Abstract Tvrm4 mice, a model of autosomal dominant retinitis pigmentosa (RP), carry a mutation of Rhodopsin gene that can be activated by brief exposure to very intense light. Here, we test the possibility of an anatomical,...
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
Analyzing Brain Connectivity in the Mutual Regulation of Emotion-Movement Using Bidirectional Granger Causality.
Analyzing Brain Connectivity in the Mutual Regulation of Emotion-Movement Using Bidirectional Granger Causality. Front Neurosci. 2020;14:369 Authors: Li T, Li G, Xue T, Zhang J Abstract Body language and movement are important media of emotional expression. There is an interactive physiological relationship between emotion and movement. Thus, we hypothesize that the emotional cortex interacts with the motor cortex during the mutual regulation of emotion...
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
Bright Light Therapy and Circadian Cycles in Institutionalized Elders.
Bright Light Therapy and Circadian Cycles in Institutionalized Elders. Front Neurosci. 2020;14:359 Authors: Rubiño JA, Gamundí A, Akaarir M, Canellas F, Rial R, Nicolau MC Abstract Background: Bright light therapy has been found to be an efficient method to improve the main parameters of circadian rhythms. However, institutionalized elders may suffer reduced exposure to diurnal light, which may impair their circadian rhythms, cognitive performance, and...
pubmed: frontiers in neurosc...
Fri May 22, 2020 13:10
Autocrine VEGF signalling on M2 macrophages regulates PD-L1 expression for immunomodulation of T cells.
Related ArticlesAutocrine VEGF signalling on M2 macrophages regulates PD-L1 expression for immunomodulation of T cells. J Cell Mol Med. 2019 02;23(2):1257-1267 Authors: Lai YS, Wahyuningtyas R, Aui SP, Chang KT Abstract M2-polarized macrophages, on one hand, can promote tumour vascularization by producing proangiogenic factors, such as vascular endothelial growth factor (VEGF). On the other hand, the expression of VEGF receptors (VEGFR) in this cell...
VEGF/VEGFR inhibitors - Angiogenesis inhibitor
Fri May 22, 2020 13:01
Correction to: Genetic algorithms identify individuals with high risk of severe liver disease caused by schistosomes
In the original article publication, the affiliation of the author Ana Coutinho is incorrect.
Human Genetics
Fri May 22, 2020 03:00
Πολλαπλή Σκλήρυνση: Η εναλλακτική θεραπεία που φέρνει αποτελέσματα
Ο λόγος για την πρακτική του mindfulness, την ενσυνειδητότητα όπως έχει μεταφερθεί στα ελληνικά, που καλλιεργεί την επίγνωση, την προσοχή και την ψυχική δύναμη. Η συγκεκριμένη πρακτική εστιάζει συνήθως στην εξάσκηση της προσοχής, της αναπνοής και του διαλογισμού πάνω στη σχέση του σώματος με την ψυχή. Τη μικρή αυτή πιλοτική μελέτη (θα ακολουθήσει πιο εκτεταμένη), πραγματοποίησε το τμήμα ψυχολογίας του Πανεπιστημίου του Οχάιο και έχει δημοσιευθεί σε δύο επιστημονικά περιοδικά, το Rehabilitation Psychology...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Fri May 22, 2020 08:30
Καρδιαγγειακά νοσήματα: Γιατί η καρδιά προδίδει λιγότερες γυναίκες από ότι άνδρες
Μια εκτενής επιστημονική μελέτη στην οποία συμμετείχαν περισσότεροι από 160.000 άνθρωποι από 21 χώρες υποστηρίζει ότι οι γυναίκες έχουν λιγότερες πιθανότητες από τους άνδρες να νοσήσουν από κάποια καρδιαγγειακή πάθηση και να πεθάνουν από αυτή. Σύμφωνα, μάλιστα, με τη σχετική δημοσίευση στο The Lancet, η έρευνα έδειξε ότι δεν είχε σημασία αν οι γυναίκες είχαν υποστεί καρδιακή προσβολή ή εγκεφαλικό επεισόδιο, σε ποιο μέρος του πλανήτη ζούσαν ή η οικονομική τους κατάσταση. Η μελέτη διεξήχθη από το...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Fri May 22, 2020 08:25
Κορωνοϊός – Σταγονίδια: Πόσο μακριά και πόσο γρήγορα ταξιδεύουν όταν φυσάει
Η αερομεταφερόμενη μετάδοση ιών, όπως ο ιός που προκαλεί το COVID-19, δεν έχει εξηγηθεί πλήρως όσον αφορά τον τρόπο που τα σταγονίδια ταξιδεύουν όταν οι άνθρωποι βήχουν και μέχρι που φτάνουν. Σε επιστημονικό  άρθρο που δημοσιεύθηκε στο Physics of Fluids, οι Talib Dbouk και προφανώς ελληνικής καταγωγής Dimitris Drikakis ανακάλυψαν ότι ακόμη και με μια μικρή αύρα 4 χλμ /ώρα (ταχύτητα ανέμου), το σάλιο ταξιδεύει 6 μέτρα σε 5 δευτερόλεπτα. Το σάλιο είναι ένα σύνθετο υγρό και ταξιδεύει αιωρούμενο σε...
Επιστημονικές Εξελίξεις – ygeiamou | Το αξιόπιστο site για την Υγεία, τη Διατροφή και την Ευεξία
Fri May 22, 2020 08:05
High-Definition Excisional Body Contouring: Mini Lipoabdominoplasty (FIT Mommy) and Enhanced Viability Abdominoplasty
Publication date: July 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 3Author(s): Alfredo E. Hoyos Ariza, Mauricio E. Perez Pachon
Plastic Surgery
Fri May 22, 2020 12:30
Clinics in Plastic Surgery
Publication date: July 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 3Author(s):
Plastic Surgery
Fri May 22, 2020 12:30
Contents
Publication date: July 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 3Author(s):
Plastic Surgery
Fri May 22, 2020 12:30
Contributors
Publication date: July 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 3Author(s):
Plastic Surgery
Fri May 22, 2020 12:30
Copyright
Publication date: July 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 3Author(s):
Plastic Surgery
Fri May 22, 2020 12:30
Abdominoplasty
Publication date: July 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 3Author(s): Alan Matarasso, James E. Zins
Plastic Surgery
Fri May 22, 2020 12:30
The difficult airway in severe facial trauma
Publication date: Available online 21 May 2020Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Danielle Kumpf, Robert Saadi, Jessyka G. Lighthall
Otolaryngology-Head and Neck Surgery
Fri May 22, 2020 12:20
The approach and operative implications for the partially obstructed airway with impending or sudden loss of the airway
Publication date: Available online 21 May 2020Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Joseph C. Park, Alexander T. Hillel
Otolaryngology-Head and Neck Surgery
Fri May 22, 2020 12:20
Continuously controllable photoconductance in freestanding BiFeO<sub>3</sub> by the macroscopic flexoelectric effect
Nature Communications, Published online: 22 May 2020; doi:10.1038/s41467-020-16465-5Previous methods to generate strain gradient and flexoelectricity are limited to a localized effect or cannot be tuned continuously. Here, the authors achieve macroscale continuously controllable strain gradient in freestanding ferroelectric thin film. Multilevel photoconductance in BiFeO3 films can be achieved by coupling between the flexoelectric and ferroelectric photovoltaic effect.
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00
Integrated redox-active reagents for photoinduced regio- and stereoselective fluorocarboborylation
Nature Communications, Published online: 22 May 2020; doi:10.1038/s41467-020-16477-1The synthesis of vinylboronates and alkylboronates often suffers from step-tedious and poorly stereoselective procedures. Here, the authors report a bench-stable redox-active reagent for the radical difunctionalization of alkenes and alkynes affording fluorine-containing vinylboronates and alkylboronates.
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00
Bringing nuclear materials discovery and qualification into the 21<sup>st</sup> century
Nature Communications, Published online: 22 May 2020; doi:10.1038/s41467-020-16406-2Time horizons for nuclear materials development and qualification must be shortened to realize future nuclear energy concepts. Inspired by the Materials Genome Initiative, we present an integrated approach to materials discovery and qualification to insert new materials into service.
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00
Fracture toughness of a metal–organic framework glass
Nature Communications, Published online: 22 May 2020; doi:10.1038/s41467-020-16382-7Metal-organic framework glasses are gaining interest, but large samples are difficult to fabricate and mechanical properties are not well understood. Here, the authors use experiments and simulations to assess fracture toughness and flexural strength of a zeolitic imidazolate framework glass.
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00
KAT3-dependent acetylation of cell type-specific genes maintains neuronal identity in the adult mouse brain
Nature Communications, Published online: 22 May 2020; doi:10.1038/s41467-020-16246-0Neuronal identity maintenance is highly regulated. Here, the authors showed that CBP and p300 safeguard neuronal identity through histone acetylation at promoters and enhancers of neuronal specific genes. The loss of both CBP and p300 impairs gene expression, circuit activity, and behavior in mice.
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00
Extreme active matter at high densities
Nature Communications, Published online: 22 May 2020; doi:10.1038/s41467-020-16130-xWhile active matter exhibits unusual dynamics at low density, high density behavior has not been explored. Mandal et al. show that extreme dense active matter, shows a rich spectrum of behaviour from intermittent plastic bursts and turbulence, to glassy states and jamming in the limit of infinite persistence time.
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00
A cysteine selenosulfide redox switch for protein chemical synthesis
Nature Communications, Published online: 22 May 2020; doi:10.1038/s41467-020-16359-6Control of cysteine reactivity is of paramount importance for the synthesis of proteins using native chemical ligation. Here, the authors report a readily cleavable N-selenoethyl group attached to cysteine and apply it to the modular assembly of linear and cyclic polypeptides.
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00
Genome-scale metabolic reconstruction of the symbiosis between a leguminous plant and a nitrogen-fixing bacterium
Nature Communications, Published online: 22 May 2020; doi:10.1038/s41467-020-16484-2The association between leguminous plants and rhizobial bacteria is a paradigmatic example of a symbiosis driven by metabolic exchanges. Here, diCenzo et al. report the reconstruction and modelling of a genome-scale metabolic network of the plant Medicago truncatula nodulated by the bacterium Sinorhizobium meliloti.
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00
Continuously controllable photoconductance in freestanding BiFeO<sub>3</sub> by the macroscopic flexoelectric effect
Nature Communications - current - nature.com science feeds
Fri May 22, 2020 03:00

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