No abstract available
Tue May 19, 2020 14:06
Background: Central venous obstruction (stenosis or occlusion) is common in patients with renal failure on hemodialysis and may be associated with intracranial hypertension (IH). Causes include vein injury from an endoluminal device, lumen obstruction from a device or thrombus, external vein compression, and high venous flow leading to vein intimal hyperplasia. A combination of high venous flow and central venous obstruction can lead to intracranial venous hypertension, impaired cerebrospinal...
Tue May 19, 2020 14:06
Abstract: The mechanism for stable gaze-holding requires a neural integrator that converts pulse of neural discharge to steady firing rate. The integrator is feedback-dependent, impaired feedback manifests as either “unstable” integration when it is too much or “leaky” when it is too little. The “unstable” integrator is known to cause sinusoidal oscillations of the eyes called pendular nystagmus, whereas the “leaky” integrator causes jerky eye oscillations called gaze-evoked nystagmus. We hypothesized...
Tue May 19, 2020 14:06
No abstract available
Tue May 19, 2020 14:06
Background: Restoration of vision in patients blinded by advanced optic neuropathies requires technologies that can either 1) salvage damaged and prevent further degeneration of retinal ganglion cells (RGCs), or 2) replace lost RGCs. Evidence Acquisition: Review of scientific literature. Results: In this article, we discuss the different barriers to cell-replacement based strategies for optic nerve regeneration and provide an update regarding what progress that has been made to overcome...
Tue May 19, 2020 14:06
Abstract: A 74-year-old man with vasculopathic risk factors presented to the emergency room with a chief complaint of peripheral vision loss resulting from an intracranial hemorrhage in his right parietal and occipital lobes. Urgent craniotomy and ventriculostomy led to a stable clinical condition with subsequent development of a crossed quadrant homonymous hemianopsia (checkerboard visual field) due to a new right parieto-occipital infarct superimposed on a prior left occipital infarct. This...
Tue May 19, 2020 14:06
Related ArticlesAdvances and challenges in the treatment of primary central nervous system lymphoma. J Cell Physiol. 2020 May 18;: Authors: Yang H, Xun Y, Yang A, Liu F, You H Abstract Primary central nervous system lymphoma (PCNSL), a rare variant of non-Hodgkin's lymphoma, is characterized by distinct biological characteristics and clinical behaviors, and patient prognosis is not satisfactory. The advent of high-dose (HD) methotrexate (HD-MTX) therapy...
Tue May 19, 2020 14:04
Related ArticlesThe P2Y6 receptor signals through Gαq /Ca2+ /PKCα and Gα13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration. J Cell Physiol. 2020 May 18;: Authors: Girard M, Dagenais Bellefeuille S, Eiselt É, Brouillette R, Placet M, Arguin G, Longpré JM, Sarret P, Gendron FP Abstract Cell migration is a ubiquitous process necessary to maintain and restore tissue functions. However, in cancer, cell migration leads...
Tue May 19, 2020 14:04
Related ArticlesReply to Ferreira et al. Adv Nutr. 2020 May 01;11(3):737-738 Authors: Craddock JC, Neale EP, Peoples GE, Probst YC PMID: 32419022 [PubMed - in process]
Tue May 19, 2020 14:04
Related ArticlesReply to M. Heidari and S. Rezaei. Adv Nutr. 2020 May 01;11(3):742 Authors: Jung UJ, Kim SR PMID: 32419021 [PubMed - in process]
Tue May 19, 2020 14:04
Related ArticlesReply to JG Dórea. Adv Nutr. 2020 May 01;11(3):740 Authors: Katz DL, Gardner CD PMID: 32419020 [PubMed - in process]
Tue May 19, 2020 14:04
Related ArticlesReply to A Salari-Moghaddam et al. Adv Nutr. 2020 May 01;11(3):743 Authors: Fabiani R, Naldini G, Chiavarini M PMID: 32419019 [PubMed - in process]
Tue May 19, 2020 14:04
Related Articles(Re)search Filter Bubble Effect-An Issue Still Unfairly Neglected. Adv Nutr. 2020 May 01;11(3):744 Authors: Ćurković M, Košec A PMID: 32419018 [PubMed - in process]
Tue May 19, 2020 14:04
Related ArticlesLetter to the Editor on "Perspective: Therapeutic Potential of Flavonoids as Alternative Medicines in Epilepsy". Adv Nutr. 2020 May 01;11(3):741 Authors: Heidari M, Rezaei S PMID: 32419017 [PubMed - in process]
Tue May 19, 2020 14:04
Related ArticlesWhy Not Talk about the Harms of Meat Consumption? Adv Nutr. 2020 May 01;11(3):736 Authors: Ferreira EP, Acosta-Navarro JC, Antoniazzi L PMID: 32419016 [PubMed - in process]
Tue May 19, 2020 14:04
Related ArticlesComments on "The Public Health Case for Modernizing the Definition of Protein Quality". Adv Nutr. 2020 May 01;11(3):739 Authors: Dórea JG PMID: 32419015 [PubMed - in process]
Tue May 19, 2020 14:04
Abstract Temperature determines the rates of all biochemical and biophysical processes, and is also believed to be a key driver of macroevolutionary patterns. It is suggested that physiological constraints at low temperatures may diminish the fitness advantages of otherwise beneficial mutations; by contrast, relatively high, benign, temperatures allow beneficial mutations to efficiently show their phenotypic effects. To experimentally test this ‘mutational effects’ mechanism, we examined the fitness...
Mon May 18, 2020 21:35
Related ArticlesTargeting Different Pathways Using Novel Combination Therapy in Triple Negative Breast Cancer. Curr Cancer Drug Targets. 2020 May 17;: Authors: Mir M, Khan H, Mehraj U, Nisar S, Bhat B, Wani N Abstract Triple negative breast cancer (TNBC) is one of the most aggressive subtype of breast cancer accounting for 15-20% of cases and is defined by the lack of hormonal receptors viz., estrogen receptor (ER), progesterone receptor (PR) and expression...
Tue May 19, 2020 13:58
Related ArticlesCYP1A1 and CYP2D6 Polymorphisms and Susceptibility to Chronic Myelocytic Leukaemia. Curr Cancer Drug Targets. 2020 May 17;: Authors: Idris HM, Khalil HB, Mills J, Elderdery AY Abstract BACKGROUND: CYP1A1 and CYP2D6 are both xenobiotic metabolizing enzymes belonging to the CYP450 enzyme family. Polymorphisms in these genes vary between individuals, resulting in dissimilar patterns of susceptibility to the effects of carcinogenic substances...
Tue May 19, 2020 13:58
Related ArticlesFLT3 Inhibition in Acute Myeloid Leukaemia - Current Knowledge and Future Prospects. Curr Cancer Drug Targets. 2020 May 17;: Authors: Hogan FL, Williams V, Knapper S Abstract Activating mutations of FMS-like tyrosine kinase 3 (FLT3) are present in 30% of acute myeloid leukaemia (AML) patients at diagnosis and confer an adverse clinical prognosis. Mutated FLT3 has emerged as a viable therapeutic target and a number of FLT3-directed tyrosine...
Tue May 19, 2020 13:58
Publication date: Available online 19 May 2020Source: Allergology InternationalAuthor(s): Toshiyuki Koya, Yosuke Kimura, Masachika Hayashi, Takashi Hasegawa, Toshiaki Kikuchi
Tue May 19, 2020 13:56
Publication date: Available online 18 May 2020Source: Allergology InternationalAuthor(s): Miki Kume, Yukinobu Nakagawa, Eiji Kiyohara, Noriko Arase, Mari Wataya-Kaneda, Moto Yaga, Masahiro Yanagawa, Manabu Fujimoto
Tue May 19, 2020 13:56
Related ArticlesSialoscintigraphy - Shopworn or Bestselling? A Traditional Procedure with New Prominent Role in Theranostics and Immuno-Oncology. Nuklearmedizin. 2020 May 18;: Authors: Kreppel B, Gaertner FC, Essler M Abstract Sialoscintigraphy has been used in nuclear imaging for almost sixty years. It allows functional assessment and quantification of all large salivary glands. Physiological function of the salivary glands is essential for the preservation...
Tue May 19, 2020 13:56
Related ArticlesRadiation Oncology APM: an introduction and primer for the proposed rule for practices and providers. Pract Radiat Oncol. 2020 May 15;: Authors: Li R, Yashar C, Thaker N, Beriwal S, Glaser S Abstract INTRODUCTION: The Radiation Oncology Alternative Payment Model (RO-APM) is an alternative payment model under which Medicare patients would be reimbursed using an episode-based payment schema rather than the current fee-for-service (FFS)...
Tue May 19, 2020 13:56
Related ArticlesGeographic Distribution of Radiation Oncologists in the United States. Pract Radiat Oncol. 2020 May 15;: Authors: Bates JE, Parekh AD, Chowdhary M, Amdur RJ Abstract BACKGROUND: The geographic distribution of radiation oncologists determines access to care for patients and job opportunities for practicing physicians, yet available data on practicing radiation oncologists are outdated or use large geographic unit definitions precluding...
Tue May 19, 2020 13:56
Related ArticlesLeukocyte telomere length and hTERT genetic polymorphism rs2735940 influence the renal cell carcinoma clinical outcome. Future Oncol. 2020 May 18;: Authors: Morais M, Dias F, Resende T, Nogueira I, Oliveira J, Maurício J, Teixeira AL, Medeiros R Abstract Aim: Analysis of the genetic hTERT-1327 C>T (rs2735940) influence on leukocyte telomere length (LTL) and tumor development, progression and overall survival in renal cell carcinoma...
Tue May 19, 2020 13:56
Related ArticlesHost circulating biomarkers for immune-checkpoint inhibitors: single-agent and combinations. Future Oncol. 2020 May 18;: Authors: Riudavets M, Auclin E, Mezquita L PMID: 32422071 [PubMed - as supplied by publisher]
Tue May 19, 2020 13:56
Related ArticlesRisk factors for developing cardiac toxicities in cancer patients treated with panitumumab combination therapy. Future Oncol. 2020 May 18;: Authors: Qi WX, Zhao S, Chen J Abstract Aim: To evaluate the incidence and risk of cardiac toxicities associated with panitumumab in advanced cancer of Caucasian patients. Materials & methods: The incidence of cardiac toxicity was assessed by simple incidence rates and rates per 100 person-years....
Tue May 19, 2020 13:56
Related ArticlesSalivary duct carcinoma: Updates in histology, cytology, molecular biology, and treatment. Cancer Cytopathol. 2020 May 18;: Authors: Nakaguro M, Tada Y, Faquin WC, Sadow PM, Wirth LJ, Nagao T Abstract Salivary duct carcinoma (SDC) is an aggressive subtype of primary salivary gland carcinoma, often with an advanced stage at presentation and high rates of metastasis and recurrence. It most commonly arises in the parotid gland of older men...
Tue May 19, 2020 13:56
Related ArticlesFrom Theory to Practice: Implementation of Strategies to Reduce Acute Care Visits in Patients With Cancer. Am Soc Clin Oncol Educ Book. 2020 May;40:85-94 Authors: Daly B, Michaelis LC, Sprandio JD, Kapke JT, Narra RK, Malosh E, Zervoudakis A, Holland J, Zablocki M Abstract Patients with cancer frequently seek acute care as a result of complications of their disease and adverse effects of treatment. This acute care comes at high cost to...
Tue May 19, 2020 13:56
Related ArticlesMetastatic propagation of thyroid cancer; organ tropism and major modulators. Future Oncol. 2020 May 18;: Authors: Rajabi S, Shakib H, Dastmalchi R, Danesh-Afrooz A, Karima S, Hedayati M Abstract Thyroid cancer, as the most prevalent endocrine malignancy, comprises nearly 1% of all cancers in the world. The metastatic propagation of thyroid cancer is under the control of a number of modulating processes and factors such as signaling pathways...
Tue May 19, 2020 13:56
Related ArticlesElectrochemotherapy in 3D Ocular Melanoma Spheroids using a Customized Electrode. J Vis Exp. 2020 Apr 21;(158): Authors: Fiorentzis M, Viestenz A, Seitz B, Coupland SE, Heinzelmann J Abstract Electrochemotherapy (ECT) is the combination of transient pore formation following electric pulse application with the administration of cytotoxic drugs, which enhances the cytotoxic effect of the applied agent due to membrane changes. In vitro 3D...
Tue May 19, 2020 13:56
Related ArticlesSerine-227 in the N-terminal kinase domain of RSK2 is a potential therapeutic target for mantle cell lymphoma. Cancer Med. 2020 May 18;: Authors: Matsumura-Kimoto Y, Tsukamoto T, Shimura Y, Chinen Y, Tanba K, Kuwahara-Ota S, Fujibayashi Y, Nishiyama D, Isa R, Yamaguchi J, Kawaji-Kanayama Y, Kobayashi T, Horiike S, Taniwaki M, Kuroda J Abstract RSK2 is a serine/threonine kinase downstream signaling mediator in the RAS/ERK signaling pathway...
Tue May 19, 2020 13:56
Related ArticlesRole of microRNAs in the predisposition to gastrointestinal malignancies. World J Clin Cases. 2020 May 06;8(9):1580-1585 Authors: Baz M, Ibrahim T Abstract MicroRNAs (miRNAs) are highly deregulated in cancer and play a role in the initiation of tumorigenesis. Recently, miRNAs have attracted attention in gastrointestinal (GI) cancers. Single nucleotide polymorphisms (SNPs) could affect the genes involved in each step of miRNA biosynthesis....
Tue May 19, 2020 13:56
Related ArticlesTreatment strategy for patients with relapsed small-cell lung cancer: past, present and future. Transl Lung Cancer Res. 2020 Apr;9(2):172-179 Authors: Wakuda K PMID: 32420056 [PubMed]
Tue May 19, 2020 13:56
Related ArticlesDynamic changes in circulating T follicular helper cell composition predict neutralising antibody responses after yellow fever vaccination. Clin Transl Immunology. 2020 May;9(5):e1129 Authors: Huber JE, Ahlfeld J, Scheck MK, Zaucha M, Witter K, Lehmann L, Karimzadeh H, Pritsch M, Hoelscher M, von Sonnenburg F, Dick A, Barba-Spaeth G, Krug AB, Rothenfußer S, Baumjohann D Abstract Objectives: T follicular helper (Tfh) cells are the principal...
Tue May 19, 2020 13:56
Related ArticlesProfiles of Perceived Social Functioning in Adolescent and Young Adult Survivors of Childhood Cancer. Psychooncology. 2020 May 17;: Authors: Willard VW, Tillery R, Gordon ML, Long A, Phipps S Abstract OBJECTIVES: Social interaction and peer relationships are critical for development, especially for adolescents and young adults (AYA). Cancer treatment may disrupt social functioning and impact quality of life. Prior research into AYA social...
Tue May 19, 2020 13:56
Related ArticlesThe Landmark Series: Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2020 May 17;: Authors: Cloyd JM, Ejaz A, Pawlik TM Abstract INTRODUCTION: Intrahepatic cholangiocarcinoma (ICC) is an aggressive biliary tract cancer (BTC) with distinct anatomic, molecular, and clinical characteristics that distinguishes it from other BTCs. METHODS: In this landmark series review, we highlight the critical studies that have defined the surgical...
Tue May 19, 2020 13:56
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