Cells, Vol. 9, Pages 1145: Identifying the Therapeutic Significance of Mesenchymal Stem Cells Cells doi: 10.3390/cells9051145 Authors: Vineet Mishra Hui-Hsuan Shih Farzana Parveen David Lenzen Etsuro Ito Te-Fu Chan Liang-Yin Ke The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due to their immense potential for immunosuppression and their therapeutic role in immune disorders. MSCs migrate towards inflamed microenvironments, produce...
Wed May 06, 2020 03:00
Cells, Vol. 9, Pages 1144: Integrative Cluster Analysis of Whole Hearts Reveals Proliferative Cardiomyocytes in Adult Mice Cells doi: 10.3390/cells9051144 Authors: Anne-Marie Galow Markus Wolfien Paula Müller Madeleine Bartsch Ronald M. Brunner Andreas Hoeflich Olaf Wolkenhauer Robert David Tom Goldammer The recent development and broad application of sequencing techniques at the single-cell level is generating an unprecedented amount of data. The different techniques...
Wed May 06, 2020 03:00
Cells, Vol. 9, Pages 1143: Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids Cells doi: 10.3390/cells9051143 Authors: Francisco Guillen-Chable Ulises Corona Alejandro Pereira-Santana Andrea Bayona Luis Rodríguez-Zapata Cecilia Aquino Lenka Šebestová Nicolas Vitale Pavel Hozak Enrique Castano Fibrillarin is a highly conserved nucleolar methyltransferase responsible for ribosomal RNA methylation across evolution from...
Wed May 06, 2020 03:00
Cells, Vol. 9, Pages 1141: The Role of Extracellular Vesicles in the Hallmarks of Cancer and Drug Resistance Cells doi: 10.3390/cells9051141 Authors: Cristina P. R. Xavier Hugo R. Caires Mélanie A. G. Barbosa Rui Bergantim José E. Guimarães M. Helena Vasconcelos Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the maintenance of the physiological...
Wed May 06, 2020 03:00
Cells, Vol. 9, Pages 1142: p62 is Negatively Implicated in the TRAF6-BECN1 Signaling Axis for Autophagy Activation and Cancer Progression by Toll-Like Receptor 4 (TLR4) Cells doi: 10.3390/cells9051142 Authors: Mi-Jeong Kim Yoon Min Ji Seon Im Juhee Son Joo Sang Lee Ki-Young Lee Toll-like receptors (TLRs) induce the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and autophagy through the TNF (Tumor necrosis factor) receptor-associated...
Wed May 06, 2020 03:00
Cells, Vol. 9, Pages 1140: Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells Cells doi: 10.3390/cells9051140 Authors: Hannah Jonescheit Hans-Heinrich Oberg Daniel Gonnermann Martin Hermes Vjola Sulaj Christian Peters Dieter Kabelitz Daniela Wesch Background: Pancreatic ductal adenocarcinoma (PDAC) is a malignant gastrointestinal disease. The enzyme indoleamine-2,3-dioxgenase...
Wed May 06, 2020 03:00
Cells, Vol. 9, Pages 1139: RPAP3 C-Terminal Domain: A Conserved Domain for the Assembly of R2TP Co-Chaperone Complexes Cells doi: 10.3390/cells9051139 Authors: Carlos F. Rodríguez Oscar Llorca The Rvb1-Rvb2-Tah1-Pih1 (R2TP) complex is a co-chaperone complex that works together with HSP90 in the activation and assembly of several macromolecular complexes, including RNA polymerase II (Pol II) and complexes of the phosphatidylinositol-3-kinase-like family of kinases (PIKKs), such as...
Wed May 06, 2020 03:00
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