Τετάρτη 13 Μαΐου 2020

The antiatherogenic function of kallistatin and its potential mechanism.
Related ArticlesThe antiatherogenic function of kallistatin and its potential mechanism. Acta Biochim Biophys Sin (Shanghai). 2020 May 11;: Authors: Wang G, Zou J, Yu X, Yin S, Tang C Abstract Atherosclerosis is the pathological basis of most cardiovascular diseases, the leading cause of morbidity and mortality worldwide. Kallistatin, originally discovered in human serum, is a tissue-kallikrein-binding protein and a unique serine proteinase inhibitor....
Angiogenesis inhibitor
1h
[Effective treatment of POEMS syndrome accompanied by plasmacytoma with lenalidomide, dexamethasone, and local irradiation].
Related Articles[Effective treatment of POEMS syndrome accompanied by plasmacytoma with lenalidomide, dexamethasone, and local irradiation]. Rinsho Ketsueki. 2020;61(3):262-267 Authors: Takahashi W, Ichikawa M, Okazaki A, Nakamura F, Arai H, Handa T, Nakamura Y, Nakamura Y, Seo S, Sasaki K, Mitani K Abstract A 70-year-old woman experienced pain in both gastrocnemius muscles, numbness in the toes, and muscle weakness in both the legs that lasted for...
Angiogenesis inhibitor
1h
[Ultra high-risk refractory multiple myeloma with a complex karyotype including t(14;19)].
Related Articles[Ultra high-risk refractory multiple myeloma with a complex karyotype including t(14;19)]. Rinsho Ketsueki. 2020;61(3):240-244 Authors: Aoki G, Sawazaki A, Notsumata K, Ushiogi Y, Okafuji K, Toya D Abstract A 78-year-old man was hospitalized because of rapid progression of chronic renal failure and diagnosed with multiple myeloma (MM) IgG-λ type ISS-III R-ISS-II with complex karyotype including t(14;19). Even after receiving bortezomib-based...
Angiogenesis inhibitor
1h
One drug and two diseases: A case of multidrug-resistant hidradenitis suppurativa and psoriasis treated with apremilast.
Related ArticlesOne drug and two diseases: A case of multidrug-resistant hidradenitis suppurativa and psoriasis treated with apremilast. Dermatol Ther. 2019 11;32(6):e13089 Authors: Lanna C, Mazzilli S, Zangrilli A, Bianchi L, Campione E Abstract Hidradenitis suppurativa and psoriasis are chronic inflammatory skin disorders. The onset of these pathologies is due to the interaction between genetic, environmental, and immunological factors making them...
Angiogenesis inhibitor
1h
Steroid-resistant alopecia totalis in a child successfully treated with oral apremilast and platelet-rich plasma therapy.
Related ArticlesSteroid-resistant alopecia totalis in a child successfully treated with oral apremilast and platelet-rich plasma therapy. Dermatol Ther. 2019 11;32(6):e13082 Authors: Chhabra G, Verma P PMID: 31495982 [PubMed - indexed for MEDLINE]
Angiogenesis inhibitor
1h
A phase Ib study of the combination regorafenib with PF-03446962 in patients with refractory metastatic colorectal cancer (REGAL-1 trial).
Related ArticlesA phase Ib study of the combination regorafenib with PF-03446962 in patients with refractory metastatic colorectal cancer (REGAL-1 trial). Cancer Chemother Pharmacol. 2019 10;84(4):909-917 Authors: Clarke JM, Blobe GC, Strickler JH, Uronis HE, Zafar SY, Morse M, Dropkin E, Howard L, O'Neill M, Rushing CN, Niedzwiecki D, Watson H, Bolch E, Arrowood C, Liu Y, Nixon AB, Hurwitz HI Abstract PURPOSE: This study aimed to evaluate the maximum...
Angiogenesis inhibitor
1h
Clinical efficacy of daratumumab, pomalidomide, and dexamethasone in patients with relapsed or refractory myeloma: Utility of re-treatment with daratumumab among refractory patients.
Related ArticlesClinical efficacy of daratumumab, pomalidomide, and dexamethasone in patients with relapsed or refractory myeloma: Utility of re-treatment with daratumumab among refractory patients. Cancer. 2019 09 01;125(17):2991-3000 Authors: Nooka AK, Joseph NS, Kaufman JL, Heffner LT, Gupta VA, Gleason C, Boise LH, Lonial S Abstract BACKGROUND: The efficacy of daratumumab (DARA) both as a monotherapy and in combination with standard-of-care regimens...
Angiogenesis inhibitor
1h
The use of phosphodiesterase inhibitors for the treatment of alopecia.
Related ArticlesThe use of phosphodiesterase inhibitors for the treatment of alopecia. J Dermatolog Treat. 2020 May;31(3):245-253 Authors: Juhász MLW, Atanaskova Mesinkovska N Abstract Background: Hair loss encompasses a group of scarring and nonscarring diseases with limited treatment options. Understanding the pathogenesis of alopecias has led to the experimental use of phosphodiesterase inhibitors (PDEi).Objective: To perform a systematic review...
Angiogenesis inhibitor
1h
Maternal preeclampsia and respiratory outcomes in extremely premature infants.
Related ArticlesMaternal preeclampsia and respiratory outcomes in extremely premature infants. Pediatr Res. 2019 04;85(5):693-696 Authors: Tagliaferro T, Jain D, Vanbuskirk S, Bancalari E, Claure N Abstract BACKGROUND: Preeclampsia (PE) is a pregnancy complication characterized by an anti-angiogenic environment. This can affect fetal pulmonary vascular and alveolar development but data of the impact of PE on respiratory outcome in extremely premature...
Angiogenesis inhibitor
1h
Shedding light on IRIS: from Pathophysiology to Treatment of Cryptococcal Meningitis and Immune Reconstitution Inflammatory Syndrome in HIV-Infected Individuals.
Related ArticlesShedding light on IRIS: from Pathophysiology to Treatment of Cryptococcal Meningitis and Immune Reconstitution Inflammatory Syndrome in HIV-Infected Individuals. HIV Med. 2019 01;20(1):1-10 Authors: Balasko A, Keynan Y Abstract OBJECTIVES: The aim of this work was to review current treatment options and propose alternatives for immune reconstitution inflammatory syndrome (IRIS) in HIV-infected individuals with cryptococcal meningitis...
Angiogenesis inhibitor
1h

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου