IJMS, Vol. 21, Pages 3258: Novel Antibodies Targeting MUC1-C Showed Anti-Metastasis and Growth-Inhibitory Effects on Human Breast Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21093258 Authors: Min Jung Kim Jong Rip Choi Nara Tae Tae Min Wi Kristine M. Kim Dae Hee Kim Eung Suk Lee Mucin1 (MUC1) is aberrantly glycosylated and overexpressed in various cancers, and it plays a crucial role in cancerogenesis. MUC1 is a type I membranous protein...
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IJMS, Vol. 21, Pages 3257: Over-Expressing TaSPA-B Reduces Prolamin and Starch Accumulation in Wheat (Triticum aestivum L.) Grains International Journal of Molecular Sciences doi: 10.3390/ijms21093257 Authors: Dandan Guo Qiling Hou Runqi Zhang Hongyao Lou Yinghui Li Yufeng Zhang Mingshan You Chaojie Xie Rongqi Liang Baoyun Li Starch and prolamin composition and content are important indexes for determining the processing and nutritional quality of wheat (Triticum...
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IJMS, Vol. 21, Pages 3256: Inhibition of Xanthine Oxidase-Catalyzed Xanthine and 6-Mercaptopurine Oxidation by Flavonoid Aglycones and Some of Their Conjugates International Journal of Molecular Sciences doi: 10.3390/ijms21093256 Authors: Violetta Mohos Eszter Fliszár-Nyúl Miklós Poór Flavonoids are natural phenolic compounds, which are the active ingredients in several dietary supplements. It is well-known that some flavonoid aglycones are potent inhibitors of the xanthine oxidase...
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IJMS, Vol. 21, Pages 3255: HVCN1 Channels Are Relevant for the Maintenance of Sperm Motility During In Vitro Capacitation of Pig Spermatozoa International Journal of Molecular Sciences doi: 10.3390/ijms21093255 Authors: Yeste Llavanera Mateo-Otero Catalán Bonet Pinart The objective of the present study was to determine the physiological role of voltage-gated hydrogen channels 1 (HVCN1 channels) during in vitro capacitation of pig spermatozoa. Sperm samples from 20...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3253: MicroRNA Nanotherapeutics for Lung Targeting. Insights into Pulmonary Hypertension International Journal of Molecular Sciences doi: 10.3390/ijms21093253 Authors: Susana Carregal-Romero Lucía Fadón Edurne Berra Jesús Ruíz-Cabello In this review, the potential future role of microRNA-based therapies and their specific application in lung diseases is reported with special attention to pulmonary hypertension. Current limitations of these therapies will...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3254: Chronic Systemic Exposure to Low-Dose Rotenone Induced Central and Peripheral Neuropathology and Motor Deficits in Mice: Reproducible Animal Model of Parkinson’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21093254 Authors: Ikuko Miyazaki Nami Isooka Fuminori Imafuku Jin Sun Ryo Kikuoka Chieko Furukawa Masato Asanuma Epidemiological studies demonstrated that pesticide exposure, such as rotenone and paraquat, increases...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3252: Aptamers and Antisense Oligonucleotides for Diagnosis and Treatment of Hematological Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21093252 Authors: Valentina Giudice Francesca Mensitieri Viviana Izzo Amelia Filippelli Carmine Selleri Aptamers or chemical antibodies are single-stranded DNA or RNA oligonucleotides that bind proteins and small molecules with high affinity and specificity by recognizing tertiary or quaternary...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3251: Possible Roles of Periostin in the Formation of Hemodialysis Vascular Access Stenosis after Polytetrafluoroethylene Graft Implantation in Dogs International Journal of Molecular Sciences doi: 10.3390/ijms21093251 Authors: Kenji Watase Denan Jin Kentaro Terai Taketoshi Kanemiya Hyogo Nakakura Nobuhisa Shibahara Shuji Arima Shinji Takai Periostin, a recently found matricellular protein, has been implicated in neointima formation after balloon...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3250: The HD-ZIP II Transcription Factors Regulate Plant Architecture through the Auxin Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21093250 Authors: Guanhua He Pan Liu Huixian Zhao Jiaqiang Sun The homeodomain-leucine zipper (HD-ZIP) family transcription factors play important roles in plant growth and development. However, the underlying mechanisms remain largely unclear. Here we found that ATHB2, encoding a HD-ZIP transcription...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3249: Regulation of Sulfur Homeostasis in Mycorrhizal Maize Plants Grown in a Fe-Limited Environment International Journal of Molecular Sciences doi: 10.3390/ijms21093249 Authors: Styliani N. Chorianopoulou Petros P. Sigalas Niki Tsoutsoura Anastasia Apodiakou Georgios Saridis Yannis E. Ventouris Dimitris L. Bouranis Sulfur is an essential macronutrient for growth of higher plants. The entry of the sulfate anion into the plant, its importation into...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3247: Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials International Journal of Molecular Sciences doi: 10.3390/ijms21093247 Authors: Phiwayinkosi V. Dludla Patrick Orlando Sonia Silvestri Fabio Marcheggiani Ilenia Cirilli Tawanda M. Nyambuya Vuyolwethu Mxinwa Kabelo Mokgalaboni Bongani B. Nkambule Rabia...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3248: Lipids and Lipid-Processing Pathways in Drug Delivery and Therapeutics International Journal of Molecular Sciences doi: 10.3390/ijms21093248 Authors: Milica Markovic Shimon Ben-Shabat Aaron Aponick Ellen M. Zimmermann Arik Dahan The aim of this work is to analyze relevant endogenous lipid processing pathways, in the context of the impact that lipids have on drug absorption, their therapeutic use, and utilization in drug delivery. Lipids may serve...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3245: Human Ovarian Cortex biobanking: A Fascinating Resource for Fertility Preservation in Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21093245 Authors: Erica Silvestris Giuseppe De Palma Stefano Canosa Simone Palini Miriam Dellino Alberto Revelli Angelo Virgilio Paradiso Novel anti-cancer treatments have improved the survival rates of female young patients, reopening pregnancy issues for female cancer survivors affected...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3246: Roles of Histone Acetylation Modifiers and Other Epigenetic Regulators in Vascular Calcification International Journal of Molecular Sciences doi: 10.3390/ijms21093246 Authors: Duk-Hwa Kwon Juhee Ryu Young-Kook Kim Hyun Kook Vascular calcification (VC) is characterized by calcium deposition inside arteries and is closely associated with the morbidity and mortality of atherosclerosis, chronic kidney disease, diabetes, and other cardiovascular diseases...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3244: The Impact of Estrogen Receptor in Arterial and Lymphatic Vascular Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21093244 Authors: Coralie Fontaine Florent Morfoisse Florence Tatin Audrey Zamora Rana Zahreddine Daniel Henrion Jean-François Arnal Françoise Lenfant Barbara Garmy-Susini The lower incidence of cardiovascular diseases in pre-menopausal women compared to men is well-known documented. This protection...
Mon May 04, 2020 03:00
IJMS, Vol. 21, Pages 3243: Biomaterials in Neurodegenerative Disorders: A Promising Therapeutic Approach International Journal of Molecular Sciences doi: 10.3390/ijms21093243 Authors: Matteo Bordoni Eveljn Scarian Federica Rey Stella Gagliardi Stephana Carelli Orietta Pansarasa Cristina Cereda Neurodegenerative disorders (i.e., Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and spinal cord injury) represent a great problem...
Mon May 04, 2020 03:00
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