IJMS, Vol. 21, Pages 3276: Designer Biopolymers: Self-Assembling Proteins and Nucleic Acids International Journal of Molecular Sciences doi: 10.3390/ijms21093276 Authors: Ayae Sugawara-Narutaki Yukiko Kamiya Nature has evolved sequence-controlled polymers such as DNA and proteins over its long history [...]
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IJMS, Vol. 21, Pages 3275: Acute Kidney Injury in SARS-CoV-2 Infection: Direct Effect of Virus on Kidney Proximal Tubule Cells International Journal of Molecular Sciences doi: 10.3390/ijms21093275 Authors: Soleimani Coronaviruses (CoVs), including Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and the novel coronavirus disease-2 (SARS-CoV-2) are a group of enveloped RNA viruses that cause a severe respiratory infection which is associated with a high...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3274: MicroRNA Profiling Reveals an Abundant miR-200a-3p Promotes Skeletal Muscle Satellite Cell Development by Targeting TGF-β2 and Regulating the TGF‑β2/SMAD Signaling Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21093274 Authors: Yin He Shen Tang Zhao Cao Han Cui Chen Wei Wang Li Zhu MicroRNAs (miRNAs) are evolutionarily conserved, small noncoding RNAs that play critical post-transcriptional...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3273: An Ultra-Sensitive Electrochemical Sensor for the Detection of Carcinogen Oxidative Stress 4-Nitroquinoline N-Oxide in Biologic Matrices Based on Hierarchical Spinel Structured NiCo2O4 and NiCo2S4; A Comparative Study International Journal of Molecular Sciences doi: 10.3390/ijms21093273 Authors: Chen Tamilalagan Chen Akilarasan Maheshwaran Liu Various factors leads to cancer; among them oxidative damage is believed to play an important...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3271: Network of Palladium-Based Nanorings Synthesized by Liquid-Phase Reduction Using DMSO-H2O: In Situ Monitoring of Structure Formation and Drying Deformation by ASEM International Journal of Molecular Sciences doi: 10.3390/ijms21093271 Authors: Takuki Komenami Akihiro Yoshimura Yasunari Matsuno Mari Sato Chikara Sato We developed a liquid-phase synthesis method for Pd-based nanostructure, in which Pd dissolved in dimethyl sulfoxide (DMSO) solutions...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3272: Combination Drug Therapy for the Management of Alzheimer’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21093272 Authors: Kabir Uddin Mamun Jeandet Aleya Mansouri Ashraf Mathew Bin-Jumah Abdel-Daim Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Even though the number of AD patients is rapidly growing, there is no effective treatment for this neurodegenerative disorder....
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3265: Elimination of Teratogenic Human Induced Pluripotent Stem Cells by Bee Venom via Calcium-Calpain Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21093265 Authors: Aeyung Kim Seo-Young Lee Bu-Yeo Kim Sun-Ku Chung Induced pluripotent stem cells (iPSCs) are regarded as a promising option for cell-based regenerative medicine. To obtain safe and efficient iPSC-based cell products, it is necessary to selectively eliminate the residual...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3270: Peptide Interference with APP and Tau Association: Relevance to Alzheimer’s Disease Amelioration International Journal of Molecular Sciences doi: 10.3390/ijms21093270 Authors: Ruth Maron Gad Armony Michael Tsoory Meir Wilchek Dan Frenkel Ruth Arnon The two major proteins involved in Alzheimer’s disease (AD) are the amyloid precursor protein (APP) and Tau. Here, we demonstrate that these two proteins can bind to each other. Four possible...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3267: Pharmacological Inhibition of Cyclin-Dependent Kinases Triggers Anti-Fibrotic Effects in Hepatic Stellate Cells In Vitro International Journal of Molecular Sciences doi: 10.3390/ijms21093267 Authors: Anna Hübbers Julia Hennings Daniela Lambertz Ute Haas Christian Trautwein Yulia A. Nevzorova Roland Sonntag Christian Liedtke Liver fibrosis is a wound healing process in response to chronic liver injury, which is characterized by the accumulation...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3262: Whole-Genome Deep Sequencing Reveals Host-Driven in-planta Evolution of Columnea Latent Viroid (CLVd) Quasi-Species Populations International Journal of Molecular Sciences doi: 10.3390/ijms21093262 Authors: Parichate Tangkanchanapas Annelies Haegeman Tom Ruttink Monica Höfte Kris De Jonghe Columnea latent viroid (CLVd) is one of the most serious tomato diseases. In general, viroids have high mutation rates. This generates a population of variants...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3269: Effects of Prenatal Exposure to a Low-Dose of Bisphenol A on Sex Differences in Emotional Behavior and Central Alpha2-Adrenergic Receptor Binding International Journal of Molecular Sciences doi: 10.3390/ijms21093269 Authors: Davide Ponzi Laura Gioiosa Stefano Parmigiani Paola Palanza Prenatal exposure to bisphenol A (BPA) influences the development of sex differences neurologically and behaviorally across many species of vertebrates. These effects...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3266: Aberrant Mitochondrial Morphology and Function in the BTBR Mouse Model of Autism Is Improved by Two Weeks of Ketogenic Diet International Journal of Molecular Sciences doi: 10.3390/ijms21093266 Authors: Younghee Ahn Rasha Sabouny Bianca R. Villa Nellie C. Yee Richelle Mychasiuk Golam M. Uddin Jong M. Rho Timothy E. Shutt Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder that exhibits a common set of behavioral...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3268: CRISPR/Cas9 Editing for Gaucher Disease Modelling International Journal of Molecular Sciences doi: 10.3390/ijms21093268 Authors: Eleonora Pavan Maximiliano Ormazabal Paolo Peruzzo Emilio Vaena Paula Rozenfeld Andrea Dardis Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder caused by mutations in the acid β-glucosidase gene (GBA1). Besides causing GD, GBA1 mutations constitute the main genetic risk factor for developing...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3264: Cholinergic Markers and Cytokines in OSA Patients International Journal of Molecular Sciences doi: 10.3390/ijms21093264 Authors: Marcella Reale Lucia Velluto Marta Di Nicola Chiara D’Angelo Erica Costantini Michele Marchioni Gianluigi Cerroni Biancamaria Guarnieri The role of inflammation and dysfunction of the cholinergic system in obstructive sleep apnea (OSA) has not exhaustively clarified. Thus, in this study, we explore the non-neuronal...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3261: Suppression of the Reactive Oxygen Response Alleviates Experimental Autoimmune Uveitis in Mice International Journal of Molecular Sciences doi: 10.3390/ijms21093261 Authors: Sheng-Min Hsu Chang-Hao Yang Yu-Ti Teng Hsien-Yang Tsai Chieh-Yu Lin Chia-Jhen Lin Chi-Chang Shieh Shun-Hua Chen Reactive oxygen species (ROS) are produced by host phagocytes and play an important role in antimicrobial actions against various pathogens. Autoimmune uveitis...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3263: Revisiting TNF Receptor-Associated Periodic Syndrome (TRAPS): Current Perspectives International Journal of Molecular Sciences doi: 10.3390/ijms21093263 Authors: Cornelia Cudrici Natalie Deuitch Ivona Aksentijevich Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an autosomal dominant autoinflammatory syndrome characterized by prolonged and recurrent episodes of fever, abdominal and/or chest pain, arthralgia, myalgia, and erythematous...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3260: Colorectal Adenomas—Genetics and Searching for New Molecular Screening Biomarkers International Journal of Molecular Sciences doi: 10.3390/ijms21093260 Authors: Anna Siskova Klara Cervena Jan Kral Tomas Hucl Pavel Vodicka Veronika Vymetalkova Colorectal cancer (CRC) is a malignant disease with an incidence of over 1.8 million new cases per year worldwide. CRC outcome is closely related to the respective stage of CRC and is more favorable at less...
Tue May 05, 2020 03:00
IJMS, Vol. 21, Pages 3259: Structure, Function, and Regulation of the Essential Virulence Factor Capsular Polysaccharide of Vibrio vulnificus International Journal of Molecular Sciences doi: 10.3390/ijms21093259 Authors: Gregg S. Pettis Aheli S. Mukerji Vibrio vulnificus populates coastal waters around the world, where it exists freely or becomes concentrated in filter feeding mollusks. It also causes rapid and life-threatening sepsis and wound infections in humans. Of its many virulence...
Tue May 05, 2020 03:00
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