JCM, Vol. 9, Pages 1368: Association between Anxiety and Vascular Dementia Risk: New Evidence and an Updated Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9051368 Authors: Javier Santabárbara Darren M. Lipnicki Beatriz Olaya Beatriz Villagrasa Patricia Gracia-García Juan Bueno-Notivol Antonio Lobo Raúl López-Antón The association between anxiety and vascular dementia (VaD) is unclear. We aimed to reliably estimate the association between anxiety and...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1361: Intrahepatic Cholestasis in Pregnancy: Review of the Literature Journal of Clinical Medicine doi: 10.3390/jcm9051361 Authors: Joanna Piechota Wojciech Jelski Intrahepatic cholestasis of pregnancy (ICP) is the most common hepatic disorder related to pregnancy in women. It usually develops within the third trimester of pregnancy and presents with pruritus as well as elevated levels of bile acid and/or alanine aminotransferase. Clinical signs quickly resolve...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1365: Psychosocial Impact of Predictive Genetic Testing in Hereditary Heart Diseases: The PREDICT Study Journal of Clinical Medicine doi: 10.3390/jcm9051365 Authors: Bordet Brice Maupain Gandjbakhch Isidor Palmyre Moerman Toutain Akloul Brehin Sawka Rooryck-Thambo Schaefer Nguyen Dupin Deguine Rouzier Billy Séné Denjoy Leheup Planes Mazzella Staraci Hebert Le Boette Michon...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1366: Adenosine and the Cardiovascular System: The Good and the Bad Journal of Clinical Medicine doi: 10.3390/jcm9051366 Authors: Guieu Deharo Maille Crotti Torresani Brignole Parati Adenosine is a nucleoside that impacts the cardiovascular system via the activation of its membrane receptors, named A1R, A2AR, A2BR and A3R. Adenosine is released during hypoxia, ischemia, beta-adrenergic stimulation or inflammation and impacts heart rhythm and...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1367: A U-Shaped Relationship Between the Prevalence of Frailty and Body Mass Index in Community-Dwelling Japanese Older Adults: The Kyoto–Kameoka Study Journal of Clinical Medicine doi: 10.3390/jcm9051367 Authors: Watanabe Yoshida Watanabe Yamada Kimura Kyoto-Kameoka Study Group The relationship between body mass index (BMI) and frailty remains unclear. Using two validated frailty assessment tools, this study aimed to investigate the relationship...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1363: Serotonin-Secreting Neuroendocrine Tumours of the Pancreas Journal of Clinical Medicine doi: 10.3390/jcm9051363 Authors: Milanetto Fassan David Pasquali Background: Serotonin-secreting pancreatic neuroendocrine tumours (5-HT-secreting pNETs) are very rare, and characterised by high urinary 5-hydroxyindole-acetic acid (5-HIAA) levels (or high serum 5-HT levels). Methods: Patients with 5-HT-secreting pancreatic neoplasms observed in our unit (1986–2015)...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1359: A Single-Arm, Prospective, Exploratory Study to Preliminarily Test Effectiveness and Safety of Skin Electrical Stimulation for Leber Hereditary Optic Neuropathy Journal of Clinical Medicine doi: 10.3390/jcm9051359 Authors: Kurimoto Ueda Mori Kamada Sakamoto Yamada-Nakanishi Matsumiya Nakamura Leber hereditary optic neuropathy (LHON) is an intractable disease associated with mitochondrial DNA (mtDNA) mutations. In this preliminary,...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1362: Immune Checkpoint Inhibitors for Lung Cancer Treatment: A Review Journal of Clinical Medicine doi: 10.3390/jcm9051362 Authors: Onoi Chihara Uchino Shimamoto Morimoto Iwasaku Kaneko Yamada Takayama The treatment of lung cancer has changed drastically in recent years owing to the advent of immune checkpoint inhibitors (ICIs). A 1992 study reported that programmed cell death-1 (PD-1), an immune checkpoint molecule, is upregulated...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1364: ECG Indices Poorly Predict Left Ventricular Hypertrophy and Are Applicable Only in Individuals With Low Cardiovascular Risk Journal of Clinical Medicine doi: 10.3390/jcm9051364 Authors: Chlabicz Jamiołkowski Paniczko Sowa Szpakowicz Łapińska Jurczuk Kondraciuk Ptaszyńska-Kopczyńska Raczkowski Szpakowicz Kamiński Background: Left ventricular hypertrophy (LVH) is an important risk factor for cardiovascular events. The...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1360: Inflammation-Induced Mucosal KYNU Expression Identifies Human Ileal Crohn’s Disease Journal of Clinical Medicine doi: 10.3390/jcm9051360 Authors: Huhn Juan Melcher Dreis Schmidt Schwiebs Collins Pfeilschifter Vieth Stein Radeke The widely varying therapeutic response of patients with inflammatory bowel disease (IBD) continues to raise questions regarding the unclarified heterogeneity of pathological mechanisms promoting...
Wed May 06, 2020 03:00
JCM, Vol. 9, Pages 1358: Intraosseous Bioplasty for a Subchondral Cyst in the Lateral Condyle of Femur Journal of Clinical Medicine doi: 10.3390/jcm9051358 Authors: Potty Gupta Rodriguez Stone Maffulli Several conditions can lead to the development of a subchondral cyst. The mechanism by which the cysts form, their location, and their severity depend on the underlying pathology, although the exact pathogenesis is not fully elucidated. Treatment options vary according...
Wed May 06, 2020 03:00
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