Pharmaceutics, Vol. 12, Pages 429: Encapsulation of Oleuropein in Nanostructured Lipid Carriers: Biocompatibility and Antioxidant Efficacy in Lung Epithelial Cells

Pharmaceutics, Vol. 12, Pages 429: Encapsulation of Oleuropein in Nanostructured Lipid Carriers: Biocompatibility and Antioxidant Efficacy in Lung Epithelial Cells Pharmaceutics doi: 10.3390/pharmaceutics12050429 Authors: Huguet-Casquero Moreno-Sastre López-Méndez Gainza Pedraz Oxidative damage has been linked to a number of diseases. Oleuropein (OLE), a natural occurring polyphenol from olive leaves (Olea europaea L.), is known to be a potent antioxidant compound with...

Pharmaceutics

Wed May 06, 2020 03:00

Pharmaceutics, Vol. 12, Pages 427: Physical Properties of an Ionic Liquid Composed of Two Water-Soluble Vitamins and Enhanced Skin Permeation of Both Vitamins

Pharmaceutics, Vol. 12, Pages 427: Physical Properties of an Ionic Liquid Composed of Two Water-Soluble Vitamins and Enhanced Skin Permeation of Both Vitamins Pharmaceutics doi: 10.3390/pharmaceutics12050427 Authors: Sugibayashi Yoshida Suzuki Yoshizawa Mori Itakura Takayama Todo : A highly viscous substance was prepared by evaporating an ethanol solution containing two hydrophilic vitamins; vitamin C, and vitamin B6. The viscous substance and physical mixture...

Pharmaceutics

Wed May 06, 2020 03:00

Pharmaceutics, Vol. 12, Pages 425: Qualification of Non-Halogenated Organic Solvents Applied to Microsphere Manufacturing Process

Pharmaceutics, Vol. 12, Pages 425: Qualification of Non-Halogenated Organic Solvents Applied to Microsphere Manufacturing Process Pharmaceutics doi: 10.3390/pharmaceutics12050425 Authors: Shim Sah As a non-halogenated dispersed solvent, ethyl acetate has been most commonly used for the manufacturing of poly-d,l-lactide-co-glycolide (PLGA) microspheres. However, ethyl acetate-based microencapsulation processes face several limitations. This study was aimed at proposing ethyl formate...

Pharmaceutics

Wed May 06, 2020 03:00

Pharmaceutics, Vol. 12, Pages 428: Adjuvant Drug-Assisted Bone Healing: Advances and Challenges in Drug Delivery Approaches

Pharmaceutics, Vol. 12, Pages 428: Adjuvant Drug-Assisted Bone Healing: Advances and Challenges in Drug Delivery Approaches Pharmaceutics doi: 10.3390/pharmaceutics12050428 Authors: Rothe Hauser Neuber Laube Schulze Rammelt Pietzsch Bone defects of critical size after compound fractures, infections, or tumor resections are a challenge in treatment. Particularly, this applies to bone defects in patients with impaired bone healing due to frequently occurring metabolic...

Pharmaceutics

Wed May 06, 2020 03:00

Pharmaceutics, Vol. 12, Pages 426: In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier

Pharmaceutics, Vol. 12, Pages 426: In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier Pharmaceutics doi: 10.3390/pharmaceutics12050426 Authors: Alvebratt Dening Åhlén Cheung Strømme Gogoll Prestidge Bergström Lipid-based formulations can circumvent the low aqueous solubility of problematic drug compounds and increase their oral absorption. As these formulations are often physically...

Pharmaceutics

Wed May 06, 2020 03:00

Pharmaceutics, Vol. 12, Pages 424: In Vitro Intracellular Hyperthermia of Iron Oxide Magnetic Nanoparticles, Synthesized at High Temperature by a Polyol Process

Pharmaceutics, Vol. 12, Pages 424: In Vitro Intracellular Hyperthermia of Iron Oxide Magnetic Nanoparticles, Synthesized at High Temperature by a Polyol Process Pharmaceutics doi: 10.3390/pharmaceutics12050424 Authors: Cristian Iacovita Ionel Fizeșan Anca Pop Lavinia Scorus Roxana Dudric Gabriela Stiufiuc Nicoleta Vedeanu Romulus Tetean Felicia Loghin Rares Stiufiuc Constantin Mihai Lucaciu We report the synthesis of magnetite nanoparticles (IOMNPs) using...

Pharmaceutics

Wed May 06, 2020 03:00