Τρίτη 5 Μαΐου 2020

Organ-specific propensity drives patterns of gene expression evolution [NEW RESULTS]
The origins of multicellular physiology are tied to evolution of gene expression. Genes can shift expression as organisms evolve, but how ancestral expression influences altered descendant expression is not well understood. To examine this, we amalgamated 1,903 RNA-seq datasets from 182 research projects, including 6 organs in 21 vertebrate species. Quality control eliminated project-specific biases, and expression shifts were reconstructed using gene-family-wise phylogenetic Ornstein-Uhlenbeck models....
bioRxiv Subject Collection: Evolutionary Biology
Tue May 05, 2020 03:00

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