Antibiotics, Vol. 8, Pages 195: Veterinary Drug Shops as Main Sources of Supply and Advice on Antimicrobials for Animal Use in the Mekong Delta of Vietnam Antibiotics doi: 10.3390/antibiotics8040195 Authors: Doan Hoang Phu Vu Thi Quynh Giao Dinh Bao Truong Nguyen Van Cuong Bach Tuan Kiet Vo Be Hien Guy Thwaites Jonathan Rushton Juan Carrique-Mas In the Mekong Delta of Vietnam, small-scale poultry farmers use large amounts of antimicrobials to raise their flocks,...
Fri Oct 25, 2019 03:00
Antioxidants, Vol. 8, Pages 512: Gastro-Protective and Anti-Oxidant Potential of Althaea officinalis and Solanum nigrum on Pyloric Ligation/Indomethacin-Induced Ulceration in Rats Antioxidants doi: 10.3390/antiox8110512 Authors: Sameh S. Zaghlool Ali A. Abo-Seif Mohamed A. Rabeh Usama Ramadan Abdelmohsen Basim A. S. Messiha Recently, an alternative disease treatment approach is the research of medicaments from traditional medicine. Plants with anti-oxidant capabilities are...
Fri Oct 25, 2019 03:00
Antioxidants, Vol. 8, Pages 510: Anthocyanin Accumulation in Black Kernel Mutant Rice and its Contribution to ROS Detoxification in Response to High Temperature at the Filling Stage Antioxidants doi: 10.3390/antiox8110510 Authors: Syed Hassan Raza Zaidi Shamsu Ado Zakari Qian Zhao Ali Raza Khan Jawad Munawar Shah Fangmin Cheng Effect of high temperature (HT) on anthocyanin (ANS) accumulation and its relationship with reactive oxygen species (ROS) generation in color rice...
Fri Oct 25, 2019 03:00
Antioxidants, Vol. 8, Pages 511: Vitamin D and Gestational Diabetes Mellitus: Is There a Link? Antioxidants doi: 10.3390/antiox8110511 Authors: Gianluca Rizzo Simone Garzon Michele Fichera Marco Marzio Panella Ursula Catena Antonio Schiattarella Pasquale de Franciscis George Vilos Jan Tesarik Péter Török Giuseppe Grosso Gestational diabetes mellitus (GDM) is a very common condition among pregnant women worldwide with important metabolic implications on the...
Fri Oct 25, 2019 03:00
Arts, Vol. 8, Pages 143: A Search for the Hidden King: Messianism, Prophecies and Royal Epiphanies of the Kings of Aragon (circa 1250–1520) Arts doi: 10.3390/arts8040143 Authors: Serra Desfilis Modern historiography has studied the influence of messianic and millennialist ideas in the Crown of Aragon extensively and, more particularly, how they were linked to the Aragonese monarchy. To date, research in the field of art history has mainly considered royal iconography from a different...
Fri Oct 25, 2019 03:00
Atmosphere, Vol. 10, Pages 649: Characteristics and Formation Mechanisms of Spring SST Anomalies in the South China Sea and Its Adjacent Regions Atmosphere doi: 10.3390/atmos10110649 Authors: Wenjuan Gao Song Yang Xiaoming Hu Wei Wei Yanglin Xiao Characteristics of the springtime sea surface temperature anomalies (SSTAs) in the South China Sea and its adjacent regions (SCSAR), as well as their possible impacts on the Asian and Indo-Pacific climate, were investigated by using...
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Atmosphere, Vol. 10, Pages 648: Evaluating the Forecast Performance of the Meiyu Front Rainbelt Position: A Case Study of the 30 June to 4 July 2016 Extreme Rainfall Event Atmosphere doi: 10.3390/atmos10110648 Authors: Jie Ma Kevin A. Bowley Fuqing Zhang An impactful and poorly forecasted heavy rainfall event was observed in association with the Meiyu front over the Yangtze River valley of China from 30 June–4 July 2016. Operational global numerical weather prediction...
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Atmosphere, Vol. 10, Pages 647: A Cohort Study on Respiratory Symptoms and Diseases Caused by Toner-Handling Work: Longitudinal Analyses from 2003 to 2013 Atmosphere doi: 10.3390/atmos10110647 Authors: Niina Terunuma Kazunori Ikegami Hiroko Kitamura Hajime Ando Shizuka Kurosaki Masashi Masuda Takeshi Kochi Nobuaki Yanagi Akira Ogami Toshiaki Higashi The purpose of this study was to examine the effects of toner-handling work on respiratory symptoms and diseases....
Fri Oct 25, 2019 03:00
Atmosphere, Vol. 10, Pages 646: Climate Preferences for Tourism: Perceptions Regarding Ideal and Unfavourable Conditions for Hiking in Spain Atmosphere doi: 10.3390/atmos10110646 Authors: Emilio Martínez-Ibarra María Belén Gómez-Martín Xosé Anton Armesto-López Rubén Pardo-Martínez Physical activity is an increasingly frequent part of our leisure time. Within this context, hiking is a popular form of tourism which has a positive impact on the quality of life. In spite of the...
Fri Oct 25, 2019 03:00
Atmosphere, Vol. 10, Pages 645: Characteristics of PM2.5 at a High-Altitude Remote Site in the Southeastern Margin of the Tibetan Plateau in Premonsoon Season Atmosphere doi: 10.3390/atmos10110645 Authors: Zhuzi Zhao Qiyuan Wang Li Li Yongming Han Zhaolian Ye Siwatt Pongpiachan Yong Zhang Suixin Liu Ruixia Tian Junji Cao The Tibetan Plateau (TP) is one of the world’s most sensitive areas for climate change. Previous studies have revealed that air...
Fri Oct 25, 2019 03:00
Biology, Vol. 8, Pages 81: Hormonal Regulation of Glucocorticoid Inactivation and Reactivation in αT3-1 and LβT2 Gonadotroph Cells Biology doi: 10.3390/biology8040081 Authors: Anthony E. Michael Lisa M. Thurston Robert C. Fowkes The regulation of reproductive function by glucocorticoids occurs at all levels of the hypothalamo-pituitary-gonadal axis. Within the pituitary, glucocorticoids have been shown to directly alter gene expression in gonadotrophs, indicating that these cell...
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Biomolecules, Vol. 9, Pages 658: Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection Biomolecules doi: 10.3390/biom9110658 Authors: Chen Peng Wang Hu Shen Xu Yin Liu Cao Schistosomiasis caused by Schistosoma japonicum is a major parasitic disease in the People’s Republic of China. Liver fibrosis is the main pathological mechanism of schistosomiasis, and it is also the major...
Fri Oct 25, 2019 03:00
Biomolecules, Vol. 9, Pages 656: A Computational Framework for Predicting Direct Contacts and Substructures within Protein Complexes Biomolecules doi: 10.3390/biom9110656 Authors: Mei Zhang Understanding the physical arrangement of subunits within protein complexes potentially provides valuable clues about how the subunits work together and how the complexes function. The majority of recent research focuses on identifying protein complexes as a whole and seldom studies the inner...
Fri Oct 25, 2019 03:00
Biomolecules, Vol. 9, Pages 657: Strategies for Developing Functional Secretory Epithelia from Porcine Salivary Gland Explant Outgrowth Culture Models Biomolecules doi: 10.3390/biom9110657 Authors: Urkasemsin Castillo Rungarunlert Klincumhom Ferreira Research efforts have been made to develop human salivary gland (SG) secretory epithelia for transplantation in patients with SG hypofunction and dry mouth (xerostomia). However, the limited availability of human biopsies...
Fri Oct 25, 2019 03:00
Biomolecules, Vol. 9, Pages 654: Use of Cardiac Biomarkers for Monitoring Improvement of Left Ventricular Function by Immunoadsorption Treatment in Dilated Cardiomyopathy Biomolecules doi: 10.3390/biom9110654 Authors: Weinmann Werner Koenig Rottbauer Walcher Keßler Immunoadsorption and subsequent administration of intravenous immunoglobulin (IVIG) have shown beneficial effects on cardiac function and symptoms in patients with dilated cardiomyopathy. Biomarkers play...
Fri Oct 25, 2019 03:00
Biomolecules, Vol. 9, Pages 655: Interactions of 7,8-Dihydroxyflavone with Serum Albumin as well as with CYP2C9, CYP2C19, CYP3A4, and Xanthine Oxidase Biotransformation Enzymes Biomolecules doi: 10.3390/biom9110655 Authors: Fliszár-Nyúl Mohos Bencsik Lemli Kunsági-Máté Poór 7,8-dihydroxyflavone (DHF) is a flavone aglycone which has beneficial effects in several central nervous system diseases. Most of the pharmacokinetic properties of DHF have been characterized,...
Fri Oct 25, 2019 03:00
Biomolecules, Vol. 9, Pages 650: Disease Associated Mutations in KIR Proteins Linked to Aberrant Inward Rectifier Channel Trafficking Biomolecules doi: 10.3390/biom9110650 Authors: Eva-Maria Zangerl-Plessl Muge Qile Meye Bloothooft Anna Stary-Weinzinger Marcel A. G. van der Heyden The ubiquitously expressed family of inward rectifier potassium (KIR) channels, encoded by KCNJ genes, is primarily involved in cell excitability and potassium homeostasis. Channel mutations associate...
Fri Oct 25, 2019 03:00
Biomolecules, Vol. 9, Pages 652: Dynamics of Solid Proteins by Means of Nuclear Magnetic Resonance Relaxometry Biomolecules doi: 10.3390/biom9110652 Authors: Danuta Kruk Elzbieta Masiewicz Anna M. Borkowska Pawel Rochowski Pascal H. Fries Lionel M. Broche David J. Lurie 1H Nuclear magnetic resonance (NMR) relaxometry was exploited to investigate the dynamics of solid proteins. The relaxation experiments were performed at 37 °C over a broad frequency range, from...
Fri Oct 25, 2019 03:00
Biomolecules, Vol. 9, Pages 653: Transcriptome Profile Alteration with Cadmium Selenide/Zinc Sulfide Quantum Dots in Saccharomyces cerevisiae Biomolecules doi: 10.3390/biom9110653 Authors: Cullen Horstmann Daniel S Kim Chelsea Campbell Kyoungtae Kim Quantum Dots (QDs) are becoming more prevalent in products used in our daily lives, such as TVs and laptops, due to their unique and tunable optical properties. The possibility of using QDs as fluorescent probes in applications,...
Fri Oct 25, 2019 03:00
Biomolecules, Vol. 9, Pages 651: Immunotherapy of Hepatocellular Carcinoma with Magnetic PD-1 Peptide-Imprinted Polymer Nanocomposite and Natural Killer Cells Biomolecules doi: 10.3390/biom9110651 Authors: Mei-Hwa Lee Kai-Hsi Liu James L. Thomas Jyun-Ren Chen Hung-Yin Lin Programmed cell death protein 1 (PD-1) is a biomarker on the surface of cells with a role in promoting self-tolerance by suppressing the inflammatory activity of T cells. In this work, one peptide of PD-1...
Fri Oct 25, 2019 03:00
Brain Sciences, Vol. 9, Pages 293: Investigation of Biochemical Alterations in Ischemic Stroke Using Fourier Transform Infrared Imaging Spectroscopy—A Preliminary Study Brain Sciences doi: 10.3390/brainsci9110293 Authors: Rakib Ali Yousuf Afifi Bhatt Ullah Al-Saad Ali Objective: Brain damage, long-term disability and death are the dreadful consequences of ischemic stroke. It causes imbalance in the biochemical constituents that distorts the brain dynamics....
Fri Oct 25, 2019 03:00
Brain Sciences, Vol. 9, Pages 292: Amantadine Improves Delayed Neuropsychiatric Sequelae of Carbon Monoxide Poisoning: A Case Report Brain Sciences doi: 10.3390/brainsci9110292 Authors: Tomosuke Nakano Toshiki Hasegawa Dai Suzuki Eishi Motomura Motohiro Okada Carbon monoxide (CO) poisoning causes severe brain damage, including delayed neuropsychiatric sequelae (DNS), which occur after a lucid interval following recovery from the insult of acute CO poisoning. We describe a...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1656: High Clinical Value of Liquid Biopsy to Detect Circulating Tumor Cells and Tumor Exosomes in Pancreatic Ductal Adenocarcinoma Patients Eligible for Up-Front Surgery Cancers doi: 10.3390/cancers11111656 Authors: Etienne Buscail Catherine Alix-Panabières Pascaline Quincy Thomas Cauvin Alexandre Chauvet Olivier Degrandi Charline Caumont Séverine Verdon Isabelle Lamrissi Isabelle Moranvillier Camille Buscail Marion Marty Christophe...
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Cancers, Vol. 11, Pages 1655: Cachectic Body Composition and Inflammatory Markers Portend a Poor Prognosis in Patients with Locally Advanced Pancreatic Cancer Treated with Chemoradiation Cancers doi: 10.3390/cancers11111655 Authors: Patrick Naumann Jonathan Eberlein Benjamin Farnia Jakob Liermann Thilo Hackert Jürgen Debus Stephanie E. Combs Background: Patients with pancreatic cancer often develop cancer cachexia, a complex multifactorial syndrome with weight loss,...
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Cancers, Vol. 11, Pages 1653: Oxygen Tension Regulates Lysosomal Activation and Receptor Tyrosine Kinase Degradation Cancers doi: 10.3390/cancers11111653 Authors: Hong Wuest Min Lin Oxygen sensing is crucial for adaptation to variable habitats and physiological conditions. Low oxygen tension, or hypoxia, is a common feature of solid tumors, and hypoxic tumors are often more aggressive and resistant to therapy. Here we show that, in cultured mammalian cells, hypoxia suppressed...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1652: Role of Non-Coding RNAs in the Progression of Liver Cancer: Evidence from Experimental Models Cancers doi: 10.3390/cancers11111652 Authors: April O’Brien Tianhao Zhou Christopher Tan Gianfranco Alpini Shannon Glaser Liver cancer is a devastating cancer that ranges from relatively rare (around 2% of all cancers in the United States) to commonplace (up to 50% of cancers in underdeveloped countries). Depending upon the stage of pathogenesis, prognosis,...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1654: Synergism Through WEE1 and CHK1 Inhibition in Acute Lymphoblastic Leukemia Cancers doi: 10.3390/cancers11111654 Authors: Ghelli Luserna Di Rorà Bocconcelli Ferrari Terragna Bruno Imbrogno Beeharry Robustelli Ghetti Napolitano Chirumbolo Marconi Papayannidis Paolini Sartor Simonetti Yen Martinelli Introduction: Screening for synthetic lethality markers has demonstrated that the inhibition...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1650: The Role of Aberrant DNA Methylation in Misregulation of Gene Expression in Gonadotroph Nonfunctioning Pituitary Tumors Cancers doi: 10.3390/cancers11111650 Authors: Paulina Kober Joanna Boresowicz Natalia Rusetska Maria Maksymowicz Agnieszka Paziewska Michalina Dąbrowska Jacek Kunicki Wiesław Bonicki Jerzy Ostrowski Janusz A. Siedlecki Mateusz Bujko Gonadotroph nonfunctioning pituitary adenomas (NFPAs) are common intracranial...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1648: Genomic Perspective on Mouse Liver Cancer Models Cancers doi: 10.3390/cancers11111648 Authors: Sun Young Yim Ju-Seog Lee Selecting the most appropriate mouse model that best recapitulates human hepatocellular carcinoma (HCC) allows translation of preclinical mouse studies into clinical studies. In the era of cancer genomics, comprehensive and integrative analysis of the human HCC genome has allowed categorization of HCC according to molecular subtypes....
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1649: NPY Gene Methylation as a Universal, Longitudinal Plasma Marker for Evaluating the Clinical Benefit from Last-Line Treatment with Regorafenib in Metastatic Colorectal Cancer Cancers doi: 10.3390/cancers11111649 Authors: Lars Henrik Jensen René Olesen Lone Noergaard Petersen Anders Kindberg Boysen Rikke Fredslund Andersen Jan Lindebjerg Lise Nottelmann Caroline Emilie Brenner Thomsen Birgitte Mayland Havelund Anders Jakobsen Torben...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1651: Identification of SERPINE1 as a Regulator of Glioblastoma Cell Dispersal with Transcriptome Profiling Cancers doi: 10.3390/cancers11111651 Authors: Fidan Seker Ahmet Cingoz İlknur Sur-Erdem Nazli Erguder Alp Erkent Fırat Uyulur Myvizhi Esai Selvan Zeynep Hülya Gümüş Mehmet Gönen Halil Bayraktar Hiroaki Wakimoto Tugba Bagci-Onder High mortality rates of glioblastoma (GBM) patients are partly attributed to the invasive behavior...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1644: The Differential Impact of SRC Expression on the Prognosis of Patients with Head and Neck Squamous Cell Carcinoma Cancers doi: 10.3390/cancers11111644 Authors: Francisco Hermida-Prado Rocío Granda-Díaz Nagore del-Río-Ibisate M. Ángeles Villaronga Eva Allonca Irati Garmendia Luis M. Montuenga René Rodríguez Aitana Vallina César Alvarez-Marcos Juan P. Rodrigo Juana M. García-Pedrero Aberrant SRC expression and activation is...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1647: Tumor and Cerebrospinal Fluid microRNAs in Primary Central Nervous System Lymphomas Cancers doi: 10.3390/cancers11111647 Authors: Michalina Zajdel Grzegorz Rymkiewicz Maria Sromek Maria Cieslikowska Pawel Swoboda Mariusz Kulinczak Krzysztof Goryca Zbigniew Bystydzienski Katarzyna Blachnio Beata Ostrowska Anita Borysiuk Agnieszka Druzd-Sitek Jan Walewski Magdalena Chechlinska Jan Konrad Siwicki Primary central nervous...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1645: Computerized Cytological Features for Papillary Thyroid Cancer Diagnosis—Preliminary Report Cancers doi: 10.3390/cancers11111645 Authors: Shyang-Rong Shih I-Shiow Jan Kuen-Yuan Chen Wan-Yu Chuang Chih-Yuan Wang Yung-Lien Hsiao Tien-Chun Chang Argon Chen Fine needle aspiration cytology (FNAC) is the final diagnosis of thyroid nodules before surgery. It is important to further improve the indeterminate FNAC diagnosis results using computerized...
Fri Oct 25, 2019 03:00
Cancers, Vol. 11, Pages 1646: STAT3: An Emerging Therapeutic Target for Hepatocellular Carcinoma Cancers doi: 10.3390/cancers11111646 Authors: Carol Lee Siu Tim Cheung Hepatocellular carcinoma (HCC) is a major global health problem and its treatment options have been limited. Signal transducer and activator of transcription 3 (STAT3) is a transcription factor important for various cellular processes. Overexpression and constitutive activation of STAT3 have been frequently found in...
Fri Oct 25, 2019 03:00
Cells, Vol. 8, Pages 1323: Comprehensive Profiling of Surface Gangliosides Extracted from Various Cell Lines by LC-MS/MS Cells doi: 10.3390/cells8111323 Authors: Jua Lee Heeyoun Hwang Sumin Kim Jaeyun Hwang Jaekyung Yoon Dongtan Yin Sun Il Choi Yun-Hee Kim Yong-Sam Kim Hyun Joo An Gangliosides act as a surface marker at the outer cellular membrane and play key roles in cancer cell invasion and metastasis. Despite the biological importance of gangliosides, they...
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Cells, Vol. 8, Pages 1322: Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia Cells doi: 10.3390/cells8111322 Authors: Barve Vega Shah Ghare Casson Wunderlich Siskind Beverly Leukemias bearing mixed lineage leukemia (MLL) rearrangement (MLL-R) resulting in expression of oncogenic MLL fusion proteins (MLL-FPs) represent an especially aggressive disease subtype with the worst overall prognoses and...
Fri Oct 25, 2019 03:00
Cells, Vol. 8, Pages 1320: Wnt Glycation Inhibits Canonical Signaling Cells doi: 10.3390/cells8111320 Authors: Ye Mittag Schmidt Simm Horstkorte Huber Glycation occurs as a non-enzymatic reaction between amino and thiol groups of proteins, lipids, and nucleotides with reducing sugars or -dicarbonyl metabolites. The chemical reaction underlying is the Maillard reaction leading to the formation of a heterogeneous group of compounds named advanced glycation end products...
Fri Oct 25, 2019 03:00
Cells, Vol. 8, Pages 1321: Transcriptional Regulation of Autophagy Genes via Stage-Specific Activation of CEBPB and PPARG during Adipogenesis: A Systematic Study Using Public Gene Expression and Transcription Factor Binding Datasets Cells doi: 10.3390/cells8111321 Authors: Mahmoud Ahmed Trang Huyen Lai Jin Seok Hwang Sahib Zada Trang Minh Pham Deok Ryong Kim Autophagy is the cell self-eating mechanism to maintain cell homeostasis by removing damaged intracellular proteins...
Fri Oct 25, 2019 03:00
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