Abstract Atherosclerosis is a major cause of mortalities and morbidities worldwide. It is associated with hyperlipidemia and inflammation, and become chronic by triggering metabolites in different metabolic pathways. Disturbance in the human gut microbiota is now considered a critical factor in the atherosclerosis. Trimethylamine-N-oxide (TMAO) attracts attention and is regarded as a vital contributor in the development of atherosclerosis. TMAO is generated from its dietary precursors...
Sat Oct 26, 2019 03:00
Publication date: Available online 25 October 2019Source: American Journal of OtolaryngologyAuthor(s): K.K. Bommakanti, W.J. Moss, R.A. Weisman, P.A. WeissbrodAbstractObjectivesThe objective of this study is to analyze and report the institution's experience using the Enseal bipolar tissue sealing device to perform endoscopic Zenker's diverticulotomy. Safety and early functional outcomes are presented as primary endpoints of the study.Materials & methodsThis is a retrospective study of consecutive...
Sat Oct 26, 2019 18:38
Publication date: Available online 25 October 2019Source: Radiotherapy and OncologyAuthor(s): Wei Wei, Ke Wang, Zhenyu Liu, Kaibing Tian, Liang Wang, Jiang Du, Junpeng Ma, Shuo Wang, Longfei Li, Rui Zhao, Luo Cui, Zhen Wu, Jie TianAbstractBackground and purposeWe used radiomic analysis to establish a radiomic signature based on anatomical magnetic resonance imaging (MRI) sequences and explore its effectiveness as a novel prognostic biomarker for skull base chordoma (SBC).Materials and methodsIn this...
Sat Oct 26, 2019 18:19
Publication date: Available online 25 October 2019Source: Journal of VoiceAuthor(s): Matthias Echternach, Catalina Högerle, Marie Köberlein, Patrick Schlegel, Michael Döllinger, Bernhard Richter, Marie-Anne KainzSummaryIntroductionIt is generally assumed that when singing across the region where registration events for untrained voices occur (the passaggio), singers modify the voice production system in order to avoid changes of voice quality. In this context, it has been postulated that nasalance...
Sat Oct 26, 2019 18:11
Publication date: Available online 25 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Rongzhou He, Yanchen Ye, Zilun Li, Yu Jiang, Yonghui Li, Yunyan Liu, Kangjie Wang, Chen Yao
Sat Oct 26, 2019 18:10
Publication date: Available online 25 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Axel Haine, Martin J. Schmid, Marc Schindewolf, Armando Lenz, Sarah M. Bernhard, Heinz Drexel, Iris Baumgartner, Jörn F. DopheideObjectivesInformation on performance of different stent platforms in endovascular revascularisation of femoropopliteal lesions is controversial and scarce.MethodsInterwoven nitinol (INS, Supera) were compared with drug eluting (DES, Zilver PTx) stents...
Sat Oct 26, 2019 18:10
Publication date: Available online 25 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Christos Liapis, Efthymios D. Avgerinos, Hans-Henning Eckstein
Sat Oct 26, 2019 18:10
Publication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Nagla A. El-Shitany, Basma G. EidAbstractCellular inflammation has been recognized as the leading factor in numerous diseases, causing either cell death, organ-specific damage, or genesis of different cancers. Icariin, a flavonol glucoside, extracted from Herba Epimedii, offers various pharmacological activities, including reducing inflammation and an antioxidant effect. We aimed to evaluate the anti-inflammatory...
Sat Oct 26, 2019 18:04
Publication date: January 2020Source: Magnetic Resonance Imaging, Volume 65Author(s): Saeed Jerban, Eric Y. Chang, Jiang DuAbstractOsteoarthritis (OA) is a very common disease that affects the human knee joint, particularly the articular cartilage and meniscus components which are regularly under compressive mechanical loads. Early-stage OA diagnosis is essential as it allows for timely intervention. The primary non-invasive approaches currently available for OA diagnosis include magnetic resonance...
Sat Oct 26, 2019 18:02
Publication date: January 2020Source: Magnetic Resonance Imaging, Volume 65Author(s): Ponnada A. Narayana, Ivan Coronado, Sheeba J. Sujit, Xiaojun Sun, Jerry S. Wolinsky, Refaat E. GabrAbstractBackgroundMagnetic resonance images with multiple contrasts or sequences are commonly used for segmenting brain tissues, including lesions, in multiple sclerosis (MS). However, acquisition of images with multiple contrasts increases the scan time and complexity of the analysis, possibly introducing factors...
Sat Oct 26, 2019 18:02
Publication date: Available online 25 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Natale Ferreira Gontijo-de-Amorim, Luiz Charles-de-Sá, Gino Rigotti
Sat Oct 26, 2019 17:53
Publication date: Available online 25 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Lee L.Q. Pu
Sat Oct 26, 2019 17:53
Publication date: Available online 25 October 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Elena Crestani, Hani Harb, Louis-Marie Charbonnier, Jonathan Leirer, Alison Motsinger-Reif, Rima Rachid, Wanda Phipatanakul, Rima Kaddurah-Daouk, Talal A. ChatilaAbstractBackgroundFood allergy (FA) affects an increasing proportion of children. for reasons that remain obscure. Novel disease biomarkers and curative treatment options are strongly needed.ObjectiveTo apply untargeted metabolomic...
Sat Oct 26, 2019 17:49
Publication date: Available online 25 October 2019Source: Journal of Neuroscience MethodsAuthor(s): Barilin Dkhar, Abhijeet Bhatia, Pranjal Pratim Saikia, Haphidasara PyngropeABSTRACTObjectivesResearch using rat as an in-vivo model has played an important role in otological research. The rat ear anatomy has been described; however, detailed surgical procedures to access the temporal bone are limited. The authors present a technique to approach the inner ear of rat that was standardized by cadaveric...
Sat Oct 26, 2019 17:35
Abstract To understand the influence of social relationships on cardiovascular responses to stress, the present study investigated perceived affectionate support as a mediating variable explaining the association between specific attachment bonds (i.e., mother, father, partner, best friend) and cardiovascular reactivity (CVR). Utilizing a standardized stress testing protocol, 138 young adults completed measures of attachment and social support, with continuous cardiovascular measurements obtained...
Fri Oct 25, 2019 19:53
Publication date: Available online 25 October 2019Source: Journal of Bodywork and Movement TherapiesAuthor(s): Christopher M. NorrisAbstractExercise is vital to the management of low back pain (LBP). However, research, social media, and fitness industry interests can leave therapists confused about best practice in exercise prescription for this clinical condition. The 3R’s approach to back rehabilitation is introduced as an evidence-based framework for developing patient specific exercise throughout...
Sat Oct 26, 2019 17:19
Publication date: Available online 25 October 2019Source: Journal of Bodywork and Movement TherapiesAuthor(s): Galit PazAbstractBackgroundCharcot-Marie-Tooth (CMT) disease, a progressive hereditary peripheral neuropathy, leads to muscle weakness, wasting, and sensory and motor nerve deprivation. The two main types of CMT are CMT1 (demyelinating) and CMT2 (axonal). Initial findings include foot deformities and sensory changes with progression to altered gait, diminished reflexes, and muscle wasting...
Sat Oct 26, 2019 17:19
Publication date: Available online 25 October 2019Source: International Journal of PsychophysiologyAuthor(s): Fanny Grisetto, Yvonne N. Delevoye-Turrell, Clémence RogerAbstractAggressive behaviors in pathological and healthy populations have been largely related to poor cognitive control functioning. However, few studies have investigated the influence of aggressive traits (i.e., aggressiveness) on cognitive control. In the current study, we investigated the effects of aggressiveness on cognitive...
Sat Oct 26, 2019 17:19
Publication date: Available online 25 October 2019Source: International Journal of PsychophysiologyAuthor(s): Nick Beligiannis, Jan W. Van StrienAbstractPrevious event-related potential studies have reported enhanced Early Posterior Negativity (EPN) in response to snake pictures compared to pictures of other animals. This EPN snake effect may be partly driven by specific snake skin patterns. In this study, by using blurred pictures to make these patterns less visible, we explored whether the relative...
Sat Oct 26, 2019 17:19
Publication date: Available online 25 October 2019Source: International Journal of PsychophysiologyAuthor(s): Timm Rosburg, Michael Weigl, Gunnar DeuringAbstractIt is as yet unresolved to what extent the pre-attentive detection of auditory deviance is modulated by emotion. The current event-related potential study was designed to investigate simultaneously the auditory and the visual mismatch negativity (MMN), as well as the impact of emotion on the auditory MMN. Thirty healthy participants saw sequences...
Sat Oct 26, 2019 17:19
Abstract The binding of alkaline earth cations Mg2+, Ca2+, and Sr2+ (M2+) to unilamellar 1,2-dimyristoyl-sn-glycero-3-phosphatidic acid (DMPA) vesicles was analysed by pH potentiometry, differential scanning calorimetry (DSC), isothermal titration calorimetry (ITC) and FT-IR spectroscopy. The binding of alkaline earth cations induces deprotonation of the DMPA headgroup even at very low concentration of divalent cations (~ 100 µM). The amount of deprotonated DMPA was measured by...
Sat Oct 26, 2019 03:00
Abstract Aggregation of amyloid- \(\beta \) (Aβ) peptides, cleaved from the amyloid precursor protein, is known as a precursor of the Alzheimer’s disease (AD). It is also known that Alzheimer’s disease is characterized by a substantial decrease of the amount of polyunsaturated lipids in the neuronal membranes of the frontal gray matter. To get insight into possible interconnection of these...
Sat Oct 26, 2019 03:00
Abstract We studied the complex between ovalbumin and long flexible poly-(sodium 4-styrene sulfonate) as a function of pH and temperature. We used various techniques [turbidimetry, conductometry, dynamic light scattering, viscosimetry, and ultra-small-angle light scattering (USALS)] to fully characterize the coacervate complex. Different phases of complexation versus temperature were determined by turbidimetric analysis (pHc, pHϕ1, and pHϕ2). The optimal protein/polyelectrolyte...
Sat Oct 26, 2019 03:00
Publication date: Available online 25 October 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Tamir Dean Anver, Lida Mirzai, Peng Li, Kathlyn Powell, Peter D. WaiteAbstractPurposeUse cone-beam computed tomography (CBCT) analysis to assess the long term radiographic outcomes of early secondary alveolar bone grafting.Patients and MethodsThe most recent post-operative CBCT of 79 alveolar cleft patients that underwent of anterior iliac crest bone grafting (AICBG) by a single surgeon over...
Sat Oct 26, 2019 16:59
Publication date: Available online 25 October 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Warley Luciano Fonseca Tavares, Francielen Oliveira Fonseca, Lucas Moreira Maia, Vinícius de Carvalho Machado, Nelson Renato França Alves Silva, Gil Moreira Junior, Antônio Paulino Ribeiro SobrinhoAbstractWhen conventional endodontic treatment resources are depleted, endodontic surgery becomes an alternative treatment for apical periodontitis to remove unreachable infected areas and seal...
Sat Oct 26, 2019 16:59
Publication date: Available online 25 October 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Max Ward, Neil Majmundar, Antonios Mammis, Boris PaskhoverAbstractBackgroundTrigeminal neuralgia is a chronic and debilitating syndrome characterized by short paroxysms of lancinating facial pain. Patients may be medically managed; however, in cases of medically refractory trigeminal neuralgia surgical management is often required.ObjectiveTo present and describe the technique for endoscopic...
Sat Oct 26, 2019 16:59
Publication date: Available online 25 October 2019Source: Clinical ImagingAuthor(s): W. James Tom, Xiangdong Xu, Noushin Vahdat, Fiona Cassidy, Lejla AganovicAbstractInflammatory pseudotumors imitate neoplasms on imaging but actually represent focal inflammation. We report a case of follicular pancreatitis, which is a recently recognized distinct form of mass-forming focal chronic pancreatitis pathologically characterized by lymphoid infiltration with abundant reactive germinal centers. In our patient,...
Sat Oct 26, 2019 16:54
Publication date: Available online 26 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Esther L.B. Childers, Lekidelu Taddasse-Heath, Andrea Bonnick, Tammey NaabAbstractThe notable features of ameloblastoma do not typically include prominent vascularity. However, rarely, vascular ameloblastoma has been described under a variety of names. We present a case of vascularized ameloblastoma that had a bloody return on FNA. The English literature had a total of...
Sat Oct 26, 2019 16:54
Publication date: Available online 25 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Ji Rak Kim, Jung Hwan Jo, Jin Woo Chung, Ji Woon ParkAbstractObjectiveTo investigate clinical characteristics and treatment outcomes of patients with temporomandibular disorders (TMD) according to the presence of upper cervical spine abnormalities and craniofacial morphology.Study DesignClinical examinations were conducted on 43 TMD patients. Upper cervical spine characteristics...
Sat Oct 26, 2019 16:54
Publication date: Available online 25 October 2019Source: Pathology - Research and PracticeAuthor(s): Jingrong Qian, Hongxue Meng, Bowen Lv, Jie Wang, Yingying Lu, Shu Zhao, Wenhui LiAbstractToll-like receptor9 (TLR9), a member of pattern recognition receptors, play an important role in tumor immunologic surveillance. However, the clinical impact of TLR9 and programmed cell death-ligand 1 (PD-L1) in peripheral T-cell lymphomas (PTCL) remains unclear. In this study, we examined the expression of TLR9...
Sat Oct 26, 2019 16:53
Abstract Microbeam radiation therapy (MRT), a preclinical form of spatially fractionated radiotherapy, uses an array of microbeams of hard synchrotron X-ray radiation. Recently, compact synchrotron X-ray sources got more attention as they provide essential prerequisites for the translation of MRT into clinics while overcoming the limited access to synchrotron facilities. At the Munich compact light source (MuCLS), one of these novel compact X-ray facilities, a proof of principle...
Sat Oct 26, 2019 03:00
Publication date: Available online 25 October 2019Source: Journal of ProteomicsAuthor(s): Huanying Pang, Wanxin Li, Weijie Zhang, Shihui Zhou, Rowena Hoare, Sean J. Monaghan, Jichan Jian, Xiangmin LinAbstractIt is well known that lysine acetylation (Kace) modification is a common post-translational modification (PTM) that plays an important role in multiple biological and pathological functions in bacteria. However, few studies have focused on lysine acetylation modification in aquatic pathogens...
Sat Oct 26, 2019 16:28
Publication date: Available online 25 October 2019Source: Journal of ProteomicsAuthor(s): MaríaCeleste Ferrari, Micaela Cerletti, Roberto A. Paggi, Christian Troetschel, Ansgar Poetsch, Rosana De CastroGraphical abstract
Sat Oct 26, 2019 16:28
Publication date: Available online 25 October 2019Source: NeuroImageAuthor(s): Mada Hashem, Qiong Zhang, Ying Wu, Thomas W. Johnson, Jeff F. DunnAbstractNon-invasive quantitative imaging of cerebral oxygen metabolism (CMRO2) in small animal models is crucial to understand the role of oxidative metabolism in healthy and diseased brains. In this study, we developed a multimodal method combining near-infrared spectroscopy (NIRS) and MRI to non-invasively study oxygen delivery and consumption in the...
Sat Oct 26, 2019 16:19
Publication date: Available online 25 October 2019Source: Medical Image AnalysisAuthor(s): Gongning Luo, Suyu Dong, Wei Wang, Kuanquan Wang, Shaodong Cao, Clara Tam, Henggui Zhang, Joanne Howey, Pavlo Ohorodnyk, Shuo LiAbstractAccurate and automated cardiac bi-ventricle quantification based on cardiac magnetic resonance (CMR) image is a very crucial procedure for clinical cardiac disease diagnosis. Two traditional and commensal tasks, i.e., bi-ventricle segmentation and direct ventricle function...
Sat Oct 26, 2019 16:16
Key points •Longissimus activity in the lumbar region was measured using indwelling electromyography to characterize the territory of its motor units. •The distribution of motor units in the longissimus pars lumborum muscle was mainly grouped into two distinct regions. •Regional activation of the longissimus pars lumborum was also observed during functional tasks involving trunk movements. •The regional activation of the longissimus pars lumborum muscle may play a role in segmental stabilization...
Fri Oct 25, 2019 19:39
Key points The immediate increase in skeletal muscle blood flow following contraction is greater when the contracting muscle is below vs. above heart level. This has been attributed to muscle pump‐mediated venous emptying and subsequent widening of the arterial to venous pressure gradient which can occur below but not above heart level. However, alternate explanations could include greater rapid onset vasodilatation and/or transmural pressure‐mediated mechanical distension of resistance vessels,...
Fri Oct 25, 2019 15:08
Key points Nod‐like receptors regulate cognition, anxiety, and HPA‐axis activation Nod‐like receptors regulate central and peripheral serotonergic biology Nod‐like receptors are important for maintenance of GI physiology Intestinal epithelial cell expression of Nod1 receptors regulate behaviour Abstract Gut‐brain axis signalling is critical for maintaining health and homeostasis. Stressful life events can impact gut‐brain signalling, leading to altered mood, cognition and intestinal...
Fri Oct 25, 2019 11:33
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