Each month delay increases risk for invasive cancer by 1 percent (Source: The Doctors Lounge - Oncology)
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Key points •Longissimus activity in the lumbar region was measured using indwelling electromyography to characterize the territory of its motor units. •The distribution of motor units in the longissimus pars lumborum muscle was mainly grouped into two distinct regions. •Regional activation of the longissimus pars lumborum was also observed during functional tasks involving trunk movements. •The regional activation of the longissimus pars lumborum muscle may play a role in segmental stabilization...
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Key points The immediate increase in skeletal muscle blood flow following contraction is greater when the contracting muscle is below vs. above heart level. This has been attributed to muscle pump‐mediated venous emptying and subsequent widening of the arterial to venous pressure gradient which can occur below but not above heart level. However, alternate explanations could include greater rapid onset vasodilatation and/or transmural pressure‐mediated mechanical distension of resistance vessels,...
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Key points Nod‐like receptors regulate cognition, anxiety, and HPA‐axis activation Nod‐like receptors regulate central and peripheral serotonergic biology Nod‐like receptors are important for maintenance of GI physiology Intestinal epithelial cell expression of Nod1 receptors regulate behaviour Abstract Gut‐brain axis signalling is critical for maintaining health and homeostasis. Stressful life events can impact gut‐brain signalling, leading to altered mood, cognition and intestinal...
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The aim of this study was to evaluate the fate of preserved aortic root following supracoronary aortic replacement for acute type A aortic dissection.
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Durable mechanical circulatory support device (MCSD) therapy has experienced rapid dissemination in the U.S. Few studies have evaluated geographic patterns of its dissemination based upon patient characteristics that could identify potential variation in its application.
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In this case, we describe an unusual case of dual pathology: i) hypertrophic obstructive cardiomyopathy (HOCM) and ii) aortic root aneurysm. We demonstrate the advantage of a single trans aortic approach to address all components of the HOCM disease. This is illustrated in a video highlighting the main steps of the procedure.
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Although surgical outcomes for anomalous left coronary artery from the pulmonary artery (ALCAPA) are excellent in the modern era with the coronary reimplantantion technique, mortality remains high in Chinese population. This study was undertaken to review the surgical management in our center and assess the midterm outcomes.
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Aneurysm of the main pulmonary trunk (PAA) is a rare but severe complicating factor in patients suffering from pulmonary arterial hypertension (PAH). Many centers consider a PAA as an indication for a heart-lung transplantation. We herein aimed to summarize our institutional experience with a lung-only strategy in this complex group of patients.
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In 2004, a prospective randomized trial demonstrated that, after 3 years, saphenous veins (SV) harvested with a No Touch (NT) technique had a greater patency than radial grafts for coronary bypass surgery. We now report the 8-year follow-up data of this trial.
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The treatment of aortic valve disease in children and adolescents requires an individualized approach to provide a long-term solution with optimal hemodynamic profile. The role of aortic leaflet reconstruction techniques is evolving.
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The Pharmacogenomics Journal, Published online: 25 October 2019; doi:10.1038/s41397-019-0116-yThe effect of genetic and nongenetic factors on warfarin dose variability in Qatari population
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Thank you very much for your interest and inquiry regarding our study (Yeom JS, Buchowski JM, Park KW, et al. Lateral fluoroscopic guide to prevent occipitocervical and atlantoaxial joint violation during C1 lateral mass screw placement. Spine J. 2009;9(7):574-9.). As described in our study, we concur that the shape of the C1 lateral mass is somewhat triangular so that when evaluated on coronal reconstruction images the C1 lateral masses look like a bowtie (Fig. A). Regarding your concern that only...
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We wholeheartedly agree with Klyne and Hodges [1] who emphasized in response to our Perspective [2] that the association between systemic inflammation and musculoskeletal pain is complex. In our Perspective, we called for a prudent interpretation of the literature because multiple confounders influence the association between low-grade systemic inflammation and musculoskeletal pain. A recent systematic review reiterated our viewpoint (“The potential role of confounding factors on the association...
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We read with interest the article by Schipholt et al. 2018 [1] which provides a timely perspective on controlling factors that influence the association between systemic inflammation and musculoskeletal pain. Although we agree with their point, it may not be as simple as it appears.
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We read with great interest the article by Yeom et al. [1]. The authors introduced the concept of the anterior arch target point to help prevent occipitocervical (C0–C1) and atlantoaxial joint violations during C1 lateral mass screw insertion. They defined joint violation as the contact of the screw with the inner margin of the subchondral bone using 2D and 3D computed tomography (CT) images. In the provided Figure (panel A), only the sagittal reconstruction view was provided. The height of the lateral...
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Toxins, Vol. 11, Pages 622: Prey and Venom Efficacy of Male and Female Wandering Spider, Phoneutria boliviensis (Araneae: Ctenidae) Toxins doi: 10.3390/toxins11110622 Authors: Juan Carlos Valenzuela-Rojas Julio César González-Gómez Arie van der Meijden Juan Nicolás Cortés Giovany Guevara Lida Marcela Franco Stano Pekár Luis Fernando García Spiders rely on venom to catch prey and few species are even capable of capturing vertebrates. The majority of spiders are generalist...
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Treatment of bipolar disorder (BD) usually requires drug combinations. Combinations of lithium plus valproic acid (Li/VPA) and lithium plus carbamazepine (Li/CBZ) are used in clinical practice but were not pre...
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Models of collaborative care and consultation liaison propose organizational changes to improve the quality of care for people with common mental disorders, such as anxiety and depression. Some literature sugg...
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Following publication of the original article [1], we have been notified that one of the authors’ names is spelled incorrectly. In this Correction the incorrect and correct author name are shown.
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Every year in the United States 52 MILLION school hours are lost because children have cavities. TWO out of THREE adults have dental disease and we know many of these oral health problems impact systemic body health by exacerbating chronic inflammatory... Read More ›
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Viruses, Vol. 11, Pages 990: Comparative Virological and Pathogenic Characteristics of Avian Influenza H5N8 Viruses Detected in Wild Birds and Domestic Poultry in Egypt during the Winter of 2016/2017 Viruses doi: 10.3390/v11110990 Authors: Yassmin Moatasim Ahmed Kandeil Basma Emad Aboulhoda Rabeh El-Shesheny Maha Alkhazindar Elsayed Tarek AbdElSalam Omnia Kutkat Mina Nabil Kamel Ahmed Nageh El Taweel Ahmed Mostafa Joseph T. Hicks Sary Khaleel Abd elghaffar...
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Viruses, Vol. 11, Pages 989: The Methyltransferase Region of Vesicular Stomatitis Virus L Polymerase Is a Target Site for Functional Intramolecular Insertion Viruses doi: 10.3390/v11110989 Authors: Emmanuel Heilmann Janine Kimpel Stephan Geley Andreas Naschberger Carles Urbiola Tobias Nolden Dorotheé von Laer Guido Wollmann The L-protein of vesicular stomatitis virus (VSV) is a single-chain multi-domain RNA-dependent RNA polymerase. Previously reported attempts of...
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Viruses, Vol. 11, Pages 988: Evolution of a Landscape Phage Library in a Mouse Xenograft Model of Human Breast Cancer Viruses doi: 10.3390/v11110988 Authors: James W. Gillespie Liping Yang Laura Maria De Plano Murray A. Stackhouse Valery A. Petrenko Peptide-displayed phage libraries are billion-clone collections of diverse chimeric bacteriophage particles, decorated by genetically fused peptides built from a random combination of natural amino acids. Studying the molecular...
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Viruses, Vol. 11, Pages 987: Generation and Characterization of a Mouse-Adapted Makona Variant of Ebola Virus Viruses doi: 10.3390/v11110987 Authors: Mable Chan Anders Leung Bryan D. Griffin Robert Vendramelli Nikesh Tailor Kevin Tierney Jonathan Audet Darwyn Kobasa Ebola virus (EBOV) is a zoonotic pathogen that poses a significant threat to public health, causing sporadic yet devastating outbreaks that have the potential to spread worldwide, as demonstrated during...
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Publication date: Available online 25 October 2019Source: Journal of VoiceAuthor(s): Matthias Echternach, Catalina Högerle, Marie Köberlein, Patrick Schlegel, Michael Döllinger, Bernhard Richter, Marie-Anne KainzSummaryIntroductionIt is generally assumed that when singing across the region where registration events for untrained voices occur (the passaggio), singers modify the voice production system in order to avoid changes of voice quality. In this context, it has been postulated that nasalance...
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Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Amina Guenna Holmgren, Niklas Juth, Anna Lindblad, Ann-Christin von VogelsangObjectiveTo investigate the extent to which restraint is used in neurosurgical care, under what circumstances, and how it is documented.MethodsA cross-sectional study with a mixed-methods approach was used to identify neurosurgical inpatients subjected to restraint. The data were collected in 2 phases: (1) a study-specific questionnaire was distributed...
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Publication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Tsinsue Chen, George M. Mastorakos, Kyle I. Swanson, Jennifer M. Eschbacher, Kris A. SmithBackgroundChoroid plexus papillomas (CPPs) are benign World Health Organization grade I tumors that comprise 2%–4% of all brain tumors among children and less than 1% of brain tumors in adults. Most adult cases occur in the fourth ventricle, with only 1 previous report describing an adult patient with a temporal horn CPP.Case DescriptionWe...
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