JCM, Vol. 8, Pages 1801: A Cross-Sectional Study of Hyponatremia Associated with Acute Central Nervous System Infections Journal of Clinical Medicine doi: 10.3390/jcm8111801 Authors: Andy K.H. Lim Sahira Paramaswaran Lucy J. Jellie Ralph K. Junckerstorff Hyponatremia can occur with central nervous system (CNS) infections, but the frequency and severity may depend on the organism and nature of CNS involvement. In this cross-sectional study at a large Australian hospital network...
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JCM, Vol. 8, Pages 1799: Is There Any Role for Super-Extended Limphadenectomy in Advanced Gastric Cancer? Results of an Observational Study from a Western High Volume Center Journal of Clinical Medicine doi: 10.3390/jcm8111799 Authors: Maria Bencivenga Giuseppe Verlato Valentina Mengardo Lorenzo Scorsone Michele Sacco Lorena Torroni Simone Giacopuzzi Giovanni de Manzoni Background: Although the Japan Clinical Oncology Group (JCOG) 9501 trial did not find that prophylactic...
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JCM, Vol. 8, Pages 1800: The Effect of the Intelligent Sepsis Management System on Outcomes among Patients with Sepsis and Septic Shock Diagnosed According to the Sepsis-3 Definition in the Emergency Department Journal of Clinical Medicine doi: 10.3390/jcm8111800 Authors: Juhyun Song Hanjin Cho Dae Won Park Sejoong Ahn Joo Yeong Kim Hyeri Seok Jonghak Park Sungwoo Moon We developed a novel computer program, the Intelligent Sepsis Management System, based on Sepsis-3...
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JCM, Vol. 8, Pages 1798: Immune-Inflammatory Responses in Atherosclerosis: The Role of Myeloid Cells
JCM, Vol. 8, Pages 1798: Immune-Inflammatory Responses in Atherosclerosis: The Role of Myeloid Cells Journal of Clinical Medicine doi: 10.3390/jcm8111798 Authors: Dimitry A. Chistiakov Dmitry A. Kashirskikh Victoriya A. Khotina Andrey V. Grechko Alexander N. Orekhov Inflammation plays a key role in the initiation and progression of atherosclerosis and can be caused by multiple agents, including increased concentration of circulating low-density lipoprotein (LDL) cholesterol....
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JCM, Vol. 8, Pages 1796: Is There Any Improvement of the Coagulation Imbalance in Sickle Cell Disease after Hematopoietic Stem Cell Transplantation? Journal of Clinical Medicine doi: 10.3390/jcm8111796 Authors: Laurence Rozen Denis F. Noubouossie Laurence Dedeken Phu Quoc Lê Alina Ferster Anne Demulder Several components of the clotting system are modified towards hypercoagulability in sickle cell disease (SCD). To date, hematopoietic stem cell transplantation (HSCT) is...
Sat Oct 26, 2019 03:00
JCM, Vol. 8, Pages 1797: Non-Invasive Assessment of Metabolic Adaptation in Paediatric Patients Suffering from Type 1 Diabetes Mellitus Journal of Clinical Medicine doi: 10.3390/jcm8111797 Authors: Phillip Trefz Sibylle C. Schmidt Pritam Sukul Jochen K. Schubert Wolfram Miekisch Dagmar-Christiane Fischer An analysis of exhaled volatile organic compounds (VOC) may deliver systemic information quicker than available invasive techniques. Metabolic aberrations in pediatric...
Sat Oct 26, 2019 03:00
Life, Vol. 9, Pages 82: Detection of Biological Bricks in Space. The Case of Adenine in Silica Aerogel Life doi: 10.3390/life9040082 Authors: Aline Percot Emilie-Laure Zins Amélie Al Araji Anh-Tu Ngo Jacques Vergne Makoto Tabata Akihiko Yamagishi Marie-Christine Maurel Space missions using probes to return dust samples are becoming more frequent. Dust collectors made of silica aerogel blocks are used to trap and bring back extraterrestrial particles for analysis....
Sat Oct 26, 2019 03:00
Metabolites, Vol. 9, Pages 251: Creating a Reliable Mass Spectral–Retention Time Library for All Ion Fragmentation-Based Metabolomics Metabolites doi: 10.3390/metabo9110251 Authors: Ipputa Tada Hiroshi Tsugawa Isabel Meister Pei Zhang Rie Shu Riho Katsumi Craig E. Wheelock Masanori Arita Romanas Chaleckis Accurate metabolite identification remains one of the primary challenges in a metabolomics study. A reliable chemical spectral library increases the confidence...
Sat Oct 26, 2019 03:00
MPs, Vol. 2, Pages 83: High-Throughput Phenotyping Toolkit for Characterizing Cellular Models of Hypertrophic Cardiomyopathy in Vitro Methods and Protocols doi: 10.3390/mps2040083 Authors: Mosqueira Lis-Slimak Denning Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular disease characterised by multifarious hallmarks, a heterogeneous set of clinical manifestations, and several molecular mechanisms. Various disease models have been developed to study this...
Sat Oct 26, 2019 03:00
Microorganisms, Vol. 7, Pages 494: Zymobacter palmae Pyruvate Decarboxylase is Less Effective Than That of Zymomonas mobilis for Ethanol Production in Metabolically Engineered Synechocystis sp. PCC6803 Microorganisms doi: 10.3390/microorganisms7110494 Authors: Lorraine Quinn Patricia Armshaw Tewfik Soulimane Con Sheehan Michael P. Ryan J. Tony Pembroke To produce bioethanol from model cyanobacteria such as Synechocystis, a two gene cassette consisting of genes encoding...
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Microorganisms, Vol. 7, Pages 493: Ciliate Environmental Diversity Can Be Underestimated by the V4 Region of SSU rDNA: Insights from Species Delimitation and Multilocus Phylogeny of Pseudokeronopsis (Ciliophora, Spirotrichea) Microorganisms doi: 10.3390/microorganisms7110493 Authors: Zhan Li Xu Metabarcoding and high-throughput sequencing methods have greatly improved our understanding of protist diversity. Although the V4 region of small subunit ribosomal DNA (SSU-V4 rDNA)...
Sat Oct 26, 2019 03:00
Microorganisms, Vol. 7, Pages 490: The Endophytic Fungus Chaetomium cupreum Regulates Expression of Genes Involved in the Tolerance to Metals and Plant Growth Promotion in Eucalyptus globulus Roots Microorganisms doi: 10.3390/microorganisms7110490 Authors: Javier Ortiz Javiera Soto Alejandra Fuentes Héctor Herrera Claudio Meneses César Arriagada The endophytic strain Chaetomium cupreum isolated from metal-contaminated soil was inoculated in Eucalyptus globulus roots to...
Sat Oct 26, 2019 03:00
Microorganisms, Vol. 7, Pages 491: Crustose Calicioid Lichens and Fungi in Mountain Cloud Forests of Tanzania Microorganisms doi: 10.3390/microorganisms7110491 Authors: Stella Gilbert Temu Sanja Tibell Donatha Damian Tibuhwa Leif Tibell A total of 26 crustose calicioid lichens and fungi were found in Tanzania. Most of them belong to a group of species with wide distributions in cool areas of both hemispheres and occasional occurrence in high mountains at low latitudes. In Tanzania...
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Microorganisms, Vol. 7, Pages 492: Genetic and Phenotypic Characterisation of a Saccharomyces cerevisiae Population of ‘Merwah’ White Wine Microorganisms doi: 10.3390/microorganisms7110492 Authors: Nadine Feghali Warren Albertin Edouard Tabet Ziad Rizk Angela Bianco Giacomo Zara Isabelle Masneuf-Pomarede Marilena Budroni The study of yeast biodiversity represents an important step in the preservation of the local heritage, and this work in particular has an innovative...
Sat Oct 26, 2019 03:00
Molecules, Vol. 24, Pages 3871: Chemical Compositions and Mosquito Larvicidal Activities of Essential Oils from Piper Species Growing Wild in Central Vietnam Molecules doi: 10.3390/molecules24213871 Authors: Le Thi Huong Nguyen Huy Hung Do Ngoc Dai Thieu Anh Tai Vu Thi Hien Prabodh Satyal William N. Setzer Mosquitoes are the deadliest animals on earth and are the vectors of several neglected tropical diseases. Recently, essential oils have emerged as potential renewable,...
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Molecules, Vol. 24, Pages 3872: Discovery of Novel µ-Opioid Receptor Inverse Agonist from a Combinatorial Library of Tetrapeptides through Structure-Based Virtual Screening Molecules doi: 10.3390/molecules24213872 Authors: Poli Dimmito Mollica Zengin Benyhe Zador Stefanucci : Morphine, oxycodone, fentanyl, and other µ-opioid receptors (MOR) agonists have been used for decades in antinociceptive therapies. However, these drugs are associated with numerous...
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Molecules, Vol. 24, Pages 3869: Role of L-Type Amino Acid Transporter 1 (LAT1) for the Selective Cytotoxicity of Sesamol in Human Melanoma Cells Molecules doi: 10.3390/molecules24213869 Authors: Tarapong Srisongkram Natthida Weerapreeyakul Jussi Kärkkäinen Jarkko Rautio Sesamol is effective against melanoma cells with less damage to normal cells. The underlying selective cytotoxicity of sesamol in melanoma vs. non-cancerous cells is undefined. Melanoma cells differ from normal...
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Molecules, Vol. 24, Pages 3870: Replication Stress and Consequential Instability of the Genome and Epigenome Molecules doi: 10.3390/molecules24213870 Authors: Pawlos S. Tsegay Yanhao Lai Yuan Liu Cells must faithfully duplicate their DNA in the genome to pass their genetic information to the daughter cells. To maintain genomic stability and integrity, double-strand DNA has to be replicated in a strictly regulated manner, ensuring the accuracy of its copy number, integrity and epigenetic...
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Molecules, Vol. 24, Pages 3868: The Bioreduction of Selenite under Anaerobic and Alkaline Conditions Analogous to Those Expected for a Deep Geological Repository System Molecules doi: 10.3390/molecules24213868 Authors: Miguel Angel Ruiz-Fresneda Jaime Gomez-Bolivar Josemaria Delgado-Martin Maria del Mar Abad-Ortega Isabel Guerra-Tschuschke Mohamed Larbi Merroun The environmental conditions for the planned geological disposal of radioactive waste —including hyper-alkaline...
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Molecules, Vol. 24, Pages 3867: Hybrid Ionic Silver and Magnetite Microgels Nanocomposites for Efficient Removal of Methylene Blue Molecules doi: 10.3390/molecules24213867 Authors: Atta Gafer Al-Lohedan Abdullah Tawfeek Ezzat The ionic crosslinked 2-acrylamido-2-methylpropane sulfonic acid-co-acrylic acid hydrogel, AMPS/AA and its Ag and Fe3O4 composites were synthesized using an in situ technique. The surface charge, particle sizes, morphology, and thermal stability...
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Molecules, Vol. 24, Pages 3866: Copper Ions Removal from Water using A2B3 Type Hyperbranched Poly(amidoamine) Hydrogel Particles Molecules doi: 10.3390/molecules24213866 Authors: Hojung Choi Youngsik Eom Sanghwa Lee Sang Youl Kim Micrometer-sized hyperbranched poly(amidoamine) (hPAMAM) particles are prepared with a simple A2B3 type Aza–Michael addition reaction between aminoethylpiperazine (AEP) and methylenebisacrylamide (MBA) in an inverse suspension polymerization...
Sat Oct 26, 2019 03:00
MTI, Vol. 3, Pages 70: Prediction of Who Will Be Next Speaker and When Using Mouth-Opening Pattern in Multi-Party Conversation Multimodal Technologies and Interaction doi: 10.3390/mti3040070 Authors: Ryo Ishii Kazuhiro Otsuka Shiro Kumano Ryuichiro Higashinaka Junji Tomita We investigated the mouth-opening transition pattern (MOTP), which represents the change of mouth-opening degree during the end of an utterance, and used it to predict the next speaker and utterance interval...
Sat Oct 26, 2019 03:00
Nanomaterials, Vol. 9, Pages 1529: Controlling the Morphologies of Silver Aggregates by Laser-Induced Synthesis for Optimal SERS Detection Nanomaterials doi: 10.3390/nano9111529 Authors: Longkun Yang Jingran Yang Yuanyuan Li Pan Li Xiaojuan Chen Zhipeng Li Controlling the synthesis of metallic nanostructures for high quality surface-enhanced Raman scattering (SERS) materials has long been a central task of nanoscience and nanotechnology. In this work, silver aggregates...
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Nanomaterials, Vol. 9, Pages 1528: Thermal Stability Evaluation of Polystyrene-Mg/Zn/Al LDH Nanocomposites Nanomaterials doi: 10.3390/nano9111528 Authors: Miguel Ángel De la Rosa-Guzmán Ariel Guzmán-Vargas Nicolás Cayetano-Castro José Manuel Del Río Mónica Corea María de Jesús Martínez-Ortiz A series of samples of Mg/Zn/Al LDHs (layered double hydroxides) materials was prepared by the co-precipitation and urea hydrolysis methods. They were modified with organic surfactants...
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Nanomaterials, Vol. 9, Pages 1527: Editorial for the Special Issue “Characterization of Nanomaterials: Selected Papers from 6th Dresden Nanoanalysis Symposium” Nanomaterials doi: 10.3390/nano9111527 Authors: Ehrenfried Zschech Robert Sinclair Rodrigo Martins Marco Sebastiani Sabrina Sartori More than ever before, materials-driven product innovations in industry and shorter time-to-market introductions for new products require high advancement rates and a tight coupling between...
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Nutrients, Vol. 11, Pages 2587: Gliadin Intake Causes Disruption of the Intestinal Barrier and an Increase in Germ Cell Apoptosis in A Caenorhabditis Elegans Model Nutrients doi: 10.3390/nu11112587 Authors: Hyemin Min Ji-Sun Kim Jiyun Ahn Yhong-Hee Shim Gliadin is a major protein component of gluten and causes gluten toxicity through intestinal stress. We previously showed that gliadin intake induces oxidative stress in the intestine and reduces fertility in a Caenorhabditis...
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Nutrients, Vol. 11, Pages 2586: Efficacy and Mechanism of Polymerized Anthocyanin from Grape-Skin Extract on High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease Nutrients doi: 10.3390/nu11112586 Authors: Meiqi Fan Young-Jin Choi Yujiao Tang Sung Mun Bae Hyun Pil Yang Eun-Kyung Kim We investigated the therapeutic potential of polymerized anthocyanin (PA) on a nonalcoholic fatty liver disease (NAFLD) model in mice. C57BL/6 mice were fed a high-fat diet (HFD) for 8 weeks...
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Nutrients, Vol. 11, Pages 2585: Towards Therapeutic Alternatives for Mercury Neurotoxicity in the Amazon: Unraveling the Pre-Clinical Effects of the Superfruit Açaí (Euterpe oleracea, Mart.) as Juice for Human Consumption Nutrients doi: 10.3390/nu11112585 Authors: Maria Elena Crespo-López Ericks Sousa Soares Barbarella de Matos Macchi Leticia Santos-Sacramento Priscila Yuki Takeda Amanda Lopes-Araújo Ricardo Sousa de Oliveira Paraense José Rogério Souza-Monteiro Marcus...
Sat Oct 26, 2019 03:00
Nutrients, Vol. 11, Pages 2584: Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice Nutrients doi: 10.3390/nu11112584 Authors: Lucia A. Seale Vedbar S. Khadka Mark Menor Guoxiang Xie Ligia M. Watanabe Alexandru Sasuclark Kyrillos Guirguis Herena Y. Ha Ann C. Hashimoto Karolina Peplowska Maarit Tiirikainen Wei Jia Marla J. Berry Youping Deng Selenium is a nonmetal trace element that is critical...
Sat Oct 26, 2019 03:00
Nutrients, Vol. 11, Pages 2583: The Association of Disease Activity, BMI and Phase Angle with Vitamin D Deficiency in Patients with IBD Nutrients doi: 10.3390/nu11112583 Authors: Maria Chiara Mentella Franco Scaldaferri Marco Pizzoferrato Antonio Gasbarrini Giacinto Abele Donato Miggiano Hypovitaminosis D is frequently present in inflammatory bowel disease (IBD) with a higher incidence in Crohn’s disease (CD) than in Ulcerative Colitis (UC). Given the involvement...
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Nutrients, Vol. 11, Pages 2582: The Association between Sleep Duration and Metabolic Syndrome: The NHANES 2013/2014 Nutrients doi: 10.3390/nu11112582 Authors: Abbas Smiley David King Aurelian Bidulescu Background: We aimed to assess the association of sleep with metabolic syndrome in the 2013/2014 National Health and Nutrition Examination Survey (NHANES). Methods: Sample size included 2737 out of 2013 and 2014 NHANES surveys. Cross-sectional study of metabolic syndrome and sleep...
Sat Oct 26, 2019 03:00
Pharmaceuticals, Vol. 12, Pages 162: Hydroxypyridinone-Diamine Hybrids as Potential Neuroprotective Agents in the PC12 Cell-Line Model of Alzheimer's Disease Pharmaceuticals doi: 10.3390/ph12040162 Authors: Lohou Sasaki Boullier Duplantier Sonnet There is an urgent need to propose effective treatments for Alzheimer’s disease (AD). Although the origin of the disease is poorly understood, several therapeutic options have been proposed. The new therapeutic approaches...
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Pharmaceuticals, Vol. 12, Pages 161: Synthesis of Curcumin Derivatives and Analysis of Their Antitumor Effects in Triple Negative Breast Cancer (TNBC) Cell Lines Pharmaceuticals doi: 10.3390/ph12040161 Authors: Paola Maria Bonaccorsi Manuela Labbozzetta Anna Barattucci Tania Maria Grazia Salerno Paola Poma Monica Notarbartolo We analyzed antitumor effects of a series of curcumin analogues. Some of them were obtained by reaction of substitution involving the two phenolic...
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Pharmaceutics, Vol. 11, Pages 553: Decellularized Lymph Node Scaffolding as a Carrier for Dendritic Cells to Induce Anti-Tumor Immunity Pharmaceutics doi: 10.3390/pharmaceutics11110553 Authors: Hung-Jun Lin Weu Wang Yi-You Huang Wei-Tsen Liao Ting-Yu Lin Shyr-Yi Lin Der-Zen Liu In recent decades, the decellularized extracellular matrix (ECM) has shown potential as a promising scaffold for tissue regeneration. In this study, an organic acid decellularized lymph node...
Sat Oct 26, 2019 03:00
Plants, Vol. 8, Pages 455: Supercritical Carbon Dioxide Antisolvent Fractionation for the Sustainable Concentration of Lavandula luisieri (Rozeira) Riv.- Mart Antimicrobial and Antioxidant Compounds and Comparison with Its Conventional Extracts Plants doi: 10.3390/plants8110455 Authors: Carlota Giménez-Rota Susana Lorán Ana M. Mainar María J. Hernáiz Carmen Rota Lavandula stoechas subsp. luisieri is a Spanish subspecies from the Lamiaceae family. Its essential oil has been...
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Plants, Vol. 8, Pages 453: Evaluation of In Vitro Solar Protection Factor (SPF), Antioxidant Activity, and Cell Viability of Mixed Vegetable Extracts from Dirmophandra mollis Benth, Ginkgo biloba L., Ruta graveolens L., and Vitis vinífera L. Plants doi: 10.3390/plants8110453 Authors: Letícia Caramori Cefali Janaina Artem Ataide Ana Rita Fernandes Elena Sanchez-Lopez Ilza Maria de Oliveira Sousa Mariana Cecchetto Figueiredo Ana Lucia Tasca Gois Ruiz Mary Ann Foglio Priscila...
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Plants, Vol. 8, Pages 454: Phytochemical Screening, Antibacterial Activity and Heavy Metal Analysis of Ethnomedicinal Recipes and Their Sources Used Against Infectious Diseases Plants doi: 10.3390/plants8110454 Authors: Nasir Mahmood Ruqia Nazir Muslim Khan Rashid Iqbal Muhammad Adnan Mohib Ullah Hongyi Yang Plants are a rich source of secondary metabolites that have been found to have medicinal properties. The present study was conducted to evaluate the phytochemical...
Sat Oct 26, 2019 03:00
Resources, Vol. 8, Pages 168: Geoheritage as a Tool for Environmental Management: A Case Study in Northern Malta (Central Mediterranean Sea) Resources doi: 10.3390/resources8040168 Authors: Lidia Selmi Paola Coratza Ritienne Gauci Mauro Soldati The recognition, selection and quantitative assessment of sites of geological and geomorphological interest are fundamental steps in any environmental management focused on geoconservation and geotourism promotion. The island of Malta,...
Sat Oct 26, 2019 03:00
Toxins, Vol. 11, Pages 622: Prey and Venom Efficacy of Male and Female Wandering Spider, Phoneutria boliviensis (Araneae: Ctenidae) Toxins doi: 10.3390/toxins11110622 Authors: Juan Carlos Valenzuela-Rojas Julio César González-Gómez Arie van der Meijden Juan Nicolás Cortés Giovany Guevara Lida Marcela Franco Stano Pekár Luis Fernando García Spiders rely on venom to catch prey and few species are even capable of capturing vertebrates. The majority of spiders are generalist...
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