Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

Learning Health Systems and the Future of Clinical Research

Pediatric surgeons are collectively passionate about prioritizing the healthcare needs of children. We contend that this passion is deeply ingrained in how we drive clinical care and influence scientific discovery. Thus, the future of clinical research in our field will be deeply embedded in our history as a “patient-centric” profession. Service to pediatric patients requires an understanding of their needs and expectations, and designing research that acknowledges both. In this article we detail...

Journal of Pediatric Surgery

13h

A Standardized Technique of Laparoscopic Placement of Peritoneal Dialysis Catheter with Omentectomy and Closure of Patent Processus Vaginalis: A 3-in-1 Minimally Invasive Surgical Approach in Children

Omental wrapping is a common cause for catheter failure in children on peritoneal dialysis (PD). Previous studies are conflicting in the benefits of omentectomy.

Journal of Pediatric Surgery

13h

Reply to Letter to the Editor

We appreciate the letter from Dr. Davenport and Dr. Macdonald from Kings College Hospital regarding our single center 26-year experience and long-term outcomes for patients who underwent HPE for biliary atresia. The aim of our study was to determine perioperative risk factors associated with progression to liver transplantation following HPE [1]. Our results, similar to those of Shneider et.al [2], showed total bilirubin at 3 months following HPE was the strongest predictor of need for transplantation.

Journal of Pediatric Surgery

13h

A single institution experience of Eppikajutsuto for the treatment of lymphatic malformations in children

Eppikajutsuto (TJ-28) is an herbal medicine recently reported to be effective in treating lymphatic malformations (LMs). We report our experience concerning the clinical efficacy of TJ-28 for LMs.

Journal of Pediatric Surgery

13h

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Journal of Stroke and Cerebrovascular Diseases

Successful Cesarean Section Deliveries in a Patient with a History of Developmental Venous Anomaly-Induced Hemorrhage

While hemorrhage can occur because of developmental venous anomalies (DVAs), there is no established opinion concerning their association with pregnancy and childbirth. In the present report, we discuss the case of a now 39-year-old woman with DVA in whom pregnancy and childbirth were successful. When she was 28, she experienced disturbance of consciousness and paralysis on the left side of the body, and brain computed tomography revealed cerebral hemorrhage coupled with subarachnoid hemorrhage.

Journal of Stroke and Cerebrovascular Diseases

12h

Computed Tomography Angiogram Derived From Computed Tomography Perfusion Done With Low Iodine Volume Protocol Preserves Diagnostic Yield for Middle Cerebral Artery-M2 Occlusions

Background: Computed tomography angiogram (CTA) derived from computed tomography perfusion (CTP) has been proposed to avoid addition of separate CT perfusion protocol for selection of large vessel occlusion in acute stroke patients. Previous studies have validated this technique for proximal large vessel occlusions. In this study, we test reliability for identifying M2 occlusions on CTA derived from CTP. Methods: Through a retrospective search of the institutional thrombectomy database, we identified...

Journal of Stroke and Cerebrovascular Diseases

12h

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JoVE: Journal of Visualized Experiments

Laser-Induced Fluorescence Emission (L.I.F.E.) as Novel Non-Invasive Tool for In-Situ Measurements of Biomarkers in Cryospheric Habitats

Carbon fluxes in the cryosphere are hardly assessed yet but are crucial regarding climate change. Here we show a novel prototype device that captures the phototrophic potential in supraglacial environments based on laser-induced fluorescence emission (L.I.F.E.) technology offering high spectral and spatial resolution data under in situ conditions.

JoVE: Journal of Visualized Experiments

14h

Primary Culture of Neurons Isolated from Embryonic Mouse Cerebellum

Conducting in vitro experiments to reflect in vivo conditions as adequately as possible is not an easy task. The use of primary cell cultures is an important step toward understanding cell biology in a whole organism. The provided protocol outlines how to successfully grow and culture embryonic mouse cerebellar neurons.

JoVE: Journal of Visualized Experiments

15h

A Training and Testing System for Performing Vascular Reconstruction In Vitro

Here we present a training and testing system where a trainee can complete manual vascular reconstruction in vitro individually using a magnetic anchoring technique. The system can also be used to test the quality of reconstruction.

JoVE: Journal of Visualized Experiments

16h

Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat

Here, we present a protocol to establish a replicable conductive hearing loss induction via surgical tympanic membrane puncture and verification by otoscope visualization and behavioral assessment by clap startle.

JoVE: Journal of Visualized Experiments

17h

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Κυριακή 27 Οκτωβρίου 2019

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