Trans-spinal direct current stimulation (tsDCS) is a non-invasive technique with promising neuromodulatory effects on spinal cord (SC) circuitry. Computational studies are essential to guide effective tsDCS pr...
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Abstract Advance care planning (ACP) has been identified as a fundamental part of every patient’s total health care plan and is actively supported by a number of health care organizations. Despite these endorsements, however, having advance care planning conversations has not come easily for physicians. Training future physicians should include practical ways to address this issue. Fifty physicians at an oncology hospital, who were identified as having the most ACP conversations,...
Abstract The implementation of electronic health records is viewed as an effective method to increase safety, efficiency, and effectiveness of nursing care. Nurses are crucial to the successful adoption of electronic health records. The purpose of this study is to assess oncology nurses’ attitude toward electronic health records in Jordan. A quantitative cross-sectional survey design was used, in which 271 nurses completed the Nurses’ Attitudes Towards Computerization questionnaire....
Abstract In 2013, the US Preventive Services Task Force recommended low-dose computed tomography screening for smokers at high risk of lung cancer; however, use remains low. Efforts to promote lung cancer screening need to consider how receptive this population is to preventive healthcare and cancer screening. In addition, because of demonstrated heterogeneity in behaviors by smoking status, interventions may need to differ among eligible high-risk subgroups. To assess the engagement...
Abstract The purpose of the study is to describe oncologists’ perceptions and opinions about patient eligibility, guidelines, and barriers for use of granulocyte colony-stimulating factor (G-CSF), overall and stratified by their affiliation with the Oncology Care Model (OCM). In May 2018, we invited and recruited practicing US oncologists from a national database for an online survey. Level of agreement was identified using a seven-point scale, ranging from strongly disagree to...
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Publication date: Available online 25 October 2019Source: Seminars in Cancer BiologyAuthor(s): Francesco Fabbri, Samanta Salvi, Sara BravacciniAbstractTriple negative breast cancer (TNBC) is one of the most biologically aggressive and very often lethal breast disease. It is one of the most puzzling women malignancies, and it currently appears not to be a good candidate to a standardized, unanimously accepted and sufficiently active therapeutic strategy. Fast proliferating and poorly differentiated,...
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Abstract Background The association between telomerase reverse transcriptase (TERT) promoter mutations and some clinical behaviors in thyroid cancer remains controversial and requires additional investigation. This study aimed to evaluate the association between TERT promoter mutations and clinical behaviors (including clinicopathological features and prognosis) in differentiated thyroid carcinomas (DTC). ...
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Abstract Objective To estimate the maternity-related cost of health care services in women with and without severe maternal morbidity (SMM). Methods Women with a live inpatient birth in the calendar year 2013 were identified in the MarketScan® Commercial and Medicaid health insurance claims databases. Costs were defined as the amounts paid by insurers plus...
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Publication date: Available online 25 October 2019Source: Archives of Oral BiologyAuthor(s): S. Rajan, A. Ljunggren, D.J. Manton, A.E Björkner, M. McCulloughAbstractObjectiveDescription of the odontoblast lifecycle, an overview of the known complex molecular interactions that occur when the health of the dental pulp is challenged and the current and future management strategies on vital and non-vital teeth.MethodsA literature search of the electronic databases included MEDLINE (1966-April 2019),...
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Publication date: October 2019Source: Current Opinion in Neurobiology, Volume 58Author(s): Simon Musall, Anne E Urai, David Sussillo, Anne K ChurchlandWith the increasing acquisition of large-scale neural recordings comes the challenge of inferring the computations they perform and understanding how these give rise to behavior. Here, we review emerging conceptual and technological advances that begin to address this challenge, garnering insights from both biological and artificial neural networks....
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Abstract In this paper, we present a short review of some well-known image codecs in the literature and summarize a systematic study that determines the root cause of some puzzling observations in image compression experiments. Moreover, we propose a methodology to determine whether an image is genuine or not, meaning that whether or not a given image has been compressed and decompressed before and by which codec. In image compression class projects, students may observe some strange...
Abstract In order to effectively evaluate the quality of stereoscopic images, we propose a no-reference stereoscopic image quality assessment (SIQA) method. Firstly, considering the characteristics of binocular fusion, binocular rivalry, and binocular suppression of human visual system, we propose a new color cyclopean image which is suitable for symmetric and asymmetric distortion images. And then, based on the importance of the disparity map, the enhanced image is generated...
Abstract Multi-level thresholding is one of the most popular techniques in image segmentation. However, selecting the optimal thresholds with high accuracy and efficiency is still challenging. In this paper, a novel multi-level thresholding method using between-class variance (Otsu) based on an improved invasive weed optimization algorithm (FIWO) is proposed. In the FIWO algorithm, the forking technique of the lightning search algorithm is introduced to guarantee the quality of...
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Publication date: Available online 25 October 2019Source: Journal of Oral BiosciencesAuthor(s): Jagadish Kudkuli, Riaz Abdulla, P.D. Rekha, S.D. Sharma, Omprakash GurjarAbstractObjectiveTo study the effect of radiation therapy on the structural and elemental composition of permanent teeth enamel in vitro.MethodsSections from 21 noncarious healthy human teeth were exposed to a cumulative radiation dose of 20 - 80 Gy. The sections were subjected to electron dispersive spectroscopy (EDS), Fourier transform...
Publication date: Available online 25 October 2019Source: Journal of Oral BiosciencesAuthor(s): Shuho Arakawa, Mogami Inoue, Rina Kinouchi, Shiori Morizumi, Manaka Yamaguchi, Yoshihito Shimazu, Mamoru TakedaAbstractObjectivesGenistein, a dietary constituent, modulates voltage-dependent and ligand-gated ionic channels, suggesting that it could also attenuate inflammatory hyperalgesia. However, the mechanism underlying how genistein affects inflammation-induced hyperexcitability of nociceptive neurons...
Publication date: Available online 25 October 2019Source: Journal of Oral BiosciencesAuthor(s): Kei Manabe, Mayumi Yakeishi, Wakako Sakaguchi, Juri Saruta, Keiichi TsukinokiAbstractObjectivesPeripheral odontogenic fibroma (POF) is a relatively rare odontogenic tumor of the gingiva. Although its histological differential diagnosis from fibrous epulis (FE) is important, no study has reported the differences in their expression of immunohistochemical markers. Here, we compared the expression of tumor...
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Abstract Atherosclerosis is a major cause of mortalities and morbidities worldwide. It is associated with hyperlipidemia and inflammation, and become chronic by triggering metabolites in different metabolic pathways. Disturbance in the human gut microbiota is now considered a critical factor in the atherosclerosis. Trimethylamine-N-oxide (TMAO) attracts attention and is regarded as a vital contributor in the development of atherosclerosis. TMAO is generated from its dietary precursors...
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Abstract Background Protein arginine methyltransferase-1 (PRMT1) is associated with the progression of various tumor types and the process of epithelial to mesenchymal transition (EMT). However, the expression of PRMT1 in renal cell tumors (RCT) is unknown. Methods We evaluated PRMT1 immunohistochemical (IHC) expression on tissue microarray...
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Publication date: Available online 25 October 2019Source: American Journal of OtolaryngologyAuthor(s): K.K. Bommakanti, W.J. Moss, R.A. Weisman, P.A. WeissbrodAbstractObjectivesThe objective of this study is to analyze and report the institution's experience using the Enseal bipolar tissue sealing device to perform endoscopic Zenker's diverticulotomy. Safety and early functional outcomes are presented as primary endpoints of the study.Materials & methodsThis is a retrospective study of consecutive...
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Abstract Rigid polyurethane (PU) foams are widely used in modern life owing to excellent strength and weight carrying capacity. Most of the rigid PU foams in the market are based on polypropylene oxide (PPO) and methylene diphenyl diisocyanate. Amine catalysts, especially tertiary amines, are used to balance both the gelling and gas-foaming reactions, responsible for foam formation. The objective of present work is to prepare rigid PU foams from PPO based polyol and 4,4′- methylene...
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AIM To investigate the association between genetic polymorphisms in ATG16L1 and IRGM genes with Crohn's disease (CD) in Malaysian patients. METHODS A total of 335 subjects were recruited, including 85 CD patients and 250 unrelated healthy controls, and informed consent was obtained. Genomic DNA was extracted via a conventional phenol‐chloroform extraction method. Genotyping of six SNPs in ATG16L1 and IRGM genes was conducted via TaqMan SNP genotyping assays. The association of the SNPs with...
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Abstract Background We investigated the association between the pretreatment quality of life (QOL) and overall survival (OS) in patients with urothelial carcinoma (UC), as the influence of pretreatment QOL on prognosis remains unclear in patients with localized and metastatic UC. Methods Between June 2013 and May 2019, we retrospectively investigated 205...
18h
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Abstract Two-dimensional HPLC (2D-HPLC) recently has received great attention due to providing high resolving power and higher peak capacities than that of 1D-HPLC, especially dealing with a wide spectrum of sample matrices containing several components. In this work, an on-line heart-cutting two-dimensional liquid chromatography (2D-LC) method was developed using monolithic columns coupled with reversed-phase liquid chromatography (RPLC). 2D-HPLC was successfully carried out...
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Publication date: Available online 25 October 2019Source: Radiotherapy and OncologyAuthor(s): Wei Wei, Ke Wang, Zhenyu Liu, Kaibing Tian, Liang Wang, Jiang Du, Junpeng Ma, Shuo Wang, Longfei Li, Rui Zhao, Luo Cui, Zhen Wu, Jie TianAbstractBackground and purposeWe used radiomic analysis to establish a radiomic signature based on anatomical magnetic resonance imaging (MRI) sequences and explore its effectiveness as a novel prognostic biomarker for skull base chordoma (SBC).Materials and methodsIn this...
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Publication date: Available online 25 October 2019Source: Journal of VoiceAuthor(s): Matthias Echternach, Catalina Högerle, Marie Köberlein, Patrick Schlegel, Michael Döllinger, Bernhard Richter, Marie-Anne KainzSummaryIntroductionIt is generally assumed that when singing across the region where registration events for untrained voices occur (the passaggio), singers modify the voice production system in order to avoid changes of voice quality. In this context, it has been postulated that nasalance...
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Publication date: Available online 25 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Rongzhou He, Yanchen Ye, Zilun Li, Yu Jiang, Yonghui Li, Yunyan Liu, Kangjie Wang, Chen Yao
Publication date: Available online 25 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Axel Haine, Martin J. Schmid, Marc Schindewolf, Armando Lenz, Sarah M. Bernhard, Heinz Drexel, Iris Baumgartner, Jörn F. DopheideObjectivesInformation on performance of different stent platforms in endovascular revascularisation of femoropopliteal lesions is controversial and scarce.MethodsInterwoven nitinol (INS, Supera) were compared with drug eluting (DES, Zilver PTx) stents...
Publication date: Available online 25 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Christos Liapis, Efthymios D. Avgerinos, Hans-Henning Eckstein
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Publication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Nagla A. El-Shitany, Basma G. EidAbstractCellular inflammation has been recognized as the leading factor in numerous diseases, causing either cell death, organ-specific damage, or genesis of different cancers. Icariin, a flavonol glucoside, extracted from Herba Epimedii, offers various pharmacological activities, including reducing inflammation and an antioxidant effect. We aimed to evaluate the anti-inflammatory...
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Publication date: January 2020Source: Magnetic Resonance Imaging, Volume 65Author(s): Saeed Jerban, Eric Y. Chang, Jiang DuAbstractOsteoarthritis (OA) is a very common disease that affects the human knee joint, particularly the articular cartilage and meniscus components which are regularly under compressive mechanical loads. Early-stage OA diagnosis is essential as it allows for timely intervention. The primary non-invasive approaches currently available for OA diagnosis include magnetic resonance...
Publication date: January 2020Source: Magnetic Resonance Imaging, Volume 65Author(s): Ponnada A. Narayana, Ivan Coronado, Sheeba J. Sujit, Xiaojun Sun, Jerry S. Wolinsky, Refaat E. GabrAbstractBackgroundMagnetic resonance images with multiple contrasts or sequences are commonly used for segmenting brain tissues, including lesions, in multiple sclerosis (MS). However, acquisition of images with multiple contrasts increases the scan time and complexity of the analysis, possibly introducing factors...
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Publication date: Available online 25 October 2019Source: Brain StimulationAuthor(s): Fuminari Kaneko, Eriko Shibata, Megumi Okawada, Takashi NagamineAbstractBackgroundThe ability to manipulate the excitability of the network between the inferior parietal lobule (IPL) and primary motor cortex (M1) may have clinical value.ObjectiveTo investigate the possibility of inducing long-lasting changes in M1 excitability by applying quadripulse transcranial magnetic stimulation (QPS) to the IPL, and to ascertain...
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Publication date: Available online 25 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Natale Ferreira Gontijo-de-Amorim, Luiz Charles-de-Sá, Gino Rigotti
Publication date: Available online 25 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Lee L.Q. Pu
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Publication date: Available online 25 October 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Elena Crestani, Hani Harb, Louis-Marie Charbonnier, Jonathan Leirer, Alison Motsinger-Reif, Rima Rachid, Wanda Phipatanakul, Rima Kaddurah-Daouk, Talal A. ChatilaAbstractBackgroundFood allergy (FA) affects an increasing proportion of children. for reasons that remain obscure. Novel disease biomarkers and curative treatment options are strongly needed.ObjectiveTo apply untargeted metabolomic...
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Publication date: Available online 25 October 2019Source: Trends in Cell BiologyAuthor(s): Noa Roitenberg, Ehud CohenThe proteostasis network (PN) is a nexus of mechanisms that act in concert to maintain the integrity of the proteome. Efficiency of the PN declines with age, resulting in the accumulation of misfolded proteins, and in some cases in the development of neurodegenerative disorders. Thus, maintaining an active and efficient PN through the late stages of life could delay or prevent neurodegeneration....
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