Antioxidants, Vol. 8, Pages 513: Modulation of Reactive Oxygen Species in Health and Disease Antioxidants doi: 10.3390/antiox8110513 Authors: Solomon Habtemariam In diverse living organisms, signaling within the cell, chemical communication between cells or simply the fate of cells to survive or die is largely dependent on the intricate balance of control mechanisms related to reactive oxygen species (ROS)[...]
Sat Oct 26, 2019 03:00
Arts, Vol. 8, Pages 145: Australian Indigenous Art Centres Online: A Multi-Purpose Cultural Tourism Framework Arts doi: 10.3390/arts8040145 Authors: Vett In early 2019, Australia’s Northern Territory (NT) government announced the $106 million funding and promotion of a new state-wide Territory Arts Trail featuring Indigenous art and culture under the banner “The World’s biggest art gallery is the NT.” Some of the destinations on the Arts Trail...
Sat Oct 26, 2019 03:00
Arts, Vol. 8, Pages 144: Three Women Sharing a Mantle in 6th Century BCE Greek Vase-Painting: Plurality, Unity, Family, and Social Bond Arts doi: 10.3390/arts8040144 Authors: Toillon The motif of three women sharing the same mantle is pictured on about a dozen vases dating from the first half of the sixth century BCE. Among these vases, the so-called “François Vase” and a dinos signed by Sophilos (now in London, British Museum) are of particular interest....
Sat Oct 26, 2019 03:00
Biomedicines, Vol. 7, Pages 84: Outcomes of Gallic Acid on Alternariol Induced Cyto-Morphic and Genotoxic In Vivo Changes in Parotid Gland: 4-HNE Incorporated Biomedicines doi: 10.3390/biomedicines7040084 Authors: Mai A. Samak Ahmed Elshatory Eman M. Mohamed Alternaria toxins are emerging mycotoxins that gained considerable interest with increasing evidence of their existence and toxicological properties. There is limited research and insufficient data about their in vivo hazardous...
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Biomolecules, Vol. 9, Pages 659: Plant Polyphenols Inhibit Functional Amyloid and Biofilm Formation in Pseudomonas Strains by Directing Monomers to Off-Pathway Oligomers Biomolecules doi: 10.3390/biom9110659 Authors: Zahra Najarzadeh Hossein Mohammad-Beigi Jannik Nedergaard Pedersen Gunna Christiansen Thorbjørn Vincent Sønderby Seyed Abbas Shojaosadati Dina Morshedi Kristian Strømgaard Georg Meisl Duncan Sutherland Jan Skov Pedersen Daniel E. Otzen Self-assembly...
Sat Oct 26, 2019 03:00
Cancers, Vol. 11, Pages 1664: IL-33 Promotes CD11b/CD18-Mediated Adhesion of Eosinophils to Cancer Cells and Synapse-Polarized Degranulation Leading to Tumor Cell Killing Cancers doi: 10.3390/cancers11111664 Authors: Sara Andreone Francesca Spadaro Carla Buccione Jacopo Mancini Antonella Tinari Paola Sestili Adriana Rosa Gambardella Valeria Lucarini Giovanna Ziccheddu Isabella Parolini Cristiana Zanetti Maria Teresa D’Urso Adele De Ninno Luca Businaro...
Sat Oct 26, 2019 03:00
Cancers, Vol. 11, Pages 1662: Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer Cancers doi: 10.3390/cancers11111662 Authors: Adriana C. Gamboa Joshua H. Winer The management of peritoneal metastases from gastric cancer origin has evolved considerably over the last three decades with the establishment of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) as efficacious therapies in carefully selected patients. Other...
Sat Oct 26, 2019 03:00
Cancers, Vol. 11, Pages 1663: The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia Cancers doi: 10.3390/cancers11111663 Authors: Arne Velthaus Kerstin Cornils Jan K. Hennigs Saskia Grüb Hauke Stamm Daniel Wicklein Carsten Bokemeyer Michael Heuser Sabine Windhorst Walter Fiedler Jasmin Wellbrock Leukemia-initiating cells reside within the bone marrow in specialized niches where they undergo complex interactions with...
Sat Oct 26, 2019 03:00
Cancers, Vol. 11, Pages 1661: Should All Patients With HR-Positive HER2-Negative Metastatic Breast Cancer Receive CDK 4/6 Inhibitor As First-Line Based Therapy? A Network Meta-Analysis of Data from the PALOMA 2, MONALEESA 2, MONALEESA 7, MONARCH 3, FALCON, SWOG and FACT Trials Cancers doi: 10.3390/cancers11111661 Authors: Valentina Rossi Paola Berchialla Diana Giannarelli Cecilia Nisticò Gianluigi Ferretti Simona Gasparro Michelangelo Russillo Giovanna Catania Leonardo...
Sat Oct 26, 2019 03:00
Cancers, Vol. 11, Pages 1659: Circulating Tumor Cells in Pancreatic Cancer: Current Perspectives Cancers doi: 10.3390/cancers11111659 Authors: Verena Martini Sylvia Timme-Bronsert Stefan Fichtner-Feigl Jens Hoeppner Birte Kulemann Pancreatic cancer is the fourth leading cause of cancer-related death in the USA and Europe; early symptoms and screenings are lacking, and it is usually diagnosed late with a poor prognosis. Circulating tumor cells (CTCs) have been promising new...
Sat Oct 26, 2019 03:00
Cancers, Vol. 11, Pages 1658: Toxicity Profiles of Fractionated Radiotherapy, Contemporary Stereotactic Radiosurgery, and Transsphenoidal Surgery in Nonfunctioning Pituitary Macroadenomas Cancers doi: 10.3390/cancers11111658 Authors: Chia-Lun Chang Kevin Sheng-Po Yuan Alexander T.H. Wu Szu-Yuan Wu Background: Here, we compared the toxicity profiles of contemporary stereotactic radiosurgery (SRS), modern fractionated radiotherapy (FRT), and transsphenoidal surgery used to treat...
Sat Oct 26, 2019 03:00
Cancers, Vol. 11, Pages 1657: Novel Antrodia cinnamomea Extract Reduced Cancer Stem-Like Phenotype Changes and Resensitized KRAS-Mutant Colorectal Cancer via a MicroRNA-27a Pathway Cancers doi: 10.3390/cancers11111657 Authors: Tsung-Jen Lin Kuo-Chu Lai An-Sheng Lee Chien-Hsin Chang Chiung-Lin Liu Ching-Hu Chung Colorectal cancer (CRC) is one of the most common causes of death in Taiwan. Previous studies showed that Antrodia cinnamomea (AC) can treat poisoning, diarrhea,...
Sat Oct 26, 2019 03:00
Cancers, Vol. 11, Pages 1660: Targeting Apoptotic Pathways in Acute Myeloid Leukaemia Cancers doi: 10.3390/cancers11111660 Authors: Jonathan R. Sillar Anoop K. Enjeti Acute Myeloid Leukaemia is a devastating disease that continues to have a poor outcome for the majority of patients. In recent years, however, a number of drugs have received FDA approval, following on from successful clinical trial results. This parallels the characterization of the molecular landscape of Acute Myeloid...
Sat Oct 26, 2019 03:00
Cells, Vol. 8, Pages 1324: The Role of Gut-Derived Microbial Antigens on Liver Fibrosis Initiation and Progression Cells doi: 10.3390/cells8111324 Authors: Dishen Chen Thanh H. Le Haleh Shahidipour Scott A. Read Golo Ahlenstiel Intestinal dysbiosis has recently become known as an important driver of gastrointestinal and liver disease. It remains poorly understood, however, how gastrointestinal microbes bypass the intestinal mucosa and enter systemic circulation to enact an...
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Climate, Vol. 7, Pages 125: An Innovative Damage Model for Crop Insurance, Combining Two Hazards into a Single Climatic Index Climate doi: 10.3390/cli7110125 Authors: Dorothée Kapsambelis David Moncoulon Jean Cordier Extreme weather events have strong impacts on agriculture and crop insurance. In France, drought (2003, 2011, 2017, and 2018) and excess of water (2016) are considered the most significant events in terms of economic losses. The crop (re)insurance industry must estimate...
Sat Oct 26, 2019 03:00
Diagnostics, Vol. 9, Pages 165: Breast Cancer Diagnosis Using an Efficient CAD System Based on Multiple Classifiers Diagnostics doi: 10.3390/diagnostics9040165 Authors: Ragab Sharkas Attallah Breast cancer is one of the major health issues across the world. In this study, a new computer-aided detection (CAD) system is introduced. First, the mammogram images were enhanced to increase the contrast. Second, the pectoral muscle was eliminated and the breast was suppressed from the...
Sat Oct 26, 2019 03:00
EJIHPE, Vol. 10, Pages 159-172: Occupational Self-Efficacy and Psychological Capital Amongst Nursing Students: A Cross Sectional Study Understanding the Malleable Attributes for Success European Journal of Investigation in Health, Psychology and Education doi: 10.3390/ejihpe10010014 Authors: Daniel Terry Blake Peck Andrew Smith Hoang Nguyen With a predicted shortfall in the worldwide nursing workforce, efforts to understand attributes that influence attrition and workforce longevity...
Sat Oct 26, 2019 03:00
IJERPH, Vol. 16, Pages 4138: Phenomenological and Thermodynamic Model of Gas Exchanges in the Placenta during Pregnancy: A Case Study of Intoxication of Carbon Monoxide International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214138 Authors: Juliana Rangel Cenzi Cyro Albuquerque Carlos Eduardo Keutenedjian Mady The present work simulates the transport of oxygen, carbon dioxide, and carbon monoxide between a fetus’s circulatory system and...
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IJERPH, Vol. 16, Pages 4136: Determinants of Smoking Status in a Sample of Outpatients Afferent to a Tertiary Referral Hospital International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214136 Authors: Alessandro Radaeli Matteo Nardin Danila Azzolina Mario Malerba The identification of determinants of attempts to quit smoking and quitting smoking success is crucial for effective smoking prevention and/or cessation programs. Thus, here we have conducted...
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IJERPH, Vol. 16, Pages 4137: The Analysis of Bifenox and Dichlobenil Toxicity in Selected Microorganisms and Human Cancer Cells International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214137 Authors: Agata Jabłońska-Trypuć Urszula Wydro Lluis Serra-Majem Elżbieta Wołejko Andrzej Butarewicz Bifenox and Dichlobenil belong to the commonly used in Poland in agriculture group of herbicides and their residues are often detected in the environment....
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IJERPH, Vol. 16, Pages 4135: Maternal Mental Illness Is Associated with Adverse Neonate Outcomes: An Analysis of Inpatient Data International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214135 Authors: Abigail Lopez Monideepa B. Becerra Benjamin J. Becerra Objective: Addressing mental illness and associated outcomes is a major public health priority in the United States. In this study, our goal was to assess the role of maternal mental illness and its...
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IJERPH, Vol. 16, Pages 4133: Investigation of a Ventilation System for Energy Efficiency and Indoor Environmental Quality in a Renovated Historical Building: A Case Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214133 Authors: Richard Nagy Ľudmila Mečiarová Silvia Vilčeková Eva Krídlová Burdová Danica Košičanová This paper emphasizes the importance of environmental protection regarding the reduction of energy consumption while...
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IJERPH, Vol. 16, Pages 4134: Road Traffic Noise Exposure and Depression/Anxiety: An Updated Systematic Review and Meta-Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214134 Authors: Angel M. Dzhambov Peter Lercher Unlike other World Health Organization evidence reviews, the systematic review on mental disorders could not provide a quantitative estimate of the effect of environmental noise. With that in mind, we aimed to update it with...
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IJERPH, Vol. 16, Pages 4132: Oral Health and Its Associated Factors Among Older Institutionalized Residents—A Systematic Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214132 Authors: Florence M. F. Wong Yannies T. Y. Ng W. Keung Leung The oral health of an ageing population, especially that of the institutionalized elderly population, constitutes a significant concern because it is closely linked to general health and the quality...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5344: Autosomal Dominant Retinitis Pigmentosa Due to Class B Rhodopsin Mutations: An Objective Outcome for Future Treatment Trials International Journal of Molecular Sciences doi: 10.3390/ijms20215344 Authors: Alexander Sumaroka Artur V. Cideciyan Jason Charng Vivian Wu Christian A. Powers Bhavya S. Iyer Brianna Lisi Malgorzata Swider Samuel G. Jacobson Gene therapy for adRP due to RHO mutations was recently shown to prevent photoreceptor...
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IJMS, Vol. 20, Pages 5343: Discrimination of DNA Methylation Signal from Background Variation for Clinical Diagnostics International Journal of Molecular Sciences doi: 10.3390/ijms20215343 Authors: Robersy Sanchez Xiaodong Yang Thomas Maher Sally A. Mackenzie Advances in the study of human DNA methylation variation offer a new avenue for the translation of epigenetic research results to clinical applications. Although current approaches to methylome analysis have been helpful...
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IJMS, Vol. 20, Pages 5342: The Impact of Chemotherapy on the Ovaries: Molecular Aspects and the Prevention of Ovarian Damage International Journal of Molecular Sciences doi: 10.3390/ijms20215342 Authors: Charlotte Sonigo Isabelle Beau Nadine Binart Michaël Grynberg Cancer treatment, such as chemotherapy, induces early ovarian follicular depletion and subsequent infertility. In order to protect gametes from the gonadotoxic effects of chemotherapy, several fertility preservation...
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IJMS, Vol. 20, Pages 5341: Renal Ca2+ and Water Handling in Response to Calcium Sensing Receptor Signaling: Physiopathological Aspects and Role of CaSR-Regulated microRNAs International Journal of Molecular Sciences doi: 10.3390/ijms20215341 Authors: Marianna Ranieri Calcium (Ca2+) is a universal and vital intracellular messenger involved in a diverse range of cellular and biological processes. Changes in the concentration of extracellular Ca2+ can disrupt the normal cellular activities...
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IJMS, Vol. 20, Pages 5340: Serotonin 5-HT4 Receptor Agonists Improve Facilitation of Contextual Fear Extinction in An MPTP-Induced Mouse Model of Parkinson’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms20215340 Authors: Ishii Kinoshita Muroi Previously, we found that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson’s disease (PD) model mice (PD mice) showed facilitation of hippocampal memory extinction via reduced cyclic...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5338: Juvenile Huntington’s Disease Skin Fibroblasts Respond with Elevated Parkin Level and Increased Proteasome Activity as a Potential Mechanism to Counterbalance the Pathological Consequences of Mutant Huntingtin Protein International Journal of Molecular Sciences doi: 10.3390/ijms20215338 Authors: Aladdin Király Boto Regdon Tar Huntington’s disease (HD) is an inherited neurodegenerative disorder, caused by an abnormal polyglutamine...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5334: Development of an Efficient Protocol to Obtain Transgenic Coffee, Coffea arabica L., Expressing the Cry10Aa Toxin of Bacillus thuringiensis International Journal of Molecular Sciences doi: 10.3390/ijms20215334 Authors: Eliana Valencia-Lozano José L. Cabrera-Ponce Miguel A. Gómez-Lim Jorge E. Ibarra This report presents an efficient protocol of the stable genetic transformation of coffee plants expressing the Cry10Aa protein of Bacillus thuringiensis....
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5339: What Does the History of Research on the Repair of DNA Double-Strand Breaks Tell Us?—A Comprehensive Review of Human Radiosensitivity International Journal of Molecular Sciences doi: 10.3390/ijms20215339 Authors: Elise Berthel Mélanie L. Ferlazzo Clément Devic Michel Bourguignon Nicolas Foray Our understanding of the molecular and cellular response to ionizing radiation (IR) has progressed considerably. This is notably the case for the repair and...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5337: Insight into Mechanobiology: How Stem Cells Feel Mechanical Forces and Orchestrate Biological Functions International Journal of Molecular Sciences doi: 10.3390/ijms20215337 Authors: Chiara Argentati Francesco Morena Ilaria Tortorella Martina Bazzucchi Serena Porcellati Carla Emiliani Sabata Martino The cross-talk between stem cells and their microenvironment has been shown to have a direct impact on stem cells’ decisions about proliferation,...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5336: Synthesis and Evaluation of Anticancer Activity of New 4-Acyloxy Derivatives of Robustic Acid International Journal of Molecular Sciences doi: 10.3390/ijms20215336 Authors: Rui Chen Lini Huo Yogini Jaiswal Jianhua Wei Dianpeng Li Jing Zhong Leonard Williams Xing Xia Yan Liang In the present study, a series of 4-acyloxy robustic acid derivatives were synthesized and characterized for evaluation of their anti-cancer activity. The structures...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5335: The Yin-Yang Regulation of Reactive Oxygen Species and MicroRNAs in Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20215335 Authors: Kamesh R. Babu Yvonne Tay Reactive oxygen species (ROS) are highly reactive oxygen-containing chemical species formed as a by-product of normal aerobic respiration and also from a number of other cellular enzymatic reactions. ROS function as key mediators of cellular signaling pathways involved in proliferation,...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5330: Integrative Assessment of Mixture Toxicity of Three Ionic Liquids on Acetylcholinesterase Using a Progressive Approach from 1D Point, 2D Curve, to 3D Surface International Journal of Molecular Sciences doi: 10.3390/ijms20215330 Authors: Huilin Ge Shanshan Tao Min Zhou Bingjun Han Hongqiu Yuan The joint toxicities of [BMIM]BF4, [BMIM]PF6, and [HMIM]BF4 on acetylcholinesterase (AChE) were systematically investigated by using a progressive approach...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5332: Endometrial Immune Dysfunction in Recurrent Pregnancy Loss International Journal of Molecular Sciences doi: 10.3390/ijms20215332 Authors: Carlo Ticconi Adalgisa Pietropolli Nicoletta Di Simone Emilio Piccione Asgerally Fazleabas Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is also a significant reproductive disorder affecting...
Sat Oct 26, 2019 03:00
IJMS, Vol. 20, Pages 5333: Identification of Isoform-Selective Ligands for the Middle Domain of Heat Shock Protein 90 (Hsp90) International Journal of Molecular Sciences doi: 10.3390/ijms20215333 Authors: Oi Wei Mak Raina Chand Jóhannes Reynisson Ivanhoe K. H. Leung The molecular chaperone heat shock protein 90 (Hsp90) is a current inhibition target for the treatment of diseases, including cancer. In humans, there are two major cytosolic isoforms of Hsp90 (Hsp90α and...
Sat Oct 26, 2019 03:00
JCM, Vol. 8, Pages 1802: Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy Journal of Clinical Medicine doi: 10.3390/jcm8111802 Authors: Alicia A. Gingrich Jaime F. Modiano Robert J. Canter Natural killer (NK) cells of the innate immune system are a key focus of research within the field of immuno-oncology based on their ability to recognize and eliminate malignant cells without prior sensitization or priming. However, barriers have...
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