Τρίτη 1 Οκτωβρίου 2019


Cancer Research October 2019; 79 (19)

Breaking Insights

Highlights from Recent Cancer Literature

Review

AuthorChoice Recent Advances Targeting CCR5 for Cancer and Its Role in Immuno-Oncology
Xuanmao Jiao et al.

Cancer Research Highlights

A Breath of Fresh Air: Opening up the Lung Cancer Genome
Anne M. Bowcock

Sequencing the Events That Mediate Progression of Premalignant Lung Lesions
Daniel T. Merrick

Genome and Epigenome

Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas
Fumiharu Ohka et al.

ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer
Steffan Vartanian et al.

AuthorChoice The Open Chromatin Landscape of Non–Small Cell Lung Carcinoma
Zhoufeng Wang et al.

Metabolism and Chemical Biology

Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells
Johanna Erber et al.

Molecular Cell Biology

BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail
Zhong-yi Qin et al.

AuthorChoice Long Noncoding RNA MIR17HG Promotes Colorectal Cancer Progression via miR-17-5p
Jie Xu et al.

The Cdk2–c-Myc–miR-571 Axis Regulates DNA Replication and Genomic Stability by Targeting Geminin
Yi Zhang et al.

MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes
Lucia Casadei et al.

DIS3L2 Promotes Progression of Hepatocellular Carcinoma via hnRNP U-Mediated Alternative Splicing
Songge Xing et al.

Targeting the Chromosomal Passenger Complex Subunit INCENP Induces Polyploidization, Apoptosis, and Senescence in Neuroblastoma
Ming Sun et al.

LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion
Xiu-Hui Zhan et al.

DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor–Positive Breast Cancer Following Endocrine Therapy
Daniel S. Peiffer et al.

AuthorChoice MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1
Huai-Chia Chuang et al.



Tumor Biology and Immunology

AuthorChoice Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E
Ying Zhang et al.

Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
Mercedes Tomé et al.

The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy
Kostyantyn Krysan et al.

AMPK Alpha-1 Intrinsically Regulates the Function and Differentiation of Tumor Myeloid-Derived Suppressor Cells
Jimena Trillo-Tinoco et al.

Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression
Hiromi I. Wettersten et al.

Translational Science

Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma
Choh Yeung et al.

Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma
Charlotte R. Feddersen et al.

Tie2–FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma
Xiaolong Li et al.

Convergence and Technologies

Differential Variation Analysis Enables Detection of Tumor Heterogeneity Using Single-Cell RNA-Sequencing Data
Emily F. Davis-Marcisak et al.

Population and Prevention Science

Posttraumatic Stress Disorder Is Associated with Increased Risk of Ovarian Cancer: A Prospective and Retrospective Longitudinal Cohort Study
Andrea L. Roberts et al.

Letters to the Editor

Quantifying Preexisting Resistant and Persister Populations–Letter
Hitesh B. Mistry et al.

Quantifying Preexisting Resistant and Persister Populations–Response
David M. McClatchy

Correction

Free Article Correction: LOXL2-Mediated Matrix Remodeling in Metastasis and Mammary Gland Involution
Holly E. Barker et al.

Editor's Notes

Free Article Editor's Note: LOX-Mediated Collagen Cross-linking Is Responsible for Fibrosis-Enhanced Metastasis
Thomas R. Cox et al.

Free Article Editor's Note: Suppression of Tumor Cell Growth Both in Nude Mice and in Culture by n-3 Polyunsaturated Fatty Acids: Mediation through Cyclooxygenase-Independent Pathways
Mary D. Boudreau et al.

Free Article Editor's Note: Hemolytic E. coli Promotes Colonic Tumorigenesis in Females
Ye Jin et al.

Free Article Editor's Note: mda-9/Syntenin: A Positive Regulator of Melanoma Metastasis
Habib Boukerche et al.

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