Cancers, Vol. 11, Pages 1497: Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis Cancers doi: 10.3390/cancers11101497 Authors: Kim Cho Yu Jang Yoon Park Cho The established biomarker for hepatocellular carcinoma (HCC), serum α-fetoprotein (AFP), has suboptimal performance in early disease stages. This study aimed to develop a metabolite panel to differentiate early-stage HCC from cirrhosis....
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Cells, Vol. 8, Pages 1208: Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay Cells doi: 10.3390/cells8101208 Authors: Li Ji Porter Broude Roninson Chen Cell-based assays for CDK8/19 inhibition are not easily defined, since there are no known cellular functions unique to these kinases. To solve this problem, we generated derivatives of 293 cells with CRISPR knockout of one or both of CDK8 and CDK19. Double knockout (dKO) of CDK8 and CDK19...
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Children, Vol. 6, Pages 109: Complete and Incomplete Pentalogy of Cantrell Children doi: 10.3390/children6100109 Authors: Kylat Pentalogy of Cantrell (PC) is a malformation characterized by defects in the ventral abdominal wall, lower sternum, diaphragmatic pericardium, anterior diaphragm associated with omphalocele, thoraco-abdominal ectopia cordis, diaphragmatic hernia, and intracardiac abnormalities. PC is stratified as complete or incomplete and we present both the complete and...
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IJERPH, Vol. 16, Pages 3757: Spatial-Temporal Coupling Analysis of the Coordination between Urbanization and Water Ecosystem in the Yangtze River Economic Belt International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16193757 Authors: Han Han Huimin Li Kaize Zhang As a primary pioneering region in China’s ongoing urbanization process, the Yangtze River Economic Belt’s (YREB’s) urbanization process is itself continually accelerating,...
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IJMS, Vol. 20, Pages 4941: Molecular Mechanisms of the Acute Kidney Injury to Chronic Kidney Disease Transition: An Updated View International Journal of Molecular Sciences doi: 10.3390/ijms20194941 Authors: Francesco Guzzi Luigi Cirillo Rosa Maria Roperto Paola Romagnani Elena Lazzeri Increasing evidence has demonstrated the bidirectional link between acute kidney injury (AKI) and chronic kidney disease (CKD) such that, in the clinical setting, the new concept of a unified...
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IJMS, Vol. 20, Pages 4940: The Regulatory Role of MicroRNAs in Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20194940 Authors: Hui-Yi Loh Brendan P. Norman Kok-Song Lai Nik Mohd Afizan Nik Abd. Rahman Noorjahan Banu Mohamed Alitheen Mohd Azuraidi Osman MicroRNAs (miRNAs) are small non-coding RNA molecules which function as critical post-transcriptional gene regulators of various biological functions. Generally, miRNAs negatively regulate gene...
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JCM, Vol. 8, Pages 1636: Papillary Vessel Density Changes After Intravitreal Anti-VEGF Injections in Hypertensive Patients with Central Retinal Vein Occlusion: An Angio-OCT Study Journal of Clinical Medicine doi: 10.3390/jcm8101636 Authors: Nicolai Franceschi Turris Rosati Pirani Mariotti Purpose: To investigate papillary microvascular changes in patients affected by macular edema due to Central Retinal Vein Occlusions (CRVO) after anti-Vascular Endothelial Growth...
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JCM, Vol. 8, Pages 1635: Elevated Hedgehog-Interacting Protein Levels in Subjects with Prediabetes and Type 2 Diabetes Journal of Clinical Medicine doi: 10.3390/jcm8101635 Authors: Lin Hung Chen Cheng Li Lin Chang Wu Ou Background: The prevalence of diabetes is rapidly increasing worldwide and is highly associated with the incidence of cancers. In order to prevent diabetes, early diagnosis of prediabetes is important. However, biomarkers for prediabetes...
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JCM, Vol. 8, Pages 1634: Alternations of Circadian Clock Genes Expression and Oscillation in Obstructive Sleep Apnea Journal of Clinical Medicine doi: 10.3390/jcm8101634 Authors: Yang Lin Lin Lin Chen Friedman Hung Salapatas Lin Lin Circadian misalignment plays an important role in disease processes and can affect disease severity, treatment outcomes, and even survivorship. In this study, we aim to investigate whether expression and daily oscillation...
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Molecules, Vol. 24, Pages 3592: Identification and Migration Studies of Photolytic Decomposition Products of UV-Photoinitiators in Food Packaging Molecules doi: 10.3390/molecules24193592 Authors: Joseph B. Scarsella Nan Zhang Thomas G. Hartman UV-curable inks, coatings, and adhesives are being increasingly used in food packaging systems. When exposed to UV energy, UV-photoinitiators (PI’s) present in the formulations produce free radicals which catalyze polymerization...
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Nanomaterials, Vol. 9, Pages 1421: Near-Field Enhancement and Polarization Selection of a Nano-System for He-Ne Laser Application Nanomaterials doi: 10.3390/nano9101421 Authors: Wang Chu Yu Gao Peng In this paper, we focus on transmission behavior based on the single aperture with a scatter. Both the near-field enhancement and polarization selection can be achieved numerically with a proposed nano-system under He-Ne laser wavelength. The nano-system consists of an Ag...
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Publications, Vol. 7, Pages 61: Perceived Challenges to Anglophone Publication at Three Universities in Chile Publications doi: 10.3390/publications7040061 Authors: Broekhoff It is well documented that non-Anglophone scholars face enormous pressures to publish in peer-reviewed English-medium journals both for their own advancement and for institutional prestige. Yet many of them receive little support and face big challenges. Scholars’ perceptions of these challenges often...
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