Journal of Clinical Medicine
- JCM, Vol. 8, Pages 1581: Photodynamic Therapy: A Brief HistoryJCM, Vol. 8, Pages 1581: Photodynamic Therapy: A Brief History Journal of Clinical Medicine doi: 10.3390/jcm8101581 Authors: David Kessel Photodynamic therapy (PDT) involves the selective sensitization of tissues to light. A major advance in the field occurred when Thomas Dougherty at the Roswell Park Cancer Institute initiated a series of clinical studies that eventually led to FDA approval of the procedure. This report contains a s
- JCM, Vol. 8, Pages 1580: Higher Acid-Base Imbalance Associated with Respiratory Failure Could Decrease the Survival of Patients with Scrub Typhus during Intensive Care Unit Stay: A Gene Set Enrichment AnalysisJCM, Vol. 8, Pages 1580: Higher Acid-Base Imbalance Associated with Respiratory Failure Could Decrease the Survival of Patients with Scrub Typhus during Intensive Care Unit Stay: A Gene Set Enrichment Analysis Journal of Clinical Medicine doi: 10.3390/jcm8101580 Authors: Kyoung Min Moon Kyueng-Whan Min Mi-Hye Kim Dong-Hoon Kim Byoung Kwan Son Youngha Oh Woonyong Jung Mijung Kwon O-Yu Kwon Ninety percent of pat
- JCM, Vol. 8, Pages 1579: TREM-1 Is Upregulated in Experimental Periodontitis, and Its Blockade Inhibits IL-17A and RANKL Expression and Suppresses Bone lossJCM, Vol. 8, Pages 1579: TREM-1 Is Upregulated in Experimental Periodontitis, and Its Blockade Inhibits IL-17A and RANKL Expression and Suppresses Bone loss Journal of Clinical Medicine doi: 10.3390/jcm8101579 Authors: Nagihan Bostanci Toshiharu Abe Georgios N. Belibasakis George Hajishengallis Aim: Triggering receptor expressed on myeloid cells-1 (TREM-1) is a modifier of local and systemic inflammation. There is clinical e
- JCM, Vol. 8, Pages 1573: Associations between Race, Discrimination, Community Violence, Traumatic Life Events, and Psychosis-Like Experiences in a Sample of College StudentsJCM, Vol. 8, Pages 1573: Associations between Race, Discrimination, Community Violence, Traumatic Life Events, and Psychosis-Like Experiences in a Sample of College Students Journal of Clinical Medicine doi: 10.3390/jcm8101573 Authors: Rouhakhtar Pitts Schiffman Self-report tools of psychosis-like experiences contribute to the understanding of psychosis and may aid in identification and prevention efforts across the severity
- JCM, Vol. 8, Pages 1578: Insights into Amyotrophic Lateral Sclerosis from a Machine Learning PerspectiveJCM, Vol. 8, Pages 1578: Insights into Amyotrophic Lateral Sclerosis from a Machine Learning Perspective Journal of Clinical Medicine doi: 10.3390/jcm8101578 Authors: Jonathan Gordon Boaz Lerner Objective: Amyotrophic lateral sclerosis (ALS) disease state prediction usually assumes linear progression and uses a classifier evaluated by its accuracy. Since disease progression is not linear, and the accuracy measurement cannot tell l
- JCM, Vol. 8, Pages 1577: BRAF Mutations and Dysregulation of the MAP Kinase Pathway Associated to Sinonasal Mucosal MelanomasJCM, Vol. 8, Pages 1577: BRAF Mutations and Dysregulation of the MAP Kinase Pathway Associated to Sinonasal Mucosal Melanomas Journal of Clinical Medicine doi: 10.3390/jcm8101577 Authors: Maria Colombino Panagiotis Paliogiannis Antonio Cossu Valli De Re Gianmaria Miolo Gerardo Botti Giosuè Scognamiglio Paolo Antonio Ascierto Davide Adriano Santeufemia Filippo Fraggetta Antonella Manca Maria Cristina Sini
- JCM, Vol. 8, Pages 1575: Pain Perception and Acceptance of Illness in Patients Undergoing Phacoemulsification Cataract Surgery under Drip AnesthesiaJCM, Vol. 8, Pages 1575: Pain Perception and Acceptance of Illness in Patients Undergoing Phacoemulsification Cataract Surgery under Drip Anesthesia Journal of Clinical Medicine doi: 10.3390/jcm8101575 Authors: Kowalczuk Cybulski Cybulski Krajewska-Kułak For many years, cataracts have been the main cause of vision loss and vision impairments in the world (43% and 33%, respectively). Currently, the most common surgical me
- JCM, Vol. 8, Pages 1574: Preclinical Study in Vivo for New Pharmacological Approaches in Inflammatory Bowel Disease: A Systematic Review of Chronic Model of TNBS-Induced ColitisJCM, Vol. 8, Pages 1574: Preclinical Study in Vivo for New Pharmacological Approaches in Inflammatory Bowel Disease: A Systematic Review of Chronic Model of TNBS-Induced Colitis Journal of Clinical Medicine doi: 10.3390/jcm8101574 Authors: Silva Pinto Mateus The preclinical studies in vivo provide means of characterizing physiologic interactions when our understanding of such processes is insufficient to allow replacement wi
- JCM, Vol. 8, Pages 1572: Long-Term Outcome and Rejection After Allogeneic Uterus Transplantation in Cynomolgus MacaquesJCM, Vol. 8, Pages 1572: Long-Term Outcome and Rejection After Allogeneic Uterus Transplantation in Cynomolgus Macaques Journal of Clinical Medicine doi: 10.3390/jcm8101572 Authors: Kisu Ishigaki Emoto Kato Yamada Matsubara Obara Masugi Matoba Adachi Banno Saiki Itagaki Kawamoto Iwatani Nakagawa Tsuchiya Sasamura Urano Ema Ogasawara Aoki Nakagawa S
- JCM, Vol. 8, Pages 1576: Growth Differentiation Factor-15 (GDF-15) is a Biomarker of Muscle Wasting and Renal Dysfunction in Preoperative Cardiovascular Surgery PatientsJCM, Vol. 8, Pages 1576: Growth Differentiation Factor-15 (GDF-15) is a Biomarker of Muscle Wasting and Renal Dysfunction in Preoperative Cardiovascular Surgery Patients Journal of Clinical Medicine doi: 10.3390/jcm8101576 Authors: Nakajima Shibasaki Sawaguchi Haruyama Kaneda Nakajima Hasegawa Arikawa Obi Sakuma Ogawa Toyoda Nakamura Abe Fukuda Inoue Frailty and sarcopenia
- JCM, Vol. 8, Pages 1571: Low Levels of Low-Density Lipoprotein Cholesterol and Mortality Outcomes in Non-Statin UsersJCM, Vol. 8, Pages 1571: Low Levels of Low-Density Lipoprotein Cholesterol and Mortality Outcomes in Non-Statin Users Journal of Clinical Medicine doi: 10.3390/jcm8101571 Authors: Sung Huh Ryu Lee Scorletti Byrne Kim Hyun Ko We aimed to test the association between low-density lipoprotein cholesterol (LDL-C) and cardiovascular disease (CVD), cancer, and all-cause mortality in non-statin users. A total
- JCM, Vol. 8, Pages 1570: Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling PatternsJCM, Vol. 8, Pages 1570: Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns Journal of Clinical Medicine doi: 10.3390/jcm8101570 Authors: Hira Hasan Sin-Hee Park Cyril Auger Eugenia Belcastro Kensuke Matsushita Benjamin Marchandot Hyun-Ho Lee Abdul Wahid Qureshi Gilles Kauffenstein Patrick Ohlmann Valérie B Schini-Kerth Laurence Jesel Olivie
- JCM, Vol. 8, Pages 1569: Iron Deficiency in Acute Decompensated Heart FailureJCM, Vol. 8, Pages 1569: Iron Deficiency in Acute Decompensated Heart Failure Journal of Clinical Medicine doi: 10.3390/jcm8101569 Authors: Anna Beale Davis Carballo Jerome Stirnemann Nicolas Garin Thomas Agoritsas Jacques Serratrice David Kaye Philippe Meyer Sebastian Carballo The aim of this study was to characterize iron deficiency (ID) in acutely decompensated heart failure (ADHF) and identify whether ID i
- JCM, Vol. 8, Pages 1568: Increased Citrullinated Histone H3 Levels in the Early Post-Resuscitative Period Are Associated with Poor Neurologic Function in Cardiac Arrest Survivors—A Prospective Observational StudyJCM, Vol. 8, Pages 1568: Increased Citrullinated Histone H3 Levels in the Early Post-Resuscitative Period Are Associated with Poor Neurologic Function in Cardiac Arrest Survivors—A Prospective Observational Study Journal of Clinical Medicine doi: 10.3390/jcm8101568 Authors: Lisa-Marie Mauracher Nina Buchtele Christian Schörgenhofer Christoph Weiser Harald Herkner Anne Merrelaar Alexander O. Spiel Lena Hell Cihan Ay
- JCM, Vol. 8, Pages 1567: Investigating Risk Factors for Complications after Ileostomy Reversal in Low Anterior Rectal Resection Patients: An Observational StudyJCM, Vol. 8, Pages 1567: Investigating Risk Factors for Complications after Ileostomy Reversal in Low Anterior Rectal Resection Patients: An Observational Study Journal of Clinical Medicine doi: 10.3390/jcm8101567 Authors: Mateusz Rubinkiewicz Jan Witowski Michał Wysocki Magdalena Pisarska Stanisław Kłęk Andrzej Budzyński Michał Pędziwiatr Introduction: Defunctioning ileostomy has been widely used in patients underg
- JCM, Vol. 8, Pages 1566: Correlation between B7-H4 and Survival of Non-Small-Cell Lung Cancer Patients Treated with NivolumabJCM, Vol. 8, Pages 1566: Correlation between B7-H4 and Survival of Non-Small-Cell Lung Cancer Patients Treated with Nivolumab Journal of Clinical Medicine doi: 10.3390/jcm8101566 Authors: Carlo Genova Simona Boccardo Marco Mora Erika Rijavec Federica Biello Giovanni Rossi Marco Tagliamento Maria Dal Bello Simona Coco Angela Alama Irene Vanni Giulia Barletta Rita Bianchi Claudia Maggioni Paolo Bruzz
- JCM, Vol. 8, Pages 1565: Allogeneic Hematopoietic Stem Cell Transplantation for Adults with Sickle Cell DiseaseJCM, Vol. 8, Pages 1565: Allogeneic Hematopoietic Stem Cell Transplantation for Adults with Sickle Cell Disease Journal of Clinical Medicine doi: 10.3390/jcm8101565 Authors: Santosh L. Saraf Damiano Rondelli Sickle cell disease (SCD) is an inherited red blood cell disorder that leads to substantial morbidity and early mortality. Acute and chronic SCD-related complications increase with older age, and therapies are urgently needed
- JCM, Vol. 8, Pages 1564: Osteoporosis from an Endocrine Perspective: The Role of Hormonal Changes in the ElderlyJCM, Vol. 8, Pages 1564: Osteoporosis from an Endocrine Perspective: The Role of Hormonal Changes in the Elderly Journal of Clinical Medicine doi: 10.3390/jcm8101564 Authors: Rossella Cannarella Federica Barbagallo Rosita A. Condorelli Antonio Aversa Sandro La Vignera Aldo E. Calogero Introduction: Osteoporosis is increasingly prevalent in the elderly, with fractures mostly occurring in women and men who are older than
- JCM, Vol. 8, Pages 1563: A Population Pharmacokinetic Model of Intravenous Dexmedetomidine for Mechanically Ventilated Children after NeurosurgeryJCM, Vol. 8, Pages 1563: A Population Pharmacokinetic Model of Intravenous Dexmedetomidine for Mechanically Ventilated Children after Neurosurgery Journal of Clinical Medicine doi: 10.3390/jcm8101563 Authors: In-Kyung Song SoJeong Yi Hyeong-Seok Lim Ji-Hyun Lee Eun-Hee Kim Joo-Youn Cho Min-Chang Kim Jin-Tae Kim Hee-Soo Kim Dexmedetomidine is a selective alpha-2 adrenergic agonist with concurrent sedative and a
- JFB, Vol. 10, Pages 45: Cell-Penetrating Peptides as a Tool for the Cellular Uptake of a Genetically Modified Nitroreductase for use in Directed Enzyme Prodrug TherapyJFB, Vol. 10, Pages 45: Cell-Penetrating Peptides as a Tool for the Cellular Uptake of a Genetically Modified Nitroreductase for use in Directed Enzyme Prodrug Therapy Journal of Functional Biomaterials doi: 10.3390/jfb10040045 Authors: Anderson Hobbs Gwenin Ball Bennie Coulter Gwenin Directed enzyme prodrug therapy (DEPT) involves the delivery of a prodrug-activating enzyme to a solid tumour site, followed b
- JoF, Vol. 5, Pages 92: Repositionable Compounds with Antifungal Activity against Multidrug Resistant Candida auris Identified in the Medicines for Malaria Venture’s Pathogen BoxJoF, Vol. 5, Pages 92: Repositionable Compounds with Antifungal Activity against Multidrug Resistant Candida auris Identified in the Medicines for Malaria Venture’s Pathogen Box Journal of Fungi doi: 10.3390/jof5040092 Authors: Wall Herrera Lopez-Ribot Background. Candida auris has spread rapidly around the world as a causative agent of invasive candidiasis in health care facilities and there is an urgent need to find new op
- J. Imaging, Vol. 5, Pages 80: Tip Crack Imaging on Transparent Materials by Digital Holographic MicroscopyJ. Imaging, Vol. 5, Pages 80: Tip Crack Imaging on Transparent Materials by Digital Holographic Microscopy Journal of Imaging doi: 10.3390/jimaging5100080 Authors: Zhou Li Shen He Zhang Yu Tornari With this study, we propose a method to image the tip crack on transparent materials by using digital holographic microscopy. More specifically, an optical system based on Mach–Zehnder interference along with
- J. Imaging, Vol. 5, Pages 79: A Contrast-Guided Approach for the Enhancement of Low-Lighting Underwater ImagesJ. Imaging, Vol. 5, Pages 79: A Contrast-Guided Approach for the Enhancement of Low-Lighting Underwater Images Journal of Imaging doi: 10.3390/jimaging5100079 Authors: Tunai Porto Marques Alexandra Branzan Albu Maia Hoeberechts Underwater images are often acquired in sub-optimal lighting conditions, in particular at profound depths where the absence of natural light demands the use of artificial lighting. Low-lighting images im
- Medicina, Vol. 55, Pages 667: Upregulated Expression of Macrophage Migration Inhibitory Factor, Its Analogue D-Dopachrome Tautomerase, and the CD44 Receptor in Peripheral CD4 T Cells from Clinically Isolated Syndrome Patients with Rapid Conversion to Clinical Defined Multiple SclerosisMedicina, Vol. 55, Pages 667: Upregulated Expression of Macrophage Migration Inhibitory Factor, Its Analogue D-Dopachrome Tautomerase, and the CD44 Receptor in Peripheral CD4 T Cells from Clinically Isolated Syndrome Patients with Rapid Conversion to Clinical Defined Multiple Sclerosis Medicina doi: 10.3390/medicina55100667 Authors: Cavalli Mazzon Basile Mangano Di Marco Bramanti Nicoletti Fagone Petralia
- Medicina, Vol. 55, Pages 668: Cognition, Mood and Sleep in Menopausal Transition: The Role of Menopause Hormone TherapyMedicina, Vol. 55, Pages 668: Cognition, Mood and Sleep in Menopausal Transition: The Role of Menopause Hormone Therapy Medicina doi: 10.3390/medicina55100668 Authors: Gava Orsili Alvisi Mancini Seracchioli Meriggiola During the menopausal transition, which begins four to six years before cessation of menses, middle-aged women experience a progressive change in ovarian activity and a physiologic deterioration of
- Medicina, Vol. 55, Pages 665: Prevalence of Low Energy Availability in Competitively Trained Male Endurance AthletesMedicina, Vol. 55, Pages 665: Prevalence of Low Energy Availability in Competitively Trained Male Endurance Athletes Medicina doi: 10.3390/medicina55100665 Authors: Lane Hackney Smith-Ryan Kucera Registar-Mihalik Ondrak Background and Objectives: Relative energy deficiency in sport (RED-S) has been introduced as a broad-spectrum syndrome leading to possible dysfunction in numerous physiological systems, driven pr
- Medicina, Vol. 55, Pages 664: Microwave Thermal Ablation versus Open Partial Nephrectomy for the Treatment of Small Renal Tumors in Patients Over 70 Years OldMedicina, Vol. 55, Pages 664: Microwave Thermal Ablation versus Open Partial Nephrectomy for the Treatment of Small Renal Tumors in Patients Over 70 Years Old Medicina doi: 10.3390/medicina55100664 Authors: Anglickis Anglickienė Andreikaitė Skrebūnas Background and objectives: Microwave thermal ablation (MWT) is one of the treatment options for kidney cancer. However, for patients over 70 years old the safety and oncolog
- Medicina, Vol. 55, Pages 666: Factors Influencing Quality of Life during the First Trimester of Pregnancy: A Prospective Cohort StudyMedicina, Vol. 55, Pages 666: Factors Influencing Quality of Life during the First Trimester of Pregnancy: A Prospective Cohort Study Medicina doi: 10.3390/medicina55100666 Authors: Jakubauskiene Jakubauskas Mainelis Buzinskiene Drasutiene Ramasauskaite Poskus Introduction: Pregnancy, delivery and postpartum periods are associated with fast changesleading to decreased self-confidence, anxiety, stress or even
- Metabolites, Vol. 9, Pages 212: Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPDMetabolites, Vol. 9, Pages 212: Dysregulation of the Tryptophan Pathway Evidences Gender Differences in COPD Metabolites doi: 10.3390/metabo9100212 Authors: Naz Bhat Ståhl Forsslund Sköld Wheelock Wheelock Increased activity of indoleamine 2,3-dioxygenase (IDO) and tryptophan hydroxylase (TPH) have been reported in individuals with chronic obstructive pulmonary disease (COPD). We therefore investigated the e
- MPs, Vol. 2, Pages 79: Isolation, Maintenance and Differentiation of Primary Tracheal Basal Cells from Adult Rhesus MacaqueMPs, Vol. 2, Pages 79: Isolation, Maintenance and Differentiation of Primary Tracheal Basal Cells from Adult Rhesus Macaque Methods and Protocols doi: 10.3390/mps2040079 Authors: Engler Mostoslavsky Miller Rock In this report, we describe methodologies for the isolation and culture of primary rhesus macaque tracheal basal cells, their cryopreservation, long term storage and differentiation. These are comparable to state-
- Microorganisms, Vol. 7, Pages 414: Oncogenic Virome Benefits from the Different Vaginal Microbiome-Immune AxesMicroorganisms, Vol. 7, Pages 414: Oncogenic Virome Benefits from the Different Vaginal Microbiome-Immune Axes Microorganisms doi: 10.3390/microorganisms7100414 Authors: Giuseppina Campisciano Tarik Gheit Francesco De Seta Carolina Cason Nunzia Zanotta Serena Delbue Giuseppe Ricci Pasquale Ferrante Massimo Tommasino Manola Comar The picture of dynamic interaction between oncogenic viruses and the vaginal ba
- Microorganisms, Vol. 7, Pages 413: Detection of Increased Relative Expression Units of Bacteroides and Prevotella, and Decreased Clostridium leptum in Stool Samples from Brazilian Rheumatoid Arthritis Patients: A Pilot StudyMicroorganisms, Vol. 7, Pages 413: Detection of Increased Relative Expression Units of Bacteroides and Prevotella, and Decreased Clostridium leptum in Stool Samples from Brazilian Rheumatoid Arthritis Patients: A Pilot Study Microorganisms doi: 10.3390/microorganisms7100413 Authors: Rodrigues Cayres Gonçalves Takaoka Lengert Tansini Brisotti Sasdelli Oliveira Interactions between gut microbes and dis
- Microorganisms, Vol. 7, Pages 412: Insights into Biodegradation Related Metabolism in an Abnormally Low Dissolved Inorganic Carbon (DIC) Petroleum-Contaminated Aquifer by Metagenomics AnalysisMicroorganisms, Vol. 7, Pages 412: Insights into Biodegradation Related Metabolism in an Abnormally Low Dissolved Inorganic Carbon (DIC) Petroleum-Contaminated Aquifer by Metagenomics Analysis Microorganisms doi: 10.3390/microorganisms7100412 Authors: Pingping Cai Zhuo Ning Ningning Zhang Min Zhang Caijuan Guo Manlan Niu Jiansheng Shi In petroleum-contaminated aquifers, biodegradation is always associated with vario
- Microorganisms, Vol. 7, Pages 411: Targeted High-Throughput Sequencing Identifies Predominantly Fungal Pathogens in Patients with Clinically Infectious, Culture-Negative Endophthalmitis in South IndiaMicroorganisms, Vol. 7, Pages 411: Targeted High-Throughput Sequencing Identifies Predominantly Fungal Pathogens in Patients with Clinically Infectious, Culture-Negative Endophthalmitis in South India Microorganisms doi: 10.3390/microorganisms7100411 Authors: Jaishree Gandhi Rajagopalaboopathi Jayasudha Poonam Naik Savitri Sharma Vivek Pravin Dave Joveeta Joseph To evaluate the clinical utility of high-throughput seque
- Molecules, Vol. 24, Pages 3564: Quantitative Analysis of Organic Liquid Three-Component Systems: Near-Infrared Transmission versus Raman Spectroscopy, Partial Least Squares versus Classical Least Squares Regression Evaluation and Volume versus Weight Percent Concentration UnitsMolecules, Vol. 24, Pages 3564: Quantitative Analysis of Organic Liquid Three-Component Systems: Near-Infrared Transmission versus Raman Spectroscopy, Partial Least Squares versus Classical Least Squares Regression Evaluation and Volume versus Weight Percent Concentration Units Molecules doi: 10.3390/molecules24193564 Authors: Yan Ma Xiong Siesler Qi Zhang The band shapes and band positions of near-infrared (NIR)
- Molecules, Vol. 24, Pages 3562: Structural Basis for the Regulation of PPARγ Activity by ImatinibMolecules, Vol. 24, Pages 3562: Structural Basis for the Regulation of PPARγ Activity by Imatinib Molecules doi: 10.3390/molecules24193562 Authors: Jang Kim Han Imatinib is an effective anticancer drug for the treatment of leukemia. Interestingly, when an FDA-approved drug library was tested for agents that block peroxisome proliferator-activated receptor γ (PPARγ) phosphorylation at Ser245 to evaluate possibilit
- Molecules, Vol. 24, Pages 3563: Water in Mesoporous Confinement: Glass-To-Liquid Transition or Freezing of Molecular Reorientation Dynamics?Molecules, Vol. 24, Pages 3563: Water in Mesoporous Confinement: Glass-To-Liquid Transition or Freezing of Molecular Reorientation Dynamics? Molecules doi: 10.3390/molecules24193563 Authors: Schranz Soprunyuk The first mechanical relaxation measurements (f = 400 Hz) of water confined in micro-porous silica were performed more than 40 years ago. The authors reported a so called “capillary transition” (here denoted as
- Molecules, Vol. 24, Pages 3560: Antitumor Efficacy of Liposome-Encapsulated NVP-BEZ235 Combined with Irreversible Electroporation for Head and Neck CancerMolecules, Vol. 24, Pages 3560: Antitumor Efficacy of Liposome-Encapsulated NVP-BEZ235 Combined with Irreversible Electroporation for Head and Neck Cancer Molecules doi: 10.3390/molecules24193560 Authors: Li Tian Lucas Wang Yang Qiao Linfeng Lu Patrick Lee Ashley Chang Saisree Ravi Thomas A. Rogers Marites P. Melancon Irreversible electroporation (IRE) kills tumor cells by the delivery of short pulses of stron
- Molecules, Vol. 24, Pages 3561: Heat-Dependent Desorption of Proanthocyanidins from Grape-Derived Cell Wall Material under Variable Ethanol Concentrations in Model Wine SystemsMolecules, Vol. 24, Pages 3561: Heat-Dependent Desorption of Proanthocyanidins from Grape-Derived Cell Wall Material under Variable Ethanol Concentrations in Model Wine Systems Molecules doi: 10.3390/molecules24193561 Authors: Jordan W. Beaver Konrad V. Miller Cristina Medina-Plaza Nicolas Dokoozlian Ravi Ponangi Thomas Blair David Block Anita Oberholster Desorption of proanthocyanidins (PA) from grape cell wall
- Molecules, Vol. 24, Pages 3559: Chain Substituted Cannabilactones with Selectivity for the CB2 Cannabinoid ReceptorMolecules, Vol. 24, Pages 3559: Chain Substituted Cannabilactones with Selectivity for the CB2 Cannabinoid Receptor Molecules doi: 10.3390/molecules24193559 Authors: Shakiru O. Alapafuja Spyros P. Nikas Thanh C. Ho Fei Tong Othman Benchama Alexandros Makriyannis In earlier work, we reported a novel class of CB2 selective ligands namely cannabilactones. These compounds carry a dimethylheptyl substituent at C3, which is
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