Journal of Clinical Medicine
- JCM, Vol. 8, Pages 1710: Post-Lumbar Puncture Headache—Does Hydration before Puncture Prevent Headache and Affect Cerebral Blood Flow?JCM, Vol. 8, Pages 1710: Post-Lumbar Puncture Headache—Does Hydration before Puncture Prevent Headache and Affect Cerebral Blood Flow? Journal of Clinical Medicine doi: 10.3390/jcm8101710 Authors: Magdalena Nowaczewska Beata Kukulska-Pawluczuk Henryk Kaźmierczak Katarzyna Pawlak-Osińska Headache is a common complication after diagnostic lumbar puncture (DLP). We aimed to check whether hydration before puncture influences the
- JCM, Vol. 8, Pages 1709: Data Science for Extubation Prediction and Value of Information in Surgical Intensive Care UnitJCM, Vol. 8, Pages 1709: Data Science for Extubation Prediction and Value of Information in Surgical Intensive Care Unit Journal of Clinical Medicine doi: 10.3390/jcm8101709 Authors: Tsung-Lun Tsai Min-Hsin Huang Chia-Yen Lee Wu-Wei Lai Besides the traditional indices such as biochemistry, arterial blood gas, rapid shallow breathing index (RSBI), acute physiology and chronic health evaluation (APACHE) II score, this study su
- JCM, Vol. 8, Pages 1708: The Impact of Older Age on Functional Recovery and Quality of Life Outcomes after Surgical Decompression for Degenerative Cervical Myelopathy: Results from an Ambispective, Propensity-Matched Analysis from the CSM-NA and CSM-I International, Multi-Center StudiesJCM, Vol. 8, Pages 1708: The Impact of Older Age on Functional Recovery and Quality of Life Outcomes after Surgical Decompression for Degenerative Cervical Myelopathy: Results from an Ambispective, Propensity-Matched Analysis from the CSM-NA and CSM-I International, Multi-Center Studies Journal of Clinical Medicine doi: 10.3390/jcm8101708 Authors: Jamie R. F. Wilson Jetan H. Badhiwala Fan Jiang Jefferson R. Wilson Branko Kopjar
- JCM, Vol. 8, Pages 1706: Comment from the Editor to the Special Issue: “Periodontitis: From Dysbiotic Microbial Immune Response to Systemic Inflammation”JCM, Vol. 8, Pages 1706: Comment from the Editor to the Special Issue: “Periodontitis: From Dysbiotic Microbial Immune Response to Systemic Inflammation” Journal of Clinical Medicine doi: 10.3390/jcm8101706 Authors: Oscarsson Johansson The human oral cavity contains a large number of different microbial habitats. When microbes from the oral indigenous flora colonize the interspace between the tooth and the connective tissue, the
- JCM, Vol. 8, Pages 1707: Exercise and Cognitive FunctionJCM, Vol. 8, Pages 1707: Exercise and Cognitive Function Journal of Clinical Medicine doi: 10.3390/jcm8101707 Authors: Loprinzi Lovorn Cognitive function is associated with longevity and is of critical importance for optimal daily functioning[...]
- JCM, Vol. 8, Pages 1704: Heart Rate Variability and Perceived Stress as Measurements of Relaxation ResponseJCM, Vol. 8, Pages 1704: Heart Rate Variability and Perceived Stress as Measurements of Relaxation Response Journal of Clinical Medicine doi: 10.3390/jcm8101704 Authors: Mutsuhiro Nakao Stress is a term used to define the body’s physiological and psychological reactions to circumstances that require behavioral adjustment [...]
- JCM, Vol. 8, Pages 1700: The Association between Nutritional Markers and Heart Rate Variability Indices in Patients Undergoing Chronic HemodialysisJCM, Vol. 8, Pages 1700: The Association between Nutritional Markers and Heart Rate Variability Indices in Patients Undergoing Chronic Hemodialysis Journal of Clinical Medicine doi: 10.3390/jcm8101700 Authors: Eric Wu Ya-Ting Huang Yu-Ming Chang I-Ling Chen Chuan-Lan Yang Show-Chin Leu Hung-Li Su Jsun-Liang Kao Shih-Ching Tsai Rong-Na Jhen Chih-Chung Shiao The associations between nutritional marker
- JCM, Vol. 8, Pages 1702: NK Cell-Based Immunotherapy for Hematological MalignanciesJCM, Vol. 8, Pages 1702: NK Cell-Based Immunotherapy for Hematological Malignancies Journal of Clinical Medicine doi: 10.3390/jcm8101702 Authors: Simona Sivori Raffaella Meazza Concetta Quintarelli Simona Carlomagno Mariella Della Chiesa Michela Falco Lorenzo Moretta Franco Locatelli Daniela Pende Natural killer (NK) lymphocytes are an integral component of the innate immune system and represent important effe
- JCM, Vol. 8, Pages 1703: Outcomes of Total Hip Arthroplasty in Patients with Osteonecrosis of the Femoral Head Following Surgical Treatment of Brain TumorsJCM, Vol. 8, Pages 1703: Outcomes of Total Hip Arthroplasty in Patients with Osteonecrosis of the Femoral Head Following Surgical Treatment of Brain Tumors Journal of Clinical Medicine doi: 10.3390/jcm8101703 Authors: Seung-Jae Lim Chan-Woo Park Dong-Uk Kim Kwangjoon Han Minkyu Seo Young-Wan Moon Jung-Il Lee Youn-Soo Park Corticosteroids have been widely used in patients with brain tumors to reduce tumor-associat
- JCM, Vol. 8, Pages 1699: Association of Nicotine with Osteochondrogenesis and Osteoarthritis Development: The State of the Art of Preclinical ResearchJCM, Vol. 8, Pages 1699: Association of Nicotine with Osteochondrogenesis and Osteoarthritis Development: The State of the Art of Preclinical Research Journal of Clinical Medicine doi: 10.3390/jcm8101699 Authors: Xiaoyu Cai Liang Gao Magali Cucchiarini Henning Madry The deleterious effects of nicotine on various health conditions have been well documented. Although many orthopedic diseases are adversely affected by nicotine,
- JCM, Vol. 8, Pages 1701: Optimizing Hydroxyurea Treatment for Sickle Cell Disease Patients: The Pharmacokinetic ApproachJCM, Vol. 8, Pages 1701: Optimizing Hydroxyurea Treatment for Sickle Cell Disease Patients: The Pharmacokinetic Approach Journal of Clinical Medicine doi: 10.3390/jcm8101701 Authors: Charlotte Nazon Amelia-Naomi Sabo Guillaume Becker Jean-Marc Lessinger Véronique Kemmel Catherine Paillard Background: Hydroxyurea (HU) is a FDA- and EMA-approved drug that earned an important place in the treatment of patients with severe
- JCM, Vol. 8, Pages 1705: Effects of Pet Insects on Cognitive Function among the Elderly: An fMRI StudyJCM, Vol. 8, Pages 1705: Effects of Pet Insects on Cognitive Function among the Elderly: An fMRI Study Journal of Clinical Medicine doi: 10.3390/jcm8101705 Authors: Ji-Yeon Park Hae-Jin Ko A-Sol Kim Ha-Na Moon Hye-In Choi Jin-Hee Kim Yongmin Chang Seong-Hyun Kim Animal-assisted therapy has positive effects on cognitive function, depression, performance ability, and social functioning in elderly patients. The aim
- JCM, Vol. 8, Pages 1696: Validation of Identified Susceptible Gene Variants for New-Onset Diabetes in Renal Transplant RecipientsJCM, Vol. 8, Pages 1696: Validation of Identified Susceptible Gene Variants for New-Onset Diabetes in Renal Transplant Recipients Journal of Clinical Medicine doi: 10.3390/jcm8101696 Authors: Hyeon Hwang Kyung-Won Hong Jin Kim Yang Kim Ju Moon Kyung Jeong Sang Lee The Korean Organ Transplantation Registry Study Group Genome-wide association studies (GWAS) and candidate gene approaches have identified single nucl
- JCM, Vol. 8, Pages 1697: The Association of Glucocorticosteroid Treatment with WBC Count in Patients with COPD ExacerbationJCM, Vol. 8, Pages 1697: The Association of Glucocorticosteroid Treatment with WBC Count in Patients with COPD Exacerbation Journal of Clinical Medicine doi: 10.3390/jcm8101697 Authors: Amit Frenkel Eric Kachko Victor Novack Moti Klein Evgeni Brotfain Leonid Koyfman Nimrod Maimon Systematic glucocorticosteroids (GCS) are used to treat chronic obstructive pulmonary disease (COPD) and can cause leukocytosis. Distingui
- JCM, Vol. 8, Pages 1698: Exploring the Ability of Electronic Nose Technology to Recognize Interstitial Lung Diseases (ILD) by Non-Invasive Breath Screening of Exhaled Volatile Compounds (VOC): A Pilot Study from the European IPF Registry (eurIPFreg) and BiobankJCM, Vol. 8, Pages 1698: Exploring the Ability of Electronic Nose Technology to Recognize Interstitial Lung Diseases (ILD) by Non-Invasive Breath Screening of Exhaled Volatile Compounds (VOC): A Pilot Study from the European IPF Registry (eurIPFreg) and Biobank Journal of Clinical Medicine doi: 10.3390/jcm8101698 Authors: Ekaterina Krauss Jana Haberer Olga Maurer Guillermo Barreto Fotios Drakopanagiotakis Maria Degen Wern
- JCM, Vol. 8, Pages 1695: Clinical Benefit of Long-Term Disease Control with Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma PatientsJCM, Vol. 8, Pages 1695: Clinical Benefit of Long-Term Disease Control with Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma Patients Journal of Clinical Medicine doi: 10.3390/jcm8101695 Authors: Marina Silvia Parisi Salvatore Leotta Alessandra Romano Vittorio Del Fabro Enrica Antonia Martino Valeria Calafiore Rachele Giubbolini Uros Markovic Valerio Leotta Mary Ann Di Giorgio Daniele Tib
- JCM, Vol. 8, Pages 1694: ICSI Versus Conventional IVF in Women Aged 40 Years or More and Unexplained Infertility: A Retrospective Evaluation of 685 Cycles with Propensity Score ModelJCM, Vol. 8, Pages 1694: ICSI Versus Conventional IVF in Women Aged 40 Years or More and Unexplained Infertility: A Retrospective Evaluation of 685 Cycles with Propensity Score Model Journal of Clinical Medicine doi: 10.3390/jcm8101694 Authors: Gianluca Gennarelli Andrea Carosso Stefano Canosa Claudia Filippini Sara Cesarano Carlotta Scarafia Nicole Brunod Alberto Revelli Chiara Benedetto This study compared t
- Medicina, Vol. 55, Pages 696: Clinical Significance of Isolates Known to Be Blood Culture Contaminants in Pediatric PatientsMedicina, Vol. 55, Pages 696: Clinical Significance of Isolates Known to Be Blood Culture Contaminants in Pediatric Patients Medicina doi: 10.3390/medicina55100696 Authors: Sejong Chun Cheol-In Kang Yae-Jean Kim Nam Yong Lee Background and objectives: The objective of this study was to investigate the clinical significance of isolates from blood stream infection known to be blood culture contaminants in pediatric patients. M
- Medicina, Vol. 55, Pages 697: Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease—A Cross Sectional StudyMedicina, Vol. 55, Pages 697: Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease—A Cross Sectional Study Medicina doi: 10.3390/medicina55100697 Authors: Tamara Milovanovic Sanja Dragasevic Milica Stojkovic Lalosevic Sanja Zgradic Biljana Milicic Igor Dumic Stefan Kmezic Dusan Saponjski Andrija Antic Velimir Markovic Dragan Popovic Background and Objec
- Medicina, Vol. 55, Pages 694: Associations of Cardiovascular and All-Cause Mortality with Metabolic Syndrome in Hemodialysis Patients: A Prospective Single-Center StudyMedicina, Vol. 55, Pages 694: Associations of Cardiovascular and All-Cause Mortality with Metabolic Syndrome in Hemodialysis Patients: A Prospective Single-Center Study Medicina doi: 10.3390/medicina55100694 Authors: Zorica Dimitrijevic Andriana Jovanovic Mina Cvetkovic Tamara Vrecic Emina Kostic Branka Mitic Background and objectives: Metabolic syndrome (MetS) is a cluster of risk factors, such as abdominal obesity, i
- Medicina, Vol. 55, Pages 693: The Impact of High-Flow Nasal Cannula on the Outcome of Immunocompromised Patients with Acute Respiratory Failure: A Systematic Review and Meta-AnalysisMedicina, Vol. 55, Pages 693: The Impact of High-Flow Nasal Cannula on the Outcome of Immunocompromised Patients with Acute Respiratory Failure: A Systematic Review and Meta-Analysis Medicina doi: 10.3390/medicina55100693 Authors: Cheng Chang Wang Hsiao Lai Chao Background and objectives: High-flow nasal cannula (HFNC) can be used as a respiratory support strategy for patients with acute respiratory failure (ARF)
- Medicina, Vol. 55, Pages 692: Physical Strength Perception of Older Caregivers in Rural AreasMedicina, Vol. 55, Pages 692: Physical Strength Perception of Older Caregivers in Rural Areas Medicina doi: 10.3390/medicina55100692 Authors: Muñoz-Bermejo Villafaina Collado-Mateo Postigo-Mota Adsuar Background and objective: In an aging population, it is increasingly common for older adults to take care of other older adults. Caregiving tasks may be conditioned by the aging process. This study aims to analyze the p
- Medicina, Vol. 55, Pages 695: Effect of Muntingia calabura L. Stem Bark Extracts on Uric Acid Concentration and Renal Histopathology in Diabetic RatsMedicina, Vol. 55, Pages 695: Effect of Muntingia calabura L. Stem Bark Extracts on Uric Acid Concentration and Renal Histopathology in Diabetic Rats Medicina doi: 10.3390/medicina55100695 Authors: S. Safrida Mustafa Sabri Background and objectives: This study was designed to determine uric acid concentration and renal histopathology of Muntingia calabura L. stem bark extract in diabetic rats and to compare the natural product of
- Medicina, Vol. 55, Pages 691: Systemic and Local Factors’ Influence on the Topological Differences in Deep Vein ThrombosisMedicina, Vol. 55, Pages 691: Systemic and Local Factors’ Influence on the Topological Differences in Deep Vein Thrombosis Medicina doi: 10.3390/medicina55100691 Authors: Ştefan Cristian Vesa Romeo Chira Sonia Irina Vlaicu Sergiu Pașca Sorin Crișan Adrian Trifa Anca Dana Buzoianu Background and Objectives: Deep vein thrombosis (DVT) is a common cause of intra-hospital morbidity and mortality, and its most severe com
- Medicina, Vol. 55, Pages 690: Effectiveness of Warm-Up Routine on the Ankle Injuries Prevention in Young Female Basketball Players: A Randomized Controlled TrialMedicina, Vol. 55, Pages 690: Effectiveness of Warm-Up Routine on the Ankle Injuries Prevention in Young Female Basketball Players: A Randomized Controlled Trial Medicina doi: 10.3390/medicina55100690 Authors: Elvira Padua Agata Grazia D’Amico Anas Alashram Francesca Campoli Cristian Romagnoli Mauro Lombardo Matteo Quarantelli Emanuele Di Pinti Christian Tonanzi Giuseppe Annino Background and Objectives: An
- Membranes, Vol. 9, Pages 133: Preliminary Study of Emulsion Liquid Membrane Formulation on Acetaminophen Removal from the Aqueous PhaseMembranes, Vol. 9, Pages 133: Preliminary Study of Emulsion Liquid Membrane Formulation on Acetaminophen Removal from the Aqueous Phase Membranes doi: 10.3390/membranes9100133 Authors: Abdul Latif Ahmad Zulfida Mohamad Hafis Mohd Shafie Nur Dina Zaulkiflee Wen Yu Pang The aim of this study is to develop an Emulsion Liquid Membrane (ELM) system for the extraction of acetaminophen (ACTP). Firstly, ELM was formulated by the scr
- Metabolites, Vol. 9, Pages 233: Mitochondrial Dysfunction in the Transition from NASH to HCCMetabolites, Vol. 9, Pages 233: Mitochondrial Dysfunction in the Transition from NASH to HCC Metabolites doi: 10.3390/metabo9100233 Authors: Mélissa Léveillé Jennifer L. Estall The liver constantly adapts to meet energy requirements of the whole body. Despite its remarkable adaptative capacity, prolonged exposure of liver cells to harmful environmental cues (such as diets rich in fat, sugar, and cholesterol) results in the develop
- Metabolites, Vol. 9, Pages 234: Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis PatientsMetabolites, Vol. 9, Pages 234: Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients Metabolites doi: 10.3390/metabo9100234 Authors: La Rosa Johansen Molin Pseudomonas aeruginosa is one of the major causes of morbidity and mortality of cystic fibrosis patients. During the infection, the bacteria colonize the nutritional rich lung mucus, which is present in
- Metabolites, Vol. 9, Pages 231: Comparative Metabolomics Unravel the Effect of Magnesium Oversupply on Tomato Fruit Quality and Associated Plant MetabolismMetabolites, Vol. 9, Pages 231: Comparative Metabolomics Unravel the Effect of Magnesium Oversupply on Tomato Fruit Quality and Associated Plant Metabolism Metabolites doi: 10.3390/metabo9100231 Authors: Min Cheol Kwon Yangmin X. Kim Seulbi Lee Eun Sung Jung Digar Singh Jwakyung Sung Choong Hwan Lee In general, greenhouse cultivation involves the rampant application of chemical fertilizers, with the aim of achieving
- Metabolites, Vol. 9, Pages 232: Study of Fecal and Urinary Metabolite Perturbations Induced by Chronic Ethanol Treatment in Mice by UHPLC-MS/MS Targeted ProfilingMetabolites, Vol. 9, Pages 232: Study of Fecal and Urinary Metabolite Perturbations Induced by Chronic Ethanol Treatment in Mice by UHPLC-MS/MS Targeted Profiling Metabolites doi: 10.3390/metabo9100232 Authors: Olga Deda Christina Virgiliou Amvrosios Orfanidis Helen G. Gika Alcoholic liver disease (ALD) as a consequence of ethanol chronic consumption could lead to hepatic cirrhosis that is linked to high morbidity and mortal
- Metabolites, Vol. 9, Pages 230: Alterations in Exercise-Induced Plasma Adenosine Triphosphate Concentration in Highly Trained Athletes in a One-Year Training CycleMetabolites, Vol. 9, Pages 230: Alterations in Exercise-Induced Plasma Adenosine Triphosphate Concentration in Highly Trained Athletes in a One-Year Training Cycle Metabolites doi: 10.3390/metabo9100230 Authors: Ewa Anna Zarębska Krzysztof Kusy Ewa Maria Słomińska Łukasz Kruszyna Jacek Zieliński This study aimed to assess the effect of training loads on plasma adenosine triphosphate responsiveness in highly trained athlet
- Microorganisms, Vol. 7, Pages 466: Cows Get Crohn’s Disease and They’re Giving Us DiabetesMicroorganisms, Vol. 7, Pages 466: Cows Get Crohn’s Disease and They’re Giving Us Diabetes Microorganisms doi: 10.3390/microorganisms7100466 Authors: Coad Thomas Dow Leonardo A Sechi Increasingly, Johne’s disease of ruminants and human Crohn’s disease are regarded as the same infectious disease: paratuberculosis. Mycobacterium avium ss. paratuberculosis (MAP) is the cause of Johne’s and is the most commonly linke
- Microorganisms, Vol. 7, Pages 465: Intestinal Microbiota of Grass Carp Fed Faba Beans: A Comparative StudyMicroorganisms, Vol. 7, Pages 465: Intestinal Microbiota of Grass Carp Fed Faba Beans: A Comparative Study Microorganisms doi: 10.3390/microorganisms7100465 Authors: Lei Zhou Ke-tao Lin Lian Gan Ji-jia Sun Chang-jun Guo Li Liu Xian-de Huang Many reports of the intestinal microbiota of grass carp have addressed the microbial response to diet or starvation or the effect of microbes on metabolism; however, the intestin
- Microorganisms, Vol. 7, Pages 461: Global Burden of Colistin-Resistant Bacteria: Mobilized Colistin Resistance Genes Study (1980–2018)Microorganisms, Vol. 7, Pages 461: Global Burden of Colistin-Resistant Bacteria: Mobilized Colistin Resistance Genes Study (1980–2018) Microorganisms doi: 10.3390/microorganisms7100461 Authors: Elbediwi Li Paudyal Pan Li Xie Rajkovic Feng Fang Rankin Yue Colistin is considered to be an antimicrobial of last-resort for the treatment of multidrug-resistant Gram-negative bacterial infections. The
- Microorganisms, Vol. 7, Pages 462: Phylogenetic Analyses of Xanthomonads Causing Bacterial Leaf Spot of Tomato and Pepper: Xanthomonas euvesicatoria Revealed Homologous Populations Despite Distant Geographical DistributionMicroorganisms, Vol. 7, Pages 462: Phylogenetic Analyses of Xanthomonads Causing Bacterial Leaf Spot of Tomato and Pepper: Xanthomonas euvesicatoria Revealed Homologous Populations Despite Distant Geographical Distribution Microorganisms doi: 10.3390/microorganisms7100462 Authors: Dhakal Dobhal Alvarez Arif Bacterial leaf spot of tomato and pepper (BLS), an economically important bacterial disease caused by four species
- Microorganisms, Vol. 7, Pages 464: Genetic Diversity and Demographic History of Ganoderma boninense in Oil Palm Plantations of Sarawak, Malaysia Inferred from ITS RegionsMicroorganisms, Vol. 7, Pages 464: Genetic Diversity and Demographic History of Ganoderma boninense in Oil Palm Plantations of Sarawak, Malaysia Inferred from ITS Regions Microorganisms doi: 10.3390/microorganisms7100464 Authors: Midot Lau Wong Tung Yap Lo Jee Dom Melling Ganoderma boninense causes basal stem rot (BSR) and is responsible for substantial economic losses to Southeast Asia’s palm o
- Microorganisms, Vol. 7, Pages 460: Seroprevalence Study of Anti-HEV IgG among Different Adult Populations in Corsica, France, 2019Microorganisms, Vol. 7, Pages 460: Seroprevalence Study of Anti-HEV IgG among Different Adult Populations in Corsica, France, 2019 Microorganisms doi: 10.3390/microorganisms7100460 Authors: Capai Masse Gallian Souty Isnard Blanchon Peres de Lamballerie Charrel Falchi Hepatitis E virus (HEV) is a major cause of acute hepatitis worldwide. In France, hyperendemic areas including Corsica have an anti-
- Microorganisms, Vol. 7, Pages 455: Global Transcriptional Response of Three Highly Acid-Tolerant Field Strains of Listeria monocytogenes to HCl StressMicroorganisms, Vol. 7, Pages 455: Global Transcriptional Response of Three Highly Acid-Tolerant Field Strains of Listeria monocytogenes to HCl Stress Microorganisms doi: 10.3390/microorganisms7100455 Authors: Jule Anna Horlbog Marc J. A. Stevens Roger Stephan Claudia Guldimann Tolerance to acid is of dual importance for the food-borne pathogen Listeria monocytogenes: acids are used as a preservative, and gastric acid is one
- Microorganisms, Vol. 7, Pages 459: Pathogenetic Impact of Bacterial–Fungal InteractionsMicroorganisms, Vol. 7, Pages 459: Pathogenetic Impact of Bacterial–Fungal Interactions Microorganisms doi: 10.3390/microorganisms7100459 Authors: Filomena Nogueira Shirin Sharghi Karl Kuchler Thomas Lion Polymicrobial infections are of paramount importance because of the potential severity of clinical manifestations, often associated with increased resistance to antimicrobial treatment. The intricate interplay with the host
- Microorganisms, Vol. 7, Pages 463: Probiotics Prevents Sensitization to Oral Antigen and Subsequent Increases in Intestinal Tight Junction Permeability in Juvenile–Young Adult RatsMicroorganisms, Vol. 7, Pages 463: Probiotics Prevents Sensitization to Oral Antigen and Subsequent Increases in Intestinal Tight Junction Permeability in Juvenile–Young Adult Rats Microorganisms doi: 10.3390/microorganisms7100463 Authors: Tulyeu Kumagai Jimbo Watanabe Yokoyama Cui Osaka Mieno Yamagata Increased intestinal permeability is thought to underlie the pathogenesis of food allergy. We explo
- Microorganisms, Vol. 7, Pages 458: A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, VenezuelaMicroorganisms, Vol. 7, Pages 458: A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela Microorganisms doi: 10.3390/microorganisms7100458 Authors: Elizabeth McMahon Liliana Encinales Carlos Navarro Encinales Silvana Vielma Nelly Pacheco Lil Geraldine Avendaño Echavez Sandra Acosta Rodríguez Milena Calderon Silvia Encinales Sanabria Lorena Encinales S
- Microorganisms, Vol. 7, Pages 457: CRISPR/Cas9-Mediated Gene Replacement in the Fungal Keratitis Pathogen Fusarium solani var. petroliphilumMicroorganisms, Vol. 7, Pages 457: CRISPR/Cas9-Mediated Gene Replacement in the Fungal Keratitis Pathogen Fusarium solani var. petroliphilum Microorganisms doi: 10.3390/microorganisms7100457 Authors: Jorge D. Lightfoot Kevin K. Fuller Fungal keratitis (FK) is a site-threatening infection of the cornea associated with ocular trauma and contact lens wear. Members of the Fusarium solani species complex (FSSC) are predominant agents o
- Microorganisms, Vol. 7, Pages 456: Gut Microbiome Modulation Based on Probiotic Application for Anti-Obesity: A Review on Efficacy and ValidationMicroorganisms, Vol. 7, Pages 456: Gut Microbiome Modulation Based on Probiotic Application for Anti-Obesity: A Review on Efficacy and Validation Microorganisms doi: 10.3390/microorganisms7100456 Authors: Kaliyan Barathikannan Ramachandran Chelliah Momna Rubab Eric Banan-Mwine Daliri Fazle Elahi Dong-Hwan Kim Paul Agastian Seong-Yoon Oh Deog Hwan Oh The growing prevalence of obesity has become an important pro
- Molecules, Vol. 24, Pages 3742: The Combination of Whole Cell Lipidomics Analysis and Single Cell Confocal Imaging of Fluidity and Micropolarity Provides Insight into Stress-Induced Lipid Turnover in Subcellular Organelles of Pancreatic Beta CellsMolecules, Vol. 24, Pages 3742: The Combination of Whole Cell Lipidomics Analysis and Single Cell Confocal Imaging of Fluidity and Micropolarity Provides Insight into Stress-Induced Lipid Turnover in Subcellular Organelles of Pancreatic Beta Cells Molecules doi: 10.3390/molecules24203742 Authors: Giuseppe Maulucci Ofir Cohen Bareket Daniel Carla Ferreri Shlomo Sasson Modern omics techniques reveal molecular structures and
- Molecules, Vol. 24, Pages 3741: Aggregation State of Residual α-Helices and Their Influence on Physical Properties of S. c. ricini Native FiberMolecules, Vol. 24, Pages 3741: Aggregation State of Residual α-Helices and Their Influence on Physical Properties of S. c. ricini Native Fiber Molecules doi: 10.3390/molecules24203741 Authors: Kelvin O. Moseti Taiyo Yoshioka Tsunenori Kameda Yasumoto Nakazawa Formation of the α-helical conformation in the poly-l-alanine (PA) sequence regions, subsequent structural transition to β-sheet during natural spinning, an
- Molecules, Vol. 24, Pages 3740: Modulating Immune Response with Nucleic Acid NanoparticlesMolecules, Vol. 24, Pages 3740: Modulating Immune Response with Nucleic Acid Nanoparticles Molecules doi: 10.3390/molecules24203740 Authors: Jake K. Durbin Daniel K. Miller Julia Niekamp Emil F. Khisamutdinov Nano-objects made of nucleic acids are becoming promising materials in the biomedical field. This is, in part, due to DNA and RNA self-assembly properties that can be accurately computed to fabricate various complex nan
- Molecules, Vol. 24, Pages 3739: Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular ActivityMolecules, Vol. 24, Pages 3739: Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity Molecules doi: 10.3390/molecules24203739 Authors: Jianrong Sang Ketav Kulkarni Gabrielle M. Watson Xiuquan Ma David J. Craik Sónia T. Henriques Aaron G. Poth Aurélie H. Benfield Jacqueline A. Wilce Grb7 is an adapter protein, overexpressed
- Molecules, Vol. 24, Pages 3738: Synthesis and Cytotoxic Activity of New 1,3,4-Thiadiazole Thioglycosides and 1,2,3-Triazolyl-1,3,4-Thiadiazole N-glycosidesMolecules, Vol. 24, Pages 3738: Synthesis and Cytotoxic Activity of New 1,3,4-Thiadiazole Thioglycosides and 1,2,3-Triazolyl-1,3,4-Thiadiazole N-glycosides Molecules doi: 10.3390/molecules24203738 Authors: Alminderej Elganzory El-Bayaa Awad El-Sayed New 1,3,4-thiadiazole thioglycosides linked to substituted arylidine systems were synthesized via glycosylation of the prepared 1,3,4-thiadiazole thiol compounds. Click s
- Molecules, Vol. 24, Pages 3737: Natural Sesquiterpene Lactones of the 4,15-iso-Atriplicolide Type are Inhibitors of Trypanothione ReductaseMolecules, Vol. 24, Pages 3737: Natural Sesquiterpene Lactones of the 4,15-iso-Atriplicolide Type are Inhibitors of Trypanothione Reductase Molecules doi: 10.3390/molecules24203737 Authors: Lenz Krauth-Siegel Schmidt In the course of our investigations on the antitrypanosomal potential of sesquiterpene lactones (STL), we have recently reported on the exceptionally strong activity of 4,15-iso-Atriplicolide tiglate, which demo
- Molecules, Vol. 24, Pages 3736: Spider Chitin: An Ultrafast Microwave-Assisted Method for Chitin Isolation from Caribena versicolor Spider Molt CuticleMolecules, Vol. 24, Pages 3736: Spider Chitin: An Ultrafast Microwave-Assisted Method for Chitin Isolation from Caribena versicolor Spider Molt Cuticle Molecules doi: 10.3390/molecules24203736 Authors: Machałowski Wysokowski Tsurkan Galli Schimpf Rafaja Brendler Viehweger Żółtowska-Aksamitowska Petrenko Czaczyk Kraft Bertau Bechmann Guan Bornstein Voronkina Fursov Bej
- Molecules, Vol. 24, Pages 3735: Water Extracts of Hull-less Waxy Barley (Hordeum vulgare L.) Cultivar ‘Boseokchal’ Inhibit RANKL-induced OsteoclastogenesisMolecules, Vol. 24, Pages 3735: Water Extracts of Hull-less Waxy Barley (Hordeum vulgare L.) Cultivar ‘Boseokchal’ Inhibit RANKL-induced Osteoclastogenesis Molecules doi: 10.3390/molecules24203735 Authors: Kim Lee Son Lee Son Lee Lee Osteoporosis is a disease that leads to reduced bone mineral density. The increase in patient and medical costs because of global aging is recognized as a problem. Decreased bone
- Molecules, Vol. 24, Pages 3733: Two Novel Polysaccharides in Psoralea corylifolia L and anti-A549 Lung Cancer Cells Activity In VitroMolecules, Vol. 24, Pages 3733: Two Novel Polysaccharides in Psoralea corylifolia L and anti-A549 Lung Cancer Cells Activity In Vitro Molecules doi: 10.3390/molecules24203733 Authors: Zhenhua Yin Wei Zhang Juanjuan Zhang Huili Liu Qingfeng Guo Lin Chen Jinmei Wang Wenyi Kang Two novel water soluble heteroglycan (PCp-I and PCp-II) with anti-A549 lung cancer cells activity were isolated from Psoralea corylifolia L.
- Molecules, Vol. 24, Pages 3732: Preparation of Ganglioside GM1 by Supercritical CO2 Extraction and Immobilized SialidaseMolecules, Vol. 24, Pages 3732: Preparation of Ganglioside GM1 by Supercritical CO2 Extraction and Immobilized Sialidase Molecules doi: 10.3390/molecules24203732 Authors: Li Ji Zhonghui Qiao Xin Zhang Xiaolei Cheng Weiyang Wang Fan Zhang Yifa Zhou Ye Yuan Monosialotetrahexosylganglioside (GM1) has good activity on brain diseases and was developed to be a drug applied in clinics for neurological disorders and nerv
- Molecules, Vol. 24, Pages 3731: Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling PathwayMolecules, Vol. 24, Pages 3731: Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling Pathway Molecules doi: 10.3390/molecules24203731 Authors: Shaoxia Ye Qiyao Zheng Yang Zhou Bai Bai Depo Yang Zhimin Zhao The lindenane-type sesquiterpenoid chlojaponilactone B (1), isolated from Chloranthus japonicus, has been reported to posses
- Molecules, Vol. 24, Pages 3734: Co-Extraction and Co-Purification Coupled with HPLC-DAD for Simultaneous Detection of Acrylamide and 5-hydroxymethyl-2-furfural in Thermally Processed FoodsMolecules, Vol. 24, Pages 3734: Co-Extraction and Co-Purification Coupled with HPLC-DAD for Simultaneous Detection of Acrylamide and 5-hydroxymethyl-2-furfural in Thermally Processed Foods Molecules doi: 10.3390/molecules24203734 Authors: Jiaqi Shi Zeping Shao Honglei Li Yan Zhang Shuo Wang Acrylamide and 5-hydroxymethyl-2-furfural (5-HMF) are two of the most abundant compounds generated during thermal processing. A simpl
- Molecules, Vol. 24, Pages 3729: Evaluation of Chemical Composition of Two Linseed Varieties as Sources of Health-Beneficial SubstancesMolecules, Vol. 24, Pages 3729: Evaluation of Chemical Composition of Two Linseed Varieties as Sources of Health-Beneficial Substances Molecules doi: 10.3390/molecules24203729 Authors: Silvia Tavarini Antonella Castagna Giuseppe Conte Lara Foschi Chiara Sanmartin Luca Incrocci Annamaria Ranieri Andrea Serra Luciana G. Angelini Linseed (Linum usitatissimum L.) is becoming more and more important in the health f
- Molecules, Vol. 24, Pages 3723: 20(S)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of Panax notoginseng in ApoE Deficient MiceMolecules, Vol. 24, Pages 3723: 20(S)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of Panax notoginseng in ApoE Deficient Mice Molecules doi: 10.3390/molecules24203723 Authors: Conghui Liu Ruibing Feng Jian Zou Fangbo Xia Jian-Bo Wan Atherosclerosis mainly contributes to cardiovascular disease, a leading cause of global morbidity and mortality. Panax notoginseng saponins (PNS) are proved to t
- Molecules, Vol. 24, Pages 3728: Anticancer Indole-Based Chalcones: A Structural and Theoretical AnalysisMolecules, Vol. 24, Pages 3728: Anticancer Indole-Based Chalcones: A Structural and Theoretical Analysis Molecules doi: 10.3390/molecules24203728 Authors: Farid A. Badria Saied M. Soliman Saleh Atef Mohammad Shahidul Islam Abdullah Mohammed Al-Majid Necmi Dege Hazem A. Ghabbour M. Ali Fardous F. El-Senduny Assem Barakat The crystal structures of five new chalcones derived from N-ethyl-3-acetylindole with di
- Molecules, Vol. 24, Pages 3727: ε-Polylysine Inhibits Shewanella putrefaciens with Membrane Disruption and Cell DamageMolecules, Vol. 24, Pages 3727: ε-Polylysine Inhibits Shewanella putrefaciens with Membrane Disruption and Cell Damage Molecules doi: 10.3390/molecules24203727 Authors: Weiqing LAN Nannan ZHANG Shucheng LIU Mengling CHEN Jing XIE ε-Polylysine (ε-PL) was studied for the growth inhibition of Shewanella putrefaciens (S. putrefaciens). The minimal inhibitory concentration (MIC) of ε-PL against S. putre
- Molecules, Vol. 24, Pages 3726: Modulation of Adipogenesis and Oxidative Status by Quercetin and Ochratoxin A: Positive or Negative Impact on Rat Adipocyte Metabolism?Molecules, Vol. 24, Pages 3726: Modulation of Adipogenesis and Oxidative Status by Quercetin and Ochratoxin A: Positive or Negative Impact on Rat Adipocyte Metabolism? Molecules doi: 10.3390/molecules24203726 Authors: Viktoria Dobrocsyova Katarina Krskova Marcela Capcarova Stefan Zorad (1) Background: Impaired adipose tissue function leads to the development of metabolic disorders. Reactive oxygen species play a key role in
- Molecules, Vol. 24, Pages 3730: Constituents and Anti-Multidrug Resistance Activity of Taiwanofungus camphoratus on Human Cervical Cancer CellsMolecules, Vol. 24, Pages 3730: Constituents and Anti-Multidrug Resistance Activity of Taiwanofungus camphoratus on Human Cervical Cancer Cells Molecules doi: 10.3390/molecules24203730 Authors: Hsin-Yi Hung Chin-Chuan Hung Jun-Weil Liang Chin-Fu Chen Hung-Yi Chen Po-Chuen Shieh Ping-Chung Kuo Tian-Shung Wu Resistance to anti-cancer drugs is one of the main factors of treatment failure resulting in high morbidity.
- Molecules, Vol. 24, Pages 3724: Cellulose Nanocrystal Isolation from Hardwood Pulp using Various Hydrolysis ConditionsMolecules, Vol. 24, Pages 3724: Cellulose Nanocrystal Isolation from Hardwood Pulp using Various Hydrolysis Conditions Molecules doi: 10.3390/molecules24203724 Authors: Kuan-Hsuan Lin Toshiharu Enomae Feng-Cheng Chang To expand the application field of the pulping industry, this study conducted a series of sample preparations for processing cellulose nanocrystals (CNCs) from a dry hardwood pulp to achieve optimal sulfuric acid
- Molecules, Vol. 24, Pages 3725: Isoliquiritigenin Inhibits Ovarian Cancer Metastasis by Reversing Epithelial-to-Mesenchymal TransitionMolecules, Vol. 24, Pages 3725: Isoliquiritigenin Inhibits Ovarian Cancer Metastasis by Reversing Epithelial-to-Mesenchymal Transition Molecules doi: 10.3390/molecules24203725 Authors: Chen Chen Shuang Huang Chang-Liang Chen Sing-Bing Su Dong-Dong Fang The epithelial-to-mesenchymal transition (EMT) plays a prominent role in cancer metastasis. Isoliquiritigenin (ISL), one of the flavonoids in licorice, has been shown to ex
- Molecules, Vol. 24, Pages 3718: Metal-Organic Frameworks of MIL-100(Fe, Cr) and MIL-101(Cr) for Aromatic Amines Adsorption from Aqueous SolutionsMolecules, Vol. 24, Pages 3718: Metal-Organic Frameworks of MIL-100(Fe, Cr) and MIL-101(Cr) for Aromatic Amines Adsorption from Aqueous Solutions Molecules doi: 10.3390/molecules24203718 Authors: Mao-Long Chen Shu-Yang Zhou Zhou Xu Li Ding Yun-Hui Cheng MIL-100(Fe, Cr) and MIL-101(Cr) were synthesized by the hydrothermal method and applied to the adsorptions of five aromatic amines from aqueous solutions. These three meta
- Molecules, Vol. 24, Pages 3721: Prenylquinones in Human Parasitic Protozoa: Biosynthesis, Physiological Functions, and Potential as Chemotherapeutic TargetsMolecules, Vol. 24, Pages 3721: Prenylquinones in Human Parasitic Protozoa: Biosynthesis, Physiological Functions, and Potential as Chemotherapeutic Targets Molecules doi: 10.3390/molecules24203721 Authors: Ignasi B. Verdaguer Camila A. Zafra Marcell Crispim Rodrigo A.C. Sussmann Emília A. Kimura Alejandro M. Katzin Human parasitic protozoa cause a large number of diseases worldwide and, for some of these diseases, the
- Molecules, Vol. 24, Pages 3719: HU-671, a Novel Oleoyl Serine Derivative, Exhibits Enhanced Efficacy in Reversing Ovariectomy-Induced Osteoporosis and Bone Marrow AdiposityMolecules, Vol. 24, Pages 3719: HU-671, a Novel Oleoyl Serine Derivative, Exhibits Enhanced Efficacy in Reversing Ovariectomy-Induced Osteoporosis and Bone Marrow Adiposity Molecules doi: 10.3390/molecules24203719 Authors: Saja Baraghithy Reem Smoum Malka Attar-Namdar Raphael Mechoulam Itai Bab Joseph Tam Oleoyl serine (OS), an endogenous fatty acyl amide (FAA) found in bone, has been shown to have an anti-osteoporotic
- Molecules, Vol. 24, Pages 3720: A New Alkylation of Aryl Alcohols by Boron Trifluoride EtherateMolecules, Vol. 24, Pages 3720: A New Alkylation of Aryl Alcohols by Boron Trifluoride Etherate Molecules doi: 10.3390/molecules24203720 Authors: Ndze Denis Jumbam Yamkela Maganga Wayiza Masamba Nomthandazo I. Mbunye Esethu Mgoqi Sphumusa Mtwa The ethylation of aryl alcohols by an ethyl moiety of boron trifluoride etherate is described. The reaction proceeded cleanly and afforded good yields of the corresponding aryl e
- Molecules, Vol. 24, Pages 3722: Nitric Oxide Donor DETA/NO Inhibits the Growth of Endometrial Cancer Cells by Upregulating the Expression of RASSF1 and CDKN1AMolecules, Vol. 24, Pages 3722: Nitric Oxide Donor DETA/NO Inhibits the Growth of Endometrial Cancer Cells by Upregulating the Expression of RASSF1 and CDKN1A Molecules doi: 10.3390/molecules24203722 Authors: Sana Waheed Robert YS Cheng Yovanni Casablanca G. Larry Maxwell David A Wink Viqar Syed Nitric oxide (NO) is implicated in several biological processes, including cancer progression. At low concentrations, it prom
- Molecules, Vol. 24, Pages 3717: Synthesis of Lignin-based Phenol Terminated Hyperbranched PolymerMolecules, Vol. 24, Pages 3717: Synthesis of Lignin-based Phenol Terminated Hyperbranched Polymer Molecules doi: 10.3390/molecules24203717 Authors: Lionel Longe Gil Garnier Kei Saito In this work, we proved the efficient synthesis of a bio-based hyper-branched polyphenol from a modified lignin degradation fragment. Protocatechuic acid was readily obtained from vanillin, a lignin degradation product, via alkaline conditions, and
- Molecules, Vol. 24, Pages 3716: Recent Progress in the Development of Fluorescent Probes for ThiophenolMolecules, Vol. 24, Pages 3716: Recent Progress in the Development of Fluorescent Probes for Thiophenol Molecules doi: 10.3390/molecules24203716 Authors: Yuanqiang Hao Qianye Yin Yintang Zhang Maotian Xu Shu Chen Thiophenol (PhSH) belongs to a class of highly reactive and toxic aromatic thiols with widespread applications in the chemical industry for preparing pesticides, polymers, and pharmaceuticals. In this review, we
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