Antimicrobial activity of a novel polyherbal combination for the treatment of vaginal infection

Antimicrobial activity of a novel polyherbal combination for the treatment of vaginal infection: Shiv Kumar Yadav, Gaurav K Jain, Avijit Mazumder, Roop K Khar



Journal of Advanced Pharmaceutical Technology & Research 2019 10(4):190-194















The present study evaluated the antimicrobial activity of Azadirachta indica (AI), Cichorium intybus (CI), and Trigonella foenum-graecum (TFG) against bacterial and fungal pathogens responsible for the vaginal infections. The AI, CI, and TFG were selected to include antimicrobial and antifungal action against wide range of microbes. The different extracts of the herbs were evaluated for antibacterial and antifungal activity by well diffusion assays. Based on the results, the combination was selected and evaluated, “polyherbal antimicrobial (PHA).” The developed PHA extract demonstrated synergistic broad-spectrum antimicrobial activities including antibacterial and antifungal activity (minimum inhibition concentration: 5–7 mg/ml).