BioMed Research International
- Geographic Variations in Intertrochanteric Femoral Fractures in ChinaBackground. Hip fracture is one of the major risk factors of global mortality and disability. The aim of this study was to map the pattern of intertrochanteric femoral fractures in China, providing a pilot national dataset and basis for medical policy proposals. Methods. A multistage probability sampling strategy was applied in the national baseline survey. Thirty provinces in mainland China were included in this survey. A standardized questionna
- Study on miRNAs in Pan-Cancer of the Digestive Tract Based on the Illumina HiSeq System Data SequencingObjective. miRNA has gained attention as a therapeutic target in various malignancies. The proposal of this study was to investigate the biological functions of key miRNAs and target genes in cancers of the digestive tract which include esophageal carcinoma (ESCA), gastric adenocarcinoma (GAC), colon adenocarcinoma (COAD), and rectal adenocarcinoma (READ). Materials and Methods. After screening differentially expressed miRNAs (DEMIs) and differen
- Comparison between Minimally Invasive Plate Osteosynthesis and Conventional Open Plating for Midshaft Clavicle Fractures: A Systematic Review and Meta-AnalysisObjective. The aim of this study was to compare the functional outcome and complications in midshaft clavicle fractures receiving minimally invasive plate osteosynthesis and conventional open plating. Methods. Relevant studies were searched in the databases of Medline, EMBASE, Cochrane Library, Ovid, and Web of Science from inception to March 1, 2019. Pooled data were analyzed with Cochrane Collaboration’s Review Manager 5.3. Results. A total of
- Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat ModelBackground. Electroencephalography (EEG) is commonly used to assess the neurological prognosis of comatose patients after cardiac arrest (CA). However, the early prognostic accuracy of EEG may be affected by postresuscitation interventions. Recent animal studies found that hydrogen inhalation after CA greatly improved neurological outcomes by selectively neutralizing highly reactive oxidants, but the effect of hydrogen inhalation on EEG recovery
- Methods of Cryoprotectant Preservation: Allogeneic Cellular Bone Grafts and Potential EffectsDebridement of the bone surface during a surgical fusion procedure initiates an injury response promoting a healing cascade of molecular mediators released over time. Autologous grafts offer natural scaffolding to fill the bone void and to provide local bone cells. Commercial bone grafting products such as allografts, synthetic bone mineral products, etc., are used to supplement or to replace autologous grafts by supporting osteoinductivity, oste
- Helicobacter pylori Infection following Endoscopic Resection of Early Gastric CancerThe role of Helicobacter pylori (H. pylori) infection in patients following endoscopic resection of early gastric cancer (EGC) remains unclear. This article presents a review of literature published in the past 15 years. H. pylori‐mediated persistent methylation levels are associated with the development of metachronous gastric cancer. The methylation of certain specific genes can be used to identify patients with a high risk of metachronous gast
International Journal for Numerical Methods in Biomedical Engineering
- Parameter estimation to study the immediate impact of aortic cross‐clamping using reduced order modelsAbstract Aortic cross‐clamping is a common strategy during vascular surgery, however, its instantaneous impact on hemodynamics is unknown. We, therefore, developed two numerical models to estimate the immediate impact of aortic clamping on the vascular properties. To assess the validity of the models, we recorded continuous invasive pressure signals during abdominal aneurysm repair surgery, immediately before and after clamping. The first model
- Verification of the Coupled‐Momentum Method with Womersley's Deformable Wall Analytical SolutionAbstract In this paper, we perform a verification study of the Coupled‐Momentum Method (CMM), a 3D fluid‐structure interaction (FSI) model which uses a thin linear elastic membrane and linear kinematics to describe the mechanical behavior of the vessel wall. The verification of this model is done using Womersley's deformable wall analytical solution for pulsatile flow in a semi‐infinite cylindrical vessel. This solution is, under certain premise
- Issue InformationNo abstract is available for this article.
Medgadget
- Contact-Free Baby Monitor Uses White Noise to Monitor BreathingEcholocation technologies can detect objects by measuring how long it takes sound to bounce off them. This is used to detect submarines underwater, but now to also measure a child’s breathing while delivering soothing, and sleep inducing, white noise. Next week, researchers from the University of Washington will be at the MobiCom 2019 conference in Mexico to present their BreathJunior respiration monitor. The technology inside the device
- HairBoom Air FDA Cleared to Treat Hair LossWONTECH, a Korean company, won FDA clearance for its HairBoom Air hair loss treatment helmet. The device delivers low-power laser therapy to the scalp, bathing it in light. This kind of treatment has been shown to help increase blood flow around hair follicles, increasing oxygenation in nearby tissues, resulting in more hair growth and improved hair quality. The HairBoom Air, similar to the already available iGrow device,
- Alvo Medical Shows Off Its Vision of The Future of Operating Room DesignLocated in the picturesque town of Śmigiel, Poland, Alvo Medical is a family-run business that specializes in everything related to operating room layout and design. Since the company first started producing steel operating room furniture 25 years ago, Alvo has grown to become a worldwide provider of innovative healthcare solutions in the OR. During our recent visit to Poland, we had the opportunity to visit Alvo’s corporate offices and “C
Medical Image Analysis
- Prediction of final infarct volume from native CT perfusion and treatment parameters using deep learningPublication date: Available online 15 October 2019Source: Medical Image AnalysisAuthor(s): David Robben, Anna M.M. Boers, Henk A. Marquering, Lucianne L.C.M. Langezaal, Yvo B.W.E.M. Roos, Robert J. van Oostenbrugge, Wim H. van Zwam, Diederik W.J. Dippel, Charles B.L.M. Majoie, Aad van der Lugt, Robin Lemmens, Paul SuetensAbstractCT Perfusion (CTP) imaging has gained importance in the diagnosis of acute stroke. Conventional perfusion analysis perf
PeerJ Computer Science
- The phylogeny of desmostylians revisited: proposal of new clades based on robust phylogenetic hypothesesBackground Desmostylia is a clade of extinct aquatic mammals with no living members. Today, this clade is considered belonging to either Afrotheria or Perissodactyla. In the currently-accepted taxonomic scheme, Desmostylia includes two families, 10 to 12 genera, and 13–14 species. There have been relatively few phylogenetic analyses published on desmostylian interrelationship compared to other vertebrate taxa, and two main, altern
- Single-base-resolution methylome of giant panda’s brain, liver and pancreatic tissueThe giant panda (Ailuropoda melanoleuca) is one of the most endangered mammals, and its conservation has significant ecosystem and cultural service value. Cytosine DNA methylation (5mC) is a stable epigenetic modification to the genome and has multiple functions such as gene regulation. However, DNA methylome of giant panda and its function have not been reported as of yet. Bisulfite sequencing was performed on a 4-day-old male giant panda’s brai
- Identification of key genes and multiple molecular pathways of metastatic process in prostate cancerBackground Cancer metastasis is well known as the most adverse outcome and the major cause of mortality in cancer patients, including prostate cancer (PCa). There are no credible predictors, to this day, that can reflect the metastatic ability of localized PCa. In the present study, we firstly identified the differentially expressed genes (DEGs) and molecular pathways involved in the metastaic process of PCa by comparing gene expressions of met
- Relationships between key functional traits of the waterlily Nuphar lutea and wetland nutrient contentLittle attention has been paid to how aquatic habitat characteristics affect the traits of plant species. Nuphar lutea (L.) Sm. is a keystone species distributed across temperate regions of Europe, northwest Africa and western Asia. Its apparently low phenotypic variability compared to other aquatic plants led us to test whether the species exhibited significant phenotypic variability and whether trait values correlated to environmental parameter
- Rosiglitazone accelerates wound healing by improving endothelial precursor cell function and angiogenesis in db/db miceBackground & Aims Endothelial precursor cell (EPC) dysfunction is one of the risk factors for diabetes mellitus (DM) which results in delayed wound healing. Rosiglitazone (RSG) is a frequently prescribed oral glucose-lowering drug. Previous studies have shown the positive effects of RSG on ameliorating EPC dysfunction in diabetic patients. Interestingly, knowledge about RSG with regard to the wound healing process caused by DM is
- Differences between medically treated and untreated non-fatal self-harm reported by hotline callers in ChinaBackground Many self-harmers do not present in hospitals due to the self-harm. It is still unclear on the differences between medically treated and untreated self-harm in China. This study described the differences of the two groups of self-harmers using the largest psychological aid hotline data. Methods The present observational study recruited 3,403 hotline callers who reported episodes of self-harm before the call. In routine asse
- A novel form of wasp mimicry in a new species of praying mantis from the Amazon rainforest, Vespamantoida wherleyi gen. nov. sp. nov. (Mantodea, Mantoididae)A wasp mimicking praying mantis (Mantodea) of the early evolving Mantoididae family was discovered in 2013 at a research station near the Amazon River in Northern Peru. This adult specimen exhibited a striking bright red/orange and black coloration pattern that was undocumented in all known praying mantis species. We tested the status of this new specimen using external morphology, male genital dissections, and geographic distribution. Our findin
- Fundamental niche unfilling and potential invasion risk of the slider turtle Trachemys scriptaBackground How species colonize new environments is still a fundamental question in ecology and evolution, assessable by evaluating range characteristics of invasive species. Here we propose a model approach to evaluate environmental conditions and species features to predict niche changes in non-equilibrium contexts. It incorporates potentially range-limiting processes (fundamental niche), hence allowing for better predictions o
- Real-time reverse transcription polymerase chain reaction development for rapid detection of Tomato brown rugose fruit virus and comparison with other techniquesBackground Tomato brown rugose fruit virus (ToBRFV) is a highly infectious tobamovirus that causes severe disease in tomato (Solanum lycopersicum L.) crops. In Italy, the first ToBRFV outbreak occurred in 2018 in several provinces of the Sicily region. ToBRFV outbreak represents a serious threat for tomato crops in Italy and the Mediterranean Basin. Methods Molecular and biological characterisation of the Sicilian ToBRFV ToB-SIC01/19
- Comparison between two- and three-dimensional scoring of zebrafish response to psychoactive drugs: identifying when three-dimensional analysis is neededZebrafish (Danio rerio) have recently emerged as a valuable laboratory species in the field of behavioral pharmacology, where they afford rapid and precise high-throughput drug screening. Although the behavioral repertoire of this species manifests along three-dimensional (3D), most of the efforts in behavioral pharmacology rely on two-dimensional (2D) projections acquired from a single overhead or front camera. We recently showed that, compared
- Transcriptome analysis of the induction of somatic embryogenesis in Coffea canephora and the participation of ARF and Aux/IAA genesBackground Somatic embryogenesis (SE) is a useful biotechnological tool to study the morpho-physiological, biochemical and molecular processes during the development of Coffea canephora. Plant growth regulators (PGR) play a key role during cell differentiation in SE. The Auxin-response-factor (ARF) and Auxin/Indole-3-acetic acid (Aux/IAA) are fundamental components involved in the signaling of the IAA. The IAA signaling pathway a
- Lead isotope trends and sources in the atmosphere at the artificial wetlandWith the rapid development of industry, studies on lead pollution in total suspended particulate matter (TSP) have received extensive attention. This paper analyzed the concentration and pollution sources of lead in the Cuihu Wetland in Beijing during the period of 2016–2017. The results show that the lead contents in TSP in the Cuihu Wetland were approximately equal in summer and spring, greater in winter, and greatest in autumn. The correspondi
- Integumentary structure and composition in an exceptionally well-preserved hadrosaur (Dinosauria: Ornithischia)Preserved labile tissues (e.g., skin, muscle) in the fossil record of terrestrial vertebrates are increasingly becoming recognized as an important source of biological and taphonomic information. Here, we combine a variety of synchrotron radiation techniques with scanning electron and optical microscopy to elucidate the structure of 72 million-year-old squamous (scaly) skin from a hadrosaurid dinosaur from the Late Cretaceous of Alberta, Canada.
- Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, ChinaPRRS virus (PRRSV) has undergone rapid evolution and resulted in immense economic losses worldwide. In the present study, a PRRSV strain named FJ0908 causing high abortion rate (25%) and mortality (40%) was detected in a swine herd in China. To determine if a new PRRSV genotype had emerged, we characterized the genetic characteristics of FJ0908. Phylogenetic analysis indicated that FJ0908 was related to 1-7-4-like strains circulating in the Unite
- Effects of field-grown transgenic switchgrass carbon inputs on soil organic carbon cyclingGenetic engineering has been used to decrease the lignin content and to change the lignin composition of switchgrass (Panicum virgatum L.) to decrease cell wall recalcitrance to enable more efficient cellulosic biofuel production. Previous greenhouse and field studies showed that downregulation of the gene encoding switchgrass caffeic acid O-methyltransferase (COMT) and overexpression of the switchgrass PvMYB4 (MYB4) gene effectively improved eth
- The bZIP gene family in watermelon: genome-wide identification and expression analysis under cold stress and root-knot nematode infectionThe basic leucine zipper (bZIP) family transcription factors play crucial roles in regulating plant development and stress response. In this study, we identified 62 ClabZIP genes from watermelon genome, which were unevenly distributed across the 11 chromosomes. These ClabZIP proteins could be classified into 13 groups based on the phylogenetic relationships, and members in the same group showed similar compositions of conserved motifs and gene st
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