This cross-sectional study examines the association between site-neutral payment reform and otolaryngologists practicing within the Hospital Outpatient Prospective Payment System.
This case report describes a patient who presented with intractable cough after bilateral tympanostomy tube placement, which resolved after tube removal.
A woman in her 30s with a medical history of epilepsy and alcohol use disorder who was taking lamotrigine presented with severe head trauma. What is your diagnosis?
This diagnostic study describes an automated machine learning model that uses ultrasonographic images of thyroid lesions to identify and estimate genetic risk or status.
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These parents have had a bumpy journey, but they’ve found a way to make their careers and family life work
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B9Creations, the South Dakota-based manufacturer of the B9 Core Series of DLP 3D Printers, has launched a new additive manufacturing Healthcare Division & Service Bureau as well as a 3D printer targeted at the medical industry. The B9 Core Med 500, released with the first two of the company’s suite of biocompatible materials, will support […]
The venture capital arm of German specialty chemicals company Evonik has invested in 3D printing software startup Castor Technologies. A 2018 beneficiary of the STANLEY+Techstars Accelerator, Castor Technologies has developed a platform enabling customers to asses part printability, select the best material for purpose, and attain cost and lead time estimates. In addition to financial investment, Evonik will contribute its material […]
thyssenkrupp Innovations, the additive manufacturing arm of multinational conglomerate engineering group thyssenkrupp, has a new collaborator in the APAC region. Certification and qualification specialist TÜV SÜD, has signed an MoU with thyssenkrupp Innovations to help in the company’s development of a market for “additive-manufacturing-enabled solutions.” The agreement adds to a long list of partnerships thyssenkrupp Innovations […]
America Makes, the Ohio-based national accelerator for additive manufacturing, and the American National Standards Institute (ANSI) have released an online portal for tracking standardization activity in additive manufacturing. The interactive portal compiles the gaps in standards for additive manufacturing, identified through America Makes and ANSI’s Standardization Roadmap for Additive Manufacturing (Version 2.0) published in June […]
Leading 3D printer OEM 3D Systems has announced a partnership with Antleron, a Belgium-based biotechnology company, to develop regenerative products for personalized patient care. “The vision of Antleron is to sustainably bring living therapies into the clinic,” said Jan Schrooten, CEO of Antleron. “3D printing is key to this endeavor, and we are eager to collaborate with […]
Nebraska-based 3D printing materials manufacturer Tethon 3D has added a new patent to its IP portfolio. Granted October 22, 2019, the technology in question relates to a method of binder jet 3D printing for ceramics, metals, polymers or other powdered materials. Company President Trent Allen has called the patent grant “a proud moment” for the […]
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Abstract In Germany, the nationwide population-based mammography screening program (MSP) was introduced in 2005 and is full-running since 2010. By 2014, incidence rates for invasive breast cancer were very similar to those of the pre-screening era. Therefore, the ongoing effect of the MSP on breast cancer surgery rates can now be investigated. We analyzed population-based breast-conserving (BCS) and mastectomy (MET) surgery rates (per 100,000) among women aged < 50, 50–69 (eligible...
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Publication date: Available online 24 October 2019Source: International Journal of Food MicrobiologyAuthor(s): Vita Rozman, Petra Mohar Lorbeg, Tomaž Accetto, Bojana Bogovič MatijašićAbstractLactic acid bacteria and bifidobacteria deliberately introduced into the food chain may act as a reservoir of antimicrobial resistance genes (ARGs), which is considered a safety concern. In the present study, resistance to antimicrobials of commercial probiotic strains, probiotic candidate strains, and starter...
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Summary A large number of medical societies have issued recommendations for follow-up after primary treatment for early breast cancer, which mostly differ only in the details. The central statement in all of these guidelines has been based on two studies that were published in 1994 and came under criticism due to methodological flaws and the lack of modern diagnostic tools. This statement contains the merely symptom-induced search for distant metastasis and the rejection of routine...
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Publication date: December 2019Source: Cancer Epidemiology, Volume 63Author(s): A. Herbert, S. Winters, S. McPhail, L. Elliss-Brookes, G. Lyratzopoulos, G.A. AbelAbstractBackgroundDiagnosis of cancer through an emergency presentation is associated with worse clinical and patient experience outcomes. The proportion of patients with cancer who are diagnosed through emergency presentations has consequently been introduced as a routine cancer surveillance measure in England. Welcome reductions in this...
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Patients with N3 stage nasopharyngeal carcinoma (NPC) are at high risk for treatment failure. This study aims to assess the efficacy of maintenance chemotherapy (MC) using S-1 (MC-S1), a novel oral fluoropyrim...
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Abstract Background Interest in aqueous silver diamine fluoride (SDF) has been growing as a treatment for caries arrest. A cross-sectional study was conducted to identify factors associated with caregiver acceptance of SDF treatment for children presenting with caries at 8 Federally Qualified Health Centers. The study purpose was to examine associations between caregiver acceptance of SDF treatment for children with caries and (1)...
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External Volume Expansion Adjusted Adipose Stem Cell by Shifting the Ratio of Fibronectin to Laminin
Tissue Engineering Part A, Ahead of Print.
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AbstractBackgroundThe impact of activating alterations in non–small cell lung cancer (NSCLC) (epidermal growth factor receptor [EGFR] mutation/anaplastic lymphoma kinase [ALK] translocation) in prognosticating patients with brain metastasis (BM) is not well defined. This study was sought to identify this impact in NSCLC patients with BM accounting for the known validated variables.MethodsAmong 1078 NSCLC-BM patients diagnosed/treated between January 1, 2000 and December 31, 2015, three hundred and...
AbstractBackgroundThe Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW) has recommended that isocitrate dehydrogenase 1 and 2 wildtype (IDH1/2wt) diffuse lower-grade gliomas (LGGs) WHO grade II or III that present with a) a telomerase reverse transcriptase promoter mutation (pTERTmt), and/or b) gain of chromosome 7 combined with loss of chromosome 10, and/or c) epidermal growth factor receptor (EGFR) amplification should be reclassified as diffuse astrocytic...
AbstractBackgroundDiffuse intrinsic pontine gliomas (DIPGs) are highly lethal childhood brain tumors. Their unique genetic makeup, pathological heterogeneity, and brainstem location all present challenges to treatment. Developing mouse models that accurately reflect each of these distinct features will be critical to advance our understanding of DIPG development, progression, and therapeutic resistance. The aim of this study was to generate new mouse models of DIPG, and characterize the role of specific...
AbstractBackgroundGRP94 is a glucose-regulated protein critical for survival in endoplasmic reticulum stress. Expression of GRP94 is associated with cellular transformation and increased tumorigenicity in breast cancer. Specifically, over-expression of GRP94 predicts brain metastasis in breast carcinoma patients with either triple negative or ErbB2 positive tumors. The aim of this study was to understand if microenvironmental regulation of GRP94-expression might be a hinge orchestrating brain metastasis...
AbstractBackgroundDEPOSEIN (NCT01645839) was a randomized open-label phase III study to explore the role of intrathecal chemotherapy in patients with newly diagnosed leptomeningeal metastasis (LM), a common manifestation of breast cancer.MethodsPatients with newly diagnosed LM defined by tumor cells in the cerebrospinal fluid or combination of clinical and neuroimaging signs of LM were randomized to receive systemic therapy alone (control group) or systemic therapy plus intrathecal liposomal cytarabine...
AbstractBackgroundIsocitrate dehydrogenase (IDH) mutation status has emerged as an important prognostic marker in gliomas. Currently, reliable IDH mutation determination requires invasive surgical procedures. The purpose of this study was to develop a highly-accurate, MRI-based, voxel-wise deep-learning IDH-classification network using T2-weighted (T2w) MR images and compare its performance to a multi-contrast network.MethodsMulti-parametric brain MRI data and corresponding genomic information were...
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Summary Background Esophageal cancer is a very common malignant tumor in China, especially esophageal squamous cell carcinoma (ESCC), but there is currently no effective treatment for patients after first-line chemotherapy failure. Apatinib has shown promising outcomes in treatment with various solid tumors. Objectives To evaluate the clinical efficacy and safety of apatinib combined with S-1 in the treatment of advanced ESCC patients after first-line chemotherapy failure. Methods...
Summary Epithelial ovarian cancer (EOC) accounts for nearly 90% of all ovarian malignancies. The standard therapeutic strategy includes cytoreductive surgery and neo (adjuvant) platinum-based chemotherapy. Relapse of advanced high grade serous ovarian cancer (HGSOC) is related to the development of drug resistance. A defective DNA damage response is a defining hallmark of HGSOC. Poly (ADP-ribose) polymerase (PARP) inhibitors exploit this deficiency through synthetic lethality and...
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Dr. Eric Topol, a world-renowned cardiologist, considers the stethoscope obsolete, nothing more than a pair of "rubber tubes"
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Out at the farm, we wanted a way to enjoy a meal outdoors, so we made a picnic table with built in grills! Using fire bricks, grill parts, and pressure treated lumber, we made a simple, yet sturdy way to enjoy the outdoors. Subscribe to my channel: http://bit.ly/1k8msFr Second Channel: http://bit.ly/iltms-2 PICNIC TABLE PLANS: https://iliketomakestuff.com/shop/product/picnic-table-grill/ MITRE SAW STATION PLANS: https://iliketomakestuff.com/shop/product/miter-saw-station-digital-plans/ MORE...
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Additive Industries runs us through its history and plans for the future, dental is the key focus, we bring you the very best conversations from TCT Show 2019 & look ahead to Formnext.
13h
The Prague-based 3D printer manufacturer behind the popular Prusa desktop 3D printer line has introduced its latest and smallest machine to date.
13h
3D Systems has announced a collaboration with Belgian start-up Antleron to advance biomedical and “living therapy” engineering with 3D printing.
16h
Evonik Industries’ venture capital arm has invested in an Israeli software start-up which has developed a platform to assess the printability of part designs and the best material option.
17h
This world-leading summit will deliver unparalleled insight from internationally recognised blue-chip organisations, industry experts, renowned academics and market analysts.
18h
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The Food and Drug Administration is advising consumers not to purchase or use CholesLo, a product promoted and sold for lowering cholesterol on various websites, including www.choleslo.com, and possibly in some retail stores.
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Abstract Purpose The circadian clock plays an important role in many physiological states and pathologies. The significance of its core genes in bone formation and tooth development has already been demonstrated. However, regulation of these genes and their influence on periodontal and bone remodeling in periodontal ligament (PDL) fibroblasts remains to be elucidated. Our hypothesis was that the circadian clock influences markers...
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Publication date: Available online 23 October 2019Source: American Journal of OtolaryngologyAuthor(s): Gino Marioni, Giancarlo Ottaviano, Andrea Lovato, Leonardo Franz, Luigia Bandolin, Giacomo Contro, Luciano Giacomelli, Lara Alessandrini, Roberto Stramare, Cosimo de Filippis, Stella BlandamuraAbstractPurposeThe main aim of this study was to conduct a preliminary investigation into the possible relationship between mTOR and the nuclear tumor suppressor maspin in laryngeal carcinoma (LSCC).Materials...
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