ScienceDirect Publication: Talanta
- PET probe with Aggregation Induced Emission characteristics for the specific turn-on of aromatasePublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Renbo Wu, Song Liu, Yajing Liu, Yuli Sun, Hao Xiao, Yong Huang, Zequn Yang, Zehui WuAbstractAromatase is an attractive target for the diagnosis and treatment of breast cancer. To combine the anti-photobleaching properties of Aggregation Induced Emission (AIE) with the high sensitivity and whole-body imaging characteristics of positron emission tomography (PET), we designed a b
- Determination of endocrine disrupting chemicals in human nails using an alkaline digestion prior to ultra-high performance liquid chromatography–tandem mass spectrometryPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Laura Martín-Pozo, Samuel Cantarero-Malagón, Felix Hidalgo, Alberto Navalón, Alberto Zafra-GómezAbstractRapid industrialization has resulted in a progressive increase in human exposure to hazardous chemicals. The present work develops and validates a new method to determinate 18 endocrine disrupting chemicals (EDCs) in human nail samples. In contrast to other common biological
- Utilizing the thiol chemistry of biomolecules for the rapid determination of anti-TNF-α drug in bloodPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Saiqa Muneer, Godwin A. Ayoko, Nazrul Islam, Emad L. IzakeAbstractThe detection of anti-TNF-α drugs require rapid, selective and sensitive biosensors that can be easily utilised at the point of care. Herein, we demonstrate a new biosensing approach that employs target-specific nanomaterial and label free surface-enhanced Raman spectroscopy (SERS) for the selective extraction a
- In–spray chamber hydride generation by multi–mode sample introduction system (MSIS) as an interface in the hyphenated system of high performance liquid chromatography and inductivity coupled plasma optical emission spectrometry (HPLC/HG–ICP–OES) in arsenic species determinationPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Jędrzej Proch, Przemysław NiedzielskiAbstractThe paper presents a new usage of a commercial in–spray chamber hydride generator, Multi–mode Sample Introduction System (MSIS) as a connector of high pressure liquid chromatography and inductivity coupled plasma optical emission spectrometry (HPLC/HG–ICP–OES). This hyphenated technique was applied in a determination of inorganic an
- Mesoporous g-C<sub>3</sub>N<sub>4</sub>/β-CD nanocomposites modified glassy carbon electrode for electrochemical determination of 2,4,6-trinitrotoluenePublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Zhi-Wen Wang, Hong-Jin Liu, Chun-Yang Li, Xing Chen, Rohan Weerasooriya, Juan Wei, Jun Lv, Pin Lv, Yu-Cheng WuAbstractA novel method using mesoporous g-C3N4 and β-cyclodextrin nanocomposite (mpg-C3N4/β-CD) for the electrochemical detection of 2,4,6-trinitrotoluene (TNT) is presented. The unique structure of the mesoporous g-C3N4/β-CD nanocomposite facilitates both mpg-C3N4 ele
- Highly sensitive detection of ochratoxin A based on bio-barcode immunoassay and catalytic hairpin assembly signal amplificationPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Ruipeng Chen, Yunfeng Sun, Bingyang Huo, Shuai Yuan, Xuan Sun, Man Zhang, Na Yin, Longxing Fan, Wei Yao, Jiang Wang, Dianpeng Han, Shuang Li, Yuan Peng, Jialei Bai, Baoan Ning, Jun Liang, Zhixian GaoAbstractHerein, a highly sensitive ochratoxin A (OTA) detection strategy was developed based on a bio-barcode immunoassay with catalytic hairpin assembly (CHA). Two nanoprobes were
- Modelling sub-micron particle slip flow in liquid chromatographyPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Peter J. SkrdlaAbstractThe profoundly fast flow rates, observed at unexpectedly low column back-pressures, of capillaries packed with colloidal silica-based stationary phases is explained using slip flow theory applied to the particles themselves rather than the capillary walls. An equation is proposed that leverages nanoscale thermodynamics, geometrical considerations and Hag
- Parallel enrichment of polyphenols and phytosterols from <em>Pinot noir</em> grape seeds with molecularly imprinted polymers and analysis by capillary high-performance liquid chromatography electrospray ionisation tandem mass spectrometryPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Shima N.N.S. Hashim, Reinhard I. Boysen, Yuanzhong Yang, Lachlan J. Schwarz, Basil Danylec, Milton T.W. HearnAbstractThis investigation describes an integrated workflow for the parallel extraction and recovery of polyphenols and phytosterols from Pinot noir grape seeds. Using (E)-resveratrol and stigmasterol as exemplars, the approach employs two different molecular imprinted
- Digital image-based quantification of chlorpyrifos in water samples using a lipase embedded paper based devicePublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Karthikumar Sankar, D. Lenisha, G. Janaki, J. Juliana, R. Shyam Kumar, M. Chengathir Selvi, G. SrinivasanAbstractA paper-based device (PBD) for the detection of chlorpyrifos pesticide at field application was fabricated based on the principles of enzyme inhibition and image processing. Rhizopus niveus lipase, p-nitrophenol palmitate and Whatman No.1 paper were used as an enzym
- On-chip RT-LAMP and colorimetric detection of the prostate cancer 3 biomarker with an integrated thermal and imaging boxPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Lin-Xiang Wang, Jing-Jing Fu, Ying Zhou, Gang Chen, Can Fang, Zhi Song Lu, Ling YuAbstractTo achieve low-cost, compact, and portable nucleic acid testing, an integrated device containing a three-dimensional printing fabricated reverse transcription loop-mediated isothermal amplification (RT-LAMP) chip, a thermal module, and an imaging module was developed. Samples and RT-LAMP
- Copper(II) complex as a turn on fluorescent sensing platform for acetylcholinesterase activity with high sensitivityPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Peng Zhang, Caixia Fu, Yuzhe Xiao, Qian Zhang, Caifeng DingAbstractAcetylcholinesterase (AChE) is an important enzyme associated with many nervous diseases, demonstrating the great need for smarter sensing platform with improved sensitivity, selectivity and simplified operation. A “turn on” fluorometric assay is described herein for AChE activity detection, according to the sp
- Target and suspect screening of substances liable to migrate from food contact paper and cardboard materials using liquid chromatography-high resolution tandem mass spectrometryPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): L. Blanco-Zubiaguirre, I. Zabaleta, A. Usobiaga, A. Prieto, M. Olivares, O. Zuloaga, M.P. ElizaldeAbstractThis work describes the analysis of both target and non-target compounds in paper and cardboard materials together with the characterization of their migration to Tenax® by means of liquid chromatography coupled to both low (LC-QqQ) and high resolution tandem mass spectrom
- Analytical possibilities of Putrescine and Cadaverine enzymatic colorimetric determination in tuna based on diamine oxidase: A critical study of the use of ABTSPublication date: 1 February 2020Source: Talanta, Volume 208Author(s): Jesús Navarro, Isabel Sanz-Vicente, Rebeca Lozano, Susana de Marcos, Javier GalbánAbstractThe joint determination of putrescine (Put) and cadaverine (Cad) in the presence of other biogenic amines is studied using their enzymatic reaction with diamine oxidase (DAO). Three alternative methods are studied based on the intrinsic colorimetric properties of DAO or horseradish peroxi
Nature Communications - current - nature.com science feeds
- Meta-analysis of randomised controlled trials testing behavioural interventions to promote household action on climate changeNature Communications, Published online: 04 October 2019; doi:10.1038/s41467-019-12457-2It is not clear which are the most effective mechanisms to achieve sustainable lifestyle behaviour. Here the authors study the impact of behavioural interventions excluding economic incentives by performing a large-scale meta-analysis and find that these interventions promote sustainable behaviours to a small degree in the short-term with no evidence of sustai
- Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiationNature Communications, Published online: 04 October 2019; doi:10.1038/s41467-019-12103-xMyofibroblast differentiation contributes to extracellular matrix remodeling and fibrosis. Here, the authors report that alterations in mitochondrial calcium uptake is essential for metabolic reprogramming and epigenetic signaling for activation of the myofibroblast gene program.
- Observation of a phonon bottleneck in copper-doped colloidal quantum dotsNature Communications, Published online: 04 October 2019; doi:10.1038/s41467-019-12558-yWeak electron-phonon scattering that can enable long-lived hot electrons in semiconductors is of interest in hot carrier solar cells. Here, the authors report copper-doped colloidal cadmium-selenide quantum dots with hot electron lifetime extended by more than 30-fold compared to undoped dots.
- Adaptation of <i>Plasmodium falciparum</i> to humans involved the loss of an ape-specific erythrocyte invasion ligandNature Communications, Published online: 04 October 2019; doi:10.1038/s41467-019-12294-3Here, Proto et al. show that human infective Plasmodium falciparum isolates contain an inactivating mutation in the erythrocyte invasion associated gene PfEBA165, while homologues of ape-infective Laverania species are intact, and that expression of intact PfEBA165 is incompatible with parasite growth in human erythrocytes.
- Prebiotic condensation through wet–dry cycling regulated by deliquescenceNature Communications, Published online: 04 October 2019; doi:10.1038/s41467-019-11834-1Wet–dry cycling is regarded as a possible driving force of condensation reactions under prebiotic conditions. Here, the authors propose that water uptake by deliquescent minerals could have facilitated the wet phase and simulate this scenario using the oligomerization of glycine as a model reaction.
- Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytesNature Communications, Published online: 04 October 2019; doi:10.1038/s41467-019-12433-wArctigenin (ATG) is the major active component of a Chinese herbal remedy known to reduce proteinuria in patients with diabetic kidney disease (DKD). Here, Zhong et al. identify PP2A as a pharmacological target of ATG in podocytes, and find that PP2A is responsible for some of the beneficial effects of ATG in mouse models of DKD.
- Nanomechanical characterization of quantum interference in a topological insulator nanowireNature Communications, Published online: 04 October 2019; doi:10.1038/s41467-019-12560-4The density of states (DOS) of a topological insulator nanowire is expected to show Aharonov-Bohm (AB) oscillations, but they are never observed so far. Here, Kim et al. reveal AB oscillations in the DOS of a Bi2Se3 nanowire via nanomechanical resonance measurements.
- Author Correction: Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapyNature Communications, Published online: 04 October 2019; doi:10.1038/s41467-019-12198-2Author Correction: Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy
JoVE: Journal of Visualized Experiments
- Generation of Multicellular Human Primary Endometrial OrganoidsA protocol to generate human primary endometrial organoids that consist of epithelial and stromal cells and retain characteristics of the native endometrial tissue is presented. This protocol describes methods from uterine tissue acquisition to the histologic processing of endometrial organoids.
- Standardizing a Non-Lethal Method for Characterizing the Reproductive Status and Larval Development of Freshwater Mussels (Bivalvia: Unionida)Freshwater mussel conservation is dependent on monitoring reproductive patterns and processes of species. This study standardizes a non-lethal protocol for sampling gill contents, characterizing larval development, and providing a digital repository for data collected. This protocol-database package will be an important tool for mussel researchers in recovery of imperiled species.
- Perturbing Endothelial Biomechanics via Connexin 43 Structural DisruptionHere, we present a mechanics-based protocol to disrupt the gap junction connexin 43 and measure the subsequent impact this has on endothelial biomechanics via observation of tractions and intercellular stresses.
- Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene TherapyDescribed here is a protocol for characterizing modules of biologically synergistic miRNAs and their assembly into short transgenes, which allows simultaneous overexpression for gene therapy applications.
- A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural ProductsHere we present easy to use protocols for producing and purifying diterpenoid metabolites through the combinatorial expression of biosynthetic enzymes in Escherichia coli or Nicotiana benthamiana, followed by chromatographic product purification. The resulting metabolites are suitable for various studies including molecular structure characterization, enzyme functional studies, and bioactivity assays.
- Method Development for Contactless Resonant Cavity Dielectric Spectroscopic Studies of Cellulosic PaperA protocol for the non-destructive analysis of the fiber content and relative age of paper.
- Chronic Implantation of Multiple Flexible Polymer Electrode ArraysDescribed below is a method for implantation of multiple polymer electrode arrays across anatomically distant brain regions for chronic electrophysiological recording in freely moving rats. Preparation and surgical implantation are described in detail, with emphasis on design principles to guide adaptation of these methods for use in other species.
Journal of the American Chemical Society: Latest Articles (ACS Publications)
- [ASAP] Relaxation Dispersion NMR to Reveal Fast Dynamics in Brønsted Acid Catalysis: Influence of Sterics and H-Bond Strength on Conformations and Substrate HoppingJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b07841
- [ASAP] Scalable Production of Two-Dimensional Metallic Transition Metal Dichalcogenide Nanosheet Powders Using NaCl Templates toward Electrocatalytic ApplicationsJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b06044
- [ASAP] Quantitative Chiroptical Sensing of Free Amino Acids, Biothiols, Amines, and Amino Alcohols with an Aryl Fluoride ProbeJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b07588
- [ASAP] p-Metalated [1<sub>5</sub>]Paracyclophanes: Synthesis and Binding to Oxo-Anions via Anion-p InteractionsJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b09582
- [ASAP] Room Temperature Metallic Conductivity in a Metal–Organic Framework Induced by OxidationJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b06898
- [ASAP] Dynamic Covalent Switches and Communicating Networks for Tunable Multicolor Luminescent Systems and Vapor-Responsive MaterialsJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b07175
- [ASAP] A General Strategy for Engineering Noncanonical Amino Acid Dependent Bacterial GrowthJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b08491
- [ASAP] Reversibly Photoswitchable Fluorescent Diarylethenes Resistant against Photobleaching in Aqueous SolutionsJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b08748
- [ASAP] Adaptable Crosslinks in Polymeric Materials: Resolving the Intersection of Thermoplastics and ThermosetsJournal of the American Chemical SocietyDOI: 10.1021/jacs.9b07922
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