Publication date: Available online 22 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Lee L.Q. Pu
Wed Oct 23, 2019 16:09
Publication date: Available online 22 October 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): S.S. Subramaniam, C. Paterson, J.A. McCaulAbstractDespite many advances in surgery, radiotherapy, and systemic treatments, only modest improvements in survival, function, and quality of life have been achieved after treatment of squamous cell carcinoma (SCC) of the head and neck. With a better understanding of the biology and genetics of tumours, the emergence of a paradigm shift...
Wed Oct 23, 2019 16:05
Publication date: Available online 23 October 2019Source: Pathology - Research and PracticeAuthor(s): Anna Gabrych, Rafał Pęksa, Michał Kunc, Małgorzata Krawczyk, Ewa Izycka-Swieszewska, Wojciech Biernat, Ewa BieńAbstractBackgroundActivation of immune checkpoints, e.g. PD-1/PD-L1 axis, in cancer microenvironment, enables evasion of host anti-cancer immune response and drives tumor progression. To date, there have been only a few studies analyzing PD-1/PD-L1 expression in pediatric malignancies.AimIn...
Wed Oct 23, 2019 16:00
Publication date: Available online 23 October 2019Source: Pathology - Research and PracticeAuthor(s): Simona Gurzu, Annamaria Fetyko, Tivadar Bara, Laura Banias, Vlad Olimpiu Butiurca, Tivadar Bara, Vlad Tudorache, Ioan JungAbstractBackgroundMixed adenoneuroendocrine carcinoma (MANEC) is currently included in the category of neuroendocrine carcinomas but the therapeutically management is not yet defined.AimsTo present the immunohistochemical (IHC) features of the epithelial mesenchymal transition...
Wed Oct 23, 2019 16:00
Publication date: Available online 23 October 2019Source: Pathology - Research and PracticeAuthor(s): Lei Jiang, Wenyu Ge, Jingshu GengAbstractBackgroundMicroRNAs (miRNAs) have been proved to act as vital roles on non-small-cell lung cancer (NSCLC), and miR-425 has been proven to serve an important function in several tumors. However, the functional role of miR-425 on NSCLC is still unclear.MethodsThe mRNA and protein expression of miR-425 and AMPH-1 were determined by qRT-PCR and western blot analysis,...
Wed Oct 23, 2019 16:00
Publication date: Available online 22 October 2019Source: Pathology - Research and PracticeAuthor(s): Yue Li, Xiaoyan Cheng, Changlan Chen, Wu Huijuan, Hong Zhao, Wei Liu, Zheng Xiang, Qi WangAbstractHepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Apigenin was widely used in HCC treatment; however, the detailed mechanisms have not been clarified. We isolated, characterized, and identified Apigenin from the P. villosa plant using ethanol-extracted, semi-preparative...
Wed Oct 23, 2019 16:00
Publication date: Available online 22 October 2019Source: Pathology - Research and PracticeAuthor(s): Yue Zhao, Jake Maule, Yang Li, Jadee Neff, Chad M. McCall, Tie Hao, Weihong Yang, Catherine Rehder, Lian-He Yang, Endi WangAbstractHematolymphoid neoplasms, including lymphoma and myeloid neoplasms, can occur in patients with sickle cell disease (SCD) or equivalent hemoglobinopathy, but an underlying connection between the two conditions has yet to be fully determined. Herein, we report a unique...
Wed Oct 23, 2019 16:00
Edgar von Gierke (1877-1945) –Eponym of “von Gierke disease” and double victim of National Socialism
Publication date: Available online 22 October 2019Source: Pathology - Research and PracticeAuthor(s): Stephanie Kaiser, Janina Sziranyi, Dominik GrossAbstractAs recent studies on the Third Reich have shown, a three-digit number of Jewish pathologists fell victim to National Socialist repression. One of them was Edgar von Gierke. His name is nowadays best known in medicine for discovering the “von Gierke disease” – also classified as “Glycogen storage disease type I” – which he first described in...
Wed Oct 23, 2019 16:00
Publication date: November 2019Source: Dental Materials, Volume 35, Issue 11Author(s):
Wed Oct 23, 2019 15:59
Publication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Tao Yao, Qin Cui, Zhichao Liu, Cuifang Wang, Qi Zhang, Gaohua WangAbstractBackgroundDepression is a disease that seriously threatens the quality of human life. To explore the effect of gentiopicroside on depression, this study investigated the therapeutic effect of gentiopicroside on corticosterone-induced depressionin vivo and in vitro by using metabolomic methods.MethodsA total of 36 rats were randomly...
Wed Oct 23, 2019 15:59
215 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 23, 2019 15:58
215 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 23, 2019 13:56
Are electronic nicotine delivery systems (ENDs) helping cigarette smokers quit? – A current evidence
Abstract Background Electronic cigarettes (e‐cigarettes) and other electronic vaping devices are commonly used as a method to help tobacco smoking cessation. However, the data on their safety and efficacy is currently scarce. The aim of this review was to explore the role of e‐cigarettes in tobacco cessation among tobacco users. Types of Studies Reviewed PubMed, EMBASE, Scopus, Web of Science and grey literature from January 1990 were searched up to and including September 2018. Two independent...
Wed Oct 23, 2019 15:25
6114 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 23, 2019 15:53
6114 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 23, 2019 13:56
Purpose: This study investigated the clinical outcomes achieved with a newly developed donor inserter (NS Endo-Inserter [NSI], HOYA Co., Ltd., Tokyo, Japan) for Descemet’s stripping automated endothelial keratoplasty (DSAEK) in Japanese eyes with bullous keratopathy secondary to argon laser iridotomy (BK-ALI). The NSI device utilizes pressure flow to push the DSAEK donor tissue into the anterior chamber. Methods: Six eyes of 6 patients (1 male, 5 females; mean age, 78.5 years) with BK-ALI were enrolled....
Wed Oct 23, 2019 13:50
We report our findings in 3 cases of Creutzfeldt-Jakob disease (CJD) with visual disturbances as the initial manifestations. These cases were found to have the Heidenhain variant of CJD. Two cases initially presented with progressively blurred vision and homonymous hemianopia. The other case initially presented with blurred vision and a decrease in the central sensitivity in both eyes. These 3 cases developed neurological symptoms about 4 weeks after the onset of visual symptoms. All were diagnosed...
Wed Oct 23, 2019 13:49
Background: Multimodality treatment is increasingly accepted and becoming the standard care for local advanced esophageal cancer (EC) patients. However, for early stage lymph node-negative EC patients, surgery alone is still the primary treatment approach, and the role of perioperative chemotherapy remains unclear. Methods: Patients with lymph node-negative EC were identified from the Surveillance, Epidemiology, and End Results (SEER) database from 2004 to 2013. Survival was compared by the...
Tue Oct 22, 2019 03:00
Objectives: Approximately 8,300 new cases of anal carcinoma will be diagnosed in the United States in 2019. Anal squamous cell carcinoma (SCC) accounts for about 70% of all anal cancers. As cancer prevention and treatments have evolved over time, medical management of human immunodeficiency virus has improved, and sexual behaviors have changed, anal carcinoma incidence rates (IRs) may have also changed. Methods: The 9 oldest Surveillance, Epidemiology, and End Results registries were used...
Tue Oct 22, 2019 03:00
Objective: Long-lasting control is rarely achieved with tyrosine kinase inhibitors (TKI) alone in metastatic renal cell carcinoma (mRCC). Our study aimed to investigate the survival outcomes of adding stereotactic body radiotherapy (SBRT) to TKI in mRCC. Materials and Methods: From September 2015 to September 2018, 56 patients treated with TKI received SBRT for 103 unresectable lesions. A total of 24 and 32 patients were irradiated before and after TKI failure, respectively. Overall survival...
Tue Oct 22, 2019 03:00
Related ArticlesInfluence of reverse osmosis membrane age on rejection of NDMA precursors and formation of NDMA in finished water after full advanced treatment for potable reuse. Chemosphere. 2019 Oct;233:120-131 Authors: Roback SL, Ishida KP, Plumlee MH Abstract The influence of reverse osmosis (RO) membrane age on rejection of N-nitrosodimethylamine (NDMA) precursors was evaluated for a full-scale potable water reuse facility. The rejection of NDMA...
Wed Oct 23, 2019 15:48
Related ArticlesEvidence of vitamin D synthesis in insects exposed to UVb light. Sci Rep. 2018 Jul 17;8(1):10807 Authors: Oonincx DGAB, van Keulen P, Finke MD, Baines FM, Vermeulen M, Bosch G Abstract Vertebrates obtain the prohormone vitamin D primarily by endogenous cutaneous synthesis under ultraviolet b (UVb) exposure. To date, endogenous synthesis of vitamin D in insects has never been investigated. In an initial experiment, we exposed four insect...
Wed Oct 23, 2019 15:48
48 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 23, 2019 15:44
48 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 23, 2019 13:45
In Tanzania, waste stabilization ponds (WSPs) are employed to treat wastewater, and effluents are used for urban agricultural activities. The use of untreated or partially treated wastewater poses risks of disease transmission, including parasitic and bacterial infections, to exposed communities. Little is known about the occurrence, concentration, and removal of parasites and fecal coliform (FC) bacteria in WSPs in Tanzania. This study evaluates the occurrence and concentration of parasites and...
Wed Oct 23, 2019 15:05
Protium heptaphyllum is a plant widely distributed in Brazilian ecosystems that produce a resin which has pharmacological activities. In this study, the chemical composition, antimicrobial and antibiofilm activity, and the possible mechanism of action against the bacterium V. parahaemolyticus of essential oil from P. heptaphyllum (EOPH) were investigated. Twenty-two components were detected in EOPH, and β-phellandrene (60.68%) had the majority. The inhibition halo, MIC, and MBC values were 11 mm,...
Wed Oct 23, 2019 15:05
Related ArticlesBrave New (Microbial) World: implications for nasal and sinus disorders. Braz J Otorhinolaryngol. 2019 Sep 12;: Authors: Desrosiers M, Pereira Valera FC PMID: 31635980 [PubMed - as supplied by publisher]
Wed Oct 23, 2019 15:42
Publication date: Available online 22 October 2019Source: Radiotherapy and OncologyAuthor(s): Lisanne V. van Dijk, Lisa Van den Bosch, Paul Aljabar, Devis Peressutti, Stefan Both, Roel. J.H.M. Steenbakkers, Johannes A. Langendijk, Mark J. Gooding, Charlotte L. BrouwerAbstractIntroductionAdequate head and neck (HN) organ-at-risk (OAR) delineation is crucial for HN radiotherapy and for investigating the relationships between radiation dose to OARs and radiation-induced side effects. The automatic contouring...
Wed Oct 23, 2019 15:42
Publication date: Available online 22 October 2019Source: Radiotherapy and OncologyAuthor(s): Geneviève Van Ooteghem, Damien Dasnoy-Sumell, John Aldo Lee, Xavier GeetsAbstractBackground and purposeCurrent motion mitigation strategies, like margins, gating, and tracking, deal with geometrical uncertainties in the tumour position, induced by breathing during radiotherapy (RT). However, they often overlook motion variability in amplitude, respiratory rate, or baseline position, when breathing spontaneously....
Wed Oct 23, 2019 15:42
Publication date: Available online 23 October 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): I.A. Fernandes, G.M. Souza, V. Silva de Rezende, H.M. Al-Sharani, D.W. Douglas-de-Oliveira, E.L. Galvão, S.G.M. FalciAbstractThe aim of this systematic review was to verify whether the presence of a lower third molar in the mandibular angle fracture line is associated with postoperative complications. An electronic survey was conducted in five databases. Eligibility criteria...
Wed Oct 23, 2019 15:20
Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Moinay Kim, Seungjoo Lee, Jung Cheol Park, Dong-Min Jang, Seung Il Ha, Joung-Uk Kim, Jae Sung Ahn, Wonhyoung ParkBackgroundIndocyanine green (ICG) video angiography has been widely used in cerebrovascular surgery. ICG injection is generally safe, with a low incidence of complications. ICG-related anaphylactic reactions during neurosurgery have been rarely reported. We report the cases of 2 patients who had experienced...
Wed Oct 23, 2019 15:19
Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Gregory Glauser, Robert W. Hurst, Bryan A. Pukenas, Neda I. Sedora-Roman, David Kung, Omar ChoudhriBackgroundSubclavian steal phenomenon can cause retrograde flow in the vertebral artery as a result of ipsilateral occlusion of the subclavian artery. This phenomenon has various clinical presentations, such as claudication of the affected extremity or intermittent vertebrobasilar ischemia. Aneurysm formation in the spinal...
Wed Oct 23, 2019 15:19
Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Yangchun Li, Stephanie H. Chen, Dallas Sheinberg, Simon Buttrick, Corinna G. Levine, Rita G. Bhatia, Byron L. Lam, Joshua Pasol, Alejandro R. Ayala, Robert M. StarkeBackgroundSpindle cell oncocytomas (SCOs) are rare neuroendocrine tumors of the posterior pituitary that are often misdiagnosed as nonfunctional pituitary tumors. Fewer than 50 cases of SCOs have been described in the literature, and many of these reports have...
Wed Oct 23, 2019 15:19
Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Roshan George, Luvo Gaxa, Zarina Lockhat, Stevens Kgomotso Hlahla, Cornelis Hendrikus van der Meyden, Ravendran Kisten, Meshack BidaBackgroundBobble-head doll syndrome is a rare neurological syndrome presenting with repetitive anteroposterior head movements. It is usually associated with expansile cystic lesions in the third ventricular region.Case DescriptionAn 8-year-old boy presented with involuntary bobbling head movements....
Wed Oct 23, 2019 15:19
Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Yoichi Nonaka, Naokazu Hayashi, Mitsunori Matsumae, Takanori FukushimaBackgroundNeurosurgical micropatties (also known as sponges or cottonoids) have been used in microsurgical procedures to protect the brain surface and aspirate cerebrospinal fluid and blood. We sought to describe unique applications of micropatties in neurosurgical interventions.MethodsVarious sizes of micropatties have been used in neurosurgical interventions...
Wed Oct 23, 2019 15:19
Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Alberto Cacciola, Alfredo Conti, Francesco Tomasello
Wed Oct 23, 2019 15:19
Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Mithun G. Sattur, Alejandro M. SpiottaBackgroundThe middle meningeal artery (MMA) is an important conduit for the endovascular treatment of skull base and intracranial pathologies including, recently, subdural hematomas. A key aspect of such procedures is to perform a thorough diagnostic angiogram to detect anomalous arterial origins and “dangerous” anastomoses with branches of the internal carotid arteries. Although the...
Wed Oct 23, 2019 15:19
115 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 23, 2019 15:18
115 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Oct 23, 2019 13:22
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