Publication date: Available online 23 October 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Qionghui Wu, Yu Wang, Peng Wang, Zichao Xiang, Bin Ye, Jihua LiAbstractThis study aimed to compare the effectiveness and feasibility of inverted-L osteotomy (ILO) and sagittal split ramus osteotomy (SSRO) on obstructive sleep apnea (OSA) treatment. According to different surgery procedures, 28 OSA patients who underwent maxillomandibular advancement (MMA) were divided into 2 groups (group A:...
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Background and Aims. Recent data suggested a potential role of miR-143 as a biomarker for systemic inflammation and infection. However, its role in critical illness and sepsis is only poorly understood. Methods. We determined circulating levels of miR-143 in 218 critically ill patients, of which 135 fulfilled sepsis criteria, and compared them to 76 healthy controls. Results were correlated with clinical records. Results. In the total cohort of critically ill patients from a medical intensive care...
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Publication date: Available online 22 October 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Masoud Hassanzadeh Makoui, Danial Imani, Morteza Motallebnezhad, Maryam Azimi, Bahman RaziBackgroundDuring the last decade, several studies have evaluated the potential association between vitamin D receptor (VDR) gene polymorphism and susceptibility to asthma. In spite of valuable finding, the results are still contradictory. Therefore, a comprehensive meta-analysis not only solves discrepancies...
Publication date: Available online 22 October 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Susan Harvey, Susan M. O’Connell, Jonathan O’B Hourihane
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Hyaluronan (HA) and collagen are highly expressed in pancreatic cancer (PC) stroma. HA and collagen accumulation increase tumor interstitial fluid pressure, compromising blood flow and drug penetration. The aim of this biomarker study was to determine the clinical utility of serum HA and the propeptide of type III collagen (PRO‐C3) in patients with PC. A cohort from the Danish BIOPAC study (NCT03311776) including patients with histologically confirmed pancreatic ductal adenocarcinoma (n = 809), ampullary...
Complete and accurate registration of cancer is needed to provide reliable data on cancer incidence and to investigate aetiology. Such data can be derived from national cancer registries, but also from large population‐based cohort studies. As yet, the concordance and discordance between these two data sources remain unknown. We evaluated completeness and accuracy of cancer registration by studying the concordance between the population‐based Rotterdam Study (RS) and the Netherlands Cancer Registry...
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Urticaria is a condition defined by the development of wheals, angioedema or both. It is classified based on its duration as acute (≤ 6 weeks) or chronic (> 6 weeks). Chronic urticaria is less frequent than ac...
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Publication date: Available online 23 October 2019Source: Behavioural Brain ResearchAuthor(s): Ian Q Whishaw, Arashk Ghasroddashti, Behroo Mirza Agha, Majid H Mohajerani
Publication date: Available online 22 October 2019Source: Behavioural Brain ResearchAuthor(s): Rafaela Costa, Mariana Leite Tamascia, Andrea Sanches, Roseli Peres Moreira, Tatiana Sousa Cunha, Marie Doki Nogueira, Dulce Elena Casarini, Fernanda Klein MarcondesAbstractPhysical touch can help to decrease the effects of stress. The aim of this study was to evaluate the influence of tactile stimulation on the hormonal and behavioral responses of young adult rats submitted to chronic mild unpredictable...
Publication date: Available online 22 October 2019Source: Behavioural Brain ResearchAuthor(s): Shinji Takahashi, Ai Okamura, Mayako Yamazaki, Keni NiAbstractSchizophrenia is a major psychiatric disorder associated with positive and negative symptoms and cognitive impairments. In this study, we used animal models of behavior to evaluate the antipsychotic activity of ASP2905, a potent and selective inhibitor of the potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. ASP2905 inhibited hyperlocomotion...
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Cancers, Vol. 11, Pages 1626: Deregulated Lysophosphatidic Acid Metabolism and Signaling in Liver Cancer Cancers doi: 10.3390/cancers11111626 Authors: Kaffe Magkrioti Aidinis Liver cancer is one of the leading causes of death worldwide due to late diagnosis and scarcity of treatment options. The major risk factor for liver cancer is cirrhosis with the underlying causes of cirrhosis being viral infection (hepatitis B or C), metabolic deregulation (Non-alcoholic fatty liver disease...
Cancers, Vol. 11, Pages 1624: Adenylyl Cyclase Type 8 Overexpression Impairs Phosphorylation-Dependent Orai1 Inactivation and Promotes Migration in MDA-MB-231 Breast Cancer Cells Cancers doi: 10.3390/cancers11111624 Authors: Sanchez-Collado Lopez Jardin Camello Falcon Regodon Salido Smani Rosado Orai1 plays a major role in store-operated Ca2+ entry (SOCE) in triple-negative breast cancer (TNBC) cells. This channel is inactivated via different mechanisms,...
Cancers, Vol. 11, Pages 1623: Destined to Die: Apoptosis and Pediatric Cancers Cancers doi: 10.3390/cancers11111623 Authors: Choo Loh Chen Apoptosis (programmed cell death) is a systematic and coordinated cellular process that occurs in physiological and pathophysiological conditions. Sidestepping or resisting apoptosis is a distinct characteristic of human cancers including childhood malignancies. This review dissects the apoptosis pathways implicated in pediatric tumors. Understanding...
Cancers, Vol. 11, Pages 1625: Clinical Challenges and Consequences of Measurable Residual Disease in Non-APL Acute Myeloid Leukemia Cancers doi: 10.3390/cancers11111625 Authors: Madlen Jentzsch Sebastian Schwind Enrica Bach Sebastian Stasik Christian Thiede Uwe Platzbecker The ability to detect residual levels of leukemic blasts (measurable residual disease, MRD) has already been integrated in the daily routine for treatment of patients with chronic myeloid and acute lymphoblastic...
Cancers, Vol. 11, Pages 1621: Are ENT1/ENT1, NOTCH3, and miR-21 Reliable Prognostic Biomarkers in Patients with Resected Pancreatic Adenocarcinoma Treated with Adjuvant Gemcitabine Monotherapy? Cancers doi: 10.3390/cancers11111621 Authors: Lucie Jiraskova Ales Ryska Erik Jurjen Duintjer Tebbens Helena Hornychova Filip Cecka Frantisek Staud Lukas Cerveny Evidence on equilibrative nucleoside transporter 1 (ENT1) and microRNA-21 (miR‑21) is not yet sufficiently convincing...
Cancers, Vol. 11, Pages 1622: RAD52 Functions in Homologous Recombination and Its Importance on Genomic Integrity Maintenance and Cancer Therapy Cancers doi: 10.3390/cancers11111622 Authors: Augusto Nogueira Mara Fernandes Raquel Catarino Rui Medeiros Genomes are continually subjected to DNA damage whether they are induced from intrinsic physiological processes or extrinsic agents. Double-stranded breaks (DSBs) are the most injurious type of DNA damage, being induced by ionizing...
Cancers, Vol. 11, Pages 1620: The Pivotal Roles of the Epithelial Membrane Protein Family in Cancer Invasiveness and Metastasis Cancers doi: 10.3390/cancers11111620 Authors: Ahmat Amin Shimizu Ogita The members of the family of epithelial membrane proteins (EMPs), EMP1, EMP2, and EMP3, possess four putative transmembrane domain structures and are composed of approximately 160 amino acid residues. EMPs are encoded by the growth arrest-specific 3 (GAS3)/peripheral myelin protein...
Cancers, Vol. 11, Pages 1619: Theoretical and Practical Implications of Treating Cachexia in Advanced Lung Cancer Patients Cancers doi: 10.3390/cancers11111619 Authors: Philip Bonomi Mary Jo Fidler Palmi Shah Jeffrey Borgia Lung cancer continues to be a major worldwide health issue, with more than 50% of patients having incurable metastatic disease at diagnosis. Fortunately, the advanced lung cancer treatment landscape is changing rapidly as a result of the positive impact of...
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Publication date: Available online 22 October 2019Source: Journal of VoiceAuthor(s): Xinlin Xu, Peiyun Zhuang, Azure Wilson, Jack J. JiangSummaryObjectivesPrevious studies of subjects with unilateral vocal fold paralysis (UVFP) as observed in a positron emission tomography-computed tomography (PET-CT) examination have demonstrated false positive results in the contralateral cricoarytenoid, in which the metabolism may be higher. This area may also be the site of contralateral compensatory movement...
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During the past century, human life expectancy has nearly doubled globally, increasing by more years than it did in all previous millennia combined. Today, 617 million people are 65 years old or older; by 2050, the number will reach 1.6 billion — nearly 20% of the world’s population — and the…
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Please review the updated submission information here for the most current information about the SLA 2020 conference. Submission information The submission portal is now open. Abstracts are due by 3:00 pm Eastern Time on Monday, December 2, 2019. (This due date is revised from the original due date of December 1.) Session abstracts are limited to 500 words; paper and poster abstracts to 250 words. The fee scale for the SLA 2020 Spring Conference is: $130 (SLA Professional), $150 (Non-SLA Professional),...
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Sixty percent of patients with acute biliary disease who underwent early surgical intervention have a ‘complicated’ laparoscopic cholecystectomy (LC) and this is associated with worse post‐operative outcomes compared with ‘straightforward’ procedures. In order to schedule operations accurately and provide appropriate resources, the expected difficulty of an early LC can be assessed pre‐operatively using a simple prediction model based on the clinical diagnosis of acute cholecystitis, a positive Murphy's...
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Related ArticlesOverexpression of hypoxia-inducible factor 1α is associated with neutrophilic inflammation in chronic rhinosinusitis with nasal polyps. Auris Nasus Larynx. 2019 Oct 18;: Authors: Yu Z, Wang Y, Hu X, Xu H, Han M, Zhang J, Wen W, Shu H, Li H Abstract OBJECTIVE: This study aimed to assess the possible role of hypoxia-inducible factor 1α (HIF-1α) in promoting neutrophilic inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP) patients....
Related ArticlesIn-office procedures for the treatment of benign vocal fold lesions in the awake patient: A contemporary review. Laryngoscope. 2019 09;129(9):2131-2138 Authors: Shoffel-Havakuk H, Sadoughi B, Sulica L, Johns MM Abstract OBJECTIVES: To review available information regarding in-office procedures for benign vocal fold lesions (BVFL). METHODS: PubMed term search on office/awake laryngeal procedures for any of the following specific...
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Publication date: November 2019Source: Journal of Phonetics, Volume 77Author(s): Michael Proctor, Rachel Walker, Caitlin Smith, Tünde Szalay, Louis Goldstein, Shrikanth NarayananAbstractArticulation of liquid consonants in onsets and codas by four speakers of General American English was examined using real-time MRI. Midsagittal tongue posture was compared for laterals and rhotics produced in each syllable margin, adjacent to 13 different vowels and diphthongs. Vowel articulation was examined in...
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Publication date: December 2019Source: Cancer Epidemiology, Volume 63Author(s): Mayo Hirabayashi, Manami Inoue, Norie Sawada, Eiko Saito, Sarah K. Abe, Akihisa Hidaka, Motoki Iwasaki, Taiki Yamaji, Taichi Shimazu, Kenji Shibuya, Shoichiro Tsugane, for the JPHC Study GroupAbstractBackgroundBody fatness and weight gain are considered probable causes of gastric cancer, specifically in the cardia region. However, limited evidence is available in Asia, where the burden of gastric cancer is high. The objective...
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16 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Surg Neurol Int"[jour] These pubmed results were generated on 2019/10/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Abstract Background/purpose Optimal care for elderly patients with glioblastoma (GBM) remains in question due to their exclusion from and underrepresentation in many clinical trials (including EORTC 22,981) as well as their historically poor overall survival. Methods A retrospective chart review was conducted at a single high-volume cancer center for newly...
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Condition: Differentiated Thyroid CancerIntervention: Drug: Recombinant Human Thyroid Stimulating Hormone for InjectionSponsor: Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruiting
Condition: Nasopharyngeal CarcinomaInterventions: Drug: Cisplatin; Radiation: IMRTSponsors: Sun Yat-sen University; JiangXi Province Tumor Hospital; Fujian Province Tumor Hospital; SiChuan Province Tumor Hospital; Hunan Province Tumor Hospital; YuNan Province Tumor Hospital; GuiZhou Province Tumor Hospital; HaiNan Province Tumor Hospital; Affiliated TongJi hospital of HuaZhong University of science and Technology; Second Affiliated Hospital of Nanchang University; Wuhan University;...
Condition: Effect of Anesthesia on Head and Neck and Maxillofacial Surgery in Children After RecoveryInterventions: Drug: Folic acid; Drug: PlaceboSponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityNot yet recruiting
Conditions: Esophageal Neoplasms; Artificial Intelligence; Confocal Laser EndomicroscopyIntervention: Diagnostic Test: The diagnosis of Artificial Intelligence and endoscopistSponsor: Shandong UniversityRecruiting
Condition: Chronic Neck PainIntervention: Other: Neck COMISponsor: Cairo UniversityNot yet recruiting
Conditions: Breast Cancer; Thyroid CancerInterventions: Drug: Definity; Device: Acoustic AngiographySponsors: UNC Lineberger Comprehensive Cancer Center; National Cancer Institute (NCI)Not yet recruiting
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Abstract Background Several studies investigated the effects of caffeine supplementation on movement velocity in resistance exercise. However, these studies presented inconsistent findings. Objective This paper aimed to: (a) review the studies that explored the effects of caffeine supplementation on movement velocity in resistance exercise; and (b) pool their...
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Publication date: Available online 22 October 2019Source: Journal of Bodywork and Movement TherapiesAuthor(s): Elaheh Azadian, Mahdi Majlesi, Amir Ali Jafarnezhadgero, Urs GranacherAbstractIntroductionIn children, the impact of hearing loss on biomechanical gait parameters is not well understood. Thus, the objectives of this study were to examine three-dimensional lower limb joint torques in deaf compared to age-matched healthy (hearing) children while walking at preferred gait speed.MethodsThirty...
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