Nanomaterials, Vol. 9, Pages 1512: Inhibitory Activity of Silver Nanoparticles Synthesized Using Lycopersicon Esculentum against Biofilm Formation in Candida SpeciesNanomaterials, Vol. 9, Pages 1512: Inhibitory Activity of Silver Nanoparticles Synthesized Using Lycopersicon Esculentum against Biofilm Formation in Candida Species Nanomaterials doi: 10.3390/nano9111512 Authors: Jeong Su Choi Ji Woong Lee Un Chul Shin Min Woo Lee Dae Jin Kim Suhng Wook Kim This paper investigated the antifungal and...
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International Journal of Molecular Sciences , IJMS, Vol. 20, Pages 5264: The Role of Growth Hormone in Mesenchymal Stem Cell CommitmentIJMS, Vol. 20, Pages 5264: The Role of Growth Hormone in Mesenchymal Stem Cell Commitment International Journal of Molecular Sciences doi: 10.3390/ijms20215264 Authors: Bolamperti Guidobono Rubinacci Villa Growth hormone (GH) is best known for its prominent role in promoting prepubertal growth and in regulating body composition and metabolism during adulthood. In...
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International Journal of Environmental Research and Public Health , IJERPH, Vol. 16, Pages 4087: The Application of GSCM in Eliminating Healthcare Waste: Hospital EDC as an ExampleIJERPH, Vol. 16, Pages 4087: The Application of GSCM in Eliminating Healthcare Waste: Hospital EDC as an Example International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214087 Authors: Huan-Cheng Chang Mei-Chin Wang Hung-Chang Liao Ya-huei Wang Eliminating unnecessary healthcare waste in...
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Antibiotics, Vol. 8, Pages 192: The Fate of Bacteriophages in Recirculating Aquaculture Systems (RAS)—Towards Developing Phage Therapy for RASAntibiotics, Vol. 8, Pages 192: The Fate of Bacteriophages in Recirculating Aquaculture Systems (RAS)—Towards Developing Phage Therapy for RAS Antibiotics doi: 10.3390/antibiotics8040192 Authors: Gabriel M.F. Almeida Kati Mäkelä Elina Laanto Jani Pulkkinen Jouni Vielma Lotta-Riina Sundberg Aquaculture production has increased tremendously during the last decades,...
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Antibodies against ARHGDIB and ARHGDIB gene expression associate with kidney allograft outcomeBackground. The impact of donor-specific anti-HLA antibodies (DSA) on antibody-mediated rejection (AMR) and kidney allograft failure is well established. However, the relevance of non-HLA antibodies remains unclear. Methods. We investigated 13 pretransplant non-HLA antibodies and their association with histology of AMR (AMRh) and kidney allograft failure. We included single kidney recipients (N=203) with...
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Expression of maspin tumor suppressor and mTOR in laryngeal carcinomaAuthor links open overlay panelGinoMarioniaGiancarloOttavianoaAndreaLovatobLeonardoFranzaLuigiaBandolinaGiacomoControaLucianoGiacomellicLaraAlessandrinicRobertoStramaredCosimode FilippiscStellaBlandamuracaDepartment of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, ItalybDepartment of Neuroscience DNS, Audiology Unit, University of Padova, Treviso, ItalycDepartment of Medicine DIMED, University of Padova,...
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Pulmonary Artery/Vein Separation Using Single-Phase Computed Tomography: Feasibility and the Influence of Patient Characteristics on Vessel EnhancementPurpose: The purpose of this article was to verify the usefulness and feasibility of a single-phase scan for pulmonary artery/vein separation using a bolus-tracking technique and to evaluate the influence of patient characteristics on differentiation of computed tomography (CT) values between arteries and veins. Material and Methods: A total of 79...
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Provider Consensus on Candidate Protective and Risk Factors for Adverse Psychosocial Outcomes Following Discharge From a PICU: A Modified Delphi StudyObjectives: Pediatric palliative care promotes interdisciplinary, family-centered care when children are faced with diagnoses threatening length and/or quality of life. A significant knowledge gap remains in how to best match pediatric palliative care resources to palliate the psychosocial impact of a PICU admission. This study was designed to identify...
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Multi-frequency Electrocochleography Measurements can be Used to Monitor and Optimize Electrode Placement During Cochlear Implant SurgeryObjective: To report the use of multi-frequency intra-cochlear electrocochleography (ECOG) in monitoring and optimizing electrode placement during cochlear implant surgery. An acoustic pure tone complex comprising of 250, 500, 1000, and 2000 Hz was used to elicit ECOG, or more specifically cochlear microphonics (CMs), responses from various locations in the cochlea....
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The Importance of Imaging Informatics and Informaticists in the Implementation of AIPublication date: Available online 19 October 2019Source: Academic RadiologyAuthor(s): Tessa S. CookImaging informatics is critical to the success of AI implementation in radiology. An imaging informaticist is a unique individual who sits at the intersection of clinical radiology, data science, and information technology. With the ability to understand each of the different domains and translate between the experts...
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Sexual Abuse and Future Mental Health Hospitalization in a Swedish National Sample of Men Who Use OpioidsObjective: Experiences of trauma, specifically sexual abuse, have been linked to both mental health and substance use disorders. This study used 14 years of Swedish health registry data to select a sample of adult men who reported frequent opioid use and assessed if those with a self-reported history of sexual abuse had a higher likelihood of hospitalization for a mental health disorder. Methods:...
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Pain monitor: reality or fantasy in ambulatory patientsPurpose of review In an unconscious patient, there can be significant challenges to monitoring nociception and proper dosing of analgesic medications. The traditional measures of intraoperative nociception have poor sensitivity and specificity with little predictive value in postoperative outcomes such as postoperative pain, opioid-induced side effects, length of stay or incidence of opioid use disorder. To date, several monitoring modalities...
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Myths about breastfeedingHussein KouraAl-Azhar Assiut Medical Journal 2019 17(2):109-113Breastfeeding is an unparalleled way of providing ideal food for healthy growth and development of the infant through its unique biological and emotional influences. WHO recommends exclusive breastfeeding for the first 6 months of an infant’s life, with continued breastfeeding and complementary feeding introduced after the first 6 months up to the age of 2 years. Many factors affect breastfeeding, and they can...
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Serum uric acid and fatal myocardial infarction: detection of prognostic cut-off values: The URRAH (Uric Acid Right for Heart Health) studyObjective: The Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension conceived and designed an ad-hoc study aimed at searching for prognostic cut-off values of serum uric acid (SUA) in predicting fatal myocardial infaction (MI) in women and men. Methods: The URic acid Right for heArt Health study is a nationwide, multicentre,...
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Does Repeated Painful Stimuli Change Cerebral Near-infrared Spectroscopy Response in Healthy Term Large for Gestational Age Newborns?Objective: To evaluate the effect of repeated painful stimuli on short-term pain response in healthy, term, large for gestational age (LGA) newborns by measuring the regional cerebral oxygen saturation (rScO2), behavioral and physiological responses. Methods: We compared term LGA infants who received repeated painful stimuli (study group) to term, appropriate for gestational...
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Very Low Density Lipoprotein Receptor Sequesters Lipopolysaccharide Into Adipose Tissue During SepsisObjectives: Obese patients have lower sepsis mortality termed the “obesity paradox.” We hypothesized that lipopolysaccharide, known to be carried within lipoproteins such as very low density lipoprotein, could be sequestered in adipose tissue during sepsis; potentially contributing a survival benefit. Design: Retrospective analysis. Setting: University research laboratory. Subjects and Patients: Vldlr...
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Bronchoscopy for Chronic Unexplained Cough: Use of Biopsies and Cultures Increase Diagnostic YieldBackground: Prior studies assessing the diagnostic utility of bronchoscopy for chronic unexplained cough have focused primarily on identifying endobronchial anomalies to determine chronic cough etiology. On the basis of our institutional experience, expanding bronchoscopy to include cultures and biopsies can considerably increase its diagnostic yield for identifying the etiology of chronic unexplained...
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Myocardial Phosphodiesterases and their Role in cGMP RegulationCyclic nucleotide phosphodiesterases comprise an 11-member superfamily yielding near 100 isoform variants that hydrolyze cAMP or cGMP to their respective 5’-monophosphate form. Each plays a role in compartmentalized cyclic nucleotide signaling, with varying selectivity for each substrate, and conveying cell and intracellular specific localized control. This review focuses on the five PDEs expressed in the cardiac myocyte capable of hydrolyzing...
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Vortioxetine-Related Call–Fleming SyndromeNo abstract availableTreatment Failures of Direct Oral AnticoagulantsBackground: Use of direct oral anticoagulants (DOACs) has increased over the years, because they have become a safe and effective alternative to the Vitamin-K antagonists in various clinical scenarios. With their increased use, reports have emerged describing their failure. Study Question: What are the patient characteristics and clinical settings in which DOAC treatment failure manifests?...
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Mixing-based inhibitor screening in haemophilia A: challenges in interpretationInhibitor development in haemophilia A patients is a dreaded complication of factor VIII (FVIII) replacement therapy. With increasing use of FVIII replacement therapy, there is an imperative need for cost-effective and standardized screening. To evaluate the efficacy of mixing-based inhibitor screening (MBIS) in the detection of FVIII inhibitors and to assess the best cut-off values for MBIS. Forty inhibitor positive and...
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Clinical outcomes post transition to adult services in young adults with perinatally acquired HIV infection: mortality, retention in care, and viral suppressionObjective: Adolescence is the only age group globally where HIV associated mortality is rising, with poorer outcomes at all stages of the care cascade compared to adults. We examined post-transition outcomes for young adults living with perinatal HIV (YAPaHIV). Design: Retrospective cohort analysis. Setting: A tertiary Youth Friendly Service...
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Droplet digital polymerase chain reaction offers an improvisation over conventional immunohistochemistry and fluorescent in situ hybridization for ascertaining Her2 status of breast cancerMoushumi Suryavanshi, Jiten Jaipuria, Anurag Mehta, Dushyant Kumar, Manoj Kumar Panigrahi, Haristuti Verma, Mumtaz Saifi, Sanjeev Sharma, Simran Tandon, Dinesh Chandra Doval, Bhudev C DasSouth Asian Journal of Cancer 2019 8(4):203-210Background: Droplet digital polymerase chain reaction (DDPCR) is a recent modality...
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CDC Travelers' Health Update , Travelers’ diarrhea (TD) is the most common travel-related illness.In otherwise healthy adults, TD is rarely serious or life-threatening, but it can certainly make for an unpleasant trip. Take steps to avoid TD when you travel. Full article.Prevent• Only drink water that you know is safe; otherwise, stick to bottled or boiled drinks. Avoid ice.• Only eat food that is cooked and served hot, peeled by you, or factory-sealed. Self-Treatment• Drink fluids.• Consider...
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The epididymal immune balance: a key to preserving male fertilityAllison Voisin, Fabrice Saez, Joël R Drevet, Rachel GuitonAsian Journal of Andrology 2019 21(6):531-539Up to 15% of male infertility has an immunological origin, either due to repetitive infections or to autoimmune responses mainly affecting the epididymis, prostate, and testis. Clinical observations and epidemiological data clearly contradict the idea that the testis confers immune protection to the whole male genital tract. As a consequence,...
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Interactions of ginseng with therapeutic drugsAuthors:Min-Koo Choi and Im-Sook SongContent type:Review31 August 2019Warburg effect and its role in tumourigenesisAuthors:Maphuti T. Lebelo, Anna M. Joubert and Michelle H. VisagieContent type:Research Article19 August 2019Pifithrin-μ induces necroptosis through oxidative mitochondrial damage but accompanies epithelial–mesenchymal transition-like phenomenon in malignant mesothelioma cells under lactic acidosisAuthors:Yoon-Jin Lee, Kwan-Sik Park, Su-Hak...
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A Common Frame for Formal ImaginationAuthors:Joan Casas-Roma, M. Elena Rodríguez and Antonia HuertasContent type:OriginalPaper15 October 2019A Misdirected Principle with a Catch: Explicability for AIAuthors:Scott RobbinsContent type:Commentary11 October 2019Ethics of AI and Cybersecurity When Sovereignty is at StakeAuthors:Paul TimmersContent type:OriginalPaper21 September 2019The Rhetoric and Reality of Anthropomorphism in Artificial IntelligenceAuthors:David WatsonContent type:Original Article30...
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KAT2A succinyltransferase activity-mediated 14-3-3ζ upregulation promotes β-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cellsPublication date: 28 January 2020Source: Cancer Letters, Volume 469Author(s): Yingying Tong, Dong Guo, Dong Yan, Chunmin Ma, Fei Shao, Yugang Wang, Shudi Luo, Liming Lin, Jingjing Tao, Yuhui Jiang, Zhimin Lu, Dongming XingAbstractFrequently occurring histone lysine succinylation is a newly identified histone modification that can be...
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Practitioner Perceptions of Evidence-Based Practice in Elite Sport in the United States of AmericaFullagar, HHK, Harper, LD, Govus, A, McCunn, R, Eisenmann, J, and McCall, A. Practitioner perceptions of evidence-based practice in elite sport in the United States of America. J Strength Cond Res 33(11): 2897–2904, 2019—Practitioners' perceptions regarding the use and effectiveness of research evidence in sport is not well understood. The purpose of the present study was to examine practitioners' perceptions...
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