IJMS, Vol. 20, Pages 5264: The Role of Growth Hormone in Mesenchymal Stem Cell Commitment International Journal of Molecular Sciences doi: 10.3390/ijms20215264 Authors: Bolamperti Guidobono Rubinacci Villa Growth hormone (GH) is best known for its prominent role in promoting prepubertal growth and in regulating body composition and metabolism during adulthood. In recent years, the possible role of GH in the modulation of mesenchymal stem cell (MSC) commitment has gained...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5260: Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development International Journal of Molecular Sciences doi: 10.3390/ijms20215260 Authors: El Hadidy Uversky The two-meter-long DNA is compressed into chromatin in the nucleus of every cell, which serves as a significant barrier to transcription. Therefore, for processes such as replication and transcription to occur, the highly compacted chromatin must be relaxed, and the...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5259: Cell Wall Proteins Play Critical Roles in Plant Adaptation to Phosphorus Deficiency International Journal of Molecular Sciences doi: 10.3390/ijms20215259 Authors: Weiwei Wu Shengnan Zhu Qianqian Chen Yan Lin Jiang Tian Cuiyue Liang Phosphorus is one of the mineral nutrient elements essential for plant growth and development. Low phosphate (Pi) availability in soils adversely affects crop production. To cope with low P stress, remodeling of root...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5257: Polyunsaturated Fatty Acids: What is Their Role in Treatment of Psychiatric Disorders? International Journal of Molecular Sciences doi: 10.3390/ijms20215257 Authors: Bozzatello Rocca Mantelli Bellino In the central nervous system omega-3 fatty acids modulate cell signaling and affect dopaminergic and serotonergic pathways. On this basis, a new application for omega-3 fatty acids has been proposed, concerning the treatment of several psychiatric...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5258: Zinc Homeostasis in Platelet-Related Diseases International Journal of Molecular Sciences doi: 10.3390/ijms20215258 Authors: Elmina Mammadova-Bach Attila Braun Zn2+ deficiency in the human population is frequent in underdeveloped countries. Worldwide, approximatively 2 billion people consume Zn2+-deficient diets, accounting for 1–4% of deaths each year, mainly in infants with a compromised immune system. Depending on the severity of Zn2+ deficiency,...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5253: Evidence for Nanoparticle-Induced Lysosomal Dysfunction in Lung Adenocarcinoma (A549) Cells International Journal of Molecular Sciences doi: 10.3390/ijms20215253 Authors: Arnold Sipos Kwang-Jin Kim Constantinos Sioutas Edward D. Crandall Background: Polystyrene nanoparticles (PNP) are taken up by primary rat alveolar epithelial cell monolayers (RAECM) in a time-, dose-, and size-dependent manner without involving endocytosis. Internalized PNP in RAECM...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5256: Citrus Genetic Engineering for Disease Resistance: Past, Present and Future International Journal of Molecular Sciences doi: 10.3390/ijms20215256 Authors: Lifang Sun Nasrullah Fuzhi Ke Zhenpeng Nie Ping Wang Jianguo Xu Worldwide, citrus is one of the most important fruit crops and is grown in more than 130 countries, predominantly in tropical and subtropical areas. The healthy progress of the citrus industry has been seriously affected by biotic...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5254: Novel Crosstalks between Circadian Clock and Jasmonic Acid Pathway Finely Coordinate the Tradeoff among Plant Growth, Senescence and Defense International Journal of Molecular Sciences doi: 10.3390/ijms20215254 Authors: Yuanyuan Zhang Cunpei Bo Lei Wang Circadian clock not only functions as a cellular time-keeping mechanism, but also acts as a master regulator to coordinate the tradeoff between plant growth and defense in higher plants by timing a few...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5251: Presence of 15p Marker D15Z1 on the Short Arm of Acrocentric Chromosomes is Associated with Aneuploid Offspring in Mexican Couples International Journal of Molecular Sciences doi: 10.3390/ijms20215251 Authors: Sandra Ramos Rebeca Rodríguez Oscar Castro Patricia Grether Bertha Molina Sara Frias Variation in the location of the 15p region D15Z1 is recognized as a polymorphism in several human populations. We used high-stringency Fluorescence In...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5252: Fusion Transcripts of Adjacent Genes: New Insights into the World of Human Complex Transcripts in Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20215252 Authors: Vincenza Barresi Ilaria Cosentini Chiara Scuderi Salvatore Napoli Virginia Di Bella Giorgia Spampinato Daniele Filippo Condorelli The awareness of genome complexity brought a radical approach to the study of transcriptome, opening eyes to single RNAs generated...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5255: Expression of Two α-Type Expansins from Ammopiptanthus nanus in Arabidopsis thaliana Enhance Tolerance to Cold and Drought Stresses International Journal of Molecular Sciences doi: 10.3390/ijms20215255 Authors: Yanping Liu Li Zhang Wenfang Hao Ling Zhang Yi Liu Longqing Chen Expansins, cell-wall loosening proteins, play an important role in plant growth and development and abiotic stress tolerance. Ammopiptanthus nanus (A. nanus) is an important...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5250: Coix Seed Extract Enhances the Anti-Pancreatic Cancer Efficacy of Gemcitabine through Regulating ABCB1- and ABCG2-Mediated Drug Efflux: A Bioluminescent Pharmacokinetic and Pharmacodynamic Study International Journal of Molecular Sciences doi: 10.3390/ijms20215250 Authors: Qian Xiong Feng Wu Zhang Chen Gu A deep insight into the function and kinetics of ATP-binding cassette (ABC) transporters may aid in the development of pharmaceutics...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5248: Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins International Journal of Molecular Sciences doi: 10.3390/ijms20215248 Authors: Mark Tingey Krishna C. Mudumbi Eric C. Schirmer Weidong Yang The nuclear envelope (NE) surrounds the nucleus with a double membrane in eukaryotic cells. The double membranes are embedded with proteins that are synthesized on the endoplasmic reticulum and...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5246: A Mechanistic Perspective on PEX1 and PEX6, Two AAA+ Proteins of the Peroxisomal Protein Import Machinery International Journal of Molecular Sciences doi: 10.3390/ijms20215246 Authors: Ana G. Pedrosa Tânia Francisco Maria J. Ferreira Tony A. Rodrigues Aurora Barros-Barbosa Jorge E. Azevedo In contrast to many protein translocases that use ATP or GTP hydrolysis as the driving force to transport proteins across biological membranes, the peroxisomal...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5247: Identification of Gain and Loss of Function Missense Variants in MRGPRX2’s Transmembrane and Intracellular Domains for Mast Cell Activation by Substance P International Journal of Molecular Sciences doi: 10.3390/ijms20215247 Authors: Chalatip Chompunud Na Ayudhya Saptarshi Roy Ibrahim Alkanfari Anirban Ganguly Hydar Ali The neuropeptide substance P (SP) contributes to neurogenic inflammation through the activation of human mast cells via Mas-related...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5249: Tea and Its Components Prevent Cancer: A Review of the Redox-Related Mechanism International Journal of Molecular Sciences doi: 10.3390/ijms20215249 Authors: Xiangbing Mao Xiangjun Xiao Daiwen Chen Bing Yu Jun He Cancer is a worldwide epidemic and represents a major threat to human health and survival. Reactive oxygen species (ROS) play a dual role in cancer cells, which includes both promoting and inhibiting carcinogenesis. Tea remains one of the...
Wed Oct 23, 2019 03:00
IJMS, Vol. 20, Pages 5245: Disulfide Engineered Lipase to Enhance the Catalytic Activity: A Structure-Based Approach on BTL2 International Journal of Molecular Sciences doi: 10.3390/ijms20215245 Authors: César A. Godoy Javier Klett Bruno Di Geronimo Juan A. Hermoso José M. Guisán César Carrasco-López Enhancement, control, and tuning of hydrolytic activity and specificity of lipases are major goals for the industry. Thermoalkaliphilic lipases from the I.5 family, with their...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1766: Factors Associated with Successful Response to Balloon Decompressive Adhesiolysis Neuroplasty in Patients with Chronic Lumbar Foraminal Stenosis Journal of Clinical Medicine doi: 10.3390/jcm8111766 Authors: Oh Kim Park Ji Shin Lee Park Shin Choi Epidural neuroplasty, often called percutaneous epidural adhesiolysis, is often performed in refractory patients with chronic lumbar radiculopathy or neurogenic claudication. Recent studies...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1765: Less Is More: Ulnar Lengthening Alone without Radial Corrective Osteotomy in Forearm Deformity Secondary to Hereditary Multiple Exostoses Journal of Clinical Medicine doi: 10.3390/jcm8111765 Authors: Po-Jen Hsu Kuan-Wen Wu Chia-Che Lee Ken N. Kuo Jia-Feng Chang Ting-Ming Wang Ulnar lengthening has gained popularity in treating forearm deformity due to hereditary multiple exostoses (HME). Whether a simultaneous radius angular correction is necessary...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1767: Texture Analysis of Multi-Shot Echo-planar Diffusion-Weighted Imaging in Head and Neck Squamous Cell Carcinoma: The Diagnostic Value for Nodal Metastasis Journal of Clinical Medicine doi: 10.3390/jcm8111767 Authors: Park Bae Choi Jung Jeong Kim Sunwoo Jung Kim Accurate assessment of nodal metastasis in head and neck squamous cell carcinoma (SCC) is important, and diffusion-weighted imaging (DWI) has emerged as a potential technique...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1762: High Expression of TTYH3 is Related to Poor Clinical Outcomes in Human Gastric Cancer Journal of Clinical Medicine doi: 10.3390/jcm8111762 Authors: Saha Biswas Gil Cho Ion channels play important roles in regulating various cellular processes and malignant transformation. Expressions of some chloride channels have been suggested to be associated with patient survival in gastric cancer (GC). However, little is known about the expression and function...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1760: Comparison of Orthognathic Surgery Outcomes Between Patients With and Without Underlying High-Risk Conditions: A Multidisciplinary Team-Based Approach and Practical Guidelines Journal of Clinical Medicine doi: 10.3390/jcm8111760 Authors: Chou Denadai Chen Pai Hsu Chang Pascasio Lin Chen Lo Orthognathic surgery (OGS) has been successfully adopted for managing a wide spectrum of skeletofacial deformities, but patients with underlying...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1763: Regulation of c-Jun NH2-Terminal Kinase for Islet Transplantation Journal of Clinical Medicine doi: 10.3390/jcm8111763 Authors: Noguchi Islet transplantation has been demonstrated to provide superior glycemic control with reduced glucose lability and hypoglycemic events compared with standard insulin therapy. However, the insulin independence rate after islet transplantation from one donor pancreas has remained low. The low frequency of islet grafting is dependent...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1761: Pilates Method Improves Cardiorespiratory Fitness: A Systematic Review and Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm8111761 Authors: Fernández-Rodríguez Álvarez-Bueno Ferri-Morales Torres-Costoso Cavero-Redondo Martínez-Vizcaíno Cardiorespiratory fitness has been postulated as an independent predictor of several chronic diseases. We aimed to estimate the effect of Pilates on improving cardiorespiratory fitness and to explore...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1764: IL-1β and Statin Treatment in Patients with Myocardial Infarction and Diabetic Cardiomyopathy Journal of Clinical Medicine doi: 10.3390/jcm8111764 Authors: Liberale Carbone Camici Montecucco Statins are effective lipid-lowering drugs with a good safety profile that have become, over the years, the first-line therapy for patients with dyslipidemia and a real cornerstone of cardiovascular (CV) preventive therapy. Thanks to both cholesterol-related...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1758: The Factors Predicting Concordant Epidermal Growth Factor Receptor (EGFR) Mutation Detected in Liquid/Tissue Biopsy and the Related Clinical Outcomes in Patients of Advanced Lung Adenocarcinoma with EGFR Mutations Journal of Clinical Medicine doi: 10.3390/jcm8111758 Authors: Chia-Yu Kuo Mei-Hsuan Lee Ming-Ju Tsai Chih-Jen Yang Jen-Yu Hung Inn-Wen Chong Liquid biopsy to identify epidermal growth factor receptor (EGFR) gene mutations from circulating...
Wed Oct 23, 2019 03:00
JCM, Vol. 8, Pages 1759: Buffering Capacity in Sepsis: A Prospective Cohort Study in Critically Ill Patients Journal of Clinical Medicine doi: 10.3390/jcm8111759 Authors: Ioannis Vasileiadis Maria Kompoti Nikoletta Rovina Elli-Sophia Tripodaki Christos Filis Emmanouil Alevrakis Anna Kyriakoudi Magdalini Kyriakopoulou Nikolaos Koulouris Antonia Koutsoukou Background: The concept of buffering generally refers to the ability of a system/organism to withstand attempted...
Wed Oct 23, 2019 03:00
JoF, Vol. 5, Pages 101: Ongoing Challenges with Healthcare-Associated Candida auris Outbreaks in Oman Journal of Fungi doi: 10.3390/jof5040101 Authors: Al Maani Paul Al-Rashdi Wahaibi Al-Jardani Al Abri AlBalushi Abri Al Reesi Al Maqbali Al Kasaby de Groot Meis Al-Hatmi Candida auris has emerged in the past decade as a multi-drug resistant public health threat causing health care outbreaks. Here we report epidemiological, clinical,...
Wed Oct 23, 2019 03:00
Life, Vol. 9, Pages 80: Chemical Ecosystem Selection on Mineral Surfaces Reveals Long-Term Dynamics Consistent with the Spontaneous Emergence of Mutual Catalysis Life doi: 10.3390/life9040080 Authors: Vincent Berg Krismer Saghafi Cosby Sankari Vetsigian II Baum How did chemicals first become organized into systems capable of self-propagation and adaptive evolution? One possibility is that the first evolvers were chemical ecosystems localized on mineral...
Wed Oct 23, 2019 03:00
Membranes, Vol. 9, Pages 136: The Multilevel Structure of Sulfonated Syndiotactic-Polystyrene Model Polyelectrolyte Membranes Resolved by Extended Q-Range Contrast Variation SANS Membranes doi: 10.3390/membranes9110136 Authors: Maria-Maddalena Schiavone Hiroki Iwase Shin-ichi Takata Aurel Radulescu Membranes based on sulfonated synditoactic polystyrene (s-sPS) were thoroughly characterized by contrast variation small-angle neutron scattering (SANS) over a wide Q-range in dry...
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Metabolites, Vol. 9, Pages 245: Using Cerebral Metabolites to Guide Precision Medicine for Subarachnoid Hemorrhage: Lactate and Pyruvate Metabolites doi: 10.3390/metabo9110245 Authors: Kaneez Zahra Neethu Gopal William D. Freeman Marion T. Turnbull Subarachnoid hemorrhage (SAH) is one of the deadliest types of strokes with high rates of morbidity and permanent injury. Fluctuations in the levels of cerebral metabolites following SAH can be indicators of brain injury severity....
Wed Oct 23, 2019 03:00
Metabolites, Vol. 9, Pages 243: NMR-Metabolomics Shows That BolA Is an Important Modulator of Salmonella Typhimurium Metabolic Processes under Virulence Conditions Metabolites doi: 10.3390/metabo9110243 Authors: Graça-Lopes Graça Barahona Moreira Arraiano Gonçalves BolA is a ubiquitous global transcription factor. Despite its clear role in the induction of important stress-resistant physiological changes and its recent implication in the virulence of Salmonella,...
Wed Oct 23, 2019 03:00
Metabolites, Vol. 9, Pages 244: Neuroprotective Effect of Cyperi rhizome against Corticosterone-Induced PC12 Cell Injury via Suppression of Ca2+ Overloading Metabolites doi: 10.3390/metabo9110244 Authors: Jia Liu Yu Shang Zhang Ma Zhang Zou Cyperi Rhizoma (CR) is a well-known functional food and traditional herbal medicine in Asian countries for the treatment of menstrual or emotional disturbances in women. Recent studies have shown the pharmacological effects...
Wed Oct 23, 2019 03:00
Microorganisms, Vol. 7, Pages 482: Characteristics of Carbapenem-Resistant and Colistin-Resistant Escherichia coli Co-Producing NDM-1 and MCR-1 from Pig Farms in China Microorganisms doi: 10.3390/microorganisms7110482 Authors: Peng Li Hu Li Lv Lei Wu Chen Wang The emergence of carbapenem-resistant and colistin-resistant Enterobacteriaceae represents a great risk for public health. In this study, the phenotypical and genetic characteristics of eight carbapenem-resistant...
Wed Oct 23, 2019 03:00
Microorganisms, Vol. 7, Pages 483: Consolidated Bioprocess for Bioethanol Production from Raw Flour of Brosimum alicastrum Seeds Using the Native Strain of Trametes hirsuta Bm-2 Microorganisms doi: 10.3390/microorganisms7110483 Authors: Olguin-Maciel Larqué-Saavedra Lappe-Oliveras Barahona-Pérez Alzate-Gaviria Chablé-Villacis Domínguez-Maldonado Pacheco-Catalán Ruíz Tapia-Tussell Consolidated bioprocessing (CBP), which integrates biological pretreatment,...
Wed Oct 23, 2019 03:00
Microorganisms, Vol. 7, Pages 481: Bacterial and Fungal Endophytes: Tiny Giants with Immense Beneficial Potential for Plant Growth and Sustainable Agricultural Productivity Microorganisms doi: 10.3390/microorganisms7110481 Authors: Omomowo Babalola The conventional means of achieving enhanced agricultural productivity are not ecologically balanced and sustainable. The excessive use of synthetic agrochemicals, declining soil nutrients, and water-use issues, amongst others, are threats...
Wed Oct 23, 2019 03:00
Microorganisms, Vol. 7, Pages 480: Introducing Murine Microbiome Database (MMDB): A Curated Database with Taxonomic Profiling of the Healthy Mouse Gastrointestinal Microbiome Microorganisms doi: 10.3390/microorganisms7110480 Authors: Yang Park Park Baek Chun The gut microbiota modulates overall metabolism, the immune system and brain development of the host. The majority of mammalian gut microbiota consists of bacteria. Among various model animals, the mouse has been...
Wed Oct 23, 2019 03:00
Microorganisms, Vol. 7, Pages 484: Xylitol Production: Identification and Comparison of New Producing Yeasts Microorganisms doi: 10.3390/microorganisms7110484 Authors: Carneiro de Paula e Silva Almeida Xylitol is a sugar alcohol with five carbons that can be used in the pharmaceutical and food industries. It is industrially produced by chemical route; however, a more economical and environmentally friendly production process is of interest. In this context, this study aimed...
Wed Oct 23, 2019 03:00
Microorganisms, Vol. 7, Pages 479: Characterization and Transcriptional Regulation of n-Alkane Hydroxylase Gene Cluster of Rhodococcus jostii RHA1 Microorganisms doi: 10.3390/microorganisms7110479 Authors: Gibu Kasai Ikawa Akiyama Fukuda Gram-positive actinomycete Rhodococcus jostii RHA1 is able to grow on C10 to C19 n-alkanes as a sole source of carbon and energy. To clarify, the n-alkane utilization pathway—a cluster of 5 genes (alkBrubA1A2BalkU) which appeared...
Wed Oct 23, 2019 03:00
Microorganisms, Vol. 7, Pages 478: Characterizing the Potential of the Non-Conventional Yeast Saccharomycodes ludwigii UTAD17 in Winemaking Microorganisms doi: 10.3390/microorganisms7110478 Authors: Esteves Barbosa Vasconcelos Tavares Mendes-Faia Mira Mendes-Ferreira Non-Saccharomyces yeasts have received increased attention by researchers and winemakers, due to their particular contributions to the characteristics of wine. In this group, Saccharomycodes ludwigii...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3829: Inhibitory Effect of Oat Bran Ethanol Extract on Survival and Gemcitabine Resistance of Pancreatic Cancer Cells Molecules doi: 10.3390/molecules24213829 Authors: Myoungjae Kim Jeong-Geon Mun Hyun Jin Lee So-Ri Son Mi-Ja Lee Ji-Ye Kee Pancreatic cancer (PC) is one of the most aggressive malignancies in the world. Gemcitabine (Gem), a nucleoside pyrimidine analogue, is a first-line chemotherapeutic drug for PC, but the tumor response rate...
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Molecules, Vol. 24, Pages 3828: Effect of Different Amino Acids and Heating Conditions on the Formation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and Its Kinetics Formation Using Chemical Model System Molecules doi: 10.3390/molecules24213828 Authors: Ainaatul Asmaa Ishak Jinap Selamat Rabiha Sulaiman Rashidah Sukor Emilia Abdulmalek Nuzul Noorahya Jambari The formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) was investigated using a kinetic...
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Molecules, Vol. 24, Pages 3826: Various Patterns of Composition and Accumulation of Steroids and Triterpenoids in Cuticular Waxes from Screened Ericaceae and Caprifoliaceae Berries during Fruit Development Molecules doi: 10.3390/molecules24213826 Authors: Dashbaldan Becker Pączkowski Szakiel Cuticular waxes are primarily composed of two classes of lipids: compounds derived from very-long-chain fatty acids and isoprenoids, particularly triterpenoids and steroids. Isoprenoids...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3827: Influence of Potato Crisps Processing Parameters on Acrylamide Formation and Bioaccesibility Molecules doi: 10.3390/molecules24213827 Authors: Martinez Rodriguez Mondragon Lorenzo Santos A fractional factorial design was used to evaluate the effects of temperature, frying time, blanching treatment and the thickness of potato slices on acrylamide content in crisps. The design was used on freshly harvested and four-month stored potatoes....
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3825: The Impact of Long-and Short-Term Strontium Treatment on Metabolites and Minerals in Glycine max Molecules doi: 10.3390/molecules24213825 Authors: Hanaka Dresler Wójciak-Kosior Strzemski Kováčik Latalski Zawiślak Sowa The impact of long-term exposure to Sr2+ (LTE, four doses, 43.5 mg Sr2+ per pot, with a total of 174 mg Sr2+ per pot during the entire period of cultivation) and short-term exposure to Sr2+ (STE, one dose, 870...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3824: Enhanced Killing of Candida krusei by Polymorphonuclear Leucocytes in the Presence of Subinhibitory Concentrations of Melaleuca alternifolia and “Mentha of Pancalieri” Essential Oils Molecules doi: 10.3390/molecules24213824 Authors: Vivian Tullio Janira Roana Daniela Scalas Narcisa Mandras The aim of this study was to evaluate the influence of tea tree oil (TTO) and “Mentha of Pancalieri” essential oil (MPP) on intracellular...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3823: β-Amino- and Alkoxy-Substituted Disilanides Molecules doi: 10.3390/molecules24213823 Authors: Istvan Balatoni Johann Hlina Rainer Zitz Alexander Pöcheim Judith Baumgartner Christoph Marschner Our recent study on formal halide adducts of disilenes led to the investigation of the synthesis and properties of β-fluoro- and chlorodisilanides. The reaction of the functionalized neopentasilanes (Me3Si)3SiSiPh2NEt2 and (Me3Si)3SiSiMe2OMe...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3821: Novel Thiazolidin-4-ones as Potential Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase Molecules doi: 10.3390/molecules24213821 Authors: Petrou Eleftheriou Geronikaki Akrivou Vizirianakis Background: HIV is the causative agent of Acquired Immunodeficiency Syndrome (AIDS), an infectious disease with increasing incidence worldwide. Non-nucleoside reverse transcriptase inhibitors (NNRTIs) play an important role in the treatment of...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3820: Design, Synthesis and In Vitro Mechanistic Investigation of Novel Hexacyclic Cage-Like Hybrid Heterocycles Molecules doi: 10.3390/molecules24213820 Authors: Raju Almansour Natarajan Mohammad Novel hexacyclic cage-like hybrid heterocycles have been synthesized in excellent yields employing a relatively less explored non-stabilized azomethine ylides derived from acenaphthenequinone and tyrosine with functionalized dipolarophiles using [3 +...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3819: Synthesis of Novel Triazinoindole-Based Thiourea Hybrid: A Study on α-Glucosidase Inhibitors and Their Molecular Docking Molecules doi: 10.3390/molecules24213819 Authors: Taha Alshamrani Rahim Hayat Ullah Zaman Imran Khan Naz A new class of triazinoindole-bearing thiosemicarbazides (1–25) was synthesized and evaluated for α-glucosidase inhibitory potential. All synthesized analogs exhibited excellent...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3822: Insights into Heterologous Biosynthesis of Arteannuin B and Artemisinin in Physcomitrella patens Molecules doi: 10.3390/molecules24213822 Authors: Ikram Kashkooli Peramuna Krol Bouwmeester Simonsen : Metabolic engineering is an integrated bioengineering approach, which has made considerable progress in producing terpenoids in plants and fermentable hosts. Here, the full biosynthetic pathway of artemisinin, originating from Artemisia...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3817: Analysis of Pollution of Phthalates in Pork and Chicken in Taiwan Using Liquid Chromatography–Tandem Mass Spectrometry and Assessment of Health Risk Molecules doi: 10.3390/molecules24213817 Authors: Ming-Yang Tsai Chang-Hsun Ho Hong-You Chang Wei-Cheng Yang Chuen-Fu Lin Chien-Teng Lin Yi-Jing Xue Jyh-Mirn Lai Jiann-Hsiung Wang Geng-Ruei Chang Phthalates are widely used plasticizers that can cause endocrine disruption, mutagenicity,...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3818: X-ray Photospectroscopy and Electronic Studies of Reactor Parameters on Photocatalytic Hydrogenation of Carbon Dioxide by Defect-Laden Indium Oxide Hydroxide Nanorods Molecules doi: 10.3390/molecules24213818 Authors: Joel Y. Y. Loh Nazir P. Kherani In the study reported herein, glovebox-protected X-ray photoelectron spectroscopy (XPS) and in situ Hall charge carrier measurements provide new insights into the surface physical chemistry of gaseous H2,...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3816: Research Advances of Purple Sweet Potato Anthocyanins: Extraction, Identification, Stability, Bioactivity, Application, and Biotransformation Molecules doi: 10.3390/molecules24213816 Authors: Aoran Li Ruoshi Xiao Sijia He Xiaoyu An Yi He Chengtao Wang Sheng Yin Bin Wang Xuewei Shi Jingren He Purple sweet potato anthocyanins are kinds of natural anthocyanin red pigments extracted from the root or stem of purple sweet potato. They...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3814: Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. Molecules doi: 10.3390/molecules24213814 Authors: Sheng Wu Alexander E. Wilson Lijing Chang Li Tian Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored. In this work,...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3815: Nature-Inspired Polymerization of Quercetin to Produce Antioxidant Nanoparticles with Controlled Size and Skin Tone-Matching Colors Molecules doi: 10.3390/molecules24213815 Authors: Suhair Sunoqrot Eveen Al-Shalabi Lina Hasan Ibrahim Hiba Zalloum Plant polyphenols have received considerable attention in recent years due to their ability to undergo oxidation-triggered self-polymerization, forming biocompatible versatile coatings and templated nanoparticles...
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3813: The Manufacturing Process of Kiwifruit Fruit Powder with High Dietary Fiber and Its Laxative Effect Molecules doi: 10.3390/molecules24213813 Authors: Ziqi Zhuang Min Chen Jihan Niu Na Qu Bing Ji Xiang Duan Zhande Liu Xuebo Liu Yutang Wang Beita Zhao Kiwifruit is rich in vitamins, minerals, dietary fiber and other functional components, and it has long been used as a functional food to treat intestinal ailments such as constipation....
Wed Oct 23, 2019 03:00
Molecules, Vol. 24, Pages 3812: Nucleophilic Arylation of Halopurines Facilitated by Brønsted Acid in Fluoroalcohol Molecules doi: 10.3390/molecules24213812 Authors: Naoko Takenaga Toshitaka Shoji Takayuki Menjo Akiko Hirai Shohei Ueda Kotaro Kikushima Tomonori Hanasaki Toshifumi Dohi Various aryl-substituted purine derivatives were synthesized through the direct arylation of halopurines with aromatic compounds, facilitated by the combination of triflic acid and...
Wed Oct 23, 2019 03:00
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