Related ArticlesHigh lncRNA MEG3 expression is associated with high mortality rates in patients with sepsis and increased lipopolysaccharide-induced renal epithelial cell and cardiomyocyte apoptosis. Exp Ther Med. 2019 Nov;18(5):3943-3947 Authors: Chen K, Shi X, Jin Y, Wang F, Shen Q, Xu W Abstract Long non-coding RNA (lncRNA) maternally expressed 3 (MEG3) has been reported to be a key component in cancer biology. Preliminary microarray data from a previous...
Thu Oct 24, 2019 14:58
Related ArticlesMechanism and role of nitric oxide signaling in periodontitis. Exp Ther Med. 2019 Nov;18(5):3929-3935 Authors: Wang Y, Huang X, He F Abstract The present study investigated the role of the nitric oxide (NO) signaling pathway in the progression of periodontal disease, and explored the related genetic mechanisms. An experimental model of periodontitis was established in Sprague-Dawley rats, then they were divided into normal control, and...
Thu Oct 24, 2019 14:58
Related ArticlesHomocysteine inhibits the viability and migration ability of human umbilical vein endothelial cells by downregulating the expression of vascular endothelial growth factor. Exp Ther Med. 2019 Nov;18(5):3913-3919 Authors: Yu J, Zhang LL, Wu XP, Zhao R, Meng ZX, Wang K, Wang B, Wang H, Shi ZL, Li GX Abstract The current study aimed to explore the effect of homocysteine (Hcy) on the viability and migration ability of human umbilical vein...
Thu Oct 24, 2019 14:58
Related ArticlesOutcome prediction for patients with anterior circulation acute ischemic stroke following endovascular treatment: A single-center study. Exp Ther Med. 2019 Nov;18(5):3869-3876 Authors: Wu X, Liu G, Zhou W, Ou A, Liu X, Wang Y, Zhou S, Luo W, Liu B Abstract Previous studies have identified various factors associated with the outcomes of acute ischemic stroke (AIS) but considered only 1 or 2 predictive factors. The present study aimed to...
Thu Oct 24, 2019 14:58
Related ArticlesIntegrated bioinformatics analysis reveals role of the LINC01093/miR-96-5p/ZFAND5/NF-κB signaling axis in hepatocellular carcinoma. Exp Ther Med. 2019 Nov;18(5):3853-3860 Authors: Zheng Y, Yu K, Huang C, Liu L, Zhao H, Huo M, Zhang J Abstract Hepatocellular carcinoma (HCC) is a significant health burden worldwide and its pathogenesis remains to be fully elucidated. One of the means by which long non-coding (lnc)RNAs regulate gene expression...
Thu Oct 24, 2019 14:58
Related ArticlesAstragaloside IV regulates NF-κB-mediated cellular senescence and apoptosis of hepatic stellate cells to suppress PDGF-BB-induced activation. Exp Ther Med. 2019 Nov;18(5):3741-3750 Authors: Chen Z, Yao L, Liu Y, Pan Z, Peng S, Wan G, Cheng J, Wang J, Cao W Abstract Activated hepatic stellate cells (HSCs) are the principal effectors during hepatic fibrosis, which is characterized by the accumulation of extracellular matrix. Therefore,...
Thu Oct 24, 2019 14:58
Related ArticlesOral sarcomatoid squamous cell carcinoma: a retrospective study based on 14 cases. Histol Histopathol. 2019 Oct 23;:18176 Authors: Liu J, Xiao M, Wang Y Abstract The treatment outcomes for oral sarcomatoid squamous cell carcinoma (OSSCC) are far from satisfactory in our hospital. The aim of this study was to retrospectively summarize the OSSCC cases admitted to our department. From 2003 to 2017, 14 patients were hospitalized and diagnosed...
Thu Oct 24, 2019 14:37
Related Articles[Disfiguring neurinoma of the nose tip and the columella-rhinosurgical aspects]. HNO. 2019 Oct 22;: Authors: Maier H, Lorenz KJ, Woenkhaus C, Mühlmeier G Abstract Neurinomas in the nose and the nasal sinuses are rare. In the present work, we present an exceedingly rare case of a disfiguring neurinoma involving the nasal columella. Treatment of choice is complete resection of the tumor. For an optimal view for tumor resection and esthetic...
Thu Oct 24, 2019 14:26
Related ArticlesClinical and biological significance of EZH2 expression in endometrial cancer. Cancer Biol Ther. 2019 Oct 22;:1-10 Authors: Roh JW, Choi JE, Han HD, Hu W, Matsuo K, Nishimura M, Lee JS, Kwon SY, Cho CH, Kim J, Coleman RL, Lopez-Bernstein G, Sood AK Abstract The objective of this study was to examine the clinical significance of EZH2 expression and the therapeutic efficacy of its silencing in endometrial cancer. EZH2 expression in clinical...
Thu Oct 24, 2019 14:49
Related ArticlesLarge outbreak of tularaemia, central Sweden, July to September 2019. Euro Surveill. 2019 Oct;24(42): Authors: Dryselius R, Hjertqvist M, Mäkitalo S, Lindblom A, Lilja T, Eklöf D, Lindström A Abstract On 31 of July 2019, the Public Health Agency of Sweden was alerted about an increasing number of tularaemia cases in Gävleborg, a county in central Sweden. The number of cases increased thereafter peaking at about 150 reports of illnesses...
Thu Oct 24, 2019 13:57
Related ArticlesThe 'Finnish new variant of Chlamydia trachomatis' escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019. Euro Surveill. 2019 Oct;24(42): Authors: Johansen TB, Kløvstad H, Rykkvin R, Herrfurth-Erichsen EB, Sorthe J, Njølstad G, Ebbesen MH, Nygaard RM, Sandmoen EK, Thilesen C, Onken A, Liljedal I, Hadad R, Unemo M Abstract The 'Finnish new variant of Chlamydia trachomatis' (FI-nvCT), escaping detection...
Thu Oct 24, 2019 13:57
Related ArticlesInternational travel as source of a hospital outbreak with an unusual meticillin-resistant Staphylococcus aureus clonal complex 398, Denmark, 2016. Euro Surveill. 2019 Oct;24(42): Authors: Møller JK, Larsen AR, Østergaard C, Møller CH, Kristensen MA, Larsen J Abstract In May 2016, an unusual outbreak with the Panton-Valentine leukocidin-positive human variant of meticillin-resistant Staphylococcus aureus (MRSA) clonal complex 398 occurred...
Thu Oct 24, 2019 13:57
Related ArticlesSpatial variability in the reproduction number of Ebola virus disease, Democratic Republic of the Congo, January-September 2019. Euro Surveill. 2019 Oct;24(42): Authors: Mizumoto K, Tariq A, Roosa K, Kong J, Yan P, Chowell G Abstract The ongoing Ebola virus disease epidemic (August 2018─October 2019) in the Democratic Republic of the Congo, has been exacerbated by deliberate attacks on healthcare workers despite vaccination efforts. Using...
Thu Oct 24, 2019 13:57
Related ArticlesBurden of varicella complications in secondary care, England, 2004 to 2017. Euro Surveill. 2019 Oct;24(42): Authors: Bernal JL, Hobbelen P, Amirthalingam G Abstract BackgroundStrategies to control varicella vary across Europe. Evidence from established programmes has prompted the United Kingdom to re-evaluate the need for universal vaccination. The burden of complicated varicella is a key parameter in the cost-effectiveness analysis.AimOur...
Thu Oct 24, 2019 13:57
Related ArticlesCurrent trends and 30-day surgical outcomes for thyroglossal duct cyst excision in children. Int J Pediatr Otorhinolaryngol. 2019 Oct 15;128:109725 Authors: Cheng J, Lerebours R, Lee HJ Abstract OBJECTIVE: Identify current trends, adverse events, and clinical predictors in children treated with thyroglossal duct cyst surgery. METHODS: Cross-sectional analysis using American College of Surgeons (ACS) National Surgical Quality...
Thu Oct 24, 2019 15:14
Related ArticlesA multidisciplinary, video-based, curriculum for management of the intubated and surgical airway patient for a pediatric hospital in El Salvador. Int J Pediatr Otorhinolaryngol. 2019 Oct 15;128:109732 Authors: Ghersin ZJ, Yager P, Cummings BM, Hersh M C, Cayer M, Callans KM, Zablah EJ, Gallagher T, Abrego S, Bonilla J, Vela OS, Guzman L, Aguilar A, Hartnick CJ Abstract OBJECTIVE: Primary objective is to determine the rate of intubation...
Thu Oct 24, 2019 15:14
Related ArticlesHyperparameter-tuned prediction of somatic symptom disorder using functional near Infrared spectroscopy based dynamic functional connectivity. J Neural Eng. 2019 Oct 23;: Authors: Eken A, Çolak B, Bal NB, Kuşman A, Kızılpınar SÇ, Sayar Akaslan D, Baskak B Abstract OBJECTIVE: Somatic Symptom Disorder (SSD) is a reflection of medically unexplained physical symptoms that lead to distress and impairment in social and occupational functioning....
Thu Oct 24, 2019 14:29
Related ArticlesA multichannel magnetic stimulation system using submillimeter-sized coils: system development and experimental application to rodent brain in vivo. J Neural Eng. 2019 Oct 23;16(6):066014 Authors: Minusa S, Muramatsu S, Osanai H, Tateno T Abstract OBJECTIVE: Single coil-based systems for magnetic stimulation are widely used for neurostimulation in neuroscience research and clinical treatment of neurological diseases. However, parallelization...
Thu Oct 24, 2019 14:29
Related ArticlesReconstruction of dorsal and palmar defects of hand with anterolateral thigh flaps from one donor site. J Plast Reconstr Aesthet Surg. 2019 Sep 07;: Authors: Zhang G, Su H, Ju J, Li X, Fu Y, Hou R Abstract The anterolateral thigh (ALT) flap is becoming the flap of choice for reconstruction of soft tissue defects with primary donor site closure. The purpose of this report was to review the reconstruction of dorsal and palmar defects of...
Thu Oct 24, 2019 14:45
Related ArticlesClinicopathological features of malignant melanoma of the skin among patients seen at Kenyatta National Hospital. J Plast Reconstr Aesthet Surg. 2019 Oct 11;: Authors: Wanjiru FK, Nang'ole FW, Kahoro LN, Zuriel DM PMID: 31640945 [PubMed - as supplied by publisher]
Thu Oct 24, 2019 14:45
Related ArticlesLong-term outcomes of triple semicircular canal plugging for the treatment of intractable Meniere's disease: a single center experience of 361 cases. J Vestib Res. 2019 Oct 14;: Authors: Zhang D, Lv Y, Han Y, Li Y, Li X, Wang J, Song Y, Kong L, Jian H, Fan Z, Wang H Abstract INTRODUCTION: Meniere's disease is a common chronic inner ear disease. Because the definitive pathogenesis is still unknown, there is currently no cure for this disorder....
Thu Oct 24, 2019 13:00
Related ArticlesLaryngeal distribution of adult-onset recurrent respiratory papillomatosis: A longitudinal study. Laryngoscope. 2019 09;129(9):1993-1997 Authors: Hu L, Benedict PA, Garber D, Wang B, Amin MR, Branski RC Abstract OBJECTIVES/HYPOTHESIS: To describe recurrence patterns in patients with recurrent respiratory papillomatosis (RRP) following surgical intervention. STUDY DESIGN: Single-center, retrospective, longitudinal case series....
Thu Oct 24, 2019 13:13
Related ArticlesAssociation between laryngopharyngeal reflux and benign vocal folds lesions: A systematic review. Laryngoscope. 2019 09;129(9):E329-E341 Authors: Lechien JR, Saussez S, Nacci A, Barillari MR, Rodriguez A, Le Bon SD, Crevier-Buchman L, Harmegnies B, Finck C, Akst LM Abstract OBJECTIVES: To investigate the role of laryngopharyngeal reflux (LPR) in the development of benign lesions of the vocal folds (BLVF). METHODS: PubMed, Cochrane...
Thu Oct 24, 2019 13:13
Related ArticlesFactors associated with epiglottic petiole prolapse repositioning success. Laryngoscope. 2019 09;129(9):1984-1988 Authors: Bergeron M, de Alarcon A, Hart CK, Rutter MJ Abstract OBJECTIVE: Epiglottic petiole prolapse is an overlooked entity that could lead to supraglottic airway obstruction for patients with complex airway history. Classical symptoms include exercise intolerance, obstructive sleep apnea, and difficulty with decannulation....
Thu Oct 24, 2019 13:13
Related ArticlesSuture lateralisation plus arytenoid cartilage release for treating bilateral vocal fold immobility with mechanical fixation. Acta Otorhinolaryngol Ital. 2019 Feb;39(1):18-21 Authors: Su WF, Lan MC, Liu SC PMID: 29393926 [PubMed - indexed for MEDLINE]
Thu Oct 24, 2019 13:13
Related ArticlesSimple dural closure using a knotless barbed suture in endoscopic transsphenoidal surgery: preliminary experience. Acta Otolaryngol. 2019 Oct 23;:1-5 Authors: Cong Z, Wang H, Ma C Abstract Background: Several literatures reported that suturing dura was reliable in preventing cerebrospinal fluid (CSF) leak in transsphenoidal surgery. However, suturing and knotting is technically challenging and time consuming in the transsphenoidal approach....
Thu Oct 24, 2019 14:58
Related ArticlesAdvances and challenges in precision medicine in salivary gland cancer. Cancer Treat Rev. 2019 Oct 14;80:101906 Authors: Lassche G, van Boxtel W, Ligtenberg MJL, van Engen-van Grunsven ACH, van Herpen CML Abstract Salivary gland cancer (SGC) is a rare malignancy consisting of 22 subtypes with different genetic, histological and clinical characteristics. This rarity and heterogeneity makes systemic treatment of recurrent or metastatic...
Thu Oct 24, 2019 14:28
Related ArticlesSpecific challenges in end-of-life care for patients with hematological malignancies. Curr Opin Support Palliat Care. 2019 Oct 21;: Authors: Gerlach C, Alt-Epping B, Oechsle K Abstract PURPOSE OF REVIEW: The disease-related burden of patients with hematological malignancies is comparable with patients suffering from solid tumors. Palliative care offers relief from suffering independent of type of disease and prognosis. The prevalence...
Thu Oct 24, 2019 14:28
Related ArticlesImpact of Increasing Wait Times on Overall Mortality of Chimeric Antigen Receptor T-Cell Therapy in Large B-Cell Lymphoma: A Discrete Event Simulation Model. JCO Clin Cancer Inform. 2019 Oct;3:1-9 Authors: Tully S, Feng Z, Grindrod K, McFarlane T, Chan KKW, Wong WWL Abstract PURPOSE: The development of chimeric antigen receptor (CAR) T cells has transformed oncology treatment, with the potential to cure certain cancers. Although shown...
Thu Oct 24, 2019 14:28
Related ArticlesMelanoma-Targeting Property of Y-90-Labeled Lactam-Cyclized α-Melanocyte-Stimulating Hormone Peptide. Cancer Biother Radiopharm. 2019 Oct 23;: Authors: Xu J, Yang J, Gonzalez R, Fisher DR, Miao Y Abstract Purpose: The purpose of this study was to evaluate melanoma-targeting property of 90Y-DOTA-GGNle-CycMSHhex to facilitate its potential therapeutic application. Materials and Methods: DOTA-GGNle-CycMSHhex was synthesized and readily labeled...
Thu Oct 24, 2019 14:28
Related ArticlesFactors Associated With Complete Remission After Rituximab Therapy for Pemphigus. JAMA Dermatol. 2019 Oct 23;: Authors: Kushner CJ, Wang S, Tovanabutra N, Tsai DE, Werth VP, Payne AS Abstract Importance: Rituximab has emerged as a front-line therapy for pemphigus, but prognostic factors for achieving complete remission off therapy (CROT) with oral systemic agents remain unknown. Objectives: To describe rates of CROT and relapse...
Thu Oct 24, 2019 14:28
Related ArticlesBIGART 2019 - adapting to the future. Acta Oncol. 2019 Oct;58(10):1323-1327 Authors: Overgaard J, Muren LP, Høyer M, Grau C PMID: 31642743 [PubMed - in process]
Thu Oct 24, 2019 14:28
Related ArticlesPopulation-based birth defects data in the United States, 2012-2016: A focus on abdominal wall defects. Birth Defects Res. 2019 Oct 23;: Authors: Stallings EB, Isenburg JL, Short TD, Heinke D, Kirby RS, Romitti PA, Canfield MA, O'Leary LA, Liberman RF, Forestieri NE, Nembhard WN, Sandidge T, Nestoridi E, Salemi JL, Nance AE, Duckett K, Ramirez GM, Shan X, Shi J, Lupo PJ Abstract BACKGROUND/OBJECTIVES: In this report, the National Birth...
Thu Oct 24, 2019 14:28
Related ArticlesExosomal miRNA-1231 derived from bone marrow mesenchymal stem cells inhibits the activity of pancreatic cancer. Cancer Med. 2019 Oct 23;: Authors: Shang S, Wang J, Chen S, Tian R, Zeng H, Wang L, Xia M, Zhu H, Zuo C Abstract Pancreatic cancer (PC) is a highly malignant tumor with increased morbidity and mortality, which is difficult to diagnose and cure in the clinic. Through secreting exosomes containing biological molecules, including...
Thu Oct 24, 2019 14:28
Related ArticlesCD4+ CADM1+ cell percentage predicts disease progression in HTLV-1 carriers and indolent adult T-cell leukemia/lymphoma. Cancer Sci. 2019 Oct 23;: Authors: Makiyama J, Kobayashi S, Watanabe E, Ishigaki T, Kawamata T, Nakashima M, Yamagishi M, Nakano K, Tojo A, Watanabe T, Uchimaru K Abstract We recently took advantage of the universal expression of cell adhesion molecule 1 (CADM1) by CD4+ cells infected with human T-cell leukemia virus...
Thu Oct 24, 2019 14:28
Related ArticlesOptimizing cancer care for hepatocellular carcinoma at a safety-net hospital: The value of a multidisciplinary disease management team. J Surg Oncol. 2019 Oct 22;: Authors: Duininck G, Lopez-Aguiar AG, Lee RM, Miller L, Dariushnia S, Wu C, Alese OB, Lin JY, Wedd J, Adams A, Maithel SK, Russell MC Abstract BACKGROUND: Hepatitis C (HCV) is the primary etiology of hepatocellular carcinoma (HCC) in the US multidisciplinary disease management...
Thu Oct 24, 2019 13:28
Related ArticlesFong's Score in the Era of Modern Perioperative Chemotherapy for Metastatic Colorectal Cancer: A Post Hoc Analysis of the GERCOR-MIROX Phase III Trial. Ann Surg Oncol. 2019 Oct 22;: Authors: Makhloufi S, Turpin A, El Amrani M, André T, Truant S, Bachet JB, Vernerey D, Hebbar M Abstract BACKGROUND: Despite improvement in colorectal liver metastasis (CLM) treatment, survival after liver surgery remains highly variable. Several clinicopathologic...
Thu Oct 24, 2019 13:28
Related ArticlesPrognostic Models for Predicting Overall Survival in Patients with Primary Gastric Cancer: A Systematic Review. Biomed Res Int. 2019;2019:5634598 Authors: Feng Q, May MT, Ingle S, Lu M, Yang Z, Tang J Abstract Background: This study was designed to review the methodology and reporting of gastric cancer prognostic models and identify potential problems in model development. Methods: This systematic review was conducted following...
Thu Oct 24, 2019 13:28
Related ArticlesInflammatory Biomarkers as Predictors of Response to Immunotherapy in Urological Tumors. J Oncol. 2019;2019:7317964 Authors: Schepisi G, Brighi N, Cursano MC, Gurioli G, Ravaglia G, Altavilla A, Burgio SL, Testoni S, Menna C, Farolfi A, Casadei C, Tonini G, Santini D, De Giorgi U Abstract Immunotherapy represents the new era of cancer treatment because of its promising results in various cancer types. In urological tumors, the use of...
Thu Oct 24, 2019 13:28
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