Related ArticlesIncidence and Outcomes of Acute Laryngeal Injury After Prolonged Mechanical Ventilation. Crit Care Med. 2019 Oct 17;: Authors: Shinn JR, Kimura KS, Campbell BR, Sun Lowery A, Wootten CT, Garrett CG, Francis DO, Hillel AT, Du L, Casey JD, Ely EW, Gelbard A Abstract OBJECTIVES: Upper airway injury is a recognized complication of prolonged endotracheal intubation, yet little attention has been paid to the consequences of laryngeal injury...
Related ArticlesOral Cancer: Integration of Studies for Diagnostic and Therapeutic Precision. Adv Dent Res. 2019 Nov;30(2):45-49 Authors: D'Silva NJ, Gutkind JS Abstract Head and neck cancers are among the 10 most common cancers in the world and include cancers of the oral cavity, hypopharynx, larynx, nasopharynx, and oropharynx. At least 90% of head and neck cancers are squamous cell carcinomas (SCCs). This summary discusses the integration of clinical...
Related ArticlesLarge Laryngeal Lipoma with Extra Laryngeal Component Mimics Mixed Form Laryngocele: A Case Report. Adv J Emerg Med. 2019;3(4):e45 Authors: Azandaryani AR, Eftekharian M, Taghipour M Abstract Introduction: Lipomas are the most common benign neoplasms, occurring in any part of the body where fat is present. Their occurrence in the head and neck is not common. Here, we report a large laryngeal lipoma with extra laryngeal component, mimicking...
Related ArticlesSphenoid sinus development in patients with acquired middle ear cholesteatoma. Auris Nasus Larynx. 2019 Oct 17;: Authors: Arai Y, Sano D, Takahashi M, Nishimura G, Sakamaki K, Sakuma N, Komatsu M, Oridate N Abstract OBJECTIVE: In this study, we examine the relationship between developmental insufficiency of mastoid air cells and abnormal morphology of the paranasal sinuses in patients with chronic otitis media (COM) and acquired middle...
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While pain relief is more commonly associated with total joint replacement patients than other surgical procedures it is not associated with an increased risk when pre‐surgical opioid use is taken into account. Primary care clinicians and surgeons should monitor the duration and dosage of pre‐surgery opioid use regardless of surgery procedure and conservative pre‐operative management of total joint replacement patients with opioids should be discouraged. Abstract Background Persistent opioid...
In September 2017, the old Royal Adelaide Hospital was closed and all patients and staff moved to the recently constructed new Royal Adelaide Hospital. Our 12‐week study of the Acute Surgical Unit at the Royal Adelaide Hospital examines the impact that this move had on key performance indicators of patient care. Our study also examined the compensatory measures implemented for the anticipated upheaval and details what lessons were learned by our unit in an effort to inform similar transition events...
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Related ArticlesCold Technique in Adult Tonsillectomy Reduces Waste and Cost. Ear Nose Throat J. 2019 Oct 20;:145561319882779 Authors: Meiklejohn DA, Chavarri VM Abstract OBJECTIVES: To quantify differences in waste and cost of disposable equipment between different tonsillectomy techniques. METHODS: Prospective study of waste attributable to disposable waste produced by tonsillectomy surgery. Disposable equipment required for tonsillectomy...
Related ArticlesVitamin D Levels in Children With Recurrent Aphthous Stomatitis. Ear Nose Throat J. 2019 Oct 20;:145561319882783 Authors: Nalbantoğlu B, Nalbantoğlu A Abstract BACKGROUND: Recurrent aphthous stomatitis is one of the most prevalent oral mucosa diseases and the etiology is unclear. As a potent anti-inflammatory and immunomodulating agent, vitamin D can significantly affect oral cavity homeostasis. However, to the best of our knowledge,...
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Publication date: December 2019Source: European Journal of Cancer, Volume 123Author(s): Martin D. Forster, Magnus T. Dillon, Judit Kocsis, Éva Remenár, Gabor Pajkos, Frederic Rolland, Jonathan Greenberg, Kevin J. HarringtonAbstractBackgroundThe fully human monoclonal antibody patritumab blocks HER3 activation, a resistance mechanism to cetuximab, induced by heregulin (HRG). A phase Ib study in recurrent and/or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) demonstrated tolerability...
Publication date: Available online 22 October 2019Source: European Journal of CancerAuthor(s): Karin Holmsten, Niels Viggo Jensen, Lene Sonne Mouritsen, Erika Jonsson, Camilla Mellnert, Mads Agerbæk, Cecilia Nilsson, Mette Moe, Andreas Carus, Elisabeth Öfverholm, Outi Lahdenperä, Yvonne Brandberg, Hemming Johansson, Mats Hellström, Hans von der Maase, Helle Pappot, Anders UllénAbstractBackgroundThe present study (VINGEM) is the first randomised trial comparing vinflunine/gemcitabine (VG) to standard...
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Abstract Pesticides are now chronically found in numerous ecosystems incurring widespread toxic effects on multiple organisms. For insects, the larvae are very exposed to pesticide pollution and the acute effect of insecticides on larvae has been characterised in a range of species. However, the carry‐on effects in adults of sublethal exposure occurring in larvae is not well characterised. Here, we use a collection of strains of Drosophila melanogaster differing in their larval resistance to a commonly...
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Abstract Background Dentine hypersensitivity can impact functional status and everyday activities such as eating and talking. This study aimed to assess changes in oral health-related quality of life measures in individuals with dentine hypersensitivity following long-term use (24 weeks) of a commercially available toothpaste marketed for dentine hypersensitivity relief. ...
Abstract Background Oxidative stress is involved in many diseases including diabetes and cancer. Numbers of studies have suggested its involvement in the pathogenesis of periodontal diseases. The aim of this study was to evaluate the levels of biochemical parameters and oxidative stress markers in plasma of healthy and chronic periodontitis patients. Methods ...
Abstract Background Traumatic dental injuries (TDIs) are highly prevalent during childhood and adolescence and have a significant effect on their oral health related quality of life (OHRQoL). Uncomplicated TDIs, dental trauma involving enamel, enamel and dentin and tooth discolorations, account for approximately two-thirds of all diagnosed TDIs in children and adolescents. Hence, it may be important to understand the impact of uncomplicated...
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Publication date: November 2019Source: Radiotherapy and Oncology, Volume 140Author(s):
Publication date: November 2019Source: Radiotherapy and Oncology, Volume 140Author(s):
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Combined Endoscopic and Microscopic Surgery for Perilabyrinthine Lesions: Feasibility and Technique.
Related ArticlesCombined Endoscopic and Microscopic Surgery for Perilabyrinthine Lesions: Feasibility and Technique. Otol Neurotol. 2019 Oct 18;: Authors: Wei X, Gao Z, Tian X, Zhao Y, Feng G Abstract OBJECTIVES: To determine the feasibility of endoscopic-assisted surgery for lesions involving the perilabyrinthine recesses, and develop and validate a technique for this kind of lesions that increases the possibility of preserving the labyrinth and cochlea....
Related ArticlesNF2-Related Intravestibular Schwannomas: Long-Term Outcomes of Cochlear Implantation. Otol Neurotol. 2019 Oct 18;: Authors: Jia H, Nguyen Y, Hochet B, Smail M, Mosnier I, Wu H, Sterkers O, Kalamarides M, Bernardeschi D Abstract OBJECTIVE: Intravestibular schwannomas (IVS) are uncommon tumors in Neurofibromatosis type 2 (NF2) and are mainly associated with multiple internal auditory meatus (IAM) and cerebellopontine angle (CPA) tumors....
Related ArticlesSupraclavicular Artery Island Flap in Head and Neck Reconstruction: A Case Series and Literature Review. Perm J. 2019;23: Authors: Wong S, Brennan M, Nishikawa S, Lim JH Abstract INTRODUCTION: Supraclavicular artery island flap (SCAIF) is emerging as an efficient and reliable flap for various complex head and neck defects after tumor extirpation. OBJECTIVE: To examine a series of cases using a SCAIF for head and reconstruction...
Related ArticlesRobotic surgery of the anterior skull base. Int Forum Allergy Rhinol. 2019 Oct 21;: Authors: Campbell RG Abstract BACKGROUND: Significant advances have been made in transoral robotic surgery (TORS), yet its application in anterior skull-base surgery has yet to be defined. This work explores the history of endoscopic sinus and anterior skull-base surgery, and its advantages and disadvantages. The development of robotic surgery is then...
Related ArticlesChronic Implantation of Multiple Flexible Polymer Electrode Arrays. J Vis Exp. 2019 Oct 04;(152): Authors: Chung JE, Joo HR, Smyth CN, Fan JL, Geaghan-Breiner C, Liang H, Liu DF, Roumis D, Chen S, Lee KY, Pebbles JA, Tooker AC, Tolosa VM, Frank LM Abstract Simultaneous recordings from large populations of individual neurons across distributed brain regions over months to years will enable new avenues of scientific and clinical development....
Related ArticlesRelease of the Lateral Pharyngeal Mucosa Using a Palatal Elevator. J Craniofac Surg. 2019 Oct 17;: Authors: Hwang K, Ma SH, Lee SI Abstract The aim of this paper is to present how to release the nasal mucosa from the hard palate and from the lateral pharyngeal wall using palatal elevator.After mucoperiosteal flap is raised, the nasal mucosa is detached with an instrument pushed laterally behind the palatine vessels to meet the medial...
Related ArticlesProspective Validation of Facial Nerve Monitoring to Prevent Nerve Damage During Robotic Drilling. Front Surg. 2019;6:58 Authors: Ansó J, Dür C, Apelt M, Venail F, Scheidegger O, Seidel K, Rohrbach H, Forterre F, Dettmer MS, Zlobec I, Weber K, Matulic M, Zoka-Assadi M, Huth M, Caversaccio M, Weber S Abstract Facial nerve damage has a detrimental effect on a patient's life, therefore safety mechanisms to ensure its preservation are essential...
Related ArticlesClinical Benefits of Combining Different Visualization Modalities in Neurosurgery. Front Surg. 2019;6:56 Authors: Schebesch KM, Rosengarth K, Brawanski A, Proescholdt M, Wendl C, Höhne J, Ott C, Lamecker H, Doenitz C Abstract The prevailing philosophy in oncologic neurosurgery, has shifted from maximally invasive resection to the preservation of neurologic function. The foundation of safe surgery is the multifaceted visualization of the...
Related ArticlesFailure Pressures of Dural Repairs in a Porcine Ex Vivo Model: Novel Use of Titanium Clips Versus Tissue Glue. Allergy Rhinol (Providence). 2019 Jan-Dec;10:2152656719879677 Authors: Chorath K, Krysinski M, Bunegin L, Majors J, Weitzel EK, McMains KC, Chen PG Abstract Objective: Endoscopic skull base surgery is advancing, and it is important to have reliable methods to repair the resulting defect. The objective of this study was to determine...
Related ArticlesAnatomo-radiological study supporting the use of ipsilateral nasoseptal flap for the transpterygoid management of temporo-sphenoidal meningoceles. A review of 21 cases. Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Oct 17;: Authors: Bartier S, Verillaud B, Guichard JP, Kania R, Camous D, Herman P Abstract OBJECTIVES: Surgical treatment of temporo-sphenoidal meningoceles involves the reduction of the meningocele, watertight closure and...
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Related ArticlesSilencing of Synaptotagmin 7 regulates osteosarcoma cell proliferation, apoptosis, and migration. Histol Histopathol. 2019 Oct 21;:18174 Authors: Wu Z, Sun Z, Huang R, Zang D, Wang C, Yan X, Yan W Abstract BACKGROUND: Synaptotagmin 7 (SYT7) is a component of the synaptotagmin family, which is essential in many physiological and pathological processes. In this study, we aimed to investigate the role of SYT7 in osteosarcoma. METHODS:...
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Publication date: Available online 21 October 2019Source: Gait & PostureAuthor(s): Farahnaz Fallahtafti, Carolin Curtze, Kaeli Samson, Jennifer M. YentesAbstractBackgroundA relationship exists between step width and energy expenditure, yet the contribution of dynamic stability to energy expenditure is not completely understood. Chronic obstructive pulmonary disease (COPD) patients’ energy expenditure is increased due to airway obstruction. Further, they have a higher prevalence of falls and balance...
Publication date: Available online 21 October 2019Source: Gait & PostureAuthor(s): Edward P. Washabaugh, Thomas E. Augenstein, Chandramouli KrishnanAbstractBackgroundTask-specific loading of the limbs—termed as functional resistance training—is commonly used in gait rehabilitation; however, the biomechanical and neuromuscular effects of various forms of functional resistance training have not been studied systematically. This information is crucial for correctly selecting the appropriate mode...
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Publication date: Available online 21 October 2019Source: Archives of Physical Medicine and RehabilitationAuthor(s): Kengo Kawanishi, Shintarou Kudo, Katsushi YokoiAbstractObjectivesTo investigate the association between gliding and lateral femoral pain (LFP) with trochanteric fracture (TF).DesignProspective, cohort study.SettingThe survey was conducted at approximately 3 weeks and 11 weeks postoperatively.ParticipantsPatients (N=23) with TF after surgery.InterventionsNot applicable.Main Outcome...
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Related ArticlesImproving Tracheostomy Care in Resource-Limited Settings. Ann Otol Rhinol Laryngol. 2019 Oct 21;:3489419882972 Authors: Sandler ML, Ayele N, Ncogoza I, Blanchette S, Munhall DS, Marques B, Nuss RC Abstract OBJECTIVES: Tracheostomy care in leading pediatric hospitals is both multidisciplinary and comprehensive, including generalized care protocols and thorough family training programs. This level of care is more difficult in resource-limited...
Related ArticlesIsolated Congenital Middle Ear Malformations: Comparison of Preoperative High-Resolution CT and Surgical Findings. Ann Otol Rhinol Laryngol. 2019 Oct 21;:3489419883659 Authors: Zhang N, Li Y, Ma X, Wang D, Li S, Yan F, Zhao S Abstract OBJECTIVES: To compare preoperative temporal bone high-resolution computed tomography (HRCT) readings to intraoperative findings during exploratory tympanotomy for suspected cases of isolated congenital...
Related ArticlesDetection of Pepsin in Oral Secretions of Infants with and without Laryngomalacia. Ann Otol Rhinol Laryngol. 2019 Oct 21;:3489419884332 Authors: Klimara MJ, Samuels TL, Johnston N, Chun RH, McCormick ME Abstract OBJECTIVES: Laryngomalacia is a common cause of stridor in infants and is associated with laryngopharyngeal reflux (LPR). Although pepsin in operative supraglottic lavage specimens is associated with severe laryngomalacia, detection...
Related ArticlesPreoperative Maxillary Sinus Imaging and the Outcome of Sinus Floor Augmentation and Dental Implants in Asymptomatic Patients. Ann Otol Rhinol Laryngol. 2019 Oct 21;:3489419883292 Authors: Ritter A, Rozendorn N, Avishai G, Rosenfeld E, Koren I, Soudry E Abstract OBJECTIVES: Preoperative maxillary sinus imaging findings have been suggested to be associated with complications and outcomes of sinus lift and dental implant procedures; nonetheless...
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Related ArticlesAtopic dermatitis epidemiology and unmet need in the United Kingdom. J Dermatolog Treat. 2019 Oct 21;:1-9 Authors: Cork MJ, Danby SG, Ogg GS Abstract Atopic dermatitis (AD), also known as atopic eczema, is a chronic inflammatory skin condition associated with a significant health-related and socioeconomic burden, and is characterized by intense itch, disruption of the skin barrier, and upregulation of type 2-mediated immune responses....
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