Annals of Neurology
- Antiepileptic drugs and suicide: the role of prior suicidal behavior and parental psychiatric disorderAbstract Objective To examine if prior suicidal behavior and familial predisposition to psychiatric disorders modify the association between antiepileptic drug use and completed suicide. Methods Using the Danish National Prescription Register, we identified all incident users of antiepileptic drugs aged 15 years or older in Denmark between July 1997 and December 2015. We carried out a nested case‐control study and defined exposure to an
- Submentalis REM Sleep Muscle Activity: A Potential Biomarker for SynucleinopathyABSTRACT Accurate antemortem diagnosis of Parkinsonism is primarily based on clinical evaluation with limited biomarkers. We evaluated the diagnostic utility of quantitative REM sleep without atonia analysis in the submentalis and anterior tibialis muscles in parkinsonian patients (53 synucleinopathy, 24 tauopathy). Receiver‐operating characteristic curves determined REM sleep without atonia cutoffs distinguishing synucleinopathies from tauopath
Clinical Neurology and Neurosurgery
- Application of Radiomics in Central Nervous System Diseases: a systematic literature reviewPublication date: Available online 16 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Yanghua Fan, Ming Feng, Renzhi WangAbstractCentral nervous system (CNS) diseases are associated with complexity and diversity; as a result, it is urgent to search for a simple approach for effectively improving the clinical decision-making ability and precise treatment currently. Radiomics can collect plenty of quantitative characteristics base
Latest Results for Child's Nervous System
Neuroradiology
- MR Imaging of the Extracranial Facial Nerve with the CISS Sequence [HEAD & NECK]BACKGROUND AND PURPOSE:MR imaging is not routinely used to image the extracranial facial nerve. The purpose of this study was to determine the extent to which this nerve can be visualized with a CISS sequence and to determine the feasibility of using that sequence for locating the nerve relative to tumor.MATERIALS AND METHODS:Thirty-two facial nerves in 16 healthy subjects and 4 facial nerves in 4 subjects with parotid gland tumors were imaged wi
- White Matter Injury and Structural Anomalies in Infants with Prenatal Opioid Exposue [PEDIATRICS]SUMMARY:Previous studies have not found structural injury or brain malformations in infants and children with prenatal opioid exposure. As part of an ongoing study evaluating neuroimaging in infants with prenatal opioid exposure, we reviewed structural brain MR imaging in 20 term infants with prenatal opioid exposure and 20 term controls at 4–8 weeks of age. We found that 8 of the 20 opioid-exposed infants had punctate white matter lesions or whi
- Incidental Brain MRI Findings in Children: A Systematic Review and Meta-Analysis [PEDIATRICS]BACKGROUND:The detection of incidental findings on children's brain MR imaging poses various practical issues because the life-long implications of such findings may be profound.PURPOSE:Our aim was to assess the prevalence and characteristics of incidental brain MR imaging findings in children.DATA SOURCES:Electronic databases (PubMed, EMBASE, and Cochrane) were searched for articles published between 1985 to July 2018, with the following search
- Hemodynamic Analysis of Postoperative Rupture of Unruptured Intracranial Aneurysms after Placement of Flow-Diverting Stents: A Matched Case-Control Study [INTERVENTIONAL]BACKGROUND AND PURPOSE:Postoperative rupture of intracranial aneurysm has been reported as a fatal complication after flow-diverter placement. We assessed several hemodynamic variables to explore risk factors in the postoperative rupture process.MATERIALS AND METHODS:We enrolled 10 patients with intracranial aneurysms, treated with flow diverters between September 2014 and December 2018, who experienced postoperative aneurysm rupture (postoperati
- Biometry of the Cerebellar Vermis and Brain Stem in Children: MR Imaging Reference Data from Measurements in 718 Children [PEDIATRICS]BACKGROUND AND PURPOSE:Objective and quantitative data to define cerebellar vermis and/or brain stem hypoplasia in children are lacking. Our aim was to provide MR imaging biometric references for the cerebellar vermis and brain stem from a large cohort of children with normal cerebellums.MATERIALS AND METHODS:The MR imaging data were retrospectively selected from our hospital data base from January 1, 2014, to December 31, 2017. All MR imaging ex
- Middle Cerebral Artery Plaque Hyperintensity on T2-Weighted Vessel Wall Imaging Is Associated with Ischemic Stroke [ADULT BRAIN]BACKGROUND AND PURPOSE:Vessel wall imaging can identify intracranial atherosclerotic plaque and give clues about its components. We aimed to investigate whether the plaque hyperintensity in the middle cerebral artery on T2-weighted vessel wall imaging is associated with ischemic stroke.MATERIALS AND METHODS:We retrospectively reviewed our institutional vessel wall MR imaging data base. Patients with an acute ischemic stroke within 7-day onset in
- Prolonged Microgravity Affects Human Brain Structure and Function [ADULT BRAIN]BACKGROUND AND PURPOSE:Widespread brain structural changes are seen following extended spaceflight missions. The purpose of this study was to investigate whether these structural changes are associated with alterations in motor or cognitive function.MATERIALS AND METHODS:Brain MR imaging scans of National Aeronautics and Space Administration astronauts were retrospectively analyzed to quantify pre- to postflight changes in brain structure. Local
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