Cancer-associated fibroblasts in the tumor microenvironment of tongue carcinoma is a heterogeneous cell population.Related ArticlesCancer-associated fibroblasts in the tumor microenvironment of tongue carcinoma is a heterogeneous cell population. Acta Histochem. 2019 Oct 08;:151446 Authors: Vered M, Shnaiderman-Shapiro A, Zlotogorski-Hurvitz A, Salo T, Yahalom R Abstract OBJECTIVES: To examine different immunophenotypes of cancer-associated fibroblasts (CAFs) in tongue squamous cell carcinoma (TSCC) and to investvestibular evoked
- Clinical significance of cervical and ocular vestibular evoked myogenic potentials in benign paroxysmal positional vertigo: a meta-analysis.Related ArticlesClinical significance of cervical and ocular vestibular evoked myogenic potentials in benign paroxysmal positional vertigo: a meta-analysis. Eur Arch Otorhinolaryngol. 2019 Oct 11;: Authors: Oya R, Imai T, Takenaka Y, Sato T, Oshima K, Ohta Y, Inohara H Abstract PURPOSE: As the pathological cause of benign paroxysmal positional vertigo (BPPV), the dislocation or degeneration of otocon
ANZ Journal of Surgery
- Definitive approach to the perforated duodenal strictureWe report the case of a patient with a duodenal perforation secondary to a benign stricture. We made use of intraoperative ultrasound in the acute setting so as to clarify the biliary anatomy and offer definitive surgical management at laparotomy.
Journal of Neuroscience Methods
- Establishing Functional Brain Networks using a Nonlinear Partial Directed Coherence Method to Predict Epileptic SeizuresPublication date: Available online 12 October 2019Source: Journal of Neuroscience MethodsAuthor(s): Qizhong Zhang, Yuejing Hu, Thomas Potter, Rihui Li, Michael Quach, Yingchun ZhangAbstractBackgroundEpilepsy is a neurological disorder characterized by unpredictable seizures that can lead to severe health problems. EEG techniques have shown to be advantageous for studying and predicting epileptic seizures, thanks to their cost-effectiveness, non-i
- Methods for detection of brain injury after photothrombosis-induced ischemia in mice: characteristics and new aspects of their applicationPublication date: Available online 12 October 2019Source: Journal of Neuroscience MethodsAuthor(s): D. Galkov Maksim, V. Gulyaev Mikhail, V. Kiseleva Ekaterina, A. Andreev-Andrievskiy Alexander, R. Gorbacheva LiubovAbstractBackgroundPhotothrombosis is a minimally invasive method for induction of cortical ischemia. However, different ways of applying some methods to assess photothrombosis-induced damage need to be developed.New MethodsWe applied t
- Digital orbitoplethysmograph: a new device to study the regional cerebral circulation using extraorbital plethysmographyPublication date: Available online 12 October 2019Source: Journal of Neuroscience MethodsAuthor(s): Aleš Bezrouk, Tomáš Hosszú, Owen Falzon, Petr Voda, Mikuláš Vachek, Jiří Záhora, Vladimír Mašín, Kenneth P. Camilleri, Jan KremláčekAbstractBackgroundNoninvasive diagnostic methods utilizing pulse wave measurements on the surface of the head are an important tool in diagnosing various types of cerebrovascular disease. The measurement of extraorbita
- Modeling Drug Exposure in Rodents using e-Cigarettes and other Electronic Nicotine Delivery SystemsPublication date: Available online 12 October 2019Source: Journal of Neuroscience MethodsAuthor(s): Cristina Miliano, E. Reilly Scott, Laura B. Murdaugh, Emma R. Gnatowski, Christine L. Faunce, Megan S. Anderson, Malissa M. Reyes, Ann M. Gregus, Matthew W. BuczynskiAbstractSmoking tobacco products is the leading cause of preventable death worldwide. Coordinated efforts have successfully reduced tobacco cigarette smoking in the United States; howe
- Reduced sleep spindle activity in children with primary snoringPublication date: Available online 11 October 2019Source: Sleep MedicineAuthor(s): Pablo E. Brockmann, Oliviero Bruni, Leila Kheirandish-Gozal, David GozalAbstractBackgroundHabitually snoring children are at risk of manifesting disease-related problems even if their sleep studies are overall within normal limits.Study objectivesTo compare sleep spindle activity in children with primary snoring and healthy controls.MethodsSleep spindle activity in
- Relevance of calcification and contrast enhancement pattern for molecular diagnosis and survival prediction of gliomas based on the 2016 World Health Organization classificationPublication date: Available online 12 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Yuhei Michiwaki, Nobuhiro Hata, Masahiro Mizoguchi, Akio Hiwatashi, Daisuke Kuga, Ryusuke Hatae, Yojiro Akagi, Takeo Amemiya, Yutaka Fujioka, Osamu Togao, Satoshi O. Suzuki, Koji Yoshimoto, Toru Iwaki, Koji IiharaAbstractObjectivesThe significance of conventional neuroimaging features for predicting molecular diagnosis and patient survival base
- Excitation modelling using epoch features for statistical parametric speech synthesisPublication date: Available online 12 October 2019Source: Computer Speech & LanguageAuthor(s): M Kiran Reddy, K Sreenivasa RaoAbstractIn this paper, a novel excitation modelling method is proposed for improving the naturalness of statistical parametric speech synthesis (SPSS). In the proposed approach, the excitation or residual signal is parameterized by using features extracted from the epochs. The epoch parameters used in this work are epoch s
Clinical Ophthalmology
OEM Online First
- Prevalence of workplace violence against healthcare workers: a systematic review and meta-analysisWe aim to quantitatively synthesise available epidemiological evidence on the prevalence rates of workplace violence (WPV) by patients and visitors against healthcare workers. We systematically searched PubMed, Embase and Web of Science from their inception to October 2018, as well as the reference lists of all included studies. Two authors independently assessed studies for inclusion. Data were double-extracted and discrepancies were resolved by
- Anti-acidogenic, anti-biofilm and slow release properties of <em>Dodonaea viscosa var. angustifolia</em> flavone stabilized polymeric nanoparticlesPublication date: Available online 12 October 2019Source: Archives of Oral BiologyAuthor(s): Mpho Sebelemetja, Sharon Moeno, Mrudula PatelAbstractObjectiveDental caries is caused by plaque associated oral bacteria including a pioneer species Streptococcus mutans. It has ability to form biofilm and produce acids in the oral cavity. Many oral hygiene products containing plant derived compounds have been investigated for their anti-S. mutans activit
- Destructive maxillary radiolucency in a 20-year-old femalePublication date: Available online 13 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Kevin C. Lee, Scott M. Peters, Jaya S. Pradhan, David M. Alfi, David A. Koslovsky, Elizabeth M. Philipone
- The Effect of the Twin Block Compared With Trigger Point Injections in Subjects With Masticatory Myofascial Pain: A Pilot StudyPublication date: Available online 13 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Sowmya Ananthan, Veena Kanti, Julyana Gomes Zagury, Samuel Y.P. Quek, Rafael BenolielAbstractObjectiveThe twin block, a novel nerve block that blocks the deep temporal and masseteric branches of the trigeminal nerve has been shown to be effective for the short-term management of masticatory myofascial pain. However, l
- Assessment Of Intravertebral Pneumatocysts, Degenerative Joint Disease, And Ponticulus Posticus in the Cervical Spine Through Cone Beam Computed Tomography (CBCT) ExaminationPublication date: Available online 12 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Şehrazat Evirgen, Halil Tolga Yüksel, Gökçe Yüksel, Barış Kaki, Kıvanç KamburoğluAbstractObjectiveTo identify the prevalence and radiological characteristics of intravertebral pneumatocysts (IVP), degenerative joint disease (DJD), and ponticulus posticus (PP) in the cervical spine using CBCT images. The correlations b
- Burning Mouth Syndrome: A Diagnostic ChallengePublication date: Available online 12 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Jacob E. Freilich, Michal Kuten-Shorrer, Nathaniel S. Treister, Sook-Bin Woo, Alessandro VillaAbstractObjectivesTo characterize the diagnostic process that patients with burning mouth syndrome (BMS) undergo, and to identify the potential pitfalls encountered in the work-up and management of BMS.Study DesignA retrospec
- Unusual intraoral cancer with unexpected outcome in a patient with Xeroderma Pigmentosum: an alert for antineoplastic treatmentPublication date: Available online 12 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Mailon Cury Carneiro, Talita de Carvalho Kimura, Elen de Souza Tolentino, Neli Pieralisi, Vanessa Cristina VeltriniAbstractXeroderma pigmentosum (XP) is a rare autosomal disorder characterized by extreme sensitivity to ultraviolet radiation. DNA repair mechanisms are impaired and minimal sun exposure can lead to the d
- Management of regional metastatic disease in cutaneous malignancy of the head and neck. 3. Merkel cell carcinomaPublication date: Available online 12 October 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): C.M. Bowe, B. Gurney, S. Whitaker, C. NewlandsAbstractThis is the third of three articles that give an overview of the current evidence for management of the neck and parotid in patients with cutaneous cancers of the head and neck. In this paper we discuss Merkel cell carcinoma (MCC) and review the latest evidence for management o
bioRxiv Subject Collection: Evolutionary Biology
- From sectors to speckles: The impact of long range migration on gene surfing [NEW RESULTS]Range expansions lead to distinctive patterns of genetic variation in populations, even in the absence of selection. These patterns and their genetic consequences have been well-studied for populations advancing through successive short-ranged migration events. However, most populations harbor some degree of long-range dispersal, experiencing rare yet consequential migration events over arbitrarily long distances. Although dispersal is known to s
- Bacteria primed by antimicrobial peptides develop tolerance and persist [NEW RESULTS]Bacterial resistance to drugs is a growing problem, and one that is inspiring a search for new classes of anti-bacterial compounds. This has generated interest in antimicrobial peptides (AMPs), which are key components of innate immune defences. In contrast to conventional antibiotics, however, little is known about how bacteria respond to AMPs, and whether they modify their phenotypic responses based on their prior experiences. Here, we explore
- Diversification of metazoan Kexin-like proprotein convertases: insights from the leech Helobdella [NEW RESULTS]Intercellular communication is quintessential for multicellularity and often mediated by secreted peptide ligands. In Metazoa, proprotein convertases are a major class of endoproteases partaking in the proteolytic processing of these ligands, which is in turn required for their signaling activities. In vertebrates, the best-studied convertase substrates are neuropeptides, peptide hormones, and members of the TGF{beta}/BMP-family. Each ligand is p
- Evolution in alternating environments with tunable inter-landscape correlations [NEW RESULTS]Natural populations are often exposed to temporally varying environments. Evolutionary dynamics in periodically or stochastically modulated environments have been extensively studied, both theoretically and experimentally, though understanding the effects of temporally varying selection pressures remains challenging. Here we investigate how periodic cycling between a pair of statistically related fitness landscapes affects the evolved fitness of
- Trait-specific trade-offs prevent niche expansion in two parasites [NEW RESULTS]The evolution of host specialization has been studied intensively, yet it is still often difficult to determine why parasites do not evolve broader niches - in particular when the available hosts are closely related and ecologically similar. Here, we used an experimental evolution approach to study the evolution of host specialization, and its underlying traits, in two sympatric parasites: Anostracospora rigaudi and Enterocytospora artemiae, micr
- Ambiguity coding allows accurate inference of evolutionary parameters from alignments in an aggregated state-space [NEW RESULTS]How can we best learn the history of a protein's evolution? Ideally, a model of sequence evolution should capture both the process that generates genetic variation and the functional constraints determining which changes are fixed. However, in practical terms the most suitable approach may simply be the one that combines the convenience of easily available input data with the ability to return useful parameter estimates. For example, we might be
Κυριακή 13 Οκτωβρίου 2019
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