Mon Oct 21, 2019 03:00
Abstract The present study deals with the assessment of essential trace and toxic elements in biological samples (scalp hair) of healthy smoker and non-smoker residents of Lahore (the second most populous city), Pakistan. Human biomonitoring of various trace elements like zinc (Zn), iron (Fe), copper (Cu), chromium (Cr), cadmium (Cd), nickel (Ni), lead (Pb), and arsenic (As) was evaluated in human hair samples of smokers and non-smokers (males and females) as per IFCC criteria....
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Abstract Oštiepok is traditional half-fat semi-hard cheese manufactured in Slovak Republic. In this research, we have analyzed the content of macro-elements (calcium, potassium, magnesium, and sodium) and micro-elements (chromium, copper, iron, manganese, molybdenum, selenium, and zinc) in Oštiepok cheese samples collected from various parts of Slovak Republic. The analysis of Oštiepok cheese samples (n = 19) was carried out by using inductively coupled plasma optical emission...
Thu Oct 24, 2019 03:00
After publication of this paper, the authors determined that the “Acknowledgments” section was omitted. Below is the “Acknowledgments” statement.
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Abstract Halophilic bacteria are good bioresources for halotolerant alkaline enzymes. A multi-domain high-molecular-weight endo-β-1,4-xylanase gene, xylM18, was cloned from a halophilic marine bacterium Marinimicrobium sp. LS-A18. XylM18 is different from any of the functionally reported xylanases. It has a glycosyl hydrolase (GH) 43 domain, a GH10 domain, and two serine-rich linkers, representing a novel family. The gene, encoding 1022 residues, was cloned and heterologously expressed...
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Abstract In this work, recycled paper sludge (RPS), composed of non-recyclable fibres, was used as a carbon source for bacterial nanocellulose (BNC) production. The biomass was enzymatically hydrolysed with Cellic CTec 2 to produce a sugar syrup with 45.40 g/L glucose, 1.69 g/L cellobiose and 2.89 g/L xylose. This hydrolysate was used for the optimization of BNC fermentation by static culture, using Komagataeibacter xylinus ATCC 700178, through response surface methodology (RSM)....
Thu Oct 24, 2019 03:00
Abstract The uptake of exogenous DNA materials through the cell membrane by bacteria, known as transformation, is essential for the genetic manipulation of bacteria and, thus, plays key roles in biotechnological and biological research. The efficiency of natural transformation is very low; therefore, various artificial transformation methods have been developed for simple and efficient bacterial transformation. The basic bacterial transformation method is based on chemical, physical,...
Thu Oct 24, 2019 03:00
We have investigated the relationship between the function of the gene hindsight (hnt), which is the Drosophila homolog of Ras Responsive Element Binding protein-1 (RREB-1), and the EGFR signaling pathway. We report that hnt mutant embryos are defective in EGFR signaling dependent processes, namely chordotonal organ recruitment and oenocyte specification. We also show the temperature sensitive hypomorphic allele hntpebbled is enhanced by the hypomorphic MAPK allele rolled (rl1). We find that hnt...
Thu Oct 24, 2019 23:20
Drosophila melanogaster photoreceptor cells are highly polarized epithelial cells. Their apical membrane is further subdivided into the stalk membrane and the light-sensing rhabdomere. The photo-pigment Rhodopsin1 (Rh1) localizes to the rhabdomere, whereas the apical determinant Crumbs (Crb) is enriched at the stalk membrane. The proteoglycan Eyes shut (Eys) is secreted through the apical membrane into an inter-rhabdomeral space. Rh1, Crb, and Eys are essential for the development of photoreceptor...
Thu Oct 24, 2019 23:20
Prediction of phenotypes from genotypes is an important objective to fulfill the promises of genomics, precision medicine and agriculture. Although it's now possible to account for the majority of genetic variation through model fitting, prediction of phenotypes remains a challenge, especially across populations that have diverged in the past. In this study, we designed simulation experiments to specifically investigate the role of genetic interactions in failure of polygenic prediction. We found...
Thu Oct 24, 2019 23:20
No abstract available
Mon Oct 21, 2019 03:00
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Mon Oct 21, 2019 03:00
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Mon Oct 21, 2019 03:00
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Mon Oct 21, 2019 03:00
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Mon Oct 21, 2019 03:00
Objective: In the field of plastic surgery , accurate and indelible preoperative skin markings of importance reference points and incision sites are essential for precise surgery. Skin markings , hence need to be robust and indelible so as to withstand the surgical site preparation with antiseptic solutions. Method: We evaluated the effect of spraying Cavilon solution on the markings after completion of the marking and before the preoperative surgical site preparation to make the markings...
Mon Oct 21, 2019 03:00
No abstract available
Mon Oct 21, 2019 03:00
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Mon Oct 21, 2019 03:00
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Mon Oct 21, 2019 03:00
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Mon Oct 21, 2019 03:00
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Wed Oct 23, 2019 03:00
Recent Preoperative Concussion and Postoperative Complications: A Retrospective Matched-cohort Study
Background: Physiological alterations during the perianesthetic period may contribute to secondary neurocognitive injury after a concussion. Methods: Patients exposed to concussion and who received an anesthetic within 90 days were matched to unexposed patients without concussion. Intraoperative and postoperative events were compared. Subgroup analyses assessed relationships among patients with a concussion in the prior 30, 31 to 60, and 61 to 90 days and their respective unexposed matches....
Wed Oct 23, 2019 03:00
No abstract available
Wed Oct 23, 2019 03:00
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Wed Oct 23, 2019 03:00
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Wed Oct 23, 2019 03:00
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Wed Oct 23, 2019 03:00
Background: Positive-pressure myelogram (PPM) is an emerging radiologic study used to localize spinal dural defects. During PPM, cerebrospinal fluid pressure (CSFp) is increased by injecting saline with contrast into the cerebrospinal fluid. This has the potential to increase intracranial pressure and compromise cerebral perfusion. Methods: We performed a retrospective chart review and analysis of 11 patients. The aim was to describe the periprocedural anesthetic management of patients undergoing...
Wed Oct 23, 2019 03:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b02100
Thu Oct 24, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03210
Thu Oct 24, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b02702
Thu Oct 24, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b02992
Thu Oct 24, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03281
Thu Oct 24, 2019 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.9b03896
Thu Oct 24, 2019 07:00
Publication date: Available online 24 October 2019Source: Human PathologyAuthor(s): Brett M. Lowenthal, Katie S. Nason, Arjun Pennathur, James D. Luketich, Reetesh K. Pai, Jon M. Davison, Changqing MaSummaryEsophageal adenocarcinoma often presents at an advanced stage and has a dismal prognosis. Current prognostic markers have limited utility. ARID1A is implicated as a tumor suppressor gene in esophageal adenocarcinoma. Loss of ARID1A expression correlates with DNA mismatch repair (MMR) protein deficiency...
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Publication date: Available online 23 October 2019Source: Human PathologyAuthor(s): Kimmie Rabe, Olivia L Snir, Veerle Bossuyt, Malini Harigopal, Romulo Celli, Emily S ReisenbichlerSummaryThe AJCC Cancer Staging Manual 8th edition included tumor grade in the pathologic prognostic stage for breast carcinomas. Due to the known subjectivity of tumor grading, we aimed to assess the degree of interobserver agreement for invasive carcinoma grade among pathologists and determine its effect on pathologic...
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Publication date: Available online 23 October 2019Source: Human PathologyAuthor(s): Gregory T. MacLennan, Liang ChengSummaryThose who are knowledgeable in cosmology inform us that the expansion of the universe is such that the velocity at which a distant galaxy is receding from the observer is continually increasing with time. We humbly paraphrase that as “The bigger the universe gets, the faster it gets bigger”. This is an interesting analogy for the expansion of knowledge in the field of renal...
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Publication date: Available online 23 October 2019Source: Human PathologyAuthor(s): Ji Dong K. Bai, Sruthi Babu, Lucia Roa-Peña, Wei Hou, Ali Akalin, Luisa F. Escobar-Hoyos, Kenneth R. ShroyerSummaryKeratin 17 (K17) has been established as a negative prognostic biomarker in cervical and ovarian cancers but has not previously been evaluated as a prognostic biomarker in endometrial adenocarcinoma. The association of K17 with decreased patient survival may be explained in part by the discovery that...
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Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1022-9874Non-classical thyroid hormone signalling via cell surface receptor integrin αvβ3, expressed on most cancer cells and proliferating endothelial cells, has been shown to drive tumour cell proliferation and survival, as well as angiogenesis. Tumours develop within a complex microenvironment that is composed of many different cell types, including mesenchymal stem cells. These multipotent progenitor cells actively home to growing tumours where they...
Thu Oct 24, 2019 02:00
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