Abdalla M Attia, Hossam A El Hamid Yassien, Bilal A El-Mohsen Montaser, Mohammed M El-MeligiMenoufia Medical Journal 2019 32(3):1009-1012Objective The aim of this study was to determine whether an abnormality in the serum levels of kisspeptin is associated with oligospermia and male infertility. Background The study of kisspeptin has yielded a new concept on the physiology of the hypothalamic–pituitary–testicular axis and thus the sexual and reproductive functions of men. Patients and methods ...
Samia H Kandel, Iman A Ahmedy, Suzan A Al-Hassanin, Samar S H El-GazzarMenoufia Medical Journal 2019 32(3):784-789 Objective The aim of this study was to evaluate the role of feline McDonough sarcoma (FMS)-like tyrosine kinase 3 (FLT3) in acute myeloblastic leukemia (AML). Background AML is the most common acute leukemia affecting adults, and its incidence increases with age. FLT3 belongs to the class III receptor kinase family, which plays an essential role in hematopoiesis, driving differentiation...
Fady M El-Gendy, Wael A Bahbah, Eman El-Sayed Al KaforyMenoufia Medical Journal 2019 32(3):1059-1063Objective The aim was to evaluate the role of ursodeoxycholic acid (UDCA) on neonatal indirect hyperbilirubinemia treated with phototherapy. Background Hyperbilirubinemia is a common neonatal problem. The present study aimed to investigate the role of UDCA on neonatal hyperbilirubinemia treated with phototherapy. Participants and methods This randomized controlled clinical trial was conducted...
Ahmed A Reda, Waleed A Ibrahim, Ahmed O ElsisyMenoufia Medical Journal 2019 32(3):790-796Objective The objective of our study was to estimate the effect of adiponectin (ADPN) and highly sensitive C-reactive protein (hsCRP) level on the severity of coronary artery disease (CAD) in patients with chronic stable angina. Materials and methods MEDLINE databases (PubMed, Journal of Clinical Endocrinology and Metabolism, British Medical Journal, Journal of American College of Cardiology, and European...
Ahmed A Ali, Ibrahim I El-Mahalawy, Samy S El-Dahdouh, Mona S Habib, Fatma S El-FakharanyMenoufia Medical Journal 2019 32(3):1104-1107Objective The aim was to assess the level of tumor necrosis factor-α (TNF-α) in patients with active pulmonary tuberculosis (TB) and its relation to BMI; different radiological features whether the lesion is minimally, moderately advanced, and far advanced; and to follow-up the level of TNF-α. Background One of the most important and common complaints of patients...
Hala M Badran, Naglaa F Ahamed, Abd Elmoaty G. KishkMenoufia Medical Journal 2019 32(3):797-802Objective This study aimed to assess the causes, risk factors, outcome, and recommendation of patients with coronary artery disease without prior obstruction. Materials and methods Medline databases (PubMed, Circulation, American Society of Echocardiography, Journal of American Colleague of Cardiology, and ScienceDirect) and also materials available on the internet. The search was performed in the...
Hassan G Farahat, Khalid E. S. Ahmed, Omnia A AttiaMenoufia Medical Journal 2019 32(3):1149-1153 Objective The aim of this study was to assess corneal biomechanical properties using the ocular response analyzer (ORA) in myopic young individuals with normal topography. Background The development in corneal refractive surgeries raises the necessity of studying corneal properties in detail. Corneal viscoelasticity, in terms of corneal biomechanics, is measured by ORA through the analysis of...
Ahmed A Reda, Waleed A Ibrahim, Markos Z SalamaMenoufia Medical Journal 2019 32(3):803-811 Objective To evaluate the relations between preprocedural neutrophil/lymphocyte (N/L) ratio and in-hospital outcomes in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). Data sources We utilize the medical journals, medical text books, and Medline databases (PubMed, Medscape, and Science Direct) which have updated research with keywords...
Gehan K El-Saeed, Rasha I Noreldin, Ayman A Alghoraieb, Hanan A AhmedMenoufia Medical Journal 2019 32(3):972-977Objective The aim was to evaluate the level of human chitinase-3-like protein (YKL-40) in patients with hepatitis C virus infection and observe its level in hepatic fibrosis. Background Hepatic fibrosis results from long-standing liver damage, and it represents a major health care burden worldwide. In recent years, there has been increasing interest in identifying and describing hepatic...
Ali M Elshafie, Dalia M El-Lahony, Zein A Omar, Wael A Bahbah, Hanem R M GhetasMenoufia Medical Journal 2019 32(3):812-817Objective The study aimed to review the different types of nutrition in critically ill pediatric patients. Data sources Medline databases (PubMed, Medscape, Science Direct, EMF-Portal, Google Scholar) and all materials available in the Internet from 2001 to 2014 were searched. Study selection The initial search presented 150 articles of which 50 met the inclusion criteria....
Gehan K El-Saeed, Walid A Shehab El-Deen, Belal A Montasr, Thoria A Omar, Doaa S MohamedMenoufia Medical Journal 2019 32(3):996-1003Objective To investigate urinary podocalyxin (PCX) and cyclophilin A (CypA) as useful markers for early detection of type 2 diabetic nephropathy (DN). Background PCX is a transmembrane protein that localizes to the apical cell of glomerular podocytes. PCX maintains podocytes shape. PCX is shed from injured podocytes into urine as small vesicles. CypA is an 18-kD...
Fady M El Gendy, Mahmoud A EL-Hawy, Nehal K El ShennawyMenoufia Medical Journal 2019 32(3):818-822 Objectives The study aimed to demonstrate the critical role of hepcidin in regulation of iron metabolism in various types of anemia. Data sources Medline databases (PubMed, Science Direct, Medscape) and all materials available in the Internet from 2007 to 2017 were searched. Study selection The initial search presented 38 articles, of which 11 met the inclusion criteria. The articles studied...
Mohammed A Shoeib, Ola A Bakry, Sally M El-Hefnawy, Douaa S AlsaadanyMenoufia Medical Journal 2019 32(3):1019-1024 Objective The aim was to investigate the association between endothelin-1 (ET-1) gene polymorphism and vitiligo occurrence or increased vitiligo risk in Egyptian population. Background ET-1 is a keratinocyte-derived cytokine, which also has been defined as a strong mitogen and melanogen for human melanocytes and a potent stimulant of melanocyte proliferation, melanogenesis, and...
Sabry Shoeib, Mohamed A El Hafez, Alaa Efat, Fatma NoamanMenoufia Medical Journal 2019 32(3):823-828Objective The aim was to study the relationship between acquired von Willebrand syndrome (AvWS) and other diseases. Materials and methods Medline, Embase, and PubMed databases were searched and also material available in the internet was made use of. The search was performed on 1 May 2016 and included articles published ahead of print with no language restrictions. The search was performed in...
Ghada M Elmashad, Wael A Bahbah, Waleed A Mousa, Mostafa M ShalabyMenoufia Medical Journal 2019 32(3):1043-1050Objective The aim of this study was to compare chest ultrasonography with chest radiography (CXR) in the diagnosis of children with pneumonia. Background In Egypt, pneumonia and other acute respiratory infections were the causes of death in ∼19% of children younger than 5 years. According to current guidelines, pneumonia is diagnosed by clinical history, respiratory rate, fever, respiratory...
Mohammed A Basha, Iman A Seleit, Ola A Bakry, Rehab M Samaka, Heba Allah S K BazidMenoufia Medical Journal 2019 32(3):829-835Objective The aim of this study was to assess the role of Notch signaling in both health skin and pathogenesis and management of skin diseases. Materials and methods PubMed and all materials on the internet from 2000 to 2017 were searched. The initial search presented 101 articles, of which 49 met the inclusion criteria: clinical trial types II and III, published in English...
Ghada M El Mashad, Hanan M El Sayed, Wael A El ShafieMenoufia Medical Journal 2019 32(3):1071-1077Objective The aim was to evaluate the predictive value of cord blood albumin and bilirubin in identifying infants greater than or equal to 35 weeks for subsequent hyperbilirubinemia. Background Hyperbilirubinemia is the most common cause for readmission during the early neonatal period. Early discharge of healthy term newborns after delivery has become a common practice for socioeconomic reasons. ...
Hala M Badran, Ali M Alamin, Naglaa F Ahmed, Taher S Abdel KareemMenoufia Medical Journal 2019 32(3):836-843Objectives The objective of this paper is to detect changes in left ventricular (LV) mechanics after surgical myectomy in patient with hypertrophic obstructive cardiomyopathy (HOCM). Background Septal myectomy is the gold standard method to relieve LV outflow tract pressure gradient in patients with HOCM. Myocardial mechanics are abnormal in those patients, demonstrating low longitudinal...
Ghada M Elmashad, Hanan M Elsayed, Zein A Omar, Eman A Badr, Osama M OmranMenoufia Medical Journal 2019 32(3):1094-1098Objective To evaluate the serum amyloid A (SAA) as an early and accurate diagnostic marker in neonatal sepsis. Background The early and efficient diagnosis of neonatal sepsis in high-risk neonates remains a difficult task as the clinical signs are nonspecific, complete blood count parameters and C-reactive protein (CRP) have low sensitivity, also difficulty of its diagnosis...
Abdullah M Kamal, Ahmed A Mostafa, Bayoumi M BayoumiMenoufia Medical Journal 2019 32(3):844-850Objective The aim of this work was to assess the relationship between the level of glycated hemoglobin (HbA1c) and the severity of coronary artery disease (CAD) among diabetic patients and perform a comparison with nondiabetic patients. Background Diabetes mellitus and coronary heart disease are closely associated and generally coexist. The severity CAD is directly related to the quality of glucose...
Mohamed A Nouh, Moamena S El-Hamouly, Safaa A Mohamed, Ahmad Y. H. MetwallyMenoufia Medical Journal 2019 32(3):1113-1118Objective This study aimed to assess the role of right liver lobe diameter by ultrasound/albumin ratio in the prediction of esophageal varices (OV) in cirrhotic patients. Background OV often develop in cirrhotic patients. Varices rupture leading to variceal bleeding represents the most lethal complication of cirrhosis. Right liver lobe diameter/albumin (RLLD/Alb) ratio is...
Abdallah M Kamal, Naglaa F Ahmed, George S KamilMenoufia Medical Journal 2019 32(3):851-854Aim The aim of this study was to compare the efficacy and rapidity of recent-onset atrial fibrillation (AF) conversion by oral propafenone versus an intravenous infusion of amiodarone. Background Amiodarone and propafenone are the most widely used drugs in Egypt for the pharmacological cardioversion of AF. Patients and methods Fifty patients with recent-onset AF – within less than 48 h – were investigated....
Samir M. H. Kahla, Ahmed Gaber, Mahmoud M. A. Al-RahawyMenoufia Medical Journal 2019 32(3):1137-1141Objective The aim of this paper was to evaluate the effectiveness of prophylactic antibiotics in the prevention of postoperative wound infection after Lichtenstein open mesh inguinal hernia repair. Background Inguinal hernia is one of the most common conditions encountered in clinical practice. Mesh repair is becoming the most popular technique for the repair of inguinal hernia. A surgical-site...
Mahmoud A Soliman, Morad B Mena, Gerges R ThabetMenoufia Medical Journal 2019 32(3):855-860Objective The aim of this study was to evaluate longitudinal strain by speckle tracking in hypertensive patients with strain ST-T on ECG. Background Hypertension causes ST-T changes on ECG which may predict subclinical systolic dysfunction detected by two-dimensional speckle tracking. Patients and methods Longitudinal strain analysis was done in 82 hypertensive patients, who were divided into three...
Rasheedat M Ibraheem, Damilola M Oladele, Salihu S Mohammed, Mohammed B Abdulkadir, Wahab B. R. Johnson, Abdulwasiu G OmotoshoMenoufia Medical Journal 2019 32(3):1157-1160Tuberculosis (TB) remains a ravaging disease, particularly in the low-income countries, with a protean manifestation in children. Thus, a high index of suspicion is the key to clinching the diagnosis when presentation is in a rare form such as laryngeal TB. In this study, the case report of a 10-year-old female child with laryngeal...
Fahima M Hassan, Ahmed A Khattab, Mahmoud A Soliman, Rania S El-Zayat, Marwa G S FeteihMenoufia Medical Journal 2019 32(3):861-867Objective To evaluate left ventricular function using speckle tracking echocardiography (STE) in pediatric patients with end-stage renal disease (ESRD) with preserved left ventricular ejection fraction. Background ESRD is considered a leading cause of cardiovascular morbidity and mortality in pediatric patients. With the help of newer echocardiographic modalities...
Seham Ahmed Zaky Khodair, Yassin S Yassin, Rasha I Noor El-Din, Asmaa A. A. SabikMenoufia Medical Journal 2019 32(3):967-971Objective The objective of this study was to evaluate fibroblast growth factor 23 (FGF23) expression in patients with chronic kidney disease (CKD) and its effect on diagnosis, grading, and prognosis of patients. Background CKD is recognized as a major public health problem in which there is progressive loss in renal function over a period of months or years. FGF23 is a...
Ahmed A E Emara, Alaa-Eldeen A Hataba, Ahmed M Elkersh, Ahmad M Mahmoud ElsheikhMenoufia Medical Journal 2019 32(3):868-875Objective The aim of this study was to define the preinterventional parameters for procedural success of chronic total occlusion (CTO) coronary angioplasty. Background CTOs are encountered in 15–30% of patients undergoing coronary angiography. Compared with failed CTO angioplasty, successful CTO angioplasty has been associated with improvement in angina and left ventricular...
Waled M Fathy, Iman A Ahmedy, Shaimaa M Motawe, Rasha A El MorsyMenoufia Medical Journal 2019 32(3):978-982 Objective We aimed to study the differentiation of mesenchymal stem cells (MSCs) into cardiomyocytes using azacytidine. Background Ischemic injury of cardiomyocytes results in heart failure, as cardiomyocytes do not have the ability to regenerate after death. This has prompted interest in identifying cells capable of replacing the injured myocardium with healthy cells. The ideal candidate...
Mohamed R El Kholy, Waleed A Mousa, Nagwan R MishmishaMenoufia Medical Journal 2019 32(3):876-880 Objective The aim was to evaluate breast lesions using mammography (MG) and ultrasonography (USG) independently and in combination in women with dense breasts. Background Women with dense breasts are at higher risk of developing breast cancer and at greater risk of cancer being not detected because of masking of the radiological signs of cancer by increased density. Therefore, multiple imaging...
Waled M Fathy, Rasha I NourEldin, Gehad H ShalbyMenoufia Medical Journal 2019 32(3):991-995Objectives The objective of this article was to differentiate mesenchymal stem cells (MSCs) into cardiomyocytes. Background Cardiomyopathies resulted in permanent loss of cardiomyocytes as it had no ability of regeneration. This made MSCs a promising tool for cellular therapy because of their ability of self-renewal and multipotency. MSCs were considered ideal for cellular cardiomyoplasty as they can...
El-Sayed M El-Sayed, Mohmad S Abdullah, Hamed G AliMenoufia Medical Journal 2019 32(3):881-888Background Conventional MRI has an established role in gynecologic imaging. However, increasing clinical demand for improved lesion characterization and disease mapping to optimize patient management has resulted in the incorporation of newer sequences, such as diffusion-weighted imaging (DWI), into routine protocols for pelvic MRI. DWI provides functional information on the microenvironment of water in...
Khaled A Khalifa, Omaima M Abbas, Raafat M Abdlfattah, Suzan A El-Hassanein, Amira M. F. Shehata, Sally S Mandour EsawyMenoufia Medical Journal 2019 32(3):1004-1008Objectives To measure the expression levels of microRNA-451 (miR-451) in patients with chronic myeloid leukemia (CML) and to correlate miR-451 expression levels with response to imatinib mesylate (IM)-based therapeutic protocol. Background miRNAs are regulatory RNAs that have been classified as crucial players of cancer initiation...
Aya H El-Sabbagh, Mohammed S El-Zawawi, Yasmin H HemidaMenoufia Medical Journal 2019 32(3):889-894Objective To evaluate role of duplex Doppler ultrasound in assessing arteriovenous graft (AVG) function, detecting complications and analyzing the resistance index (RI) and flow in the afferent artery. Background End-stage renal disease causes serious health problems all over the world. The numbers of patients requiring dialysis have grown. In Egypt, it is the cause of 1.3% of all deaths, with...
Mostafa A Hammam, Azza G Antar, Asmaa G Abdou, Reem A. Abd El-Aziz HassanMenoufia Medical Journal 2019 32(3):1013-1018 Objective The present study aimed at evaluating microvascular density (MVD) in involved and uninvolved skin of patients with psoriasis. Background Psoriasis is a chronic inflammation skin disease characterized by accelerated proliferation, abnormal differentiation, and increased angiogenesis. The angiogenesis is related to many factors in the pathogenesis of psoriasis. The...
Adel M El-Wakeel, Waleed A F Mousa, Sara M SultanMenoufia Medical Journal 2019 32(3):895-900Objective The aim of this study was to detect the role of contrast-enhanced computed tomography (CT) in the diagnosis of acute pancreatitis according to the revised Atlanta classification. Background Imaging plays a very important role in the management of pancreatitis. It assists diagnosis and in differentiation of the severity of pancreatitis. Besides, it helps to detect and manage the associated complications...
Mohamed A Gaber, Hesham N Khaled, Manal M. A. NassarMenoufia Medical Journal 2019 32(3):1025-1029Objective The objective of this study was to study the effects of pornography on married couples in their sexual and social live. Background Pornography has long been a major problem in our society, but since the arrival of the internet it has grown to proportions no one could have imagined. Participants and methods The study included 300 married men and women selected randomly with age ranging...
Mahmoud Abd El-Aziz Kora, Ahmad M Zahran, Khaled M A El-Zorkany, Ahmad M EwedahMenoufia Medical Journal 2019 32(3):901-905Objective To compare between dialysis modalities and their effect on anemia control, chronic kidney disease mineral bone disease (CKD-MBD) control, dialysis adequacy, and dialysis complication on end-stage renal disease (ESRD) patients. Background Hemodialysis (HD) and peritoneal dialysis (PD) are dialysis modalities for ESRD patients that have its own effect on patients....
Ali M El-Shafie, Dalia M El Lahony, Zein A Omar, Mohamed A. M. DagherMenoufia Medical Journal 2019 32(3):1037-1042Objective The aim was to screen the intelligence level among primary school children using 'draw-a-person (DAP) test' in Dakahlia Governorate. Background For more than 100 years, clinicians and psychologists have studied children's drawing as a measure of one's cognitive ability. In 1926, Florence Goodenough developed a drawing test called the DAP test. The DAP test consists of...
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