Publication date: Available online 4 October 2019Source: Auris Nasus LarynxAuthor(s): Hirohito Umeno, Masamitsu Hyodo, Tomoyuki Haji, Hirotaka Hara, Mitsuyoshi Imaizumi, Miyoko Ishige, Masanobu Kumada, Kiyoshi Makiyama, Noriko Nishizawa, Koichiro Saito, Osamu Shiromoto, Atsushi Suehiro, Goro Takahashi, Ichiro Tateya, Koichi Tsunoda, Koichi OmoriAbstractObjectiveTo develop a summary of the first version of the Clinical Practice Guideline of Voice Disorders for Diagnosis, Management, and Treatment...
Fri Oct 04, 2019 16:41
Condition: Esophageal Squamous Cell CarcinomaIntervention: Radiation: Simultaneous integrated boost intensity-modulated chemoradiotherapySponsor: Fudan UniversityRecruiting
Fri Oct 04, 2019 14:08
Condition: Psoriatic ArthritisInterventions: Drug: Filgotinib; Drug: Placebo to match filgotinibSponsors: Gilead Sciences; Galapagos NVNot yet recruiting
Fri Oct 04, 2019 14:08
Condition: Oropharyngeal CancerInterventions: Drug: Cisplatin; Drug: Durvalumab; Procedure: Radiotherapy; Procedure: Dose-escalated radiotherapySponsors: University of Birmingham; AstraZenecaRecruiting
Fri Oct 04, 2019 14:08
Condition: Psoriatic ArthritisInterventions: Drug: Filgotinib; Drug: Adalimumab; Drug: Placebo to match filgotinib; Drug: Placebo to match adalimumabSponsors: Gilead Sciences; Galapagos NVNot yet recruiting
Fri Oct 04, 2019 14:08
Abstract Purpose A personalised transportable folding device for seating (DATP) on a standard seat was developed by an occupational therapist at the Toulouse University Hospital Centre (patent no. WO 2011121249 A1) based on the hypothesis that the use of a seat to assist with better positioning on any chair during meals modifies the sitting posture and has an impact on cervical statics which increases the amplitude of movements of the...
Fri Oct 04, 2019 03:00
Abstract Purpose The aim of the study was to investigate the change in health-related quality of life (HRQoL) after canal wall up cholesteatoma surgery, using the Glasgow Benefit Inventory (GBI). Methods Data from a consecutive group of 47 adults scheduled for primary cholesteatoma surgery using canal wall up (CWU) with obliteration, from January 2005 to...
Fri Oct 04, 2019 03:00
Fri Oct 04, 2019 03:00
Abstract In P63‐related ectodermal dysplasias (ED), the clinical characteristics focus on extra‐cutaneous manifestations. The dermatological phenotype remains incompletely characterized. We report the dermatological features of 22 patients carrying a TP63 mutation. Erosions, erythroderma and pigmentary anomalies are characteristic of P63‐related ED. Our data suggest that patients might be classified into 2 major P63‐related disorders: AEC and EEC. RHS and ADULT represent mild AEC and EEC forms respectively.
Fri Oct 04, 2019 12:38
Abstract Background Papillary thyroid cancer (PTC) incidence continues to rise. We describe the natural history of untreated PTC patients. Methods Retrospective case series of 31 untreated PTC patients. Results We identified 31 untreated patients from the Kaiser Permanente Cancer Registry with PTC from 1973 to 2010. Patients were categorized as low risk (n = 16), high risk (n = 12), or low risk but medically contraindicated for surgery (n = 3). At diagnosis, 7 (58.3%) in the high‐risk...
Fri Oct 04, 2019 16:51
Abstract Background Most of the primary sphenoid sinus tumors present with locally advanced stages with involvement of adjacent critical structures and are not amenable to radical resection. We sought to evaluate the safety and efficacy of carbon‐ion radiotherapy (C‐ion RT) for sphenoid sinus malignancies. Methods This is a retrospective analysis of 22 patients of primary sphenoid carcinomas treated with definitive C‐ion RT. Results Adenoid cystic carcinoma was the most common histology...
Fri Oct 04, 2019 16:40
Abstract Background The purpose of this study was to evaluate the national rate of treatment refusal in head and neck cancer (HNC). Methods The National Cancer Database was queried for nonmetastatic squamous cell carcinoma of the head and neck. Oncologic therapy referred to receipt of surgery, radiotherapy, or chemotherapy. Results Compared to the 230 424 patients who received treatment, 2965 (1.3%) were reported to have refused definitive therapy. Predictors included older age, female...
Fri Oct 04, 2019 16:39
Related ArticlesIn response to the 'Letter to the Editor' on the paper 'Aging effect on sleepiness and apneas severity in patients with obstructive sleep apnea syndrome: a meta-analysis study'. Eur Arch Otorhinolaryngol. 2019 Oct 04;: Authors: Iannella G, Magliulo G, De Vito A, Vicini C PMID: 31584116 [PubMed - as supplied by publisher]
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Related ArticlesElective neck dissection in adenoid cystic carcinoma of head and neck: yes or no? A systematic review. Eur Arch Otorhinolaryngol. 2019 Oct 03;: Authors: Luksic I, Suton P Abstract PURPOSE: Adenoid cystic carcinoma of head and neck (AdCCHN) is salivary gland malignancy known for its slow progression accompanied with perineural invasion, rare lymphatic spread to the neck, high rate of local recurrence and delayed onset of distant metastases....
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Related ArticlesSingle-cycle induction chemotherapy before chemoradiotherapy or surgery in functionally inoperable head and neck squamous cell carcinoma: 10-year results. Eur Arch Otorhinolaryngol. 2019 Oct 03;: Authors: Breheret M, Lubgan D, Haderlein M, Hecht M, Traxdorf M, Schmidt D, Müller S, Kitzsteiner C, Kuwert T, Iro H, Fietkau R, Semrau S Abstract INTRODUCTION: The response to induction chemotherapy (IC) predicts local control after conservative...
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J Neurol Surg BDOI: 10.1055/s-0039-1696724 Purpose Radiation therapy represents an uncommon but important component of treatment plans for some pituitary adenomas (PAs). Although radiation therapy has been used to treat pituitary adenomas for over a century, general trends in the usage of radiation therapy for this purpose have not been reviewed. Additionally, there are few large studies evaluating how radiation therapy is used for the treatment of these benign tumors. Investigating these...
Fri Oct 04, 2019 02:00
J Neurol Surg BDOI: 10.1055/s-0039-1695062Chordomas of the cranial base are locally destructive tumors since they are surrounded by significant complex neurovascular structures. Thus, their surgical removal is challenging, recurrence rates are high, and their therapeutic strategies remain controversial.In this video, we present a 47-year-old man with a recent onset of swallowing difficulties, hoarseness, and weight loss for several weeks. In the neurological examination, he had complete paralysis...
Fri Oct 04, 2019 02:00
Abstract Temporomandibular joint (TMJ) arthritis is a common cause of orofacial pain with distressing symptoms. The patients most commonly females are often anxious and worried due to the typical gritty sound produced during chewing moments. In other cases there is pain followed by decreased mouth opening. Currently the treatment is not standardised though the clinicians are treating these disorders either by oral medications; splintage or by injections. Though local injection...
Fri Oct 04, 2019 03:00
Objective: To assess long-term results and present experience with a high-porosity hydroxyapatite ceramic for obliterating large open mastoid cavities. Study-Design: Cross-sectional cohort study. Setting: Tertiary academic referral center. Patients: All patients who underwent tympanomastoid surgery for chronic middle ear disease or revision surgery with reduction of an open mastoid cavity using a highly porous hydroxyapatite matrix material (HMM) between May 2005 and June 2013 were...
Thu Oct 03, 2019 03:00
Musical Ear Syndrome and Cochlear Explantation: Case Report and Proposal for a Theoretical Framework
Objective: To report an unusual case of musical ear syndrome, and to present a theoretical framework for this condition, merging information from the presented case and from former case reports. Patient: A 67-year-old semi-professional musician, who underwent bilateral cochlear implantation and experienced musical ear syndrome, i.e., hearing music, where none was present. Interventions: Cochlear implantation with a bilateral cochlear implant, and cochlear explantation 17 months later. ...
Tue Oct 01, 2019 03:00
Publication date: Available online 4 October 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): James T. Albright, Newton O. Duncan, Abel M. Smerica, Joseph L. EdmondsAbstractPediatric tonsillectomy is a frequently performed procedure using a variety of surgical techniques. Despite decades of modern surgical experience and advances in tools and techniques, a consensus on which technique is superior for minimizing complications has not been established. In a 2014 study, the...
Fri Oct 04, 2019 16:05
Publication date: Available online 4 October 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Tomomi Yamamoto-Fukuda, Naotaro Akiyama, Hiromi KojimaAbstractObjectiveThe middle ear epithelium is derived from the neural crest and endoderm, which line distinct regions of the middle ear cavity. In this study, we investigated the localization of stem/progenitor cells in the middle ear mucosa of adult mice and the effects of keratinocyte growth factor (KGF) on the cell kinetics...
Fri Oct 04, 2019 16:05
Publication date: Available online 4 October 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Beata Zelazowska-Rutkowska, Bozena Skotnicka, Elzbieta Hassmann-Poznanska, Bogdan CylwikAbstractObjectivesThe aim of the current study was to assess the levels of MMP-8, MMP-9 and TIMP-1 in the group of children with adenoids who suffered from exudative otitis media.MethodsThe study included 20 patients (10 females and 10 males) with adenoid hypertrophy coexisting with otitis...
Fri Oct 04, 2019 16:05
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