PeerJ Computer Science
- Different expression pattern of flowering pathway genes contribute to male or female organ development during floral transition in the monoecious weed Ambrosia artemisiifolia L. (Asteraceae)The highly allergenic and invasive weed Ambrosia artemisiifolia L. is a monoecius plant with separated male and female flowers. The genetic regulation of floral morphogenesis is a less understood field in the reproduction biology of this species. Therefore the objective of this work was to investigate the genetic control of sex determination during floral organogenesis. To this end, we performed a genome-wide transcriptional profiling of vegetati
- The impact of artificial intelligence in medicine on the future role of the physicianThe practice of medicine is changing with the development of new Artificial Intelligence (AI) methods of machine learning. Coupled with rapid improvements in computer processing, these AI-based systems are already improving the accuracy and efficiency of diagnosis and treatment across various specializations. The increasing focus of AI in radiology has led to some experts suggesting that someday AI may even replace radiologists. These suggestions
- Identification of potential biomarkers and pivotal biological pathways for prostate cancer using bioinformatics analysis methodsBackground Prostate cancer (PCa) is a common urinary malignancy, whose molecular mechanism has not been fully elucidated. We aimed to screen for key genes and biological pathways related to PCa using bioinformatics method. Methods Differentially expressed genes (DEGs) were filtered out from the GSE103512 dataset and subjected to the gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses. The protein–pro
- The clinical significance of collagen family gene expression in esophageal squamous cell carcinomaBackground Esophageal squamous cell carcinoma (ESCC) is a subtype of esophageal cancer with high incidence and mortality. Due to the poor 5-year survival rates of patients with ESCC, exploring novel diagnostic markers for early ESCC is emergent. Collagen, the abundant constituent of extracellular matrix, plays a critical role in tumor growth and epithelial-mesenchymal transition. However, the clinical significance of collagen genes in ESCC has
- Multiplexed ISSR genotyping by sequencing distinguishes two precious coral species (Anthozoa: Octocorallia: Coralliidae) that share a mitochondrial haplotypeBackground Precious corals known as coralliid corals (Anthozoa: Octocorallia) play an important role in increasing the biodiversity of the deep sea. Currently, these corals are highly threatened because of overfishing that has been brought on by an increased demand and elevated prices for them.The deep sea precious corals Pleurocorallium elatius and P. konojoi are distributed in Japanese waters and have distinct morphological fea
- The cuticle inward barrier in Drosophila melanogaster is shaped by mitochondrial and nuclear genotypes and a sex-specific effect of dietAn important role of the insect cuticle is to prevent wetting (i.e., permeation of water) and also to prevent penetration of potentially harmful substances. This barrier function mainly depends on the hydrophobic cuticle surface composed of lipids including cuticular hydrocarbons (CHCs). We investigated to what extent the cuticle inward barrier function depends on the genotype, comprising mitochondrial and nuclear genes in the fruit fly Drosophil
- Physiological and gene transcription assays to assess responses of mussels to environmental changesCoastal regions worldwide face increasing management concerns due to natural and anthropogenic forces that have the potential to significantly degrade nearshore marine resources. The goal of our study was to develop and test a monitoring strategy for nearshore marine ecosystems in remote areas that are not readily accessible for sampling. Mussel species have been used extensively to assess ecosystem vulnerability to multiple, interacting stressor
- The association between serum lipids and risk of premature mortality in Latin America: a systematic review of population-based prospective cohort studiesObjective To synthetize the scientific evidence on the association between serum lipids and premature mortality in Latin America (LA). Methods Five data bases were searched from inception without language restrictions: Embase, Medline, Global Health, Scopus and LILACS. Population-based studies following random sampling methods were identified. The exposure variable w
- HIF inhibitor topotecan has a neuroprotective effect in a murine retinal ischemia-reperfusion modelPurpose The therapeutic approach for retinal ganglion cell (RGC) degeneration has not been fully established. Recently, it has been reported that hypoxia-inducible factor (HIF) may be involved with retinal neurodegeneration. In this study, we investigated neuroprotective effects of a HIF inhibitor against RGC degeneration induced in a murine model of retinal ischemia-reperfusion (I/R).
Head and Neck
- Predominance of M1 subtype among tumor-associated macrophages in phenotypically aggressive sporadic vestibular schwannoma.Related ArticlesPredominance of M1 subtype among tumor-associated macrophages in phenotypically aggressive sporadic vestibular schwannoma. J Neurosurg. 2019 Oct 04;:1-9 Authors: Perry A, Graffeo CS, Carlstrom LP, Raghunathan A, Driscoll CLW, Neff BA, Carlson ML, Parney IF, Link MJ, Van Gompel JJ Abstract OBJECTIVE: Tumor-associated macrophages (TAMs) have been implicated as pathologic actors in pheno
- Hospital utilization for orbital and intracranial complications of pediatric acute rhinosinusitis.Related ArticlesHospital utilization for orbital and intracranial complications of pediatric acute rhinosinusitis. Int J Pediatr Otorhinolaryngol. 2019 Sep 26;128:109696 Authors: Levy DA, Nguyen SA, Harvey R, Hopkins C, Schlosser RJ Abstract BACKGROUND: Orbital and intracranial complications of pediatric acute rhinosinusitis (ARS) are uncommon. With a risk of significant morbidity, hospital utilizati
- Cutaneous keratinocyte cancers of the head and neck: Epidemiology, risk factors and clinical, dermoscopic and reflectance confocal microscopic features.Related ArticlesCutaneous keratinocyte cancers of the head and neck: Epidemiology, risk factors and clinical, dermoscopic and reflectance confocal microscopic features. Oral Oncol. 2019 Oct 01;98:109-117 Authors: Lee KJ, Soyer HP Abstract Keratinocyte cancers are the most common malignancy among people with European ancestry, and are very common on sun-exposed areas of the head and neck. Incidence is
- Two New Surgical Techniques to Refine Surgery Around the Ear: "The Inviscision" and the External Auditory Meatus Suture.Related ArticlesTwo New Surgical Techniques to Refine Surgery Around the Ear: "The Inviscision" and the External Auditory Meatus Suture. J Oral Maxillofac Surg. 2019 Sep 11;: Authors: Davies ROHL, Cascarini L, Coombes D, Warburton G PMID: 31585063 [PubMed - as supplied by publisher]
- Factors predicting for patient refusal of head and neck cancer therapy.Related ArticlesFactors predicting for patient refusal of head and neck cancer therapy. Head Neck. 2019 Oct 04;: Authors: Amini A, Verma V, Li R, Vora N, Kang R, Gernon TJ, Chang S, Karam S, Massarelli E, Maghami EG, Glaser S Abstract BACKGROUND: The purpose of this study was to evaluate the national rate of treatment refusal in head and neck cancer (HNC). METHODS: The National Cancer Databa
- Understanding the natural history of papillary thyroid cancer: Case series.Related ArticlesUnderstanding the natural history of papillary thyroid cancer: Case series. Head Neck. 2019 Oct 04;: Authors: Lin JK, Sakoda LC, Darbinian J, Chiao W, Calixto N, Gurushanthaiah D, Wang KH, Durr M Abstract BACKGROUND: Papillary thyroid cancer (PTC) incidence continues to rise. We describe the natural history of untreated PTC patients. METHODS: Retrospective case series of 31 u
- Long-term outcomes and toxicities of carbon-ion radiotherapy in malignant tumors of the sphenoid sinus.Related ArticlesLong-term outcomes and toxicities of carbon-ion radiotherapy in malignant tumors of the sphenoid sinus. Head Neck. 2019 Oct 04;: Authors: Hagiwara Y, Koto M, Bhattacharyya T, Hayashi K, Ikawa H, Nemoto K, Tsuji H Abstract BACKGROUND: Most of the primary sphenoid sinus tumors present with locally advanced stages with involvement of adjacent critical structures and are not amenable to r
- Dipeptidyl Peptidase-4 Inhibitor Treatment Could Decrease Chronic Rhinosinusitis in Diabetic Patients.Related ArticlesDipeptidyl Peptidase-4 Inhibitor Treatment Could Decrease Chronic Rhinosinusitis in Diabetic Patients. QJM. 2019 Oct 04;: Authors: Li SY, Chen HH, Lai CC, Lin CL, Kao CH Abstract AIM: To evaluate the relationship between dipeptidyl peptidase-4 inhibitor (DPP4i) treatment and chronic rhinosinusitis (CRS) in diabetic patients. METHOD: We used the Longitudinal Health Insurance D
- Lymphangioma in the Buccal Mucosa.Related ArticlesLymphangioma in the Buccal Mucosa. J Craniofac Surg. 2019 Oct 03;: Authors: Yalçin M, Laçin N Abstract Lymphangiomas are benign hamartomatous tumors which are characterized by abnormal proliferation of lymphatic vessels. They are lymphatic malformations which are commonly localized to head and neck region. They are rare located in the oral cavity and tongue, lips, buccal mucosa, soft
- Open Mastoid Cavity Obliteration With a High-Porosity Hydroxyapatite Ceramic Leads to High Rate of Revision Surgery and Insufficient Cavity Obliteration.Related ArticlesOpen Mastoid Cavity Obliteration With a High-Porosity Hydroxyapatite Ceramic Leads to High Rate of Revision Surgery and Insufficient Cavity Obliteration. Otol Neurotol. 2019 Oct 03;: Authors: Weiss NM, Stecher S, Bächinger D, Schuldt T, Langner S, Zonnur S, Mlynski R, Schraven SP Abstract OBJECTIVE: To assess long-term results and present experience with a high-porosity hydroxyapatite
- Fit-For-Purpose PD-L1 Biomarker Testing For Patient Selection in Immuno-Oncology: Guidelines For Clinical Laboratories From the Canadian Association of Pathologists-Association Canadienne Des Pathologistes (CAP-ACP).Related ArticlesFit-For-Purpose PD-L1 Biomarker Testing For Patient Selection in Immuno-Oncology: Guidelines For Clinical Laboratories From the Canadian Association of Pathologists-Association Canadienne Des Pathologistes (CAP-ACP). Appl Immunohistochem Mol Morphol. 2019 Oct 03;: Authors: Cheung CC, Barnes P, Bigras G, Boerner S, Butany J, Calabrese F, Couture C, Deschenes J, El-Zimaity H, Fischer G, Fiset PO, Garratt
- Prediction and analysis of Hub Genes in Renal Cell Carcinoma based on CFS Gene selection method combined with Adaboost algorithm.Related ArticlesPrediction and analysis of Hub Genes in Renal Cell Carcinoma based on CFS Gene selection method combined with Adaboost algorithm. Med Chem. 2019 Oct 03;: Authors: Wang Y, Zheng B, Xu M, Cai S, Younseo J, Zhang C, Jiang B Abstract BACKGROUND: Renal cell carcinoma (RCC) is the most common malignant tumor of the adult kidney. OBJECTIVE: The aim of this study was to identify key
- The Oticon Medical Neuro Zti cochlear implant and the Neuro 2 sound processor: multicentric evaluation of outcomes in adults and children.Related ArticlesThe Oticon Medical Neuro Zti cochlear implant and the Neuro 2 sound processor: multicentric evaluation of outcomes in adults and children. Int J Audiol. 2019 Oct 04;:1-8 Authors: Franco-Vidal V, Parietti-Winkler C, Guevara N, Truy E, Loundon N, Bailleux S, Ardoint M, Saaï S, Hoen M, Laplante-Lévesque A, Mosnier I, Bordure P, Vincent C Abstract Objective: This study evaluated the outco
- Latency of tobacco smoking for head and neck cancer among HPV-positive and HPV-negative individuals.Related ArticlesLatency of tobacco smoking for head and neck cancer among HPV-positive and HPV-negative individuals. Int J Cancer. 2019 Oct 04;: Authors: Madathil S, Rousseau MC, Joseph L, Coutlée F, Schlecht NF, Franco E, Nicolau B Abstract Human papillomavirus (HPV) infection and tobacco smoking are well known risk factors for head and neck cancers (HNC). Although an effect modification between ora
- Neutrophils are Underrecognized Contributors to Inflammatory Burden and Quality of Life in Chronic Rhinosinusitis.Related ArticlesNeutrophils are Underrecognized Contributors to Inflammatory Burden and Quality of Life in Chronic Rhinosinusitis. Allergy. 2019 Oct 04;: Authors: Succar EF, Li P, Ely KA, Chowdhury NI, Chandra RK, Turner JH PMID: 31583712 [PubMed - as supplied by publisher]
- Comparison of the 7th and 8th edition AJCC classification system in oral cavity squamous cell cancers.Related ArticlesComparison of the 7th and 8th edition AJCC classification system in oral cavity squamous cell cancers. Int J Cancer. 2019 Oct 03;: Authors: Singhavi HR, Chakrabarti S, Singh A, Mair M, Bhattacharjee A, Shetty R, Qayyumi B, Pai A, Joshi P, Nair D, Nair S, Chaturvedi P Abstract The aim of our study was to evaluate the predictive ability of the AJCC 8th edition staging system for oral ca
- Sentinel Node Biopsy in 105 High-Risk Cutaneous SCCs of the Head and Neck: Results of a Multicenter Prospective Study.Related ArticlesSentinel Node Biopsy in 105 High-Risk Cutaneous SCCs of the Head and Neck: Results of a Multicenter Prospective Study. Ann Surg Oncol. 2019 Oct 03;: Authors: Mooney CP, Martin RCW, Dirven R, Ashford BG, Shannon K, Palme CE, Ngo Q, Wykes J, Davies S, Gao K, Ch'ng S, Low TH, Gupta R, Clark JR Abstract BACKGROUND: Regional nodal metastases from cutaneous squamous cell carcinoma (cSCC) is
- Elective neck dissection in adenoid cystic carcinoma of head and neck: yes or no? A systematic review.Related ArticlesElective neck dissection in adenoid cystic carcinoma of head and neck: yes or no? A systematic review. Eur Arch Otorhinolaryngol. 2019 Oct 03;: Authors: Luksic I, Suton P Abstract PURPOSE: Adenoid cystic carcinoma of head and neck (AdCCHN) is salivary gland malignancy known for its slow progression accompanied with perineural invasion, rare lymphatic spread to the neck, high rate of l
- Single-cycle induction chemotherapy before chemoradiotherapy or surgery in functionally inoperable head and neck squamous cell carcinoma: 10-year results.Related ArticlesSingle-cycle induction chemotherapy before chemoradiotherapy or surgery in functionally inoperable head and neck squamous cell carcinoma: 10-year results. Eur Arch Otorhinolaryngol. 2019 Oct 03;: Authors: Breheret M, Lubgan D, Haderlein M, Hecht M, Traxdorf M, Schmidt D, Müller S, Kitzsteiner C, Kuwert T, Iro H, Fietkau R, Semrau S Abstract INTRODUCTION: The response to induction chem
- Risk of second primary malignancies in head and neck cancer patients treated with definitive radiotherapy.Related ArticlesRisk of second primary malignancies in head and neck cancer patients treated with definitive radiotherapy. NPJ Precis Oncol. 2019;3:22 Authors: Ng SP, Pollard C, Kamal M, Ayoub Z, Garden AS, Bahig H, Gunn GB, Frank SJ, Skinner HD, Phan J, Berends J, Morrison WH, Johnson JM, Ferrarotto R, Sturgis EM, Mohamed ASR, Lai SY, Fuller CD, Rosenthal DI Abstract Second primary malignancy (SPM)
- High Cervical Intrathecal Targeted Drug Delivery: A Case Report of Refractory Oropharyngeal Cancer Pain.Related ArticlesHigh Cervical Intrathecal Targeted Drug Delivery: A Case Report of Refractory Oropharyngeal Cancer Pain. Case Rep Oncol Med. 2019;2019:2098921 Authors: Moman RN, Rogers JM, Pittelkow TP Abstract Introduction: Some patients with head and neck cancers have pain refractory to aggressive multimodal therapies. Herein, we report the use of an intrathecal targeted drug delivery (TDD) system
- Nodal Merkel Cell Carcinoma in Head and Neck Lesions with an Unknown Primary: A Case Report in Light of the Literature.Related ArticlesNodal Merkel Cell Carcinoma in Head and Neck Lesions with an Unknown Primary: A Case Report in Light of the Literature. Yonago Acta Med. 2019 Sep;62(3):258-262 Authors: Ikeda R, Ohta N, Fukaya S, Shoji F, Suzuki T, Noguchi N, Kakuta R, Hayashi K, Kiba T, Murakami K, Nakamura Y Abstract Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine skin cancer. To diagnose nodal M
- Successful Surgical Treatment for Dysphagia Secondary to Descending Necrotizing Mediastinitis.Related ArticlesSuccessful Surgical Treatment for Dysphagia Secondary to Descending Necrotizing Mediastinitis. Yonago Acta Med. 2019 Sep;62(3):253-257 Authors: Fujiwara K, Koyama S, Fukuhara T, Takeuchi H Abstract Descending necrotizing mediastinitis (DNM) is a life-threatening disease with a high fatality rate that occurs as a complication of deep neck abscess. DNM complicated by severe dysphagia du
- Correlation between Auditory Spectral Resolution and Speech Perception in Children with Cochlear Implants.Related ArticlesCorrelation between Auditory Spectral Resolution and Speech Perception in Children with Cochlear Implants. Iran J Med Sci. 2019 Sep;44(5):382-389 Authors: Jeddi Z, Lotfi Y, Moossavi A, Bakhshi E, Hashemi SB Abstract Background: Variability in speech performance is a major concern for children with cochlear implants (CIs). Spectral resolution is an important acoustic component in speec
- High-resolution Imaging of the Human Cochlea through the Round Window by means of Optical Coherence Tomography.Related ArticlesHigh-resolution Imaging of the Human Cochlea through the Round Window by means of Optical Coherence Tomography. Sci Rep. 2019 Oct 03;9(1):14271 Authors: Starovoyt A, Putzeys T, Wouters J, Verhaert N Abstract The human cochlea is deeply embedded in the temporal bone and surrounded by a thick otic capsule, rendering its internal structure inaccessible for direct visualization. Clinical
- Cyst of the right lymphatic duct.Related ArticlesCyst of the right lymphatic duct. Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Sep 30;: Authors: Stárek I, Salzman R, Pokorná Z, Skanderová D Abstract INTRODUCTION: Cysts originating from cervical lymphatic ducts are very rare affections. However, they play an important role in the differential diagnosis of supraclavicular masses. The aetiology remains unclear. Practically all cases a
- Acoustic Voice Quality Index as a Potential Tool for Voice Screening.Related ArticlesAcoustic Voice Quality Index as a Potential Tool for Voice Screening. J Voice. 2019 Sep 30;: Authors: Faham M, Laukkanen AM, Ikävalko T, Rantala L, Geneid A, Holmqvist-Jämsén S, Ruusuvirta K, Pirilä S Abstract INTRODUCTION: To diminish the risk of voice disorders in people who are highly dependent on their voices, such as teachers, vocal screening is important already at the beginning
- Surgery in the context of kinase inhibitor therapy for locally invasive thyroid cancer.Related ArticlesSurgery in the context of kinase inhibitor therapy for locally invasive thyroid cancer. Eur J Surg Oncol. 2019 Sep 25;: Authors: Hartl DM, Guerlain J, Bresuskin I, Baudin E, Lamartina L, Hadoux J, Leboulleux S, Schlumberger M Abstract Kinase inhibitors (KI) for advanced and aggressive forms of differentiated, medullary and anaplastic thyroid carcinoma have been shown to provide signif
- Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.Related ArticlesEnergy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes. Surgery. 2019 Sep 30;: Authors: Hughes DT, Reyes-Gastelum D, Kovatch KJ, Hamilton AS, Ward KC, Haymart MR Abstract INTRODUCTION: The relationship between treatment for differentiated thyroid cancer and patient-report of decreased energy and fatigue remains unclear.
- Real-world treatment patterns, cost of care and effectiveness of therapies for patients with squamous cell carcinoma of head and neck pre and post approval of immuno-oncology agents.Related ArticlesReal-world treatment patterns, cost of care and effectiveness of therapies for patients with squamous cell carcinoma of head and neck pre and post approval of immuno-oncology agents. J Med Econ. 2019 Oct 04;:1 Authors: Abraham P, Kish JK, Korytowsky B, Radtchenko J, Singh P, Shaw J, Feinberg B Abstract Aims: In 2016 nivolumab and pembrolizumab were approved for the treatment of squamo
- Implication and Management of Incidental Oropharyngeal Papillomas-A Retrospective Case Series Review.Related ArticlesImplication and Management of Incidental Oropharyngeal Papillomas-A Retrospective Case Series Review. Ear Nose Throat J. 2019 Oct 03;:145561319871228 Authors: Kim D, Siegel J, Chouake RJ, Geliebter J, Zalvan CH Abstract INTRODUCTION: Incidental papillomas of the pharynx can be found while examining the nasopharynx, oropharynx, and hypopharynx for other disorders of the head and neck.
- Differential Diagnosis Under the Microscope: Crystalloid Granuloma of the Parotid Gland.Related ArticlesDifferential Diagnosis Under the Microscope: Crystalloid Granuloma of the Parotid Gland. Ear Nose Throat J. 2019 Oct 03;:145561319871239 Authors: O'Malley QF, Sims JR, Spaulding SL, Sandler ML, Everest S, Khorsandi AS, Brandwein-Weber M, Urken ML PMID: 31581833 [PubMed - as supplied by publisher]
- Moth in the Left Ear.Related ArticlesMoth in the Left Ear. Ear Nose Throat J. 2019 Oct 03;:145561319872170 Authors: Chiu CC, She YY PMID: 31581832 [PubMed - as supplied by publisher]
- Huge Cholesterol Granuloma in Nasoseptal Region.Related ArticlesHuge Cholesterol Granuloma in Nasoseptal Region. Ear Nose Throat J. 2019 Oct 03;:145561319870486 Authors: Yücel Ekici N PMID: 31581831 [PubMed - as supplied by publisher]
- Mastoid Reconstruction With Platelet-Rich Plasma and Bone Pate After Canal Wall Down Mastoidectomy: A Preliminary Report.Related ArticlesMastoid Reconstruction With Platelet-Rich Plasma and Bone Pate After Canal Wall Down Mastoidectomy: A Preliminary Report. Ear Nose Throat J. 2019 Oct 03;:145561319879789 Authors: Askar SM, Saber IM, Omar M Abstract OBJECTIVES: Mastoid reconstruction principle had been described to overcome problems of chronic discharging cavity. Different materials were used; nonbiologic materials see
- Evaluation of the Presence of Sensorineural Hearing Loss and the Relationship With Intraoperative Findings in Cholesteatoma.Related ArticlesEvaluation of the Presence of Sensorineural Hearing Loss and the Relationship With Intraoperative Findings in Cholesteatoma. Ear Nose Throat J. 2019 Oct 03;:145561319877763 Authors: Gulustan F, Yazici ZM, Sayin I, Abakay MA, Gunes S, Akidil AO Abstract We investigated whether cholesteatoma is associated with sensorineural hearing loss (SNHL) and the effects of a lateral semicircular c
- Benign Paroxysmal Positional Vertigo: Comparison of Idiopathic BPPV and BPPV Secondary to Vestibular Neuritis.Related ArticlesBenign Paroxysmal Positional Vertigo: Comparison of Idiopathic BPPV and BPPV Secondary to Vestibular Neuritis. Ear Nose Throat J. 2019 Oct 03;:145561319871234 Authors: Türk B, Akpinar M, Kaya KS, Korkut AY, Turgut S Abstract The aim of this study was to reveal clinical features of benign paroxysmal positional vertigo (BPPV) through comparing idiopathic BPPV and BPPV secondary to vesti
- Investigation of Oxidative Stress in Antrochoanal Polyp Etiology.Related ArticlesInvestigation of Oxidative Stress in Antrochoanal Polyp Etiology. Ear Nose Throat J. 2019 Oct 03;:145561319871036 Authors: Islamoglu Y, Kesici GG, Canan Y, Kale H, Kara Ö, Erel O, Babademez MA Abstract Antrochoanal polyps (ACPs) are benign lesions of the paranasal sinuses. Similarities between ACPs and nasal polyps have been previously investigated. However, oxidative stress has been
- The Role of the Parotid-Mastoid Fascia in Identification of the Facial Nerve Trunk During Parotidectomy.Related ArticlesThe Role of the Parotid-Mastoid Fascia in Identification of the Facial Nerve Trunk During Parotidectomy. Ear Nose Throat J. 2019 Oct 03;:145561319877998 Authors: Micucci SB, Cheng SS, Song T, Rasgon B Abstract OBJECTIVE: We aim to describe the parotid fascia as a landmark that can help identify the immediately underlying facial nerve trunk. METHODS: Dissection of the parotid
- Overstay and Readmission in Ear, Nose, and Throat Day Surgery-Factors Affecting Postanesthesia Course.Related ArticlesOverstay and Readmission in Ear, Nose, and Throat Day Surgery-Factors Affecting Postanesthesia Course. Ear Nose Throat J. 2019 Oct 03;:145561319872165 Authors: Tolvi M, Lehtonen L, Tuominen-Salo H, Paavola M, Mattila K, Aaltonen LM Abstract AIMS: Many procedures in ear, nose, and throat (ENT) day surgery are carried out under local anesthesia in Finland, whereas many other countries u
- Genetic Epidemiology and Clinical Features of Hereditary Hearing Impairment in the Taiwanese Population.Related ArticlesGenetic Epidemiology and Clinical Features of Hereditary Hearing Impairment in the Taiwanese Population. Genes (Basel). 2019 Oct 01;10(10): Authors: Wu CC, Tsai CY, Lin YH, Chen PY, Lin PH, Cheng YF, Wu CM, Lin YH, Lee CY, Erdenechuluun J, Liu TC, Chen PL, Hsu CJ Abstract Hereditary hearing impairment (HHI) is a common but heterogeneous clinical entity caused by mutations in a plethor
- Antitumor Efficacy of Liposome-Encapsulated NVP-BEZ235 Combined with Irreversible Electroporation for Head and Neck Cancer.Related ArticlesAntitumor Efficacy of Liposome-Encapsulated NVP-BEZ235 Combined with Irreversible Electroporation for Head and Neck Cancer. Molecules. 2019 Oct 01;24(19): Authors: Tian L, Wang L, Qiao Y, Lu L, Lee P, Chang A, Ravi S, Rogers TA, Melancon MP Abstract Irreversible electroporation (IRE) kills tumor cells by the delivery of short pulses of strong electric fields. However, the field streng
- Associative responses to visual shape stimuli in the mouse auditory cortex.Related ArticlesAssociative responses to visual shape stimuli in the mouse auditory cortex. PLoS One. 2019;14(10):e0223242 Authors: Ogi M, Yamagishi T, Tsukano H, Nishio N, Hishida R, Takahashi K, Horii A, Shibuki K Abstract Humans can recall various aspects of a characteristic sound as a whole when they see a visual shape stimulus that has been intimately associated with the sound. In subjects with
- Classification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis.Related ArticlesClassification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis. PLoS One. 2019;14(10):e0223137 Authors: Manis PB, Kasten MR, Xie R Abstract The cochlear nucleus (CN) transforms the spike trains of spiral ganglion cells into a set of sensory representations that are essential for auditory discriminations and perception. These transformations require the coo
- Selection of Head and Neck Cancer Patients for Intensive Therapy.Related ArticlesSelection of Head and Neck Cancer Patients for Intensive Therapy. Int J Radiat Oncol Biol Phys. 2019 Sep 30;: Authors: Vitzthum LK, Park H, Zakeri K, Bryant AK, Feng C, Shen H, Cohen EEW, Murphy JD, Mell LK Abstract PURPOSE: Previous studies have found that head and neck cancer (HNC) patients with a higher relative hazard for recurrence vs. competing mortality (ω+ ratio) are more like
- Estimating PTV margins in head and neck stereotactic ablative radiation therapy (SABR) through target site analysis of positioning and intrafractional accuracy.Related ArticlesEstimating PTV margins in head and neck stereotactic ablative radiation therapy (SABR) through target site analysis of positioning and intrafractional accuracy. Int J Radiat Oncol Biol Phys. 2019 Sep 30;: Authors: Mesko S, Wang H, Tung S, Wang C, Pasalic D, Chapman BV, Moreno AC, Reddy JP, Garden AS, Rosenthal DI, Gunn GB, Frank SJ, Fuller CD, Morrison W, Phan J Abstract PURPOSE/OBJEC
- A distinct pre-treatment immune gene signature in lentigo maligna is associated with imiquimod response.Related ArticlesA distinct pre-treatment immune gene signature in lentigo maligna is associated with imiquimod response. J Invest Dermatol. 2019 Sep 30;: Authors: Halse H, Caramia F, McLean CA, Wang M, Aw Yeang HX, Keam SP, Behren A, Ly L, Haskett M, Cebon J, McArthur GA, Neeson PJ, Mar VJ Abstract Lentigo Maligna (LM) is a common subtype of in-situ melanoma on chronically sun-exposed skin, particula
- An Exploratory Step Toward Measuring the 'Meaning of Life' in Patients with Tinnitus and in Cochlear Implant Users.Related ArticlesAn Exploratory Step Toward Measuring the 'Meaning of Life' in Patients with Tinnitus and in Cochlear Implant Users. J Am Acad Audiol. 2019 Sep 27;: Authors: Tyler R, Perreau A, Mohr AM, Ji H, Mancini PC Abstract BACKGROUND: Many questionnaires attempt to quantify the "quality of life." However, we believe understanding the quality of life is complex, and many widely used questionnaire
- Application of Digital Remote Wireless Microphone Technology in Single-Sided Deaf Cochlear Implant Recipients.Related ArticlesApplication of Digital Remote Wireless Microphone Technology in Single-Sided Deaf Cochlear Implant Recipients. J Am Acad Audiol. 2019 Sep 13;: Authors: Wesarg T, Stelzig Y, Hilgert-Becker D, Kathage B, Wiebe K, Aschendorff A, Arndt S, Speck I Abstract BACKGROUND: Previous research showed benefits of remote wireless technology in bilaterally moderate-to-severe hearing-impaired particip
- High- and Low-Performing Adult Cochlear Implant Users on High-Variability Sentence Recognition: Differences in Auditory Spectral Resolution and Neurocognitive Functioning.Related ArticlesHigh- and Low-Performing Adult Cochlear Implant Users on High-Variability Sentence Recognition: Differences in Auditory Spectral Resolution and Neurocognitive Functioning. J Am Acad Audiol. 2019 Sep 30;: Authors: Tamati TN, Ray C, Vasil KJ, Pisoni DB, Moberly AC Abstract BACKGROUND: Postlingually deafened adult cochlear implant (CI) users routinely display large individual differences
- Trends in thyroid carcinoma among thyroidectomy patients: a 12-year multicenter study.Related ArticlesTrends in thyroid carcinoma among thyroidectomy patients: a 12-year multicenter study. Ann Saudi Med. 2019 Sep-Oct;39(5):345-349 Authors: Doubi A, Al-Qannass A, Al-Angari SS, Al-Qahtani KH, Alessa M, Al-Dhahri S Abstract BACKGROUND: Thyroid malignancy, the most diagnosed cancer of the endocrine system, represents 2% of all malignancies worldwide. The increasing incidence of thyroid ca
- A contemporary analysis of racial disparities in recommended and received treatment for head and neck cancer.Related ArticlesA contemporary analysis of racial disparities in recommended and received treatment for head and neck cancer. Cancer. 2019 Oct 03;: Authors: Nocon CC, Ajmani GS, Bhayani MK Abstract BACKGROUND: Racial disparities in squamous cell carcinoma of the head and neck (HNSCC) negatively affect non-Hispanic black (NHB) patients. This study was aimed at understanding how treatment is prescribed
- Reducing Head and Neck UV Exposure in Younger Persons-Millennials, Wear a Hat (or Grow Your Hair Longer).Related ArticlesReducing Head and Neck UV Exposure in Younger Persons-Millennials, Wear a Hat (or Grow Your Hair Longer). JAMA Otolaryngol Head Neck Surg. 2019 Oct 03;: Authors: Hall ET, Paulson KG PMID: 31580410 [PubMed - as supplied by publisher]
- Between Current Implications and Future Perspectives-Reply.Related ArticlesBetween Current Implications and Future Perspectives-Reply. JAMA Otolaryngol Head Neck Surg. 2019 Oct 03;: Authors: Lieu JEC, Gantz J PMID: 31580396 [PubMed - as supplied by publisher]
- Head and Neck Melanoma Incidence Trends in the Pediatric, Adolescent, and Young Adult Population of the United States and Canada, 1995-2014.Related ArticlesHead and Neck Melanoma Incidence Trends in the Pediatric, Adolescent, and Young Adult Population of the United States and Canada, 1995-2014. JAMA Otolaryngol Head Neck Surg. 2019 Oct 03;: Authors: Bray HN, Simpson MC, Zahirsha ZS, Brinkmeier JV, Walen SG, Fosko SW, Osazuwa-Peters N Abstract Importance: Melanoma is one of the most common cancers worldwide, typically diagnosed in older
- Skull Base and Orbital Solitary Plasmacytoma Mimicking a Meningioma.Related ArticlesSkull Base and Orbital Solitary Plasmacytoma Mimicking a Meningioma. JAMA Otolaryngol Head Neck Surg. 2019 Oct 03;: Authors: Dang S, Manzoor NF, Harmsen H, Rivas A, Aulino JM PMID: 31580384 [PubMed - as supplied by publisher]
- Trigeminal nerve and white matter brain abnormalities in chronic orofacial pain disorders.Related ArticlesTrigeminal nerve and white matter brain abnormalities in chronic orofacial pain disorders. Pain Rep. 2019 Jul-Aug;4(4):e755 Authors: Moayedi M, Hodaie M Abstract The orofacial region is psychologically important, given that it serves fundamental and important biological purposes. Chronic orofacial pain disorders affect the head and neck region. Although some have clear peripheral etio
- Papillary Thyroid Carcinoma Coexistent with Oral Squamous Cell Carcinoma: A Case Report and Review of Literature.Related ArticlesPapillary Thyroid Carcinoma Coexistent with Oral Squamous Cell Carcinoma: A Case Report and Review of Literature. J Dent (Shiraz). 2019 Sep;20(3):215-219 Authors: Jaafari-Ashkavandi Z, Danesteh H, Keshvari H Abstract Multiple primary tumors may develop in patients with head and neck squamous cell carcinoma. The coincidence of head and neck squamous cell carcinoma with papillary thyroi
- Hemiarthroplasty for Femoral Neck Fracture.Related ArticlesHemiarthroplasty for Femoral Neck Fracture. JBJS Essent Surg Tech. 2019 Jun 26;9(2):e13 Authors: Rodriguez-Buitrago A, Attum B, Cereijo C, Yusi K, Jahangir AA, Obremskey WT Abstract Hemiarthroplasty is a common treatment for femoral neck fractures in the elderly population. The main complications are periprosthetic dislocation and infection, which potentially impact morbidity and qual
- Integrin α-5 as a potential biomarker of head and neck squamous cell carcinoma.Related ArticlesIntegrin α-5 as a potential biomarker of head and neck squamous cell carcinoma. Oncol Lett. 2019 Oct;18(4):4048-4055 Authors: Zou B, Wang D, Xu K, Yuan DY, Meng Z, Zhang B Abstract Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors that endanger human health. In recent years, the incidence of HNSCC has been increasing, without any significant impr
- Concurrent chemoradiotherapy with intravenous cisplatin and docetaxel for advanced oral cancer.Related ArticlesConcurrent chemoradiotherapy with intravenous cisplatin and docetaxel for advanced oral cancer. Nagoya J Med Sci. 2019 Aug;81(3):407-414 Authors: Sato K, Hayashi Y, Watanabe K, Yoshimi R, Hibi H Abstract Concurrent chemoradiotherapy (CCRT) is a common treatment for advanced oral cancer, and its efficacy has been reported in many reviews. We have performed concurrent CCRT with intraven
- Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Giant Left Pectoral Muscle Plasmacytoma and Multiple Myeloma Case.Related ArticlesFluorine-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in a Giant Left Pectoral Muscle Plasmacytoma and Multiple Myeloma Case. Indian J Nucl Med. 2019 Oct-Dec;34(4):341-343 Authors: Martínez-Amador N, Quirce R, Martínez-Rodríguez I, Lucas-Velázquez B, Fernández-Martínez C, Banzo I Abstract Extramedullary plasmacytoma is an unusual manifestation in multiple mye
- The effect of YAP expression in tumor cells and tumor stroma on the prognosis of patients with squamous cell carcinoma of the oral cavity floor and oral surface of the tongue.Related ArticlesThe effect of YAP expression in tumor cells and tumor stroma on the prognosis of patients with squamous cell carcinoma of the oral cavity floor and oral surface of the tongue. Oncol Lett. 2019 Oct;18(4):3561-3570 Authors: Szelachowska J, Donizy P, Ratajczak-Wielgomas K, Halon A, Zielecka-Debska D, Lichon K, Maciejczyk A, Lata-Wozniak E, Piotrowska A, Matkowski R Abstract Classic progn
- [Potential of computer-assisted navigation systems in the surgical treatment of chronic sinusitis, nasal cavity and paranasal sinuses tumors].Related Articles[Potential of computer-assisted navigation systems in the surgical treatment of chronic sinusitis, nasal cavity and paranasal sinuses tumors]. Vestn Otorinolaringol. 2019;84(4):6-12 Authors: Karpischenko SA, Bolozneva EV, Bibik PR, Karpischenko ES Abstract PURPOSE: To describe the principles of medical navigation systems in head and neck surgery, the possibility of their application a
- A 3-miRNA signature predicts survival of patients with hypopharyngeal squamous cell carcinoma after post-operative radiotherapy.Related ArticlesA 3-miRNA signature predicts survival of patients with hypopharyngeal squamous cell carcinoma after post-operative radiotherapy. J Cell Mol Med. 2019 Oct 02;: Authors: Xu X, Lu Z, Gross N, Li G, Zhang F, Lei D, Pan X Abstract Since the prognosis of hypopharyngeal squamous cell carcinoma (HSCC) remains poor, identification of miRNA as a potential prognostic biomarker for HSCC may help
- Graft interposition for preventing Frey's syndrome in patients undergoing parotidectomy.Related ArticlesGraft interposition for preventing Frey's syndrome in patients undergoing parotidectomy. Cochrane Database Syst Rev. 2019 Oct 03;10:CD012323 Authors: Ye L, Cao Y, Yang W, Wu F, Lin J, Li L, Li C Abstract BACKGROUND: Frey's syndrome is characterised by transient flushing and sometimes facial sweating in the area of the auriculotemporal nerve. It most commonly occurs after parotidectomy
- Rational combination with PDK1 inhibition overcomes cetuximab resistance in head and neck squamous cell carcinoma.Related ArticlesRational combination with PDK1 inhibition overcomes cetuximab resistance in head and neck squamous cell carcinoma. JCI Insight. 2019 Oct 03;4(19): Authors: Lu H, Lu Y, Xie Y, Qiu S, Li X, Fan Z Abstract Cetuximab, an EGFR-blocking antibody, is currently approved for treatment of metastatic head and neck squamous cell carcinoma (HNSCC), but its response rate is limited. In addition to
- Hair bundle stimulation mode modifies manifestations of mechanotransduction adaptation.Related ArticlesHair bundle stimulation mode modifies manifestations of mechanotransduction adaptation. J Neurosci. 2019 Oct 02;: Authors: Caprara GA, Mecca AA, Wang Y, Ricci AJ, Peng AW Abstract Sound detection in auditory sensory hair cells depends on the deflection of the stereocilia hair bundle which opens mechano-electric transduction (MET) channels. Adaptation is hypothesized to be a critical p
- Variability of Sarcoid Skin Manifestations Is Illustrated in a Patient With Multiple Concurrent Pinna Lesions.Related ArticlesVariability of Sarcoid Skin Manifestations Is Illustrated in a Patient With Multiple Concurrent Pinna Lesions. Ear Nose Throat J. 2019 Oct 02;:145561319871227 Authors: Jones SE, Pollak N PMID: 31578109 [PubMed - as supplied by publisher]
- Irradiation-Induced Vocal Fold Paralysis: A Delayed Complication.Related ArticlesIrradiation-Induced Vocal Fold Paralysis: A Delayed Complication. Ear Nose Throat J. 2019 Oct 02;:145561319872164 Authors: Hamdan AL, Abou Rizk S, Ghanem A, El Natout T PMID: 31578105 [PubMed - as supplied by publisher]
- Role of α-Tocopherol Acetate on Nasal Respiratory Functions: Mucociliary Clearance and Rhinomanometric Evaluations in Primary Atrophic Rhinitis.Related ArticlesRole of α-Tocopherol Acetate on Nasal Respiratory Functions: Mucociliary Clearance and Rhinomanometric Evaluations in Primary Atrophic Rhinitis. Ear Nose Throat J. 2019 Oct 02;:145561319870483 Authors: Testa D, Marcuccio G, Lombardo N, Cocuzza SG, Guerra G, Motta G Abstract Primary atrophic rhinitis is a disease of the nose and of paranasalsinuses characterized by a progressive loss o
- Morphometry of the Digastric Ridge and Its Significance for Mastoid Surgeries-A Cadaveric Study.Related ArticlesMorphometry of the Digastric Ridge and Its Significance for Mastoid Surgeries-A Cadaveric Study. Ear Nose Throat J. 2019 Oct 02;:145561319870491 Authors: Irugu DVK, Singh A, Kumar R Abstract OBJECTIVE: Digastric ridge (DR) is an important landmark to locate facial nerve (FN) and sigmoid sinus for mastoid surgeries and transmastoid approaches. We aim to look for the effect of temporal
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