Related ArticlesAdvances and challenges in precision medicine in salivary gland cancer. Cancer Treat Rev. 2019 Oct 14;80:101906 Authors: Lassche G, van Boxtel W, Ligtenberg MJL, van Engen-van Grunsven ACH, van Herpen CML Abstract Salivary gland cancer (SGC) is a rare malignancy consisting of 22 subtypes with different genetic, histological and clinical characteristics. This rarity and heterogeneity makes systemic treatment of recurrent or metastatic...
Thu Oct 24, 2019 14:36
Related ArticlesParaneoplastic pemphigus: a clinical, laboratorial, and therapeutic overview. An Bras Dermatol. 2019;94(4):388-398 Authors: Maruta CW, Miyamoto D, Aoki V, Carvalho RGR, Cunha BM, Santi CG Abstract Paraneoplastic pemphigus is a rare and severe autoimmune blistering disease characterized by mucocutaneous lesions associated with benign and malignant neoplasms. Diagnostic criteria include the presence of chronic mucositis and polymorphic...
Thu Oct 24, 2019 14:36
Related ArticlesBCR-ABL1-like B-Acute Lymphoblastic Leukemia/Lymphoma: A Comprehensive Review. Arch Pathol Lab Med. 2019 Oct 23;: Authors: Jain S, Abraham A Abstract CONTEXT.—: In the 2016 update of the World Health Organization (WHO) classification of hematopoietic neoplasms, BCR-ABL1-like B-acute lymphoblastic leukemia/lymphoma (B-ALL) is added as a new provisional entity that lacks the BCR-ABL1 translocation but shows a pattern of gene expression...
Thu Oct 24, 2019 14:36
Related ArticlesIdentification of susceptibility gene mutations associated with the pathogenesis of familial nonmedullary thyroid cancer. Mol Genet Genomic Med. 2019 Oct 22;:e1015 Authors: Zhu J, Wu K, Lin Z, Bai S, Wu J, Li P, Xue H, Du J, Shen B, Wang H, Liu Y Abstract BACKGROUND: Familial nonmedullary thyroid cancer (FNMTC) accounts for approximately 3%-9% of all thyroid cancers; however, the mechanisms underlying FNMTC remain unclear. Environmental...
Thu Oct 24, 2019 13:26
Related ArticlesWarthin-like mucoepidermoid carcinoma of the parotid gland: a diagnostic and therapeutic dilemma. Autops Case Rep. 2019 Oct-Dec;9(4):e2019122 Authors: Balasubiramaniyan V, Sultania M, Sable M, Muduly D, Kar M Abstract Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland tumor. Although the parotid gland is the most common site of involvement, other major salivary glands and the minor salivary glands-most commonly...
Thu Oct 24, 2019 13:26
Related ArticlesOral carcinoma development after 23 years of renal transplantation. Autops Case Rep. 2019 Oct-Dec;9(4):e2019112 Authors: Faustino ISP, Fernandes DT, Santos-Silva A, Vargas PA, Lopes MA Abstract Renal transplant patients are treated with immunosuppressive drugs that decrease the effectiveness of the immune system, making them more prone to developing cancer. Skin and lip carcinomas are common malignancies encountered after transplantation,...
Thu Oct 24, 2019 13:26
Related ArticlesDesmoplastic fibroma of the mandible: a rare gnathic bone tumor with a review of the literature. Autops Case Rep. 2019 Oct-Dec;9(4):e2019091 Authors: Madakshira MG, Bal A, Verma RK Abstract Desmoplastic fibroma (DF) is a rare bone tumor, which is known to involve mostly the gnathic bones. In this setting, the clinical presentation is usually represented by a bulging tumor of the face. Radiologically, the tumor is usually characterized...
Thu Oct 24, 2019 13:26
Related ArticlesReadmission following inpatient stereotactic radiosurgery for brain tumors. J Radiosurg SBRT. 2019;6(2):101-119 Authors: Tang AM, Bakhsheshian J, Lin M, Jarvis CA, Yuan E, Buchanan IA, Ding L, Strickland BA, Chang E, Zada G, Mack WJ, Attenello FJ Abstract Background: Stereotactic radiosurgery (SRS) is indicated for a spectrum of brain tumors and is often an outpatient procedure, though severe disease may precipitate inpatient treatment....
Thu Oct 24, 2019 13:26
Related ArticlesAn Unusual Presentation and Aggressive Course of Metastatic Myoepithelial Carcinoma. J Clin Aesthet Dermatol. 2019 Sep;12(9):46-48 Authors: Zeitouni NC, Huang DD, Row D Abstract Myoepithelial carcinomas are rare tumors that make up 1 to 2 percent of all salivary gland neoplasms. We present a case of a 55-year-old man with myoepithelial carcinoma that developed into widespread cutaneous, lung, and brain metastases refractory to treatment,...
Thu Oct 24, 2019 13:26
Related ArticlesMultifocal epithelioid hemangioma of the metacarpal bones: A case report. Radiol Case Rep. 2019 Dec;14(12):1467-1472 Authors: Fairfax A, Dey CB, Shaves S Abstract Epithelioid hemangioma of bone is a rare, locally aggressive but benign vascular tumor that is now recognized as a distinct entity from other vascular neoplasms. It is often difficult to distinguish on imaging studies from other vascular tumors, including epithelioid hemangioendothelioma,...
Thu Oct 24, 2019 13:26
Related ArticlesMetaplastic thymoma: a distinctive thymic neoplasm characterized by YAP1-MAML2 gene fusions. Mod Pathol. 2019 Oct 22;: Authors: Vivero M, Davineni P, Nardi V, Chan JKC, Sholl LM Abstract Metaplastic thymomas are rare biphasic thymic tumors that are characteristically well-circumscribed, confined to the thymus, and follow a benign to indolent clinical course. Their relationship to other thymic neoplasms remains unclear, and their molecular...
Thu Oct 24, 2019 13:26
Related ArticlesInterval breast cancer is associated with other types of tumors. Nat Commun. 2019 Oct 22;10(1):4648 Authors: Grassmann F, He W, Eriksson M, Gabrielson M, Hall P, Czene K Abstract Breast cancer (BC) patients diagnosed between two screenings (interval cancers) are more likely than screen-detected patients to carry rare deleterious mutations in cancer genes potentially leading to increased risk for other non-breast cancer (non-BC) tumors....
Thu Oct 24, 2019 13:26
Related ArticlesAn unusual case of pediatric-type follicular lymphoma: A case report. Medicine (Baltimore). 2019 Oct;98(41):e17567 Authors: Zhang H, Sun S, Zhang B, Yang H Abstract RATIONALE: Pediatric-type follicular lymphoma (PTFL) is a rare neoplasm with features that differ from those of adult-type follicular lymphoma. Compared to patients with adult-type follicular lymphoma, PTFL patients often show an excellent response. Preoperative diagnosis...
Thu Oct 24, 2019 13:26
Related ArticlesA case report of pelviscopic resection of invasive hydatidiform mole. Medicine (Baltimore). 2019 Oct;98(41):e17565 Authors: Lee HJ, Kim YS Abstract RATIONALE: Invasive moles occur in the fertile period, with about 95% occurring after previous mole removal and the remaining 5% occurring after several other pregnancies. PATIENT CONCERNS: A 27-year-old patient developed a rare invasive mole two months after a missed abortion. ...
Thu Oct 24, 2019 13:26
Related ArticlesA Life Threatening Subglottic and Mediastinal Hemangioma in an Infant. J Craniofac Surg. 2019 Jul;30(5):e402-e404 Authors: Onder SS, Gergin O, Karabulut B Abstract Subglottic and mediastinal hemangioma are rare benign vascular tumors of childhood. They cause potentially life threatening condition which requires intervention. Several therapeutic options have been described in the literature with varying degrees of success and complications....
Thu Oct 24, 2019 13:26
Related ArticlesRare Intrasellar Arachnoid Cyst Distinguishing From Other Benign Cystic Lesions and its Surgical Strategies. J Craniofac Surg. 2019 Jul;30(5):e400-e402 Authors: Chen B, Miao Y, Hu Y, Liao Y, Tu M, Yang X, Qiu Y Abstract The study reported a case of an intrasellar arachnoid cyst with visual disturbances as the main symptom. Arachnoid cyst is a common intracranial benign space-occupying lesion, but rarely seen in intrasellar region with...
Thu Oct 24, 2019 13:26
Related ArticlesHydrocephalus Due to Idiopathic Fourth Ventricle Outflow Obstruction. J Craniofac Surg. 2019 Jul;30(5):e397-e400 Authors: Bai J, Yu Q, Sun X, Xiao H, Wang K, Sun F, Sui Q Abstract The fourth ventricle outlet obstruction (FVOO) is a rare but well-established cause of obstructive tetra-ventricular hydrocephalus, characterizing with dilatation or large cerebrospinal fluid collection of the foramina of Magendie and Luschka. In children,...
Thu Oct 24, 2019 13:26
Related ArticlesNon-medical prescribing of systemic anticancer therapy in a multidisciplinary team oncology clinic. Br J Nurs. 2019 Jun 13;28(11):715-720 Authors: Hand Née Davies PR Abstract The number of people diagnosed and living with cancer in the UK continues to rise, placing increasing demands on specialist cancer care services. The incidence and prevalence of neuroendocrine tumours (NETs) has increased. An NET remains a rare cancer requiring...
Thu Oct 24, 2019 13:26
Related ArticlesTracheomalacia as Complication of Stenting for Esophageal Injury After Transsternal Approach to High Thoracic Vertebral Metastasis. World Neurosurg. 2019 05;125:67-71 Authors: Chung KC, Lin CH, Tsai CL, Li YH, Liao CH Abstract BACKGROUND: Esophageal injury is a severe surgical complication of a transsternal approach to high thoracic vertebral metastasis, which can result in mediastinitis and life-threatening consequences. A covered stent...
Thu Oct 24, 2019 13:26
Related ArticlesPrimary Sellar Paraganglioma: Case Report with Literature Review and Immunohistochemistry Resource. World Neurosurg. 2019 05;125:32-36 Authors: Lyne SB, Polster SP, Fidai S, Pytel P, Yamini B Abstract BACKGROUND: Differential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Primary paraganglioma is seldom considered. We present a case of this unique pathology, review the relevant literature,...
Thu Oct 24, 2019 13:26
Related ArticlesClinical significance of cancer specific methylation of the CDO1 gene in small bowel cancer. PLoS One. 2019;14(1):e0211108 Authors: Kojima K, Nakamura T, Ooizumi Y, Igarashi K, Tanaka T, Yokoi K, Ishii S, Nishizawa N, Katoh H, Kosaka Y, Sato T, Watanabe M, Yamashita K Abstract Although small bowel cancer (SBC) is extremely rare, its prognosis is poor, and molecular mechanism of the SBC development remains unclear. The aim of our study...
Thu Oct 24, 2019 13:26
Related ArticlesLaryngeal reconstruction for recurrent desmoid tumor using three-dimensional modeling: A unique approach for a rare tumor. Laryngoscope. 2019 09;129(9):1989-1992 Authors: Tracy LF, Patel SN, Buckmire RA, Shah RN Abstract Desmoid tumors are exceedingly rare within the larynx and cause significant morbidity due to their locally aggressive and infiltrative nature. Surgery is the mainstay of treatment with previous reports describing total...
Thu Oct 24, 2019 13:26
Related ArticlesEffects of craniopharyngioma cyst fluid on neurons and glial cells cultured from rat brain hypothalamus. J Chem Neuroanat. 2018 12;94:93-101 Authors: Ghosh M, Das S, Rao KVLN, Pruthi N, Ramesh VJ, Raju TR, Sathyaprabha TN Abstract Craniopharyngiomas (CPs) are rare, epithelial tumors of the central nervous system (CNS) that could lead to manifestation of multiple post-operative symptoms, ranging from hormonal imbalance to obesity, diabetes,...
Thu Oct 24, 2019 13:26
Related ArticlesDesmoid fibromatosis of the esophagogastric junction. Rev Esp Enferm Dig. 2018 10;110(10):677-678 Authors: DÃaz Ruiz R, Flores Fernández V, Pajares DÃaz JA Abstract Desmoid fibromatosis is a mesenchymal clonal proliferation, which lacks metastatic potential. Nevertheless, it has an infiltrative growth and thus implies a high morbidity1. Although the etiology remains unclear, mutations in the B-catenin or APC genes are involved. Some...
Thu Oct 24, 2019 13:26
Related ArticlesGermline mutation in the TP53 gene in uveal melanoma. Sci Rep. 2018 05 16;8(1):7618 Authors: Hajkova N, Hojny J, Nemejcova K, Dundr P, Ulrych J, Jirsova K, Glezgova J, Ticha I Abstract We performed comprehensive molecular analysis of five cases of metastasizing uveal malignant melanoma (UM) (fresh-frozen samples) with an NGS panel of 73 genes. A likely pathogenic germline TP53 mutation c.760Aâ>âG (p.I254V) was found in two tumor...
Thu Oct 24, 2019 13:26
Related ArticlesAtypical tuberous sclerosis complex presenting as familial renal cell carcinoma with leiomyomatous stroma. J Pathol Clin Res. 2018 07;4(3):167-174 Authors: Bah I, Fahiminiya S, Bégin LR, Hamel N, D'Agostino MD, Tanguay S, Foulkes WD Abstract We report an atypical tuberous sclerosis complex (TSC) phenotype presenting as familial multiple renal cell carcinomas (RCCs) with (angio)leiomyomatous stroma (RCCLS) (5/7 familial RCCs) on a background...
Thu Oct 24, 2019 13:26
Related ArticlesHigh Prevalence of Barrett's Esophagus and Esophageal Squamous Cell Carcinoma After Repair of Esophageal Atresia. Clin Gastroenterol Hepatol. 2018 04;16(4):513-521.e6 Authors: Vergouwe FWT, IJsselstijn H, Biermann K, Erler NS, Wijnen RMH, Bruno MJ, Spaander MCW Abstract BACKGROUND & AIMS: Esophageal atresia is rare, but improved surgical and intensive care techniques have increased rates of survival in children, so there are now...
Thu Oct 24, 2019 13:26
Related ArticlesResection of gliomas deemed inoperable by neurosurgeons based on preoperative imaging studies. J Neurosurg. 2018 09;129(3):567-575 Authors: Southwell DG, Birk HS, Han SJ, Li J, Sall JW, Berger MS Abstract OBJECTIVE Maximal safe resection is a primary objective in the management of gliomas. Despite this objective, surgeons and referring physicians may, on the basis of radiological studies alone, assume a glioma to be unresectable. Because...
Thu Oct 24, 2019 13:26
Related ArticlesEccrine spiradenoma mimicking a painful traumatic neuroma: case report. J Neurosurg. 2018 09;129(3):825-828 Authors: Donaldson K, Scott G, Cantor FK, Patronas NJ, Quezado M, Heiss JD Abstract Diagnosing and treating patients with persistent neuropathic pain associated with peripheral nerve lesions can be challenging. The authors report the rare case of a painful eccrine spiradenoma treated as a traumatic neuroma for many years because...
Thu Oct 24, 2019 13:26
Related ArticlesHeart combined with adrenal multiple pheochromocytomas. J Nucl Cardiol. 2018 06;25(3):1040-1043 Authors: Zhao SH, Liang S, Luo J, Mo HD, Jiang Y, Zhang MM, Yuan J Abstract Pheochromocytoma is a kind of rare tumor, occurring at any site in the sympathoadrenal system. Main lesions occur within the adrenal gland; only 1%-2% occur within the chest, and most of these are located in the posterior mediastinum. Intrapericardial pheochromocytoma...
Thu Oct 24, 2019 13:26
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract The platinum coordination complexes are a group of antineoplastic agents that are usually classified as alkylating agents, but which have distinctive features. Their anticancer activity appears to relate to the cross linking of DNA molecules in a fashion similar to standard alkylating agents. The DNA adducts formed by the platinum-containing complexes...
Thu Oct 24, 2019 14:36
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract Doxorubicin, epirubicin, idarubicin and valrubicin are structurally related cytotoxic antineoplastic antibiotics used in the therapy of several forms of lymphoma, leukemia, sarcoma and solid organ cancers. Doxorubicin is associated with a high rate of transient serum enzyme during therapy and to rare instances of clinically apparent acute liver injury...
Thu Oct 24, 2019 14:36
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract Carboplatin is an intravenously administered platinum coordination complex and alkylating agent which is used as a chemotherapeutic agent for the treatment of various cancers, mainly ovarian, head and neck and lung cancers. Carboplatin therapy is associated with a low rate of transient serum aminotransferase elevations and with rare instances of clinically...
Thu Oct 24, 2019 14:36
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract Bleomycin is a cystotoxic antibiotic that is used as an anticancer agent in the therapy of testicular and germ cell cancers, Hodgkin disease, lymphomas and tumors of the head and neck. Therapy with bleomycin in combination with other agents is often associated with mild-to-moderate serum enzyme elevations, but is a rare cause of clinically apparent liver...
Thu Oct 24, 2019 14:36
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