New England Journal of Medicine, Volume 381, Issue 17, Page 1603-1606, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1688-1690, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1675-1676, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1653-1662, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1663-1663, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1681-1683, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1693-1694, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1690-1693, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1606-1607, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1664-1673, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1684-1686, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1677-1678, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, October 2019.
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New England Journal of Medicine, Volume 381, Issue 17, Page 1686-1688, October 2019.
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New England Journal of Medicine, Ahead of Print.
Wed Oct 23, 2019 12:00
Rare diseases in aggregate affect approximately 30 million persons in the United States alone. Although next-generation sequencing is revolutionizing their diagnosis, the sheer number of distinct conditions (more than 7000 [https://globalgenes.org/rare-list]) and the limited number of patients…
Thu Oct 24, 2019 03:00
To the Editor: Public sharing of research data is being widely promoted. Medical image files contain "metadata" such as the name of the participant, the date of the scan, and the identification number. Such data are typically removed (deidentified) before data sharing, but images of the face in…
Thu Oct 24, 2019 03:00
The notion that the care delivered to seriously ill patients ought to promote those patients’ goals — regarding such matters as aggressiveness of treatment, hoped-for functional outcomes, and ability to participate in future events — is widely supported by patients, caregivers, clinicians, health…
Thu Oct 24, 2019 03:00
Hereditary thrombotic thrombocytopenic purpura (TTP), also known as Upshaw–Schulman syndrome (Online Mendelian Inheritance in Man number, 274150), is a rare autosomal recessive disorder caused by ADAMTS13 mutations that result in the absence or severe deficiency of the plasma metalloprotease…
Thu Oct 24, 2019 03:00
A 60-year-old woman who was a current smoker presented to the emergency department with acute chest pain. The troponin I level was 51 ng per liter on a high-sensitivity assay (reference value,
Thu Oct 24, 2019 03:00
A 77-year-old right-handed woman with limited cutaneous systemic sclerosis presented to the rheumatology clinic with a 2-year history of slowly progressive, painful swelling of her fingertips. On physical examination, the patient had telangiectases on her face and thorax and thickening of the skin…
Thu Oct 24, 2019 03:00
In 2018, knowing that I would become infected, I received a heart transplant from a donor with hepatitis C who’d died from a heroin overdose. Accepting a high-risk organ was a deliberate decision made long before I was offered the heart, and several factors figured heavily in my thought process.…
Thu Oct 24, 2019 03:00
Presentation of Case. Dr. Rachel Wood (Obstetrics and Gynecology): A 35-year-old pregnant woman was admitted to the labor and delivery unit of this hospital at 36 weeks 4 days of gestation for a planned repeat cesarean section because of placenta previa. At 6 weeks 4 days of gestation, the patient…
Thu Oct 24, 2019 03:00
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