Related ArticlesBaseline mucus cytokines predict 22-item Sino-Nasal Outcome Test results after endoscopic sinus surgery. Int Forum Allergy Rhinol. 2019 Oct 23;: Authors: Chowdhury NI, Li P, Chandra RK, Turner JH Abstract BACKGROUND: Mucus cytokines have been linked to baseline metrics of quality of life and olfactory function in patients with chronic rhinosinusitis (CRS). However, their potential utility in predicting postoperative outcomes has not been...
Thu Oct 24, 2019 14:47
Related ArticlesCurrent trends and 30-day surgical outcomes for thyroglossal duct cyst excision in children. Int J Pediatr Otorhinolaryngol. 2019 Oct 15;128:109725 Authors: Cheng J, Lerebours R, Lee HJ Abstract OBJECTIVE: Identify current trends, adverse events, and clinical predictors in children treated with thyroglossal duct cyst surgery. METHODS: Cross-sectional analysis using American College of Surgeons (ACS) National Surgical Quality...
Thu Oct 24, 2019 14:47
Related ArticlesModernizing the FDA's 510(k) Pathway. N Engl J Med. 2019 Oct 23;: Authors: Rathi VK, Ross JS PMID: 31644865 [PubMed - as supplied by publisher]
Thu Oct 24, 2019 14:47
Related ArticlesIncreased incidence of age-related macular degeneration in sensorineural hearing loss: A population-based cohort study. PLoS One. 2019;14(10):e0222919 Authors: Lee CY, Chen HC, Wu PH, Chi JC, Sun CC, Huang JY, Lin HY, Yang SF Abstract BACKGROUND: To evaluate the incidence of age-related macular degeneration (AMD) in patients diagnosed with sensorineural hearing loss (SNHL) via the application of the National Health Insurance Research...
Thu Oct 24, 2019 14:47
Related ArticlesUnderstanding the Dizziness Handicap Inventory (DHI): A Cross Sectional Analysis of Symptom Factors That Contribute to DHI Variance. Otol Neurotol. 2019 Oct 21;: Authors: Formeister EJ, Krauter R, Kirk L, Zhu TR, Rizk HG, Sharon JD Abstract OBJECTIVE: The Dizziness Handicap Inventory (DHI) is the most commonly used quality of life measure for vestibular disorders. However, there is wide variability in scores, and little is known about...
Thu Oct 24, 2019 14:47
Related ArticlesMulti-frequency Electrocochleography Measurements can be Used to Monitor and Optimize Electrode Placement During Cochlear Implant Surgery. Otol Neurotol. 2019 Oct 21;: Authors: Saoji AA, Patel NS, Carlson ML, Neff BA, Koka K, Tarigoppula VSA, Driscoll CLW Abstract OBJECTIVE: To report the use of multi-frequency intra-cochlear electrocochleography (ECOG) in monitoring and optimizing electrode placement during cochlear implant surgery....
Thu Oct 24, 2019 14:47
Related ArticlesNucleolin Mediates the Binding of Cancer Cells to L-selectin under Conditions of Lymphodynamic Shear Stress. Am J Physiol Cell Physiol. 2019 Oct 23;: Authors: Goldson TM, Turner KL, Huang Y, Carlson GE, Caggiano EG, Oberhauser AF, Fennewald SM, Burdick MM, Resto VA Abstract Head and neck squamous cell carcinoma (HNSCC) cells bind to lymphocytes via L-selectin in a shear-dependent manner. This interaction takes place exclusively under...
Thu Oct 24, 2019 14:47
Related ArticlesThe canonical Wnt pathway Postepy Biochem. 2019 10 01;65(3):183-192 Authors: Kleszcz R Abstract The canonical Wnt pathway is related to regulation of embryogenesis, cell differentiation and proliferation. Various proteins are necessary for proper signal transduction and β-catenin serves as the main mediator. In off-state of the Wnt pathway β-catenin undergoes proteasomal degradation, while in on-state increase of cytoplasmic concentration...
Thu Oct 24, 2019 14:47
Related ArticlesIncreased expression of estrogen receptor beta in idiopathic progressive subglottic stenosis. Laryngoscope. 2019 Oct 23;: Authors: Damrose EJ, Campbell RD, Darwish S, Erickson-DiRenzo E Abstract BACKGROUND/OBJECTIVES: Idiopathic progressive subglottic stenosis (IPSS) predominantly affects females in perimenopause. It has, therefore, been hypothesized that estrogen is involved in its pathogenesis. There are two main types of estrogen receptors:...
Thu Oct 24, 2019 14:47
Related ArticlesEffect of vocal fold implant placement on depth of vibration and vocal output. Laryngoscope. 2019 Oct 23;: Authors: Smith SL, Titze IR, Storck C, Mau T Abstract OBJECTIVE: Most type 1 thyroplasty implants and some common injectable materials are mechanically stiff. Placing them close to the supple vocal fold mucosa can potentially dampen vibration and adversely impact phonation, yet this effect has not been systematically investigated....
Thu Oct 24, 2019 14:47
Related ArticlesManagement of sporadic vestibular schwannoma with contralateral nonserviceable hearing. Laryngoscope. 2019 Oct 23;: Authors: Jia H, Nguyen Y, De Seta D, Hochet B, Smail M, Bernardeschi D, Wu H, Mosnier I, Kalamarides M, Sterkers O Abstract OBJECTIVES/HYPOTHESIS: To outline a possible decision-making process for sporadic vestibular schwannoma (VS) with contralateral nonserviceable hearing at diagnosis. STUDY DESIGN: Retrospective...
Thu Oct 24, 2019 14:47
Related ArticlesThe development and validation of the laryngopharyngeal measure of perceived sensation. Laryngoscope. 2019 Oct 23;: Authors: Melancon CC, Russell GB, Ruckart K, Persia S, Peterson M, Carter Wright S, Madden LL Abstract OBJECTIVES: Globus pharyngeus (GP) is described as the subjective sensation of having a "lump" in the throat in the absence of correlating physical findings or dysphagia. Historically, despite the frequency of patient complaints,...
Thu Oct 24, 2019 14:47
Related ArticlesOral recipient site infections in reconstructive surgery - impact of the graft itself and the perioperative antibiosis. Clin Oral Investig. 2019 Oct 23;: Authors: Zirk M, Zalesski A, Peters F, Kreppel M, Zinser M, Zöller JE Abstract OBJECTIVES: This study was designed to assess the influence of peri/post-operative antibiotic prophylaxis (POABP) and the reconstructive graft itself on recipient sites infections in head and neck surgery....
Thu Oct 24, 2019 14:47
Related ArticlesPredictors of changes in quality of life in head and neck cancer patients: a prospective study over a 6-month period. Eur Arch Otorhinolaryngol. 2019 Oct 23;: Authors: Roick J, Danker H, Dietz A, Papsdorf K, Singer S Abstract PURPOSE: Patients with head and neck cancer experience multiple complaints during treatment which also affect quality of life. The present study assessed predictors of temporal changes in quality of life over a 6-month...
Thu Oct 24, 2019 14:47
Related ArticlesStain-Free Resolution of Unmyelinated Axons in Transgenic Mice Using Fluorescence Microscopy. J Neuropathol Exp Neurol. 2019 Sep 23;: Authors: Mohan S, Coto Hernández I, Selig MK, Shibata S, Jowett N Abstract Though unmyelinated fibers predominate axon counts within peripheral nerves, they are frequently excluded in histomorphometric assessment as they cannot be readily resolved by light microscopy. Herein, we demonstrate stain-free resolution...
Thu Oct 24, 2019 14:47
Related ArticlesCurative effect of cold micro forceps and CO2 laser in the treatment of laryngeal amyloidosis. Acta Otolaryngol. 2019 Oct 23;:1-6 Authors: Wu X, Zhang J, Wei C Abstract Background: Amyloidosis is a benign, slowly progressive disease. However, the treatment of laryngeal amyloidosis (LA) has not been studied systematically. Objectives: To investigate the treatment results of cold micro forceps or carbon dioxide laser under microlaryngoscope...
Thu Oct 24, 2019 14:47
Related ArticlesHead and neck osteosarcoma: CT and MR imaging features. Dentomaxillofac Radiol. 2019 Oct 23;:20190202 Authors: Luo Z, Chen W, Shen X, Qin G, Yuan J, Hu B, Lyu J, Wen C, Xu W Abstract OBJECTIVE: This study aims to assess the CT and MRI features of head and neck osteosarcoma (HNO). METHODS: Thirty-seven HNOs were identified, and the following imaging characteristics were reviewed on CT and MRI. RESULTS: A total of 37 patients...
Thu Oct 24, 2019 14:47
Related ArticlesOral sarcomatoid squamous cell carcinoma: a retrospective study based on 14 cases. Histol Histopathol. 2019 Oct 23;:18176 Authors: Liu J, Xiao M, Wang Y Abstract The treatment outcomes for oral sarcomatoid squamous cell carcinoma (OSSCC) are far from satisfactory in our hospital. The aim of this study was to retrospectively summarize the OSSCC cases admitted to our department. From 2003 to 2017, 14 patients were hospitalized and diagnosed...
Thu Oct 24, 2019 14:47
Related ArticlesIdentification of susceptibility gene mutations associated with the pathogenesis of familial nonmedullary thyroid cancer. Mol Genet Genomic Med. 2019 Oct 22;:e1015 Authors: Zhu J, Wu K, Lin Z, Bai S, Wu J, Li P, Xue H, Du J, Shen B, Wang H, Liu Y Abstract BACKGROUND: Familial nonmedullary thyroid cancer (FNMTC) accounts for approximately 3%-9% of all thyroid cancers; however, the mechanisms underlying FNMTC remain unclear. Environmental...
Thu Oct 24, 2019 13:17
Related ArticlesRegulatory T cells induce CD4- NKT cell anergy and suppress NKT cell cytotoxic function. Cancer Immunol Immunother. 2019 Oct 22;: Authors: Ihara F, Sakurai D, Takami M, Kamata T, Kunii N, Yamasaki K, Iinuma T, Nakayama T, Motohashi S, Okamoto Y Abstract BACKGROUND: Due to the strong tumoricidal activities of activated natural killer T (NKT) cells, invariant NKT cell-based immunotherapy has shown promising clinical efficacy. However, suppressive...
Thu Oct 24, 2019 13:17
Related ArticlesNeurofibrosarcoma of the mandible derived from neurofibromatosis. Autops Case Rep. 2019 Oct-Dec;9(4):e2019094 Authors: Araujo JP, de Oliveira JX, Lanel V, Marcucci M Abstract Neurofibrosarcoma is a rare malignant neoplasm of the head and neck region and accounts for 8% to 16% of all cases. Its origin is varied and may stem from cells of the peripheral nerves, develop de novo, or result from malignant transformation of preexisting neurofibromas....
Thu Oct 24, 2019 13:17
Related ArticlesDose-response modeling the risk of carotid bleeding events after stereotactic body radiation therapy for previously irradiated head and neck cancer. J Radiosurg SBRT. 2019;6(2):83-89 Authors: Ling DC, Vargo JA, Gebhardt BJ, Grimm RJ, Clump DA, Ferris RL, Ohr JP, Heron DE Abstract Given the lack of clear dose constraints for the carotid artery, we created dose-response models to better quantify the risk of carotid bleeding events following...
Thu Oct 24, 2019 13:17
Human Papillomavirus and the use of nanoparticles for immunotherapy in HPV-related cancer: A review.
Related ArticlesHuman Papillomavirus and the use of nanoparticles for immunotherapy in HPV-related cancer: A review. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):544-550 Authors: Rupar MJ, Golusinski P, Golusinski W, Masternak MM Abstract Human Papillomavirus (HPV) remains one of the most commonly contracted sexually transmitted diseases around the world. There are a multitude of HPV types, some of which may never present any symptoms. Others, however,...
Thu Oct 24, 2019 13:17
Related ArticlesRole of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps. Mucosal Immunol. 2019 Oct 22;: Authors: Ogasawara N, Poposki JA, Klingler AI, Tan BK, Hulse KE, Stevens WW, Peters AT, Grammer LC, Welch KC, Smith SS, Conley DB, Raviv JR, Soroosh P, Takano KI, Himi T, Kern RC, Schleimer RP, Kato A Abstract Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by type 2...
Thu Oct 24, 2019 13:17
Related ArticlesHypofractionated radiotherapy for non-metastatic bone and soft tissue sarcomas. Cancer Radiother. 2019 Oct 19;: Authors: Yuce Sari S, Cengiz M, Dauletkazin A, Yazici G, Gultekin M, Hurmuz P, Yildiz F, Zorlu F, Gurkaynak M, Akyol F, Ozyigit G Abstract PURPOSE: To evaluate the efficacy and toxicity of hypofractionated radiotherapy in non-metastatic soft tissue and bone sarcomas. PATIENTS AND METHODS: Thirty patients underwent hypofractionated...
Thu Oct 24, 2019 13:17
Related ArticlesComparison of Cepstral Analysis Based on Voiced-Segment Extraction and Voice Tasks for Discriminating Dysphonic and Normophonic Korean Speakers. J Voice. 2019 Oct 19;: Authors: Kim GH, Bae IH, Park HJ, Lee YW Abstract OBJECTIVES: This study investigated whether there are differences in the discriminatory power of cepstral analysis according to the voiced-segment extraction method and voice tasks used for identifying dysphonic and normophonic...
Thu Oct 24, 2019 13:17
Related ArticlesPrognostic significance of albumin levels prior to treatment in patients with head and neck squamous cell carcinoma. Acta Otorrinolaringol Esp. 2019 Oct 19;: Authors: León X, Pardo L, Sansa A, Puig R, Serrano C, López M, Quer M, Valero C Abstract INTRODUCTION AND OBJECTIVES: Pre-treatment albumin levels have been shown to have prognostic capacity in oncological patients. The aim of this study is to analyse the relationship between albumin...
Thu Oct 24, 2019 13:17
Related ArticlesNew frontiers in proton therapy: applications in cancers. Cancer Commun (Lond). 2019 Oct 22;39(1):61 Authors: Yuan TZ, Zhan ZJ, Qian CN Abstract Proton therapy offers dominant advantages over photon therapy due to the unique depth-dose characteristics of proton, which can cause a dramatic reduction in normal tissue doses both distal and proximal to the tumor target volume. In turn, this feature may allow dose escalation to the tumor target...
Thu Oct 24, 2019 13:17
Related ArticlesA case report of severe nasal ischemia from cold agglutinin disease and a novel treatment protocol including HBOT. J Otolaryngol Head Neck Surg. 2019 Oct 22;48(1):52 Authors: Kohlert S, McLean L, Scarvelis D, Thompson C Abstract Cold agglutinin disease (CAD) is a rare condition leading to blood agglutination and autoimmune hemolytic anemia. Cutaneous ischemia resulting from CAD in the head and neck is uncommon. Treatment regimens and...
Thu Oct 24, 2019 13:17
Related ArticlesCorrection to: Advancing interdisciplinary research in head and neck cancer through a multicenter longitudinal prospective cohort study: the NETherlands QUality of life and BIomedical Cohort (NET-QUBIC) data warehouse and biobank. BMC Cancer. 2019 Oct 22;19(1):982 Authors: Verdonck-de Leeuw IM, Jansen F, Brakenhoff RH, Langendijk JA, Takes R, Terhaard CHJ, Baatenburg de Jong RJ, Smit JH, Leemans CR Abstract Following publication of the...
Thu Oct 24, 2019 13:17
Related ArticlesGenome rearrangements induce biofilm formation in Escherichia coli C - an old model organism with a new application in biofilm research. BMC Genomics. 2019 Oct 22;20(1):767 Authors: Król JE, Hall DC, Balashov S, Pastor S, Sibert J, McCaffrey J, Lang S, Ehrlich RL, Earl J, Mell JC, Xiao M, Ehrlich GD Abstract BACKGROUND: Escherichia coli C forms more robust biofilms than other laboratory strains. Biofilm formation and cell aggregation...
Thu Oct 24, 2019 13:17
Related ArticlesThe Impact of Medical Scribes on Patient Satisfaction in an Academic Otolaryngology Clinic. Ann Otol Rhinol Laryngol. 2019 Oct 22;:3489419884337 Authors: Keefe KR, Levi JR, Brook CD Abstract OBJECTIVES: Evidence shows that scribes can improve provider efficiency and satisfaction in several settings, but is mixed on whether scribes improve patient satisfaction. We studied whether scribes improved patient satisfaction in an academic otolaryngology...
Thu Oct 24, 2019 13:17
Related ArticlesYolk Sac Tumors of the Head and Neck in Aicardi Syndrome. Ann Otol Rhinol Laryngol. 2019 Oct 22;:3489419883660 Authors: Epperson MV, Born HL, Wang D, Myer CM Abstract OBJECTIVES: To understand that yolk sac tumors (YSTs) of the head and neck (H&N) are exceedingly rare and typically carry a poor prognosis. To acknowledge the possibility of increased incidence in patients with Aicardi Syndrome and the ramifications this has on early...
Thu Oct 24, 2019 13:17
Related ArticlesChanges in Cortical Auditory Evoked Potentials by Ipsilateral, Contralateral and Binaural Speech Stimulation in Normal-Hearing Adults. Clin Exp Otorhinolaryngol. 2019 Oct 24;: Authors: Lee JY, Kang BC, Park JW, Park HJ Abstract Objectives: Cortical auditory evoked potentials (CAEPs) have been used to examine auditory cortical development or changes in patients with hearing loss. However, there have been no studies analyzing CAEP responses...
Thu Oct 24, 2019 13:17
Related ArticlesConstitutive or Induced HIF-2 Addiction is Involved in Resistance to Anti-EGFR Treatment and Radiation Therapy in HNSCC. Cancers (Basel). 2019 Oct 21;11(10): Authors: Coliat P, Ramolu L, Jégu J, Gaiddon C, Jung AC, Pencreach E Abstract BACKGROUND: management of head and neck squamous cell carcinomas (HNSCC) include anti-Epidermal Growth Factor Receptor (EGFR) antibodies and radiotherapy, but resistance emerges in most patients. RAS mutations...
Thu Oct 24, 2019 13:17
Related ArticlesLong-term outcomes of triple semicircular canal plugging for the treatment of intractable Meniere's disease: a single center experience of 361 cases. J Vestib Res. 2019 Oct 14;: Authors: Zhang D, Lv Y, Han Y, Li Y, Li X, Wang J, Song Y, Kong L, Jian H, Fan Z, Wang H Abstract INTRODUCTION: Meniere's disease is a common chronic inner ear disease. Because the definitive pathogenesis is still unknown, there is currently no cure for this disorder....
Thu Oct 24, 2019 13:17
Related ArticlesTrends in female leadership at high-profile otolaryngology journals, 1997-2017. Laryngoscope. 2019 09;129(9):2031-2035 Authors: Litvack JR, Wick EH, Whipple ME Abstract OBJECTIVES: To determine the proportion and relative advancement of women in leadership positions at high-impact otolaryngology journals. METHODS: Nine clinical otolaryngology journals were selected based on high impact factor and subspecialty representation...
Thu Oct 24, 2019 13:17
Related ArticlesUsing word clouds to Re-envision letters of recommendation for residency applicants. Laryngoscope. 2019 09;129(9):2026-2030 Authors: Bayrak SB, Villwock JA, Villwock MR, Chiu AG, Sykes KJ Abstract OBJECTIVES/HYPOTHESIS: To develop a "word cloud"-based visual letter of recommendation (VLOR) and to evaluate its efficiency in discerning applicant quality compared to narrative letters of recommendation (NLORs). STUDY DESIGN: Cross-sectional...
Thu Oct 24, 2019 13:17
Related ArticlesUtility of deep neural networks in predicting gross-total resection after transsphenoidal surgery for pituitary adenoma: a pilot study. Neurosurg Focus. 2018 11 01;45(5):E12 Authors: Staartjes VE, Serra C, Muscas G, Maldaner N, Akeret K, van Niftrik CHB, Fierstra J, Holzmann D, Regli L Abstract OBJECTIVEGross-total resection (GTR) is often the primary surgical goal in transsphenoidal surgery for pituitary adenoma. Existing classifications...
Thu Oct 24, 2019 13:17
Related ArticlesEffects of Intraoperative Vagal Nerve Stimulation on the Gastrointestinal Microbiome in a Mouse Model of Amyotrophic Lateral Sclerosis. Comp Med. 2018 12 01;68(6):452-460 Authors: Haney MM, Ericsson AC, Lever TE Abstract The gastrointestinal microbiota (GM) plays a fundamental role in health and disease and contributes to the bidirectional signaling between the gastrointestinal system and brain. The direct line of communication between...
Thu Oct 24, 2019 13:17
Related ArticlesEngineering functional BMP-2 expressing teratoma-derived fibroblasts for enhancing osteogenesis. Sci Rep. 2018 10 01;8(1):14581 Authors: Go YY, Mun JY, Chae SW, Kim SH, Song H, Song JJ Abstract Bone morphogenetic protein 2 (BMP-2) is considered an effective growth factor for bone formation, and is used for making osteo-inductive scaffolds, but the related clinical investigations have shown low success rates. In this study, we genetically...
Thu Oct 24, 2019 13:17
Related ArticlesProvocative proposal for a revised nomenclature for allergy and other hypersensitivity diseases. Allergy. 2018 10;73(10):1939-1940 Authors: Ring J, Jutel M, Papadopoulos N, Pfaar O, Akdis C PMID: 29999176 [PubMed - indexed for MEDLINE]
Thu Oct 24, 2019 13:17
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract The taxanes or taxoids are a closely related group of antineoplastic agents that have a unique mechanism of action as inhibitors of mitosis and which are widely used in the therapy of ovarian, breast, lung, esophageal, prostate, bladder and head and neck cancers. Three taxanes are in clinical use, paclitaxel (Taxol: 1992), docetaxel (Taxotere: 1996) and...
Thu Oct 24, 2019 14:47
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract The platinum coordination complexes are a group of antineoplastic agents that are usually classified as alkylating agents, but which have distinctive features. Their anticancer activity appears to relate to the cross linking of DNA molecules in a fashion similar to standard alkylating agents. The DNA adducts formed by the platinum-containing complexes...
Thu Oct 24, 2019 14:47
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract Carboplatin is an intravenously administered platinum coordination complex and alkylating agent which is used as a chemotherapeutic agent for the treatment of various cancers, mainly ovarian, head and neck and lung cancers. Carboplatin therapy is associated with a low rate of transient serum aminotransferase elevations and with rare instances of clinically...
Thu Oct 24, 2019 14:47
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract Bleomycin is a cystotoxic antibiotic that is used as an anticancer agent in the therapy of testicular and germ cell cancers, Hodgkin disease, lymphomas and tumors of the head and neck. Therapy with bleomycin in combination with other agents is often associated with mild-to-moderate serum enzyme elevations, but is a rare cause of clinically apparent liver...
Thu Oct 24, 2019 14:47
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract Cetuximab is a chimeric mouse-human monoclonal antibody to the human epidermal growth factor (EGF) receptor which is used in the treatment of metastatic colon and head and neck cancers. Cetuximab has been linked to mild and transient serum enzyme elevations during therapy, but has not been implicated in cases of clinically apparent acute liver injury.PMID:...
Thu Oct 24, 2019 14:47
Related ArticlesLiverTox: Clinical and Research Information on Drug-Induced Liver Injury Book. 2012 Authors: Abstract Isotretinoin is a vitamin A derivative used in the treatment of severe acne and some forms of skin, head and neck cancer. Isotretinoin, like many retinoids, can lead to increase in serum aminotransferase levels, but, unlike acitretin and etretinate, isotretinoin has not been clearly implicated in cases of clinically apparent acute liver injury with jaundice.PMID:...
Thu Oct 24, 2019 14:47
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