Related Articles Internalization and Intoxication of Human Macrophages by the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent Upon Cellugyrin (Synaptogyrin-2). Front Immunol. 2020;11:1262 Authors: Boesze-Battaglia K, Dhingra A, Walker LM, Zekavat A, Shenker BJ Abstract The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is a heterotrimeric AB2 toxin capable of...
Tue Jul 14, 2020 13:20
Related Articles C-phycocyanin inhibits epithelial-to-mesenchymal transition in Caski cells. Cancer Cell Int. 2020;20:292 Authors: Ji H, Liu G, Han J, Zhu F, Dong X, Li B Abstract Background: In cervical cancer, most patients die of metastasis. The epithelial-to-mesenchymal transition (EMT) is a pivotal and intricate process that increases the metastatic potential of cervical cancer. C-phycocyanin (C-PC) is a natural marine product isolated...
Tue Jul 14, 2020 13:20
Related Articles BORA regulates cell proliferation and migration in bladder cancer. Cancer Cell Int. 2020;20:290 Authors: Cheng S, Peng T, Zhu X, Zhou F, Wang G, Ju L, Xiao Y, Liu X, Wang X Abstract Background: Bladder cancer is having a gradually increasing incidence in China. Except for the traditional chemotherapy drugs, there are no emerging new drugs for almost 30 years in bladder cancer. New potential therapeutic targets and biomarkers...
Tue Jul 14, 2020 13:20
Related Articles Identification of Two Novel Mutations in the ATM Gene from Patients with Ataxia-Telangiectasia by Whole Exome Sequencing. Curr Genomics. 2019 Nov;20(7):531-534 Authors: Heidari M, Soleyman-Nejad M, Taskhiri MH, Shahpouri J, Isazadeh A, Ahangari R, Mohamadi AR, Ebrahimi M, Karimi H, Bolhassani M, Karimi Z, Heidari M Abstract Background: Ataxia telangiectasia (AT) is one of the most common autosomal recessive hereditary ataxia...
Tue Jul 14, 2020 13:20
Related Articles Fatal adverse events in two thymoma patients treated with anti-PD-1 immune check point inhibitor and literature review. Lung Cancer. 2019 09;135:29-32 Authors: Konstantina T, Konstantinos R, Anastasios K, Anastasia M, Eleni L, Ioannis S, Sofia A, Dimitris M Abstract OBJECTIVES: Thymomas, as well as thymic carcinomas, are extremely rare tumors that arise from the thymus. The management of these tumors is primarily the complete...
Tue Jul 14, 2020 13:20
Related Articles Triphenylamine-appended cyclometallated iridium(III) complexes: Preparation, photophysical properties and application in biology/luminescence imaging. J Inorg Biochem. 2019 10;199:110757 Authors: Liu X, Hao H, Ge X, He X, Liu Y, Wang Y, Wang H, Shao M, Jing Z, Tian L, Liu Z Abstract Four triphenylamine (TPA)-appended cyclometallated iridium(III) complexes were designed and synthesized. Photophysical properties of these complexes...
Tue Jul 14, 2020 13:20
Related Articles Targeting PDZ-binding kinase is anti-tumorigenic in novel preclinical models of ACC. Endocr Relat Cancer. 2019 10;26(10):765-778 Authors: Kar A, Zhang Y, Yacob BW, Saeed J, Tompkins KD, Bagby SM, Pitts TM, Somerset H, Leong S, Wierman ME, Kiseljak-Vassiliades K Abstract Adrenocortical carcinoma (ACC) is an aggressive orphan malignancy with less than 35% 5-year survival and 75% recurrence. Surgery remains the primary therapy...
Tue Jul 14, 2020 13:20
Related Articles Aryl hydrocarbon receptor (AHR): From selected human target genes and crosstalk with transcription factors to multiple AHR functions. Biochem Pharmacol. 2019 10;168:65-70 Authors: Bock KW Abstract Accumulating evidence including studies of AHR-deficient mice and TCDD toxicity suggests multiple physiologic AHR functions. Challenges to identify responsible mechanisms are due to marked species differences and dependence upon cell...
Tue Jul 14, 2020 13:20
Related Articles Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling. Cell Death Dis. 2019 06 21;10(7):490 Authors: Spaan CN, Smit WL, van Lidth de Jeude JF, Meijer BJ, Muncan V, van den Brink GR, Heijmans J Abstract The unfolded protein response (UPR) acts through its downstream branches, PERK-eIF2α signaling, IRE1α-XBP1 signaling and ATF6 signaling. In the...
Tue Jul 14, 2020 13:20
Related Articles Mitotically heritable effects of BMAA on striatal neural stem cell proliferation and differentiation. Cell Death Dis. 2019 06 17;10(7):478 Authors: Pierozan P, Karlsson O Abstract The widespread environmental contaminant β-methylamino-L-alanine (BMAA) is a developmental neurotoxicant that can induce long-term learning and memory deficits. Studies have shown high transplacental transfer of 3H-BMAA and a significant uptake in...
Tue Jul 14, 2020 13:20
Related Articles From immune checkpoints to vaccines: The past, present and future of cancer immunotherapy. Adv Cancer Res. 2019;143:63-144 Authors: Osipov A, Murphy A, Zheng L Abstract Cancer is a worldwide medical problem with significant repercussions on individual patients and societies as a whole. In order to alter the outcomes of this deadly disease the treatment of cancer over the centuries has undergone a unique evolution. However,...
Tue Jul 14, 2020 13:20
Related Articles Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence. J Cell Sci. 2019 07 01;132(13): Authors: Liu Y, Efimova EV, Ramamurthy A, Kron SJ Abstract The binding of DNA-dependent protein kinase catalytic subunit (DNA-PKcs, also known as PRKDC) to Ku proteins at DNA double-strand breaks (DSBs) has long been considered essential for non-homologous end joining (NHEJ) repair,...
Tue Jul 14, 2020 13:20
Related Articles Durvalumab: a newly approved checkpoint inhibitor for the treatment of urothelial carcinoma. Curr Probl Cancer. 2019 06;43(3):181-194 Authors: Wills S, Hochmuth LK, Bauer KS, Deshmukh R Abstract Until a recent introduction to checkpoint inhibitors, there were limited second-line chemotherapy options for urothelial carcinoma (UC) patients with disease progression after first-line, platinum-based treatment. Outcomes for patients...
Tue Jul 14, 2020 13:20
41 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/07/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jul 14, 2020 16:53
41 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: epilepsy treatment These pubmed results were generated on 2020/07/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jul 14, 2020 13:37
Related Articles Altered Effective Connectivity of Bilateral Hippocampus in Type 2 Diabetes Mellitus. Front Neurosci. 2020;14:657 Authors: Liu T, Bai Y, Ma L, Ma X, Wei W, Zhang J, Roberts N, Wang M Abstract Patients with type 2 diabetes mellitus (T2DM) experience cognitive deficits but the underlying pathophysiologic mechanisms are not known. We therefore applied Granger causality analysis of resting-state functional magnetic resonance imaging...
Tue Jul 14, 2020 13:36
Related Articles Non-photoreceptor Expression of Tulp1 May Contribute to Extensive Retinal Degeneration in Tulp1-/- Mice. Front Neurosci. 2020;14:656 Authors: Palfi A, Yesmambetov A, Humphries P, Hokamp K, Farrar GJ Abstract Mutations in tubby like protein 1 gene (TULP1) are causative of early-onset recessive inherited retinal degenerations (IRDs); similarly, the Tulp1-/- mouse is also characterized by a rapid IRD. Tulp1 mRNA and protein expression...
Tue Jul 14, 2020 13:36
Related Articles KTN1 Variants Underlying Putamen Gray Matter Volumes and Parkinson's Disease. Front Neurosci. 2020;14:651 Authors: Mao Q, Wang X, Chen B, Fan L, Wang S, Zhang Y, Lin X, Cao Y, Wu YC, Ji J, Xu J, Zheng J, Zhang H, Zheng C, Chen W, Cheng W, Luo X, Wang K, Zuo L, Kang L, Li CR, Luo X Abstract Background: Selective loss of dopaminergic neurons and diminished putamen gray matter volume (GMV) represents a central feature of Parkinson's...
Tue Jul 14, 2020 13:36
Related Articles Toll-Like Receptor 4 in the Rat Caudal Medulla Mediates Tooth Pulp Inflammatory Pain. Front Neurosci. 2020;14:643 Authors: Filippini HF, Molska GR, Zanjir M, Arudchelvan Y, Gong SG, Campos MM, Avivi-Arber L, Sessle BJ Abstract The aims of this study were to investigate if Toll-like receptor 4 (TLR4) is expressed in the medullary dorsal horn (MDH) and if medullary application of a TLR4 antagonist (lipopolysaccharides from Rhodobacter...
Tue Jul 14, 2020 13:36
Prevention of Neurite Spine Loss Induced by Dopamine D2 Receptor Overactivation in Striatal Neurons.
Related Articles Prevention of Neurite Spine Loss Induced by Dopamine D2 Receptor Overactivation in Striatal Neurons. Front Neurosci. 2020;14:642 Authors: Zheng P, Su QP, Jin D, Yu Y, Huang XF Abstract Psychosis has been considered a disorder of impaired neuronal connectivity. Evidence for excessive formation of dopamine D2 receptor (D2R) - disrupted in schizophrenia 1 (DISC1) complexes has led to a new perspective on molecular mechanisms involved...
Tue Jul 14, 2020 13:36
Related Articles Disrupted Sleep and Circadian Rhythms in Schizophrenia and Their Interaction With Dopamine Signaling. Front Neurosci. 2020;14:636 Authors: Ashton A, Jagannath A Abstract Sleep and circadian rhythm disruption (SCRD) is a common feature of schizophrenia, and is associated with symptom severity and patient quality of life. It is commonly manifested as disturbances to the sleep/wake cycle, with sleep abnormalities occurring in up...
Tue Jul 14, 2020 13:36
Related Articles BETA: A Large Benchmark Database Toward SSVEP-BCI Application. Front Neurosci. 2020;14:627 Authors: Liu B, Huang X, Wang Y, Chen X, Gao X Abstract The brain-computer interface (BCI) provides an alternative means to communicate and it has sparked growing interest in the past two decades. Specifically, for Steady-State Visual Evoked Potential (SSVEP) based BCI, marked improvement has been made in the frequency recognition method...
Tue Jul 14, 2020 13:36
Related Articles Phospho-HDAC6 Gathers Into Protein Aggregates in Parkinson's Disease and Atypical Parkinsonisms. Front Neurosci. 2020;14:624 Authors: Mazzetti S, De Leonardis M, Gagliardi G, Calogero AM, Basellini MJ, Madaschi L, Costa I, Cacciatore F, Spinello S, Bramerio M, Cilia R, Rolando C, Giaccone G, Pezzoli G, Cappelletti G Abstract HDAC6 is a unique histone deacetylase that targets cytoplasmic non-histone proteins and has a specific...
Tue Jul 14, 2020 13:36
Related Articles Randomized, Double-Blind Assessment of LFP Versus SUA Guidance in STN-DBS Lead Implantation: A Pilot Study. Front Neurosci. 2020;14:611 Authors: Ozturk M, Telkes I, Jimenez-Shahed J, Viswanathan A, Tarakad A, Kumar S, Sheth SA, Ince NF Abstract Background: The efficacy of deep brain stimulation (DBS) therapy in Parkinson's disease (PD) patients is highly dependent on the precise localization of the target structures such as...
Tue Jul 14, 2020 13:36
Related Articles Epilepsy EEG Signal Classification Algorithm Based on Improved RBF. Front Neurosci. 2020;14:606 Authors: Zhou D, Li X Abstract Epilepsy is a chronic recurrent transient brain dysfunction syndrome. It is characterized by recurrent epilepsy caused by abnormal discharge of brain neurons. Epilepsy is one of the common diseases in nervous system. The analysis of EEG signals is a hot topic in current research. In order to solve the...
Tue Jul 14, 2020 13:36
Related Articles Improvements to Healthspan Through Environmental Enrichment and Lifestyle Interventions: Where Are We Now? Front Neurosci. 2020;14:605 Authors: Queen NJ, Hassan QN, Cao L Abstract Environmental enrichment (EE) is an experimental paradigm that is used to explore how a complex, stimulating environment can impact overall health. In laboratory animal experiments, EE housing conditions typically include larger-than-standard cages,...
Tue Jul 14, 2020 13:36
Related Articles Enhanced Accuracy for Multiclass Mental Workload Detection Using Long Short-Term Memory for Brain-Computer Interface. Front Neurosci. 2020;14:584 Authors: Asgher U, Khalil K, Khan MJ, Ahmad R, Butt SI, Ayaz Y, Naseer N, Nazir S Abstract Cognitive workload is one of the widely invoked human factors in the areas of human-machine interaction (HMI) and neuroergonomics. The precise assessment of cognitive and mental workload (MWL)...
Tue Jul 14, 2020 13:36
Related Articles Brain White Matter Correlates of Creativity in Schizophrenia: A Diffusion Tensor Imaging Study. Front Neurosci. 2020;14:572 Authors: Sampedro A, Peña J, Ibarretxe-Bilbao N, Cabrera-Zubizarreta A, Sánchez P, Gómez-Gastiasoro A, Iriarte-Yoller N, Pavón C, Ojeda N Abstract The relationship between creativity and psychopathology has been a controversial research topic for decades. Specifically, it has been shown that people with...
Tue Jul 14, 2020 13:36
Related Articles Supraspinal and Afferent Signaling Facilitate Spinal Sensorimotor Network Excitability After Discomplete Spinal Cord Injury: A Case Report. Front Neurosci. 2020;14:552 Authors: Militskova A, Mukhametova E, Fatykhova E, Sharifullin S, Cuellar CA, Calvert JS, Grahn PJ, Baltina T, Lavrov I Abstract Objective: In this study, we evaluated the role of residual supraspinal and afferent signaling and their convergence on the sublesional...
Tue Jul 14, 2020 13:36
Related Articles An On-chip Spiking Neural Network for Estimation of the Head Pose of the iCub Robot. Front Neurosci. 2020;14:551 Authors: Kreiser R, Renner A, Leite VRC, Serhan B, Bartolozzi C, Glover A, Sandamirskaya Y Abstract In this work, we present a neuromorphic architecture for head pose estimation and scene representation for the humanoid iCub robot. The spiking neuronal network is fully realized in Intel's neuromorphic research chip,...
Tue Jul 14, 2020 13:36
Related Articles Synchrony Between Default-Mode and Sensorimotor Networks Facilitates Motor Function in Stroke Rehabilitation: A Pilot fMRI Study. Front Neurosci. 2020;14:548 Authors: Wu CW, Lin SN, Hsu LM, Yeh SC, Guu SF, Lee SH, Chen CC Abstract Stroke is the most common cause of complex disability in Taiwan. After stroke onset, persistent physical practice or exercise in the rehabilitation procedure reorganizes neural assembly for reducing...
Tue Jul 14, 2020 13:36
Subcortical Dopamine and Cognition in Schizophrenia: Looking Beyond Psychosis in Preclinical Models.
Related Articles Subcortical Dopamine and Cognition in Schizophrenia: Looking Beyond Psychosis in Preclinical Models. Front Neurosci. 2020;14:542 Authors: Conn KA, Burne THJ, Kesby JP Abstract Schizophrenia is characterized by positive, negative and cognitive symptoms. All current antipsychotic treatments feature dopamine-receptor antagonism that is relatively effective at addressing the psychotic (positive) symptoms of schizophrenia. However,...
Tue Jul 14, 2020 13:36
Related Articles A Survey on the Use of Haptic Feedback for Brain-Computer Interfaces and Neurofeedback. Front Neurosci. 2020;14:528 Authors: Fleury M, Lioi G, Barillot C, Lécuyer A Abstract Neurofeedback (NF) and brain-computer interface (BCI) applications rely on the registration and real-time feedback of individual patterns of brain activity with the aim of achieving self-regulation of specific neural substrates or control of external devices....
Tue Jul 14, 2020 13:36
Related Articles Ethanol-Induced Alterations in Placental and Fetal Cerebrocortical Annexin-A4 and Cerebral Cavernous Malformation Protein 3 Are Associated With Reductions in Fetal Cortical VEGF Receptor Binding and Microvascular Density. Front Neurosci. 2020;14:519 Authors: Savage DD, Rosenberg MJ, Coquet L, Porch MW, Allen NA, Roux C, Aligny C, Jouenne T, Gonzalez BJ Abstract Jegou et al. (2012) have reported prenatal alcohol exposure (PAE)-induced...
Tue Jul 14, 2020 13:36
Related Articles Editorial: The Role of Stem Cells, Epigenetics and MicroRNAs in Parkinson's Disease. Front Neurosci. 2020;14:515 Authors: Hegarty SV, Green HF, Niclis J, O'Keeffe GW, Sullivan AM PMID: 32655345 [PubMed]
Tue Jul 14, 2020 13:36
Related Articles A Review of Sensory Feedback in Upper-Limb Prostheses From the Perspective of Human Motor Control. Front Neurosci. 2020;14:345 Authors: Sensinger JW, Dosen S Abstract This manuscript reviews historical and recent studies that focus on supplementary sensory feedback for use in upper limb prostheses. It shows that the inability of many studies to speak to the issue of meaningful performance improvements in real-life scenarios...
Tue Jul 14, 2020 13:36
46 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jul 14, 2020 14:40
46 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/07/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Jul 14, 2020 13:39
Related Articles Antibody-drug conjugates in breast cancer: the chemotherapy of the future? Curr Opin Oncol. 2020 Jul 09;: Authors: Nicolò E, Zagami P, Curigliano G Abstract PURPOSE OF REVIEW: Antibody-drug conjugates (ADCs) represent an interesting new class of anticancer agents, capable of exploiting the specificity of monoclonal antibodies toward cellular-antigens for a targeted release of potent cytotoxic drugs, with a potential increased...
Tue Jul 14, 2020 14:50
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