Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Mon Jul 06, 2020 07:02
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundScars with poor cosmesis that develop after wound healing may affect normal life.ObjectiveTo assess the efficacy and safety of botulinum toxin type A (BTXA) in preventing postoperative hypertrophic scars or keloids.MethodsA systematic review was performed by searching the PubMed, Cochrane Library, and EMBASE databases from their inception date up to February 2020 for randomized controlled trials (RCTs) evaluating the efficacy of...
Wed Jul 01, 2020 06:20
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Tue Jun 30, 2020 05:06
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Mon Jun 29, 2020 10:04
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundIn Québec, targeted biologic therapies for moderate to severe plaque psoriasis are restricted to patients who have not responded to phototherapy or conventional systemic treatment, primarily due to high drug costs. Apremilast, an oral treatment for plaque psoriasis, was added to the Québec provincial health insurance plan (Régie de l’assurance maladie du Québec; RAMQ) formulary in 2015, making this the only province in Canada with...
Mon Jun 29, 2020 06:38
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundSeveral treatments for plaque psoriasis are available, but it remains challenging for physicians to make informed treatment decisions due to a lack of head-to-head trials.ObjectivesThis network meta-analysis (NMA) compares the efficacy of brodalumab to other biologic agents in Canada for moderate-to-severe plaque psoriasis.MethodsA systematic literature review of randomized controlled trials (RCTs) published before October 2017...
Fri Jun 26, 2020 14:16
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Thu Jun 25, 2020 06:07
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Wed Jun 24, 2020 07:03
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Tue Jun 23, 2020 05:50
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Mon Jun 22, 2020 11:11
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Mon Jun 22, 2020 10:39
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Mon Jun 22, 2020 10:27
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Fri Jun 19, 2020 05:42
Journal of Cutaneous Medicine and Surgery, Ahead of Print.
Wed Jun 17, 2020 06:43
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Gray zone lymphoma, also known as B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma, is a rare malignancy with overlapping features of both diffuse large B-cell lymphoma and classical Hodgkin lymphoma. Most commonly mediastinal involvement is seen. Extranodal involvement is rare. In this case report, we present the case...
Tue Jul 14, 2020 11:28
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Pulmonary autograft, or Ross procedure, is performed by supplanting a diseased aortic valve with the patient’s own pulmonary valve. Reconstruction of the right ventricular outflow tract is then completed using a pulmonary homograft. To our knowledge, infective endocarditis occurring decades after the Ross procedure has not been reported. Diligent echocardiographic examination can be crucial to ensure...
Tue Jul 14, 2020 11:27
Publication date: Available online 13 July 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Yale Tung Chen, Milagros Martí de Gracia, Aurea Díez-Tascón, Rodrigo Alonso-González, Pablo Rodríguez-Fuertes, Maria Luz Parra-Gordo, Silvia Ossaba-Vélez, Sergio Agudo-Fernández, Rafael Llamas Fuertes
Tue Jul 14, 2020 12:49
Publication date: Available online 13 July 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): F.J. Dieleman, G.J. Meijer, M.A.W. Merkx
Tue Jul 14, 2020 12:37
In this study, we conducted a detailed analysis of the digit ratio patterns (2D:3D, 2D:4D and 3D:4D) in Lacerta agilis , Lacertidae and Squamata. Obtained results indicated a clear dimorphic pattern for most digit ratios, whereby the digit ratios of all four limbs were significantly lower in females than in males. Furthermore, a clear relationship between caudal autotomy and right forelimb 2D:4D ratio has been shown, such that individuals with autotomy are characterized by higher 2D:4D ratios....
Mon Jul 13, 2020 11:43
Comparison of the typical structure of 3D reconstructed seminal vesicles: (a) dissected seminal vesicle, (b) surface of the 3D reconstruction and (c) luminal structure of the 3D reconstruction. Abstract The seminal vesicles are the glands of male reproductive organs that produce the fluid and nutrient constituents of semen. It has been believed for a long time that the lumen of a seminal vesicle was a single‐coiled tubular structure with irregular diverticula. There are several previous reports...
Mon Jul 13, 2020 11:41
Red Langur, Borneo. Abstract The aim of this article is to explore the impact of coronavirus disease (COVID‐19) pandemic on primate‐related conservation work. The withdrawal of primatologists and conservation staff from field research can lead to a number of detrimental effects not just on conservation but also on local communities in low‐ and middle‐income countries. Inequalities in access to health and financial insecurities may be drivers for the illegal wildlife trade and the lack of tourism...
Mon Jul 13, 2020 21:10
Abstract Oral health‐related quality of life (OHRQOL) is the component of health‐related quality of life that relates to the effects of oral diseases and dental interventions on patients. This article describes why OHRQOL is important and how it is measured. The conceptual basis for OHRQOL is discussed. A four‐dimensional structure consisting of Oral Function , Orofacial Pain , Orofacial Appearance and Psychosocial Impact as the OHRQOL dimensions has emerged as psychometrically sound and clinically...
Mon Jul 13, 2020 15:32
Abstract Purpose of Review Primary age-related tauopathy (PART) was recently proposed as a pathologic diagnosis for brains that harbor neurofibrillary tangles (Braak stage ≤ 4) with little, if any, amyloid burden. We sought to review the clinicopathologic findings related to PART. Recent Findings Most adult human brains show at least...
Tue Jul 14, 2020 03:00
The order of the authors was inadvertently inverted; Dr. Alyahya is the intended first author.
Tue Jul 14, 2020 03:00
Abstract Purpose of Review Depression and anxiety substantially contribute to interictal disability in patients with epilepsy (PWE). This review summarizes current studies that shed light on mechanisms of comorbidity. Recent Findings Mounting epidemiological data implicate shared risk factors for anxiety/depression and seizure propensity,...
Tue Jul 14, 2020 03:00
Background: Immunosuppressive therapy still is the standard treatment for patients with connective tissue disease-associated interstitial lung disease (CTD-ILD). Objectives: This retrospective study aimed to provide data on the tolerability and efficacy of azathioprine in progressive CTD-ILDs. Methods: A total of 56 patients with CTD-ILD treated with azathioprine between 2003 and 2014 were included in the study. The patients were assessed every 3 months during follow-up. Results: The mean treatment...
Tue Jul 14, 2020 08:08
Abstract Desmoplastic small round cell tumor (DSRCT) is rare and a highly aggressive neoplasm that typically involves the soft tissues of the abdomen or pelvis in children or young adults, showing a male predilection. Although it can occurs over a wide age range, the peak incidence is in the third decade of life. DSRCT usually shows widespread abdominal serosal involvement, and overall patient survival is poor. On the other hand, extra‐abdominal DSRCT is very rare. DSRCT in major salivary glands...
Mon Jul 13, 2020 15:15
Abstract Monitoring survival of cancer patients using data collected by population‐based cancer registries is an important component of cancer control. In this setting, patient survival is often summarized using net survival, that is survival from cancer if there were no other possible causes of death. Although net survival is the gold standard for comparing survival between groups or over time, it is less relevant for understanding the anticipated real‐world prognosis of patients....
Mon Jul 13, 2020 11:18
Abstract Synaptic downscaling during sleep, a physiological process to restore synaptic homeostasis and maintain learning efficiency and healthy brain development, has been related to a reduction of the slope of sleep slow waves (SSW). However, such synaptic downscaling seems not to be reflected in high‐amplitude SSW. Recently we have shown reduced SSW slopes during hormonal treatment (adrenocorticotrophic hormone, prednisolone) in patients with West syndrome (WS). Yet, whether this reduction was...
Mon Jul 13, 2020 14:54
Abstract Purpose Many deaf children have limited access to language, spoken or signed, during early childhood – which has damaging effects on many aspects of development. There has been a recent shift to consider deafness and language deprivation as separate but related conditions. As such, educational plans should differentiate between services related to deafness and services related to language deprivation. ...
Tue Jul 14, 2020 03:00
Abstract Purpose Sleep disturbances and poor sleep quality are known to be present in patients with CF. Regular physical activity plays an important role in the treatment of CF patients due to its positive influence on progression of disease and quality of life. The aim of this work is to create a home-based sleep and activity profile and to investigate the influence of habitual physical activity (HPA) on sleep quality in children,...
Tue Jul 14, 2020 03:00
Helicobacter pylori (H. pylori) is the most common cause of gastric ulcer; however, its association with gastric cancer has been proved through a variety of studies. Importantly, H. pylori infection affects around half of the world’s population leading to a variety of gastric problems and is mostly present in asymptomatic form. Although about 20% of people infected with H. pylori develop preneoplastic gastric lesions in later stages of their life, around 2% of infected individuals develop gastric...
Mon Jul 13, 2020 18:50
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectivePatients with type 2 diabetes (T2DM) are prone to cardiovascular disease, and both conditions are linked to oxidative DNA damage, which produces 8-hydroxy-2′-deoxyguanosine (8-OHdG). We investigated the impact of 8-OHdG on coronary heart disease (CHD) in elderly patients with T2DM.MethodsWe assessed the demographic, clinical, and biochemical characteristics of 147 patients with T2DM (mean age 73.29 ± 8.19 years) with...
Tue Jul 14, 2020 07:11
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveLong non-coding RNAs (lncRNAs) are involved in carcinogenesis and could be used as diagnostic biomarkers. Our study aimed to elucidate the clinical role of serum exosomal lncRNA H19 in gastric cancer (GC).MethodsIn this prospective clinical study, we determined serum exosomal lncRNA H19 levels in 81 patients with GC and analysed the correlations between serum lncRNA H19 levels and clinical characteristics. Receiver...
Tue Jul 14, 2020 07:10
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Most patients with primary central system lymphoma (PCNSL) have immune dysfunction. PCNSL without immune dysfunction is rare and extremely challenging to diagnose. Here, we report the case of a 52-year-old woman without immune dysfunction who presented with PCNSL. The patient died a few months after diagnosis and during treatment. A review of this PCNSL patient’s case highlighted that poor interpretation of imaging features...
Tue Jul 14, 2020 07:10
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectivesWe aimed to evaluate the diagnostic value of the combination of the monocyte-to-high-density lipoprotein cholesterol ratio (MHR) with the monocyte-to-lymphocyte ratio (MLR) in ischemic stroke patients.MethodsThere were 253 patients who were diagnosed with ischemic stroke and 211 healthy subjects enrolled into this retrospective study.ResultMHR and MLR were significantly higher in ischemic stroke patients compared...
Tue Jul 14, 2020 07:10
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveWe performed this meta-analysis to compare the efficacy and toxicity of regorafenib and TAS-102.MethodsElectronic databases were searched to identify studies comparing the efficacy and safety of regorafenib and TAS-102 in patients with chemotherapy-refractory metastatic colorectal cancer using pooled analyses.ResultsThree clinical trials were included in this analysis. Regarding the reasons for treatment discontinuation,...
Tue Jul 14, 2020 07:09
Abstract Can the theory of conceptual spaces developed by Peter Gärdenfors (2000, 2014) and others be applied to moral issues? Martin Peterson (2017) argues that several moral principles can be construed as regions in a shared similarity space, but Kristin Shrader-Frechette (2017) and Gert-Jan Lokhorst (2018) question Peterson’s claim. They argue that the moral similarity judgments used to construct the space are underspecified and subjective. In this paper, we present new data...
Tue Jul 14, 2020 03:00
Abstract Introduction A number of studies have reported that pre-pregnancy overweight status is associated with offspring obesity, yet only a few studies have examined pre-pregnancy underweight status as it associates with offspring health. The aim of the present study was to assess the effect of pre-pregnancy underweight status in a mother on health outcomes in her offspring. To this end, the primary outcome examined in the present...
Mon Jul 13, 2020 03:00
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